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KE Family
The KE family is a medical name designated for a British family, about half of whom exhibit a severe speech disorder called developmental verbal dyspraxia. It is the first family with speech disorder to be investigated using genetic analyses, by which the speech impairment is discovered to be due to genetic mutation, and from which the gene ''FOXP2'', often dubbed the "language gene", was discovered. Their condition is also the first human speech and language disorder known to exhibit strict Mendelian inheritance. Brought to medical attention from their school children in the late 1980s, the case of KE family was taken up at the UCL Institute of Child Health in London in 1990. Initial report suggested that the family was affected by a genetic disorder. Canadian linguist Myrna Gopnik suggested that the disorder was characterized primarily by grammatical deficiency, supporting the controversial notion of a "grammar gene". Geneticists at the University of Oxford determined that the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
British People
British people or Britons, also known colloquially as Brits, are the citizens of the United Kingdom, the British Overseas Territories, and the Crown dependencies.: British nationality law governs modern British citizenship and nationality, which can be acquired, for instance, by descent from British nationals. When used in a historical context, "British" or "Britons" can refer to the Ancient Britons, the Celtic languages, Celtic-speaking inhabitants of Great Britain during the British Iron Age, Iron Age, whose descendants formed the major part of the modern Welsh people, Cornish people, Bretons and considerable proportions of English people. It also refers to those British subjects born in parts of the former British Empire that are now independent countries who settled in the United Kingdom prior to 1973. Though early assertions of being British date from the Late Middle Ages, the Union of the Crowns in 1603 and the creation of the Kingdom of Great Britain in 1707 triggered ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Documentary Film
A documentary film (often described simply as a documentary) is a nonfiction Film, motion picture intended to "document reality, primarily for instruction, education or maintaining a Recorded history, historical record". The American author and Media studies, media analyst Bill Nichols (film critic), Bill Nichols has characterized the documentary in terms of "a filmmaking practice, a cinematic tradition, and mode of audience reception [that remains] a practice without clear boundaries". Research into information gathering, as a behavior, and the sharing of knowledge, as a concept, has noted how documentary movies were preceded by the notable practice of documentary photography. This has involved the use of singular Photograph, photographs to detail the complex attributes of History, historical events and continues to a certain degree to this day, with an example being the War photography, conflict-related photography achieved by popular figures such as Mathew Brady during the Am ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Montreal, Quebec
Montreal is the List of towns in Quebec, largest city in the Provinces and territories of Canada, province of Quebec, the List of the largest municipalities in Canada by population, second-largest in Canada, and the List of North American cities by population, ninth-largest in North America. It was founded in 1642 as ''Fort Ville-Marie, Ville-Marie'', or "City of Mary", and is now named after Mount Royal, the triple-peaked mountain around which the early settlement was built. The city is centred on the Island of Montreal and a few, much smaller, peripheral islands, the largest of which is Île Bizard. The city is east of the national capital, Ottawa, and southwest of the provincial capital, Quebec City. the city had a population of 1,762,949, and a Census geographic units of Canada#Census metropolitan areas, metropolitan population of 4,291,732, making it the List of census metropolitan areas and agglomerations in Canada, second-largest metropolitan area in Canada. French l ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
McGill University
McGill University (French: Université McGill) is an English-language public research university in Montreal, Quebec, Canada. Founded in 1821 by royal charter,Frost, Stanley Brice. ''McGill University, Vol. I. For the Advancement of Learning, 1801–1895.'' McGill-Queen's University Press, 1980. the university bears the name of James McGill, a Scottish merchant, whose bequest in 1813 established the University of McGill College. In 1885, the name of the university was officially changed to McGill University. Its main campus is on the slope of Mount Royal in downtown Montreal in the borough of Ville-Marie, with a second campus situated in Sainte-Anne-de-Bellevue, west of the main campus on Montreal Island. The university is one of two members of the Association of American Universities located outside the United States, alongside the University of Toronto, and is the only Canadian member of the Global University Leaders Forum (GULF) within the World Economic Forum. The ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Autosomal Dominant
In genetics, dominance is the phenomenon of one variant (allele) of a gene on a chromosome masking or overriding the Phenotype, effect of a different variant of the same gene on Homologous chromosome, the other copy of the chromosome. The first variant is termed dominant and the second is called recessive. This state of having Heterozygosity, two different variants of the same gene on each chromosome is originally caused by a mutation in one of the genes, either new (''de novo'') or Heredity, inherited. The terms autosomal dominant or autosomal recessive are used to describe gene variants on non-sex chromosomes (autosomes) and their associated traits, while those on sex chromosomes (allosomes) are termed X-linked dominant, X-linked recessive or Y-linked; these have an inheritance and presentation pattern that depends on the sex of both the parent and the child (see Sex linkage). Since there is only one Y chromosome, Y-linked traits cannot be dominant or recessive. Additionally, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Great Ormond Street Hospital
