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Lawrence A. Loeb
Lawrence A. "Larry" Loeb is an American cancer researcher and genome scientist. He is a professor of pathology and biochemistry at the University of Washington. Loeb is best known for his work on the fidelity of DNA polymerase, and his proposal of the mutator phenotype hypothesis in cancers. Biography Loeb was born in Poughkeepsie, New York, Poughkeepsie, New York.  He enrolled in the City College of New York at age 17, earning his bachelor's degree in 1957.  In 1958, he matriculated at New York University Grossman School of Medicine, Bellevue Hospital Medical College earning his medical doctorate three years later.  Loeb completed his medical internship at Stanford University from 1961 to 1962. Loeb left medical practice for scientific research, serving as a research associate with Harry Gelboin, Harry V. Gelboin at the National Cancer Institute from 1962 to 1964.  He then resumed work as a research associate with Daniel Mazia at the University of California, Berkeley, and u ...
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Poughkeepsie, New York
Poughkeepsie ( ), officially the City of Poughkeepsie, separate from the Town of Poughkeepsie around it) is a city in the U.S. state of New York. It is the county seat of Dutchess County, with a 2020 census population of 31,577. Poughkeepsie is in the Hudson River Valley region, midway between the core of the New York metropolitan area and the state capital of Albany. It is a principal city of the Poughkeepsie–Newburgh–Middletown metropolitan area which belongs to the New York combined statistical area. It is served by the nearby Hudson Valley Regional Airport and Stewart International Airport in Orange County, New York. Poughkeepsie has been called "The Queen City of the Hudson". It was settled in the 17th century by the Dutch and became New York State's second capital shortly after the American Revolution. It was chartered as a city in 1854. Major bridges in the city include the Walkway over the Hudson, a former railroad bridge called the Poughkeepsie Bridge whic ...
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Harry Gelboin
Harry V. Gelboin (1929–2010) was an American cancer research scientist, particularly in chemical carcinogenesis. From 1966 to 1999, he was Chief of the Laboratory of Molecular Carcinogenics (now called the Laboratory of Metabolism) at the National Cancer Institute (NCI), part of the National Institutes of Health (NIH). His research focused on the activation and detoxification of drugs and carcinogens. He is best known for his studies of the genetic mechanisms by which normal cells transform into malignancy, which constituted a major advance in cancer research. Biography Gelboin was born in Chicago in 1929, the oldest child of Eva (Jurkowsky/Jerkowsky) and Herman Gelboim, recent immigrants from Poland and Russia. He had one younger sister, Helen Friedman. He grew up in a working class Jewish family in the Humboldt Park section of Chicago. His parents ran a stall and later a store at Chicago's Maxwell Street market. He attended Chicago public schools, graduating from ...
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American Cancer Researchers
American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, people who self-identify their ancestry as "American" ** American English, the set of varieties of the English language native to the United States ** Native Americans in the United States, indigenous peoples of the United States * American, something of, from, or related to the Americas, also known as "America" ** Indigenous peoples of the Americas * American (word), for analysis and history of the meanings in various contexts Organizations * American Airlines, U.S.-based airline headquartered in Fort Worth, Texas * American Athletic Conference, an American college athletic conference * American Recordings (record label), a record label previously known as Def American * American University, in Washington, D.C. Sports teams Soccer * ...
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Living People
Related categories * :Year of birth missing (living people) / :Year of birth unknown * :Date of birth missing (living people) / :Date of birth unknown * :Place of birth missing (living people) / :Place of birth unknown * :Year of death missing / :Year of death unknown * :Date of death missing / :Date of death unknown * :Place of death missing / :Place of death unknown * :Missing middle or first names See also * :Dead people * :Template:L, which generates this category or death years, and birth year and sort keys. : {{DEFAULTSORT:Living people 21st-century people People by status ...
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1936 Births
Events January–February * January 20 – George V of the United Kingdom and the British Dominions and Emperor of India, dies at his Sandringham Estate. The Prince of Wales succeeds to the throne of the United Kingdom as King Edward VIII. * January 28 – Britain's King George V state funeral takes place in London and Windsor. He is buried at St George's Chapel, Windsor Castle * February 4 – Radium E (bismuth-210) becomes the first radioactive element to be made synthetically. * February 6 – The 1936 Winter Olympics, IV Olympic Winter Games open in Garmisch-Partenkirchen, Germany. * February 10–February 19, 19 – Second Italo-Ethiopian War: Battle of Amba Aradam – Italian forces gain a decisive tactical victory, effectively neutralizing the army of the Ethiopian Empire. * February 16 – 1936 Spanish general election: The left-wing Popular Front (Spain), Popular Front coalition takes a majority. * February 26 – February 26 Inci ...
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American Academy Of Arts And Sciences
The American Academy of Arts and Sciences (abbreviation: AAA&S) is one of the oldest learned societies in the United States. It was founded in 1780 during the American Revolution by John Adams, John Hancock, James Bowdoin, Andrew Oliver, and other Founding Fathers of the United States. It is headquartered in Cambridge, Massachusetts. Membership in the academy is achieved through a thorough petition, review, and election process. The academy's quarterly journal, '' Dædalus'', is published by MIT Press on behalf of the academy. The academy also conducts multidisciplinary public policy research. History The Academy was established by the Massachusetts legislature on May 4, 1780, charted in order "to cultivate every art and science which may tend to advance the interest, honor, dignity, and happiness of a free, independent, and virtuous people." The sixty-two incorporating fellows represented varying interests and high standing in the political, professional, and commerc ...
