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Klimax
Estradiol valerate/prasterone enanthate (EV/DHEA-E), sold under the brand name Gynodian Depot among others, is an injectable combination medication of estradiol valerate (EV), an estrogen, and prasterone enanthate (-E), an androgen, estrogen, and neurosteroid, which is used in menopausal hormone therapy for women. It is provided in the form of 1 mL ampoules containing 4 mg estradiol valerate and 200 mg prasterone enanthate in an oil solution and is administered by intramuscular injection once every 4 to 6 weeks. EV/DHEA-E reportedly has a duration of about 21 days. The medication is available in Europe, Latin America, and Egypt. EV/DHEA-E was developed and marketed by Schering, was first described in the literature in 1972, and was introduced for medical use in April 1975. See also * List of combined sex-hormonal preparations This is a list of known combination drug, combined sex-hormonal agent, sex-hormonal pharmaceutical formulation, formulatio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Prasterone Enanthate
Prasterone enanthate, also known as dehydroepiandrosterone enanthate (DHEA-E) and sold in combination with estradiol valerate under the brand name Gynodian Depot among others, is a weak androgen, estrogen, and neurosteroid medication which is used as a component of menopausal hormone therapy to treat menopausal symptoms in women. It is available only as an injectable preparation in combination with estradiol valerate. The medication is given by injection into muscle typically once every 4 weeks. Prasterone enanthate is a synthetic androgen, estrogen, and neurosteroid. It is a steroid ester and a long-lasting prodrug of prasterone (dehydroepiandrosterone; DHEA) in the body. Prasterone is a naturally occurring prohormone of androgens and estrogens and hence is an agonist of the androgen and estrogen receptors, the respective biological targets of androgens like testosterone and estrogens like estradiol. Prasterone also has a variety of activities of its own, including ne ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
List Of Combined Sex-hormonal Preparations
This is a list of known combination drug, combined sex-hormonal agent, sex-hormonal pharmaceutical formulation, formulations. Brand names and developmental code names are in parentheses. Androgens Injection Marketed * Nandrolone decanoate/nandrolone phenylpropionate (Dinandrol) * Testosterone propionate/testosterone isocaproate/testosterone caproate (Androteston PP) * Testosterone propionate/testosterone enanthate/testosterone undecylenate (Durasteron) * Testosterone propionate/testosterone enanthate (Testoviron Depot) * Testosterone propionate/testosterone ketolaurate (Testosid Depot) * Testosterone propionate/testosterone phenylpropionate/testosterone isocaproate (Sustanon 100) * Testosterone propionate/testosterone phenylpropionate/testosterone isocaproate/testosterone caproate (Omnadren 250) * Testosterone propionate/testosterone phenylpropionate/testosterone isocaproate/testosterone decanoate (Sustanon 250) * Testosterone propionate/testosterone valerate/testosterone undecy ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Estradiol Valerate
Estradiol valerate (EV), sold for use oral administration, by mouth under the brand name Progynova and for use by injection (medicine), injection under the brand names Delestrogen and Progynon Depot among others, is an estrogen (medication), estrogen medication. It is used in menopausal hormone therapy, hormone therapy for menopausal symptoms and hypoestrogenism, low estrogen levels, transgender hormone therapy (male-to-female), hormone therapy for transgender people, and in hormonal contraception, hormonal birth control. It is also used in the treatment of prostate cancer. The medication is taken oral administration, by mouth or by intramuscular injection, injection into muscle or subcutaneous injection, fat once every 1 to 4 weeks. Side effects of estradiol valerate include breast tenderness, breast enlargement, nausea, headache, and water retention (medicine), fluid retention. Estradiol valerate is an estrogen (medication), estrogen and hence is an agonist of the estrog ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pharmacodynamics
Pharmacodynamics (PD) is the study of the biochemistry, biochemical and physiology, physiologic effects of drugs (especially pharmaceutical drugs). The effects can include those manifested within animals (including humans), microorganisms, or combinations of organisms (for example, infection). Pharmacodynamics and pharmacokinetics are the main branches of pharmacology, being itself a topic of biology interested in the study of the interactions of both endogenous and exogenous chemical substances with living organisms. In particular, pharmacodynamics is the study of how a drug affects an organism, whereas pharmacokinetics is the study of how the organism affects the drug. Both together influence dosing, benefit, and adverse effects. Pharmacodynamics is sometimes abbreviated as PD and pharmacokinetics as PK, especially in combined reference (for example, when speaking of PK/PD models). Pharmacodynamics places particular emphasis on dose–response relationships, that is, the relat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Estradiol And Dehydroepiandrosterone Levels After A Single Intramuscular Injection Of Gynodian Depot In Women
Estradiol (E2), also called oestrogen, oestradiol, is an estrogen steroid hormone and the major female sex hormone. It is involved in the regulation of female reproductive cycles such as estrous and menstrual cycles. Estradiol is responsible for the development of female secondary sexual characteristics such as the breasts, widening of the hips and a female pattern of fat distribution. It is also important in the development and maintenance of female reproductive tissues such as the mammary glands, uterus and vagina during puberty, adulthood and pregnancy. It also has important effects in many other tissues including bone, fat, skin, liver, and the brain. Though estradiol levels in males are much lower than in females, estradiol has important roles in males as well. Apart from humans and other mammals, estradiol is also found in most vertebrates and crustaceans, insects, fish, and other animal species. Estradiol is produced within the follicles of the ovaries and in other ti ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
