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Leser–Trélat Sign
The Leser–Trélat sign is the explosive onset of multiple seborrheic keratoses (many pigmented skin lesions), often with an inflammation, inflammatory base. This can be a sign of internal malignancy as part of a paraneoplastic syndrome. In addition to the development of new lesions, preexisting ones frequently increase in size and become symptomatic. Associations Although most associated neoplasms are gastrointestinal adenocarcinomas (Gastric adenocarcinoma, stomach, Liver cancer, liver, Colorectal adenocarcinoma, colorectal and Pancreatic adenocarcinoma, pancreas), malignancies of the Breast cancer, breast, Lung cancer, lung, and Bladder cancer, urinary tract, as well as Lymphoma, lymphoid tissue, have been associated with this distinctive rash. It is likely that various cytokines and other growth factors produced by the neoplasm are responsible for the abrupt appearance of the seborrheic keratoses. In some cases, paraneoplastic acanthosis nigricans (35% of patients), florid c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Seborrheic Keratosis On Human Back
Seborrhoeic dermatitis (also spelled seborrheic dermatitis in American English) is a long-term skin disorder. Symptoms include flaky, scaly, greasy, and occasionally itchy and inflamed skin. Areas of the skin rich in sebum, oil-producing glands are often affected including the scalp, face, and chest. It can result in social or self-esteem problems. In babies, when the scalp is primarily involved, it is called cradle cap. Mild seborrhoeic dermatitis of the scalp may be described in lay terms as dandruff due to the dry, flaky character of the skin. However, as dandruff may refer to any dryness or scaling of the scalp, not all dandruff is seborrhoeic dermatitis. Seborrhoeic dermatitis is sometimes inaccurately referred to as seborrhoea. The cause is unclear but believed to involve a number of genetic and environmental factors. Risk factors for seborrhoeic dermatitis include immunocompromised, poor immune function, Parkinson's disease, and alcoholic pancreatitis. The condition ma ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
