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June Lindsey
June Monica Lindsey ( Broomhead, June 7, 1922 – November 4, 2021) was a British-Canadian physical chemist. Whilst working on X-ray crystallography at the University of Cambridge, Lindsey was influential in the elucidation of the structure of DNA. She solved the structures of the purines, adenine and guanine. Her depiction of intramolecular hydrogen bonds in adenine crystals was central to Watson and Crick's elucidation of the double helical structure of DNA. Education and early career June Broomhead was born in Doncaster, England in June 1922. She joined the University of Cambridge, UK, in 1941. She completed the requirements for her degree in 1944, and joined the Cavendish Laboratory at the University of Cambridge. World War II forced her to leave her research career, however. She was encouraged to become a teacher and spent two years teaching science in a school. She returned to Cambridge in 1946. She completed her undergraduate courses in 1944 at Newnham College, but Cam ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Cambridge
The University of Cambridge is a Public university, public collegiate university, collegiate research university in Cambridge, England. Founded in 1209, the University of Cambridge is the List of oldest universities in continuous operation, world's third-oldest university in continuous operation. The university's founding followed the arrival of scholars who left the University of Oxford for Cambridge after a dispute with local townspeople. The two ancient university, ancient English universities, although sometimes described as rivals, share many common features and are often jointly referred to as Oxbridge. In 1231, 22 years after its founding, the university was recognised with a royal charter, granted by Henry III of England, King Henry III. The University of Cambridge includes colleges of the University of Cambridge, 31 semi-autonomous constituent colleges and List of institutions of the University of Cambridge#Schools, Faculties, and Departments, over 150 academic departm ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Newnham College, Cambridge
Newnham College is a women's constituent college of the University of Cambridge. The college was founded in 1871 by a group organising Lectures for Ladies, members of which included philosopher Henry Sidgwick and suffragist campaigner Millicent Garrett Fawcett. It was the second women's college to be founded at Cambridge, following Girton College. The College celebrated its 150th anniversary throughout 2021 and 2022. History The history of Newnham begins with the formation of the Association for Promoting the Higher Education of Women in Cambridge in 1869. The progress of women at Cambridge University owes much to the pioneering work undertaken by the philosopher Henry Sidgwick, fellow of Trinity. Lectures for Ladies had been started in Cambridge in 1869,Stefan Collini, "Sidgwick, Henry (1838–1900)", ''Oxford Dictionary of National Biography'', Oxford University Press, 2004; online edn, May 2007Retrieved 4 January 2017/ref> and such was the demand from those who could not tr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Crystallography
Crystallography is the branch of science devoted to the study of molecular and crystalline structure and properties. The word ''crystallography'' is derived from the Ancient Greek word (; "clear ice, rock-crystal"), and (; "to write"). In July 2012, the United Nations recognised the importance of the science of crystallography by proclaiming 2014 the International Year of Crystallography.UN announcement "International Year of Crystallography" iycr2014.org. 12 July 2012 Crystallography is a broad topic, and many of its subareas, such as X-ray crystallography, are themselves important scientific topics. Crystallography ranges from the fundamentals of crystal structure to the mathematics of Crystal system, crystal geometry, including those that are Aperiodic crystal, not periodic or quasi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Montreal
Montreal is the List of towns in Quebec, largest city in the Provinces and territories of Canada, province of Quebec, the List of the largest municipalities in Canada by population, second-largest in Canada, and the List of North American cities by population, ninth-largest in North America. It was founded in 1642 as ''Fort Ville-Marie, Ville-Marie'', or "City of Mary", and is now named after Mount Royal, the triple-peaked mountain around which the early settlement was built. The city is centred on the Island of Montreal and a few, much smaller, peripheral islands, the largest of which is Île Bizard. The city is east of the national capital, Ottawa, and southwest of the provincial capital, Quebec City. the city had a population of 1,762,949, and a Census geographic units of Canada#Census metropolitan areas, metropolitan population of 4,291,732, making it the List of census metropolitan areas and agglomerations in Canada, second-largest metropolitan area in Canada. French l ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Morphine
Morphine, formerly also called morphia, is an opiate that is found naturally in opium, a dark brown resin produced by drying the latex of opium poppies (''Papaver somniferum''). It is mainly used as an analgesic (pain medication). There are multiple methods used to administer morphine: oral; sublingual administration, sublingual; via inhalation; intramuscular, injection into a muscle, Subcutaneous injection, injection under the skin, or injection into the spinal cord area; transdermal; or via rectal administration, rectal suppository. It acts directly on the central nervous system (CNS) to induce analgesia and alter perception and emotional response to pain. Physical and psychological dependence and tolerance may develop with repeated administration. It can be taken for both acute pain and chronic pain and is frequently used for pain from myocardial infarction, kidney stones, and during Childbirth, labor. Its maximum effect is reached after about 20 minutes when administ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Codeine
Codeine is an opiate and prodrug of morphine mainly used to treat pain, coughing, and diarrhea. It is also commonly used as a recreational drug. It is found naturally in the sap of the opium poppy, ''Papaver somniferum''. It is typically used to treat mild to moderate degrees of pain. Greater benefit may occur when combined with paracetamol (acetaminophen) or a nonsteroidal anti-inflammatory drug (NSAID) such as aspirin or ibuprofen. Evidence does not support its use for acute cough suppression in children. In Europe, it is not recommended as a cough medicine for those under 12 years of age. It is generally taken by mouth. It typically starts working after half an hour, with maximum effect at two hours. Its effects last for about four to six hours. Codeine exhibits abuse potential similar to other opioid medications, including a risk of addiction and overdose. Common side effects include nausea, vomiting, constipation, itchiness, lightheadedness, and drowsiness. Serious ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Research Council Canada
