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Keith Burridge
Keith Burridge (born 1 July 1950) is a British researcher and Kenan distinguished Professor at the University of North Carolina at Chapel Hill.ISI Highly Cited ResearcheAn essay by: Professor Keith Burridgein-cites.com His research on focal adhesions includes the discovery of many adhesion proteins including vinculin, talin and paxillin, and ranks him in top 1% of the most cited scientist in the field of molecular biology and genetics. Burridge has published more than 200 peer reviewed articles. Early life and education He was born in 1950 in Dorset, England. He obtained his undergraduate degree in 1971 from the University of Cambridge, and then completed his PhD in Dennis Bray's laboratory in the MRC Laboratory of Molecular Biology (LMB), also in Cambridge, in 1975. Using biochemical techniques, he showed that at least two distinct types of myosin II exist in non-muscle cells and that some cells expressed both types. Focal adhesion research He went as a postdoc to James D. Wa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Keith Burridge Picture
Keith may refer to: People and fictional characters * Keith (given name), includes a list of people and fictional characters * Keith (surname) * Keith (singer), American singer James Keefer (born 1949) * Keith (gamer), American professional League of Legends player * Baron Keith, a line of Scottish barons in the late 18th century * Clan Keith, a Scottish clan associated with lands in northeastern and northwestern Scotland Places Australia * Keith, South Australia, a town and locality Scotland * Keith, Moray, a town ** Keith railway station * Keith Marischal, East Lothian United States * Keith, Georgia, an unincorporated community * Keith, Ohio, an unincorporated community * Keith, West Virginia, an unincorporated community * Keith, Wisconsin, a ghost town * Keith County, Nebraska Other uses * Keith F.C., a football team based in Keith, Scotland * , a ship of the British Royal Navy * Hurricane Keith, a 2000 hurricane that caused extensive damage in Central America * ''Ke ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Palladin
Palladin is a protein that in humans is encoded by the ''PALLD'' gene. Palladin is a component of actin-containing microfilaments that control cell shape, adhesion, and contraction. Discovery Palladin was characterised independently by two research groups, first in the lab of Carol Otey (in 2000) and then in the lab of Olli Carpén (in 2001). It is a part of the myotilin-myopalladin-palladin family and may play an important role in modulating the actin cytoskeleton. Palladin, in contrast to myotilin and myopalladin, which are expressed only in striated muscle, is expressed ubiquitously in cells of mesenchymal origin. Palladin was named after the Italian Renaissance architect Andrea Palladio, reflecting its localization to architectural elements of the cell. Isoforms In humans, it appears that seven different isoforms exist, some of which arise through alternative splicing. In mice, three major isoforms of palladin arise from a single gene. These isoforms contain between ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
British Expatriate Academics In The United States
British may refer to: Peoples, culture, and language * British people, nationals or natives of the United Kingdom, British Overseas Territories and Crown Dependencies. * British national identity, the characteristics of British people and culture * British English, the English language as spoken and written in United Kingdom of Great Britain and Northern Ireland and, more broadly, throughout the British Isles * Celtic Britons, an ancient ethno-linguistic group * Brittonic languages, a branch of the Insular Celtic language family (formerly called British) ** Common Brittonic, an ancient language Other uses *People or things associated with: ** Great Britain, an island ** British Isles, an island group ** United Kingdom, a sovereign state ** British Empire, a historical global colonial empire ** Kingdom of Great Britain (1707–1800) ** United Kingdom of Great Britain and Ireland (1801–1922) * British Raj, colonial India under the British Empire * British Hong Kong, colonial H ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Living People
Purpose: Because living persons may suffer personal harm from inappropriate information, we should watch their articles carefully. By adding an article to this category, it marks them with a notice about sources whenever someone tries to edit them, to remind them of WP:BLP (biographies of living persons) policy that these articles must maintain a neutral point of view, maintain factual accuracy, and be properly sourced. Recent changes to these articles are listed on Special:RecentChangesLinked/Living people. Organization: This category should not be sub-categorized. Entries are generally sorted by family name In many societies, a surname, family name, or last name is the mostly hereditary portion of one's personal name that indicates one's family. It is typically combined with a given name to form the full name of a person, although several give .... Maintenance: Individuals of advanced age (over 90), for whom there has been no new documentation in the last ten ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1950 Births
Events January * January 1 – The International Police Association (IPA) – the largest police organization in the world – is formed. * January 5 – 1950 Sverdlovsk plane crash, Sverdlovsk plane crash: ''Aeroflot'' Lisunov Li-2 crashes in a snowstorm. All 19 aboard are killed, including almost the entire national ice hockey team (VVS Moscow) of the Soviet Air Force – 11 players, as well as a team doctor and a masseur. * January 6 – The UK recognizes the People's Republic of China; the Republic of China severs diplomatic relations with Britain in response. * January 7 – A fire in the St Elizabeth's Ward of Mercy Hospital in Davenport, Iowa, United States, kills 41 patients. * January 9 – The Israeli government recognizes the People's Republic of China. * January 12 – Submarine collides with Sweden, Swedish oil tanker ''Divina'' in the Thames Estuary and sinks; 64 die. * January 13 – Finland forms diplomatic relations with the People's Republic of Chin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
UNC School Of Medicine
The University of North Carolina School of Medicine is the medical school of the University of North Carolina at Chapel Hill. It offers a Doctor of Medicine degree, along with combined Doctor of Medicine with Doctor of Philosophy degree and Doctor of Medicine with Master of Public Health degree program. It is one of the top-ranked medical schools in the country: in 2022, ''U.S. News & World Report'' ranked the school 5th in primary care and 25th in research. In 2016, the school received $449 million in research funding. With approximately two-thirds of that amount coming from the National Institutes of Health, the school received more federal research funding than any other public or private university in the South.FY 2016 Research Funding June 20, 2017. Curriculum As of fall 2014, UNC ...[...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Woodrow Wilson
Thomas Woodrow Wilson (December 28, 1856February 3, 1924) was the 28th president of the United States, serving from 1913 to 1921. He was the only History of the Democratic Party (United States), Democrat to serve as president during the Progressive Era when Republicans dominated the presidency and United States Congress, legislative branches. As president, Wilson changed the nation's economic policies and led the United States into World War I. He was the leading architect of the League of Nations, and his stance on foreign policy came to be known as Wilsonianism. Born in Staunton, Virginia, Wilson early life of Woodrow Wilson, grew up in the Southern United States during the American Civil War and Reconstruction era. After earning a Doctor of Philosophy, Ph.D. in history and political science from Johns Hopkins University, Wilson taught at several colleges prior to being appointed president of Princeton University, where he emerged as a prominent spokesman for progressivism ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Edith Wilson
Edith Wilson ( Bolling, formerly Galt; October 15, 1872 – December 28, 1961) was First Lady of the United States from 1915 to 1921 as the second wife of President Woodrow Wilson. She married the widower Wilson in December 1915, during his first term as president. Edith Wilson played an influential role in Presidency of Woodrow Wilson, President Wilson's administration following the severe stroke he suffered in October 1919. For the remainder of her husband's presidency, she managed the office of the president, a role she later described as a "stewardship", and determined which communications and matters of state were important enough to bring to the attention of the bedridden president. Early life and education Edith Bolling was born October 15, 1872, in Wytheville, Virginia, to circuit court judge William Holcombe Bolling and his wife Sarah "Sallie" Spears (née White). Her birthplace, the Bolling Home, is now a museum located in Wytheville Historic District, Wytheville's Hist ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Han Van Meegeren
Henricus Antonius "Han" van Meegeren (; 10 October 1889 – 30 December 1947) was a Dutch painter and portraitist, considered one of the most ingenious Art forgery, art forgers of the 20th century. Van Meegeren became a national hero after World War II when it was revealed that he had sold a forged painting to ''Reichsmarschall'' Hermann Göring during the Nazi occupation of the Netherlands. Van Meegeren attempted to make a career as an artist, but art critics dismissed his work. He decided to prove his talent by forging paintings from the Dutch Golden Age painting, Dutch Golden Age. Leading experts of the time accepted his paintings as genuine 17th-century works, including art collector Abraham Bredius. During World War II, Göring purchased one of Van Meegeren's "Johannes Vermeer, Vermeers", which became one of his most prized possessions. Following the war, Van Meegeren was arrested on a charge of selling cultural property to the Nazis. Facing a possible death penalty, he con ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Knutsford Little Theatre
Knutsford Little Theatre is an amateur theatre group based in Knutsford, United Kingdom. They were formed in 1925, as ''Knutsford Amateur Drama Society'' and changed their name, after acquiring their own premises on Queen Street. They perform up to seven productions a year including a very popular family pantomime and a youth production. The society is run by its members who are entitled to vote at the annual award ceremony held as part of the AGM. The Society is part of the Cheshire Theatre Guild, and the National Operatic and Dramatic Association. History The society was formed after a meeting in the Cranford Cafe on a date in March 1925 when a group of local residents met to discuss the formation of Knutsford Amateur Dramatic Society. There had been theatrical productions in Knutsford for a number of years prior to the meeting: the Y.M.C.A. had performed Thread of Scarlett, a play about a murder in Ashley that resulted in execution at Knutsford Prison, and the Young Liberal ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
RhoA
Transforming protein RhoA, also known as Ras homolog family member A (RhoA), is a small GTPase protein in the Rho family of GTPases that in humans is encoded by the ''RHOA'' gene. While the effects of RhoA activity are not all well known, it is primarily associated with cytoskeleton regulation, mostly actin stress fibers formation and actomyosin contractility. It acts upon several effectors. Among them, ROCK1 (Rho-associated, coiled-coil containing protein kinase 1) and DIAPH1 (Diaphanous Homologue 1, a.k.a. hDia1, homologue to mDia1 in mouse, diaphanous in ''Drosophila'') are the best described. RhoA, and the other Rho GTPases, are part of a larger family of related proteins known as the Ras superfamily, a family of proteins involved in the regulation and timing of cell division. RhoA is one of the oldest Rho GTPases, with homologues present in the genomes since 1.5 billion years. As a consequence, RhoA is somehow involved in many cellular processes which emerged throughout ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Zyxin
ZYX is a protein that in humans is encoded by the ''ZYX'' gene. Function Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domain LIM domains are protein structural domains, composed of two contiguous zinc fingers, separated by a two-amino acid residue hydrophobic linker. The domain name is an acronym of the three genes in which it was first identified (LIN-11, Isl-1 and M ...s in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
