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Lafayette Mendel
Lafayette Benedict Mendel (February 5, 1872 – December 9, 1935) was an American biochemist known for his work in nutrition, with longtime collaborator Thomas B. Osborne, including the study of Vitamin A, Vitamin B, lysine and tryptophan. Life Mendel was born in Delhi, New York, son of Benedict Mendel, a merchant born in Aufhausen, Germany in 1833, and Pauline Ullman, born in Eschenau, Germany. His father immigrated to the United States from Germany in 1851, his mother in 1870."Lafayette Benedict Mendel." World of Biology. Farmington Hills, Mich.: Thomson Gale. 2006. At 15, he won a New York State scholarship. Mendel studied classics, economics and the humanities, as well as biology and chemistry at |
Delhi (town), New York
Delhi ( ) is a town in Delaware County, New York, United States. The population was 4,795 at the 2020 census.US Census Bureau, 2020 Census, Delhi town, Delaware County, New York https://www.census.gov/search-results.html?searchType=web&cssp=SERP&q=Delhi%20town,%20Delaware%20County,%20New%20York The town is in the east-central part of the county and contains the village of Delhi. The State University of New York at Delhi is located in the town. The town is named after the city of Delhi, the capital of India. The name was in honor of founder Ebenezer Foote, who was known as "The Great Mogul". Another founder, Erastus Root, a rival of Foote, is responsible for the pronunciation. Root preferred the name "Mapleton". When he learned the town was to be named Delhi, he exclaimed, "Delhi, Hell-high! Might as well call it Foote-high." The town is the setting of the 1959 novel ''My Side of the Mountain'' by Jean Craighead George. History Delhi was formed from the towns of Kortright, Midd ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Germany
Germany, officially the Federal Republic of Germany (FRG),, is a country in Central Europe. It is the most populous member state of the European Union. Germany lies between the Baltic and North Sea to the north and the Alps to the south. Its 16 constituent states have a total population of over 84 million in an area of . It borders Denmark to the north, Poland and Czechia to the east, Austria and Switzerland to the south, and France, Luxembourg, Belgium, and the Netherlands to the west. The nation's capital and most populous city is Berlin and its main financial centre is Frankfurt; the largest urban area is the Ruhr. Settlement in what is now Germany began in the Lower Paleolithic, with various tribes inhabiting it from the Neolithic onward, chiefly the Celts. Various Germanic tribes have inhabited the northern parts of modern Germany since classical antiquity. A region named Germania was documented before AD 100. In 962, the Kingdom of Germany formed the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Castor Oil Plant
''Ricinus communis'', the castor bean or castor oil plant, is a species of perennial flowering plant in the spurge family, Euphorbiaceae. It is the sole species in the monotypic genus, ''Ricinus'', and subtribe, Ricininae. The evolution of castor and its relation to other species are currently being studied using modern genetic tools. It reproduces with a mixed pollination system which favors selfing by geitonogamy but at the same time can be an out-crosser by anemophily (wind pollination) or entomophily (insect pollination). Its seed is the castor bean, which, despite its name, is not a bean (that is, the seed of many Fabaceae). Castor is indigenous to the southeastern Mediterranean Basin, Eastern Africa, and India, but is widespread throughout tropical regions (and widely grown elsewhere as an ornamental plant). Castor seed is the source of castor oil, which has a wide variety of uses. The seeds contain between 40% and 60% oil that is rich in triglycerides, mainly ricino ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ribosome Inactivating Protein
A ribosome-inactivating protein (RIP) is a protein synthesis inhibitor that acts at the eukaryotic ribosome. This protein family describes a large family of such proteins that work by acting as rRNA N-glycosylase (EC 3.2.2.22). They inactivate 60S ribosomal subunits by an N-glycosidic cleavage, which releases a specific adenine base from the sugar-phosphate backbone of 28S rRNA. RIPs exist in bacteria and plants. Members of the family include shiga toxins, and type I (e.g. trichosanthin and luffin) and type II (e.g. ricin, agglutinin, and abrin) ribosome inactivating proteins (RIPs). All these toxins are structurally related. RIPs have been of considerable interest because of their potential use, conjugated with monoclonal antibodies, as immunotoxins to treat cancers. Further, trichosanthin has been shown to have potent activity against HIV-1-infected T cells and macrophages. Elucidation of the structure-function relationships of RIPs has therefore become a major research effo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ricin
Ricin ( ) is a lectin (a carbohydrate-binding protein) and a highly potent toxin produced in the seeds of the castor oil plant, ''Ricinus communis''. The median lethal dose (LD50) of ricin for mice is around 22 micrograms per kilogram of body weight via intraperitoneal injection. Oral exposure to ricin is far less toxic. An estimated lethal oral dose in humans is approximately 1 milligram per kilogram of body weight. Ricin was first described by Peter Hermann Stillmark, the founder of lectinology. Biochemistry Ricin is classified as a type 2 ribosome-inactivating protein (RIP). Whereas type 1 RIPs are composed of a single protein chain that possesses catalytic activity, type 2 RIPs, also known as holotoxins, are composed of two different protein chains that form a heterodimeric complex. Type 2 RIPs consist of an A chain that is functionally equivalent to a type 1 RIP, covalently connected by a single disulfide bond to a B chain that is catalytically inactive, but serve ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Connecticut Agricultural Experiment Station
The Connecticut Agricultural Experiment Station (CAES) is the Connecticut state government's agricultural experiment station, a state government component that engages in scientific research and public outreach in agriculture and related fields. It is the oldest state experiment station in the United States, having been founded in 1875. Its official mission is to "develop, advance, and disseminate scientific knowledge, improve agricultural productivity and environmental quality, protect plants, and enhance human health and well-being through research for the benefit of Connecticut residents and the nation." The station operates a main research campus in New Haven, a research farm in Hamden, a satellite research facility and farm in Windsor, and a research farm in Griswold. The Storrs Agricultural Experiment Station is a separate agricultural research agency, founded in 1887 and part of the University of Connecticut, which also receives state and federal funding. Historic camp ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sterling Professor