The National Research Council Canada (NRC; ) is the primary national agency of the Government of Canada dedicated to science and technology research and development. It is the largest federal research and development organization in Canada. The Minister of Innovation, Science, and Economic Development is responsible for the NRC. Mandate NRC is an agency of the Government of Canada, and its mandate is set out in the '' National Research Council Act''. Under the Act, the NRC is responsible for: * Undertaking, assisting or promoting scientific and industrial research in fields of importance to Canada; * Providing vital scientific and technological services to the research and industrial communities; * Investigating standards and methods of measurement; * Working on the standardization and certification of scientific and technical apparatus, instruments and materials used or usable by Canadian industry; * Operating and administering any astronomical observatories established o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lawrence Bragg
Sir William Lawrence Bragg (31 March 1890 – 1 July 1971) was an Australian-born British physicist who shared the 1915 Nobel Prize in Physics with his father William Henry Bragg "for their services in the analysis of crystal structure by means of X-rays", an important step in the development of X-ray crystallography. As of 2024, he is the youngest ever List of Nobel laureates, Nobel laureate in physics, or in any science category, having received the award at the age of 25. Bragg was the director of the Cavendish Laboratory, Cambridge, when James D. Watson and Francis Crick reported the discovery of the structure of DNA in February 1953. Education and early life Bragg was born in Adelaide, South Australia to William Henry Bragg (1862–1942), Thomas Elder, Elder Professor of Mathematics and Physics at the University of Adelaide, and Gwendoline (1869–1929), daughter of Charles Todd (pioneer), Charles Todd, government astronomer of South Australia. In 1900, Bragg was a st ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Canada
Canada is a country in North America. Its Provinces and territories of Canada, ten provinces and three territories extend from the Atlantic Ocean to the Pacific Ocean and northward into the Arctic Ocean, making it the world's List of countries and dependencies by area, second-largest country by total area, with the List of countries by length of coastline, world's longest coastline. Its Canada–United States border, border with the United States is the world's longest international land border. The country is characterized by a wide range of both Temperature in Canada, meteorologic and Geography of Canada, geological regions. With Population of Canada, a population of over 41million people, it has widely varying population densities, with the majority residing in List of the largest population centres in Canada, urban areas and large areas of the country being sparsely populated. Canada's capital is Ottawa and List of census metropolitan areas and agglomerations in Canada, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vitamin B12
Vitamin B12, also known as cobalamin, is a water-soluble vitamin involved in metabolism. One of eight B vitamins, it serves as a vital cofactor (biochemistry), cofactor in DNA synthesis and both fatty acid metabolism, fatty acid and amino acid metabolism. It plays an essential role in the nervous system by supporting myelinogenesis, myelin synthesis and is critical for the maturation of red blood cells in the bone marrow. While animals require B12, plants do not, relying instead on alternative enzymatic pathways. Vitamin B12 is the most chemically complex of all vitamins, and is synthesized exclusively by certain archaea and bacteria. Natural food sources include meat, shellfish, liver, fish, poultry, Egg as food, eggs, and dairy products. It is also added to many breakfast cereals through food fortification and is available in dietary supplement and pharmaceutical forms. Supplements are commonly taken orally but may be administered via intramuscular injection to treat defic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dorothy Hodgkin
Dorothy Mary Crowfoot Hodgkin (née Crowfoot; 12 May 1910 – 29 July 1994) was a Nobel Prize-winning English chemist who advanced the technique of X-ray crystallography to determine the structure of biomolecules, which became essential for structural biology. Among her most influential discoveries are the confirmation of the structure of penicillin as previously surmised by Edward Abraham and Ernst Boris Chain; and mapping the structure of vitamin B12, vitamin B12, for which in 1964 she became the third woman to win the Nobel Prize in Chemistry. Hodgkin also elucidated the structure of insulin in 1969 after 35 years of work. Hodgkin used the name "Dorothy Crowfoot" until twelve years after marrying Thomas Lionel Hodgkin, when she began using "Dorothy Crowfoot Hodgkin". Hodgkin is referred to as "Dorothy Hodgkin" by the Royal Society (when referring to its sponsorship of the Dorothy Hodgkin fellowship), and by Somerville College. The National Archives (United Kingdom), The ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Watson And Crick
"Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid" was the first article published to describe the discovery of the double helix structure of DNA, using X-ray diffraction and the mathematics of a helix transform. It was published by Francis Crick and James D. Watson in the scientific journal ''Nature'' on pages 737–738 of its 171st volume (dated 25 April 1953). This article is often termed a "pearl" of science because it is brief and contains the answer to a fundamental mystery about living organisms. This mystery was the question of how it is possible that genetic instructions are held inside organisms and how they are passed from generation to generation. The article presents a simple and elegant solution, which surprised many biologists at the time who believed that DNA transmission was going to be more difficult to deduce and understand. The discovery had a major impact on biology, particularly in the field of genetics, enabling later ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
