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June Lindsey
June Monica Lindsey ( Broomhead, June 7, 1922 – November 4, 2021) was a British-Canadian physical chemist. Whilst working on X-ray crystallography at the University of Cambridge, Lindsey was influential in the elucidation of the structure of DNA. She solved the structures of the purines, adenine and guanine. Her depiction of intramolecular hydrogen bonds in adenine crystals was central to James Watson, Watson and Francis Crick, Crick's Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid, elucidation of the double helical structure of DNA. Education and early career June Broomhead was born in Doncaster, England in June 1922. She joined the University of Cambridge, UK, in 1941. She completed her degree in 1944, and joined the Cavendish Laboratory at the University of Cambridge. World War II forced her to leave her research career, however. She was encouraged to become a teacher and spent two years teaching science in a school. She returned to Cambridge i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Cambridge
, mottoeng = Literal: From here, light and sacred draughts. Non literal: From this place, we gain enlightenment and precious knowledge. , established = , other_name = The Chancellor, Masters and Scholars of the University of Cambridge , type = Public research university , endowment = £7.121 billion (including colleges) , budget = £2.308 billion (excluding colleges) , chancellor = The Lord Sainsbury of Turville , vice_chancellor = Anthony Freeling , students = 24,450 (2020) , undergrad = 12,850 (2020) , postgrad = 11,600 (2020) , city = Cambridge , country = England , campus_type = , sporting_affiliations = The Sporting Blue , colours = Cambridge Blue , website = , logo = University of Cambridge log ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
World War II
World War II or the Second World War, often abbreviated as WWII or WW2, was a world war that lasted from 1939 to 1945. It involved the World War II by country, vast majority of the world's countries—including all of the great powers—forming two opposing military alliances: the Allies of World War II, Allies and the Axis powers. World War II was a total war that directly involved more than 100 million Military personnel, personnel from more than 30 countries. The major participants in the war threw their entire economic, industrial, and scientific capabilities behind the war effort, blurring the distinction between civilian and military resources. Air warfare of World War II, Aircraft played a major role in the conflict, enabling the strategic bombing of population centres and deploying the Atomic bombings of Hiroshima and Nagasaki, only two nuclear weapons ever used in war. World War II was by far the List of wars by death toll, deadliest conflict in hu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Crystallography
Crystallography is the experimental science of determining the arrangement of atoms in crystalline solids. Crystallography is a fundamental subject in the fields of materials science and solid-state physics (condensed matter physics). The word "crystallography" is derived from the Greek word κρύσταλλος (''krystallos'') "clear ice, rock-crystal", with its meaning extending to all solids with some degree of transparency, and γράφειν (''graphein'') "to write". In July 2012, the United Nations recognised the importance of the science of crystallography by proclaiming that 2014 would be the International Year of Crystallography. denote a direction vector (in real space). * Coordinates in ''angle brackets'' or ''chevrons'' such as <100> denote a ''family'' of directions which are related by symmetry operations. In the cubic crystal system for example, would mean 00 10 01/nowiki> or the negative of any of those directions. * Miller indices in ''parentheses ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Montreal
Montreal ( ; officially Montréal, ) is the second-most populous city in Canada and most populous city in the Canadian province of Quebec. Founded in 1642 as '' Ville-Marie'', or "City of Mary", it is named after Mount Royal, the triple-peaked hill around which the early city of Ville-Marie is built. The city is centred on the Island of Montreal, which obtained its name from the same origin as the city, and a few much smaller peripheral islands, the largest of which is Île Bizard. The city is east of the national capital Ottawa, and southwest of the provincial capital, Quebec City. As of 2021, the city had a population of 1,762,949, and a metropolitan population of 4,291,732, making it the second-largest city, and second-largest metropolitan area in Canada. French is the city's official language. In 2021, it was spoken at home by 59.1% of the population and 69.2% in the Montreal Census Metropolitan Area. Overall, 85.7% of the population of the city of Montreal co ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Morphine
Morphine is a strong opiate that is found naturally in opium, a dark brown resin in poppies ('' Papaver somniferum''). It is mainly used as a pain medication, and is also commonly used recreationally, or to make other illicit opioids. There are numerous methods used to administer morphine: oral; sublingual; via inhalation; injection into a muscle; by injection under the skin; intravenously; injection into the space around the spinal cord; transdermal; or via rectal suppository. It acts directly on the central nervous system (CNS) to induce analgesia and alter perception and emotional response to pain. Physical and psychological dependence and tolerance may develop with repeated administration. It can be taken for both acute pain and chronic pain and is frequently used for pain from myocardial infarction, kidney stones, and during labor. Its maximum effect is reached after about 20 minutes when administered intravenously and 60 minutes when administered ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Codeine
Codeine is an opiate and prodrug of morphine mainly used to treat pain, coughing, and diarrhea. It is also commonly used as a recreational drug. It is found naturally in the sap of the opium poppy, ''Papaver somniferum''. It is typically used to treat mild to moderate degrees of pain. Greater benefit may occur when combined with paracetamol (acetaminophen) or a nonsteroidal anti-inflammatory drug (NSAID) such as aspirin or ibuprofen. Evidence does not support its use for acute cough suppression in children or adults. In Europe, it is not recommended as a cough medicine in those under 12 years of age. It is generally taken by mouth. It typically starts working after half an hour, with maximum effect at two hours. Its effects last for about four to six hours. Codeine exhibits abuse potential similar to other opioid medications. Common side effects include vomiting, constipation, itchiness, lightheadedness, and drowsiness. Serious side effects may include breathing difficult ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Research Council Canada