Sterling Professor, the highest academic rank at Yale University, is awarded to a tenured faculty member considered the best in his or her field. It is akin to the rank of university professor at other universities. The appointment, made by the President of Yale University and confirmed by the Yale Corporation, can be granted to any Yale faculty member, and up to forty professors can hold the title at the same time. The position was established through a 1918 bequest from John William Sterling, and the first Sterling Professor was appointed in 1920. History The professorships are named for and funded by a $15-million bequest left by John W. Sterling John William Sterling (May 12, 1844 – July 5, 1918) was a founding partner of Shearman & Sterling LLP and major benefactor to Yale University. Early life and career John William Sterling was born in Stratford, Connecticut, the son of Cat ..., partner in the New York law firm Shearman & Sterling and an 1864 graduate o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Essential Amino Acids
An essential amino acid, or indispensable amino acid, is an amino acid that cannot be synthesized from scratch by the organism fast enough to supply its demand, and must therefore come from the diet. Of the 21 amino acids common to all life forms, the nine amino acids humans cannot synthesize are phenylalanine, valine, threonine, tryptophan, methionine, leucine, isoleucine, lysine, and histidine. Six other amino acids are considered conditionally essential in the human diet, meaning their synthesis can be limited under special pathophysiological conditions, such as prematurity in the infant or individuals in severe catabolic distress. These six are arginine, cysteine, glycine, glutamine, proline, and tyrosine. Six amino acids are non-essential (dispensable) in humans, meaning they can be synthesized in sufficient quantities in the body. These six are alanine, aspartic acid, asparagine, glutamic acid, serine, and selenocysteine (considered the 21st amino acid). Pyrrolysine (con ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Yale Graduate School
The Yale Graduate School of Arts and Sciences is the graduate school of Yale University. Founded in 1847, it is the oldest graduate school in North America, and was the first North American graduate school to confer a Doctor of Philosophy (Ph.D.) degree. The Graduate School is one of twelve constituent schools of Yale University and the only one that awards the degrees of Doctor of Philosophy, Master of Philosophy, Master of Arts, Master of Science, and Master of Engineering. While doctoral programs are also available in five of Yale's professional schools, students are enrolled through the graduate school, which confers their degrees. The school is administered in four divisions—Humanities, Social Sciences, and Biological and Physical Sciences—and its faculty are divided into 52 departments and programs. Nineteen of these programs terminate with the master's degree. The Graduate School enrolls approximately 2,800 students, one-third of whom come from outside the United St ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Yale School Of Medicine
The Yale School of Medicine is the graduate medical school at Yale University, a private research university in New Haven, Connecticut. It was founded in 1810 as the Medical Institution of Yale College and formally opened in 1813. The primary teaching hospital for the school is Yale New Haven Hospital. The school is home to the Harvey Cushing/John Hay Whitney Medical Library, one of the largest modern medical libraries which is known for its historical collections. The faculty includes 70 National Academy of Sciences members, 47 National Academy of Medicine members, and 13 Howard Hughes Medical Institute investigators. '' U.S. News & World Report'' currently ranks the Yale School of Medicine 10th in the country for research and 59th in primary care. The MD program is highly selective; for the class of 2022, the school received 4,968 applications to fill 104 seats. The median GPA for the class was 3.89, and the median MCAT was 521. Education The School of Medicine offers th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Physiological Chemistry
Biochemistry or biological chemistry is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology and metabolism. Over the last decades of the 20th century, biochemistry has become successful at explaining living processes through these three disciplines. Almost all areas of the life sciences are being uncovered and developed through biochemical methodology and research.Voet (2005), p. 3. Biochemistry focuses on understanding the chemical basis which allows biological molecules to give rise to the processes that occur within living cells and between cells, Karp (2009), p. 2. in turn relating greatly to the understanding of tissues and organs, as well as organism structure and function.Miller (2012). p. 62. Biochemistry is closely related to molecular biology, which is the study of the molecular mechanisms of biological phenomena.A ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hemp
Hemp, or industrial hemp, is a botanical class of '' Cannabis sativa'' cultivars grown specifically for industrial or medicinal use. It can be used to make a wide range of products. Along with bamboo, hemp is among the fastest growing plants on Earth. It was also one of the first plants to be spun into usable fiber 50,000 years ago. It can be refined into a variety of commercial items, including paper, rope, textiles, clothing, biodegradable plastics, paint, insulation, biofuel, food, and animal feed. Although chemotype I cannabis and hemp (types II, III, IV, V) are both ''Cannabis sativa'' and contain the psychoactive component tetrahydrocannabinol (THC), they represent distinct cultivar groups, typically with unique phytochemical compositions and uses. Hemp typically has lower concentrations of total THC and may have higher concentrations of cannabidiol (CBD), which potentially mitigates the psychoactive effects of THC. The legality of hemp varies widely among c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