Great Ormond Street Hospital (informally GOSH, formerly the Hospital for Sick Children) is a children's hospital located in the Bloomsbury area of the London Borough of Camden, and a part of Great Ormond Street Hospital for Children NHS Foundation Trust. The hospital is the largest centre for child heart surgery in Britain and one of the largest centres for heart transplantation in the world. In 1962 it developed the first heart and lung bypass machine for children. With children's book author Roald Dahl, it developed an improved shunt valve for children with hydrocephalus, and non-invasive (percutaneous) heart valve replacements. Great Ormond Street performed the first UK clinical trials of the rubella vaccine, and the first bone marrow transplant and gene therapy for severe combined immunodeficiency.Breakthroughs The hospital is the largest centre for research and postgraduate teaching in children's health in Europe. In 1929, J. M. Barrie donated the copyright ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Max Planck Institute For Psycholinguistics
The Max Planck Institute for Psycholinguistics (German: ''Max-Planck-Institut für Psycholinguistik''; Dutch: ''Max Planck Instituut voor Psycholinguïstiek'') is a research institute located on the campus of Radboud University Nijmegen in Nijmegen, Gelderland, the Netherlands. The institute was founded in 1980 by Dutch psycholinguist Pim Levelt and is dedicated exclusively to psycholinguistics. It is one of the few institutes of the Max Planck Society situated outside Germany. According to the ranking of Web of World Research Centers, the institute ranks second amongst all Max Planck Institutes (MPI) in terms of visibility and eighth in terms of size. Research The institute specializes in language comprehension, language production, language acquisition, language and genetics, and the relation between language and cognition. Its mission is to undertake basic research into the psychological, social, and biological foundations of language. The goal is to understand how human min ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Simon E
Simon may refer to: People * Simon (given name), including a list of people and fictional characters with the given name Simon * Simon (surname), including a list of people with the surname Simon * Eugène Simon, French naturalist and the genus authority ''Simon'' * Tribe of Simeon, one of the twelve tribes of Israel Places * Şimon (), a village in Bran Commune, Braşov County, Romania * Șimon, a right tributary of the river Turcu in Romania Arts, entertainment, and media Films * ''Simon'' (1980 film), starring Alan Arkin * ''Simon'' (2004 film), Dutch drama directed by Eddy Terstall * ''Simón'' (2018 film), Venezuelan short film directed by Diego Vicentini * ''Simón'' (2023 film), Venezuelan feature film directed by Diego Vicentini Games * ''Simon'' (game), a popular computer game * Simon Says, children's game Literature * ''Simon'' (Sutcliff novel), a children's historical novel written by Rosemary Sutcliff * Simon (Sand novel), an 1835 novel by George Sand * ' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Leipzig University
Leipzig University (), in Leipzig in Saxony, Germany, is one of the world's oldest universities and the second-oldest university (by consecutive years of existence) in Germany. The university was founded on 2 December 1409 by Frederick I, Elector of Saxony and his brother William II, Margrave of Meissen, and originally comprised the four scholastic faculties. Since its inception, the university has engaged in teaching and research for over 600 years without interruption. Famous alumni include Angela Merkel, Gottfried Wilhelm von Leibniz, Johann Wolfgang von Goethe, Leopold von Ranke, Friedrich Nietzsche, Robert Schumann, Richard Wagner, Tycho Brahe, Georgius Agricola. The university is associated with ten Nobel laureates, most recently with Svante Pääbo who won the Nobel Prize for Medicine in 2022. History Founding and development until 1900 The university was modelled on the University of Prague, from which the German-speaking faculty members withdrew to Leipzig ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Developmental Disorders
Developmental disorders comprise a group of psychiatric conditions originating in childhood that involve serious impairment in different areas. There are several ways of using this term. The most narrow concept is used in the category "Specific Disorders of Psychological Development" in the ICD-10. These disorders comprise developmental language disorder, learning disorders, developmental coordination disorders, and autism spectrum disorders (ASD). In broader definitions, attention deficit hyperactivity disorder (ADHD) is included, and the term used is neurodevelopmental disorders. Yet others include antisocial behavior and schizophrenia that begins in childhood and continues through life. However, these two latter conditions are not as stable as the other developmental disorders, and there is not the same evidence of a shared genetic liability. Developmental disorders are present from early life onward. Most improve as the child grows older, but some entail impairments tha ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Yale University
Yale University is a Private university, private Ivy League research university in New Haven, Connecticut, United States. Founded in 1701, Yale is the List of Colonial Colleges, third-oldest institution of higher education in the United States, and one of the nine colonial colleges chartered before the American Revolution. Yale was established as the Collegiate School in 1701 by Congregationalism in the United States, Congregationalist clergy of the Connecticut Colony. Originally restricted to instructing ministers in theology and sacred languages, the school's curriculum expanded, incorporating humanities and sciences by the time of the American Revolution. In the 19th century, the college expanded into graduate and professional instruction, awarding the first Doctor of Philosophy, PhD in the United States in 1861 and organizing as a university in 1887. Yale's faculty and student populations grew rapidly after 1890 due to the expansion of the physical campus and its scientif ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Elena L
Elena may refer to: People * Elena (given name), including a list of people and characters with this name * Raymond Elena (1931-2024), French former professional racing cyclist. * Joan Ignasi Elena (born 1968), Catalan politician * Francine Elena (born 1986), British poet Geography * Elena (town), a town in Veliko Tarnovo Province, Bulgaria ** Elena Municipality * Elena (village), a village in Haskovo Province Film and television * Elena (2011 film), ''Elena'' (2011 film), a 2011 Russian film * Elena (2012 film), ''Elena'' (2012 film), a Brazilian film * Elena (TV series), ''Elena'' (TV series), a Mexican telenovela * ''Elena of Avalor'', an American TV series * ''Daniele Cortis'', a 1947 Italian film also known as ''Elena'' Music * Elena (Cavalli), ''Elena'' (Cavalli), a 1659 opera by Francesco Cavalli * Elena (Mayr), ''Elena'' (Mayr), an 1814 opera by Mayr * Elena (song), "Elena" (song), a 1979 song by The Marc Tanner Band * ''Elena'', an EP by Puerto Muerto Other * Elena (pl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