The National Research Council Canada (NRC; french: Conseil national de recherches Canada) is the primary national agency of the Government of Canada dedicated to science and technology research & development. It is the largest federal research & development organization in Canada. The Minister of Innovation, Science, and Economic Development (currently, François-Philippe Champagne) is responsible for the NRC. Mandate NRC is an agency of the Government of Canada, and its mandate is set out in the ''National Research Council Act''. Under the Act, the NRC is responsible for: * Undertaking, assisting or promoting scientific and industrial research in fields of importance to Canada; * Providing vital scientific and technological services to the research and industrial communities; * Investigating standards and methods of measurement; * Working on the standardization and certification of scientific and technical apparatus, instruments and materials used or usable by Canadian i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lawrence Bragg
Sir William Lawrence Bragg, (31 March 1890 – 1 July 1971) was an Australian-born British physicist and X-ray crystallographer, discoverer (1912) of Bragg's law of X-ray diffraction, which is basic for the determination of crystal structure. He was joint recipient (with his father, William Henry Bragg) of the Nobel Prize in Physics in 1915, "For their services in the analysis of crystal structure by means of X-rays"; an important step in the development of X-ray crystallography. Bragg was knighted in 1941. As of 2021, he is the youngest ever Nobel laureate in physics, having received the award at the age of 25 years. Bragg was the director of the Cavendish Laboratory, Cambridge, when the discovery of the structure of DNA was reported by James D. Watson and Francis Crick in February 1953. Biography Early years Bragg was born in Adelaide, South Australia to Sir William Henry Bragg (1862–1942), Elder Professor of Mathematics and Physics at the University of Adelaide, and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Canada
Canada is a country in North America. Its ten provinces and three territories extend from the Atlantic Ocean to the Pacific Ocean and northward into the Arctic Ocean, covering over , making it the world's second-largest country by total area. Its southern and western border with the United States, stretching , is the world's longest binational land border. Canada's capital is Ottawa, and its three largest metropolitan areas are Toronto, Montreal, and Vancouver. Indigenous peoples have continuously inhabited what is now Canada for thousands of years. Beginning in the 16th century, British and French expeditions explored and later settled along the Atlantic coast. As a consequence of various armed conflicts, France ceded nearly all of its colonies in North America in 1763. In 1867, with the union of three British North American colonies through Confederation, Canada was formed as a federal dominion of four provinces. This began an accretion of provinces and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vitamin B12
Vitamin B12, also known as cobalamin, is a water-soluble vitamin involved in metabolism. It is one of eight B vitamins. It is required by animals, which use it as a cofactor in DNA synthesis, in both fatty acid and amino acid metabolism. It is important in the normal functioning of the nervous system via its role in the synthesis of myelin, and in the circulatory system in the maturation of red blood cells in the bone marrow. Plants do not need cobalamin and carry out the reactions with enzymes that are not dependent on it. Vitamin B12 is the most chemically complex of all vitamins, and for humans, the only vitamin that must be sourced from animal-derived foods or from supplements. Only some archaea and bacteria can synthesize vitamin B12. Most people in developed countries get enough B12 from the consumption of meat or foods with animal sources. Foods containing vitamin B12 include meat, clams, liver, fish, poultry, eggs, and dairy products. Many breakfast cereals ar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Watson And Crick
"Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid" was the first article published to describe the discovery of the double helix structure of DNA, using X-ray diffraction and the mathematics of a helix transform. It was published by Francis Crick and James D. Watson in the scientific journal ''Nature'' on pages 737–738 of its 171st volume (dated 25 April 1953). This article is often termed a "pearl" of science because it is brief and contains the answer to a fundamental mystery about living organisms. This mystery was the question of how it is possible that genetic instructions are held inside organisms and how they are passed from generation to generation. The article presents a simple and elegant solution, which surprised many biologists at the time who believed that DNA transmission was going to be more difficult to deduce and understand. The discovery had a major impact on biology, particularly in the field of genetics, enabling later resea ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
William Cochran (physicist)
William (Bill) Cochran (30 July 1922 – 28 August 2003) was a Scottish physicist. Biography Bill Cochran was born in Scotland and educated at Boroughmuir High School in Edinburgh. He studied physics at the University of Edinburgh. He completed his PhD under Arnold Beevers in the Chemistry Department in X-ray crystallography of sucrose using isomorphous replacement. He moved to the University of Cambridge to work with Lawrence Bragg, and obtained tenure in 1951. He realised that isomorphous replacement was the key to solving protein structures. With Francis Crick, he invented methods for deducing helical patterns from crystallographic data, which ultimately led to the solution of the structure of DNA. Cochran went on to study neutron diffraction with Bertram Brockhouse and used lattice dynamics and to explain the phenomenon of ferroelectricity in terms of lattice instabilities. This was tested by his students Stuart Pawley, Roger Cowley and Richard Nelmes. This idea was also ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