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Harvard University
Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Founded in 1636 as Harvard College and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of higher learning in the United States and one of the most prestigious and highly ranked universities in the world. The university is composed of ten academic faculties plus Harvard Radcliffe Institute. The Faculty of Arts and Sciences offers study in a wide range of undergraduate and graduate academic disciplines, and other faculties offer only graduate degrees, including professional degrees. Harvard has three main campuses: the Cambridge campus centered on Harvard Yard; an adjoining campus immediately across Charles River in the Allston neighborhood of Boston; and the medical campus in Boston's Longwood Medical Area. Harvard's endowment is valued at $50.9 billion, making it the wealthiest academic institution in the world. Endo ...
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AACR Awards
The American Association for Cancer Research gives several annual awards for significant contributions to the field of cancer research. AACR Award for Lifetime Achievement in Cancer Research This award recognizes prodigious scientists that have made profound contributions to the field of cancer research. * 2018: Joseph R. Bertino * 2017: Mina Bissell * 2016: Robert A. Weinberg * 2015: Mario R. Capecchi * 2014: Douglas Hanahan * 2013: Harold L. Moses * 2012: Beatrice Mintz * 2011: Susan Band Horwitz * 2010: Janet D. Rowley * 2009: Joseph F. Fraumeni, Jr. * 2008: Harald zur Hausen * 2007: Donald Metcalf * 2006: Bernard Fisher * 2005: Alfred G. Knudson, Jr. * 2004: Emil Frei III AACR Award for Outstanding Achievement in Cancer Research This award recognizes the outstanding research of investigators under the age of 40. * This award has not been given since 2016. * 2016: Franziska Michor * 2015: Christopher R. Vakoc * 2014: Nima Sharifi * 2013: Roger S. Lo * 2012: Yibin ...
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American Association For The Advancement Of Science
The American Association for the Advancement of Science (AAAS) is an American international non-profit organization with the stated goals of promoting cooperation among scientists, defending scientific freedom, encouraging scientific responsibility, and supporting scientific education and science outreach for the betterment of all humanity. It is the world's largest general scientific society, with over 120,000 members, and is the publisher of the well-known scientific journal ''Science''. History Creation The American Association for the Advancement of Science was created on September 20, 1848, at the Academy of Natural Sciences in Philadelphia, Pennsylvania. It was a reformation of the Association of American Geologists and Naturalists. The society chose William Charles Redfield as their first president because he had proposed the most comprehensive plans for the organization. According to the first constitution which was agreed to at the September 20 meeting, the goal ...
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American College Of Physicians
The American College of Physicians (ACP) is a national organization of internists, who specialize in the diagnosis, treatment, and care of adults.Sokanu "What is an Internist?" Retrieved October 20, 2014 With 161,000 members, ACP is the largest medical-specialty organization and second-largest physician group in the United States, after the American Medical Association.Osmosis "Prep for the Medicine Shelf". Retrieved October 20, 2014 Its flagship journal, the ''Annals of Internal Medicine'', is considered one of the five top medical journals in the United States and Britain. Mission and history Founded in 1915, ACP's stated mission is to "enhance the quality and effectiveness of health care by fostering excellence and professionalism in the practice of medicine." In 1998, it merged with the American Society of Internal Medicine (ASIM). ASIM's focus on the economic, political, and social aspects of medical care both enlarged and complemented its mission. Known as ACP-ASIM from ...
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Jonas Salk
Jonas Edward Salk (; born Jonas Salk; October 28, 1914June 23, 1995) was an American virologist and medical researcher who developed one of the first successful polio vaccines. He was born in New York City and attended the City College of New York and New York University School of Medicine. In 1947, Salk accepted a professorship in the School of Medicine at the University of Pittsburgh. It was there that he undertook a project to determine the number of different types of poliovirus, starting in 1948. For the next seven years, Salk devoted himself towards developing a vaccine against polio. Salk was immediately hailed as a "miracle worker" when the vaccine's success was first made public in April 1955, and chose to not patent the vaccine or seek any profit from it in order to maximize its global distribution. The National Foundation for Infantile Paralysis and the University of Pittsburgh looked into patenting the vaccine but, since Salk's techniques were not novel, their p ...
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Duplex Sequencing
Duplex sequencing is a library preparation and analysis method for next-generation sequencing (NGS) platforms that employs random tagging of double-stranded DNA to detect mutations with higher accuracy and lower error rates. This method uses degenerate molecular tags in addition to sequencing adapters to recognize reads originating from each strand of DNA. The generated sequencing reads then will be analyzed using two methods: single-strand consensus sequences (SSCS) and duplex consensus sequences (DCS) assembly. Duplex sequencing theoretically can detect mutations with frequencies as low as 5 x 10−8 --that is more than 10,000 times higher in accuracy compared to the conventional next-generation sequencing methods.M. W. Schmitt, S. R. Kennedy, J. J. Salk, et al“Detection of ultra-rare mutations by next-generation sequencing” Proc. Natl. Acad. Sci., vol. 109 no. 36. 2012. .S. R. Kennedy, M. W. Schmitt, E. J. Fox, B. F. Kohrn, et al Nature Protoc., vol. 9 no. 11, 2586-606. 2 ...
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