Kurt Henseleit
Kurt Henseleit (1907–1973) studied medicine in Berlin, where he was born, with final exams 1929 and was beginning in the winter semester 1930/31 a graduate student of and assistant to Hans Krebs in Freiburg im Breisgau, where he got his M.D. Between them they discovered the urea cycle (known also as the ''Krebs-Henseleit cycle''), and developed the Krebs-Henseleit solution. Later in life he was a physician (Facharzt) in Friedrichshafen Friedrichshafen ( or ; Low Alemannic: ''Hafe'' or ''Fridrichshafe'') is a city on the northern shoreline of Lake Constance (the ''Bodensee'') in Southern Germany, near the borders of both Switzerland and Austria. It is the district capital (''K .... References 1907 births 1973 deaths 20th-century German physicians {{biochemist-stub ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Urea Cycle
The urea cycle (also known as the ornithine cycle) is a cycle of biochemical reactions that produces urea (NH2)2CO from ammonia (NH3). Animals that use this cycle, mainly amphibians and mammals, are called ureotelic. The urea cycle converts highly toxic ammonia to urea for excretion. This cycle was the first metabolic cycle to be discovered by Hans Krebs and Kurt Henseleit in 1932, five years before the discovery of the TCA cycle. The urea cycle was described in more detail later on by Ratner and Cohen. The urea cycle takes place primarily in the liver and, to a lesser extent, in the kidneys. Function Amino acid catabolism results in waste ammonia. All animals need a way to excrete this product. Most aquatic organisms, or ammonotelic organisms, excrete ammonia without converting it. Organisms that cannot easily and safely remove nitrogen as ammonia convert it to a less toxic substance, such as urea, via the urea cycle, which occurs mainly in the liver. Urea produced by the li ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Krebs–Henseleit Solution
Krebs–Henseleit solution, developed by Hans Krebs and Kurt Henseleit, is a solution containing sodium (Na), potassium (K), chloride (Cl), calcium (Ca), magnesium sulfate (MgSO4), bicarbonate (HCO3), phosphate (PO4), glucose, and sometimes supplemented with albumin, and tromethamine (THAM). It has been used experimentally, for instance to study arteries ''ex vivo'', in Langendorff heart preparations, and during isolated muscle testing of mammalian skeletal muscles Skeletal muscle (commonly referred to as muscle) is one of the three types of vertebrate muscle tissue, the others being cardiac muscle and smooth muscle. They are part of the somatic nervous system, voluntary muscular system and typically are a .... References Solutions {{pharma-stub ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Hans Adolf Krebs
Sir Hans Adolf Krebs, FRS (, ; 25 August 1900 – 22 November 1981) was a German-British biologist, physician and biochemist. He was a pioneer scientist in the study of cellular respiration, a biochemical process in living cells that extracts energy from food and oxygen and makes it available to drive the processes of life. He is best known for his discoveries of two important sequences of chemical reactions that take place in the cells of nearly all organisms, including humans, other than anaerobic microorganisms, namely the citric acid cycle and the urea cycle. The former, often eponymously known as the "Krebs cycle", is the sequence of metabolic reactions that allows cells of oxygen-respiring organisms to obtain far more ATP from the food they consume than anaerobic processes such as glycolysis can supply; and its discovery earned Krebs a Nobel Prize in Physiology or Medicine in 1953. With Hans Kornberg, he also discovered the glyoxylate cycle, a slight variation of the ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Urea Cycle
The urea cycle (also known as the ornithine cycle) is a cycle of biochemical reactions that produces urea (NH2)2CO from ammonia (NH3). Animals that use this cycle, mainly amphibians and mammals, are called ureotelic. The urea cycle converts highly toxic ammonia to urea for excretion. This cycle was the first metabolic cycle to be discovered by Hans Krebs and Kurt Henseleit in 1932, five years before the discovery of the TCA cycle. The urea cycle was described in more detail later on by Ratner and Cohen. The urea cycle takes place primarily in the liver and, to a lesser extent, in the kidneys. Function Amino acid catabolism results in waste ammonia. All animals need a way to excrete this product. Most aquatic organisms, or ammonotelic organisms, excrete ammonia without converting it. Organisms that cannot easily and safely remove nitrogen as ammonia convert it to a less toxic substance, such as urea, via the urea cycle, which occurs mainly in the liver. Urea produced by the li ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Friedrichshafen
Friedrichshafen ( or ; Low Alemannic: ''Hafe'' or ''Fridrichshafe'') is a city on the northern shoreline of Lake Constance (the ''Bodensee'') in Southern Germany, near the borders of both Switzerland and Austria. It is the district capital (''Kreisstadt'') of the Bodensee district in the federal state of Baden-Württemberg. Friedrichshafen has a population of about 63,000. History 19th and early 20th century Friedrichshafen was established in 1811 as part of the new Kingdom of Württemberg, an ally of France during the Napoleonic Wars. It was named for King Frederick I of Württemberg, who privileged it as a free port and transshipment point for the kingdom's Swiss trade. Friedrichshafen was created from the former city of Buchhorn, whose coat of arms it adopted. The new city also incorporated the former village of Hofen, whose monastery was refurbished to serve as the summer residence of the Württemberger kings. King William I continued improving the city, including the ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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1907 Births
Events January * January 14 – 1907 Kingston earthquake: A 6.5 Mw earthquake in Kingston, Jamaica, kills between 800 and 1,000. February * February 9 – The " Mud March", the first large procession organised by The National Union of Women's Suffrage Societies ( NUWSS), takes place in London. * February 11 – The French warship ''Jean Bart'' sinks off the coast of Morocco. * February 12 – The steamship ''Larchmont'' collides with the ''Harry Hamilton'' in Long Island Sound; 183 lives are lost. * February 16 – SKF, a worldwide mechanical parts manufacturing brand (mainly, bearings and seals), is founded in Gothenburg, Sweden. * February 21 – The English mail steamship ''Berlin'' is wrecked off the Hook of Holland; 142 lives are lost. * February 24 – The Austrian Lloyd steamship ''Imperatrix'', from Trieste to Bombay, is wrecked on Cape of Crete and sinks; 137 lives are lost. March * March ** The steamship ''Congo'' collide ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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1973 Deaths
Events January * January 1 – The United Kingdom, the Republic of Ireland and Denmark 1973 enlargement of the European Communities, enter the European Economic Community, which later becomes the European Union. * January 14 - The 16-0 1972 Miami Dolphins season, Miami Dolphins defeated the 1972 Washington Redskins season, Washington Redskins in Super Bowl VII, with the Dolphins ending the season a perfect 17-0. This marked the first and only time that an NFL team has had a perfect undefeated season, an achievement the team holds to this day. * January 15 – Vietnam War: Citing progress in peace negotiations, U.S. President Richard Nixon announces the suspension of offensive action in North Vietnam. * January 17 – Ferdinand Marcos becomes President for Life of the Philippines. * January 22 ** ''Joe Frazier vs. George Foreman, The Sunshine Showdown'': George Foreman defeats Joe Frazier to win the heavyweight world boxing championship in Kingston, Jamaica. ** A Royal Jorda ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |