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Judah Folkman
Moses Judah Folkman (February 24, 1933 – January 14, 2008) was an American medical scientist best known for his research on tumor angiogenesis, the process by which a tumor attracts blood vessels to nourish itself and sustain its existence. He founded the field of angiogenesis research, which has led to the discovery of a number of therapies based on inhibiting or stimulating neovascularization. Early life Born in 1933 in Cleveland, Ohio, Judah Folkman accompanied his father, a rabbi, on visits to hospital patients. By age seven, he knew he wanted to be a doctor rather than follow in his father's footsteps, so he could offer cures in addition to comfort. His father replied, "In that case, you can be a rabbi-like doctor," words his son took to heart.Children's Hospital BostoRemembering Judah Folkman: Biography/ref> Career Folkman graduated from Ohio State University in 1953, and then Harvard Medical School in 1957.Harvard Medical SchooBio at Harvard Medical School/ref> While a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cleveland
Cleveland ( ), officially the City of Cleveland, is a city in the U.S. state of Ohio and the county seat of Cuyahoga County. Located in the northeastern part of the state, it is situated along the southern shore of Lake Erie, across the U.S. maritime border with Canada, northeast of Cincinnati, northeast of Columbus, and approximately west of Pennsylvania. The largest city on Lake Erie and one of the major cities of the Great Lakes region, Cleveland ranks as the 54th-largest city in the U.S. with a 2020 population of 372,624. The city anchors both the Greater Cleveland metropolitan statistical area (MSA) and the larger Cleveland–Akron–Canton combined statistical area (CSA). The CSA is the most populous in Ohio and the 17th largest in the country, with a population of 3.63 million in 2020, while the MSA ranks as 34th largest at 2.09 million. Cleveland was founded in 1796 near the mouth of the Cuyahoga River by General Moses Cleaveland, after whom the city ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
United States Navy
The United States Navy (USN) is the maritime service branch of the United States Armed Forces and one of the eight uniformed services of the United States. It is the largest and most powerful navy in the world, with the estimated tonnage of its active battle fleet alone exceeding the next 13 navies combined, including 11 allies or partner nations of the United States as of 2015. It has the highest combined battle fleet tonnage (4,635,628 tonnes as of 2019) and the world's largest aircraft carrier fleet, with eleven in service, two new carriers under construction, and five other carriers planned. With 336,978 personnel on active duty and 101,583 in the Ready Reserve, the United States Navy is the third largest of the United States military service branches in terms of personnel. It has 290 deployable combat vessels and more than 2,623 operational aircraft . The United States Navy traces its origins to the Continental Navy, which was established during the American Re ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Monsanto
The Monsanto Company () was an American agrochemical and agricultural biotechnology corporation founded in 1901 and headquartered in Creve Coeur, Missouri. Monsanto's best known product is Roundup, a glyphosate-based herbicide, developed in the 1970s. Later the company became a major producer of genetically engineered crops. In 2018, the company ranked 199th on the Fortune 500 of the largest United States corporations by revenue. Monsanto was one of four groups to introduce genes into plants in 1983, and was among the first to conduct field trials of genetically modified crops in 1987. It was one of the top 10 US chemical companies until it divested most of its chemical businesses between 1997 and 2002, through a process of mergers and spin-offs that focused the company on biotechnology. Monsanto was one of the first companies to apply the biotechnology industry business model to agriculture, using techniques developed by biotech drug companies. In this business model, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fibroblast Growth Factor
Fibroblast growth factors (FGF) are a family of cell signalling proteins produced by macrophages; they are involved in a wide variety of processes, most notably as crucial elements for normal development in animal cells. Any irregularities in their function lead to a range of developmental defects. These growth factors typically act as systemic or locally circulating molecules of extracellular origin that activate cell surface receptors. A defining property of FGFs is that they bind to heparin and to heparan sulfate. Thus, some are sequestered in the extracellular matrix of tissues that contains heparan sulfate proteoglycans and are released locally upon injury or tissue remodeling. Families In humans, 23 members of the FGF family have been identified, all of which are ''structurally'' related signaling molecules: * Members FGF1 through FGF10 all bind fibroblast growth factor receptors (FGFRs). FGF1 is also known as ''acidic fibroblast growth factor'', and FGF2 is also kno ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bert L
Bert or BERT may refer to: Persons, characters, or animals known as Bert *Bert (name), commonly an abbreviated forename and sometimes a surname *Bert, a character in the poem "Bert the Wombat" by The Wiggles; from their 1992 album Here Comes a Song *Bert (Sesame Street), fictional character on the TV series ''Sesame Street'' *Bert (horse), foaled 1934 *Bert (Mary Poppins), a Cockney chimney sweep in the book series & Disney film ''Mary Poppins'' * Iron Bert (one half of the two yellow diesels 'Arry and Bert), also in ''Thomas and Friends'' Places * Berd, Armenia, also known as Bert *Bert, Allier, a commune in the French of Allier *Bert, West Virginia Electronics & computing *Bit error rate test, a testing method for digital communication circuits *Bit error rate tester, a test equipment used for testing the bit error rate of digital communication circuits *HP Bert, a CPU in certain Hewlett-Packard programmable calculators *BERT (language model) (Bidirectional Encoder Representati ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Solid Tumor
A neoplasm () is a type of abnormal and excessive growth of tissue. The process that occurs to form or produce a neoplasm is called neoplasia. The growth of a neoplasm is uncoordinated with that of the normal surrounding tissue, and persists in growing abnormally, even if the original trigger is removed. This abnormal growth usually forms a mass, when it may be called a tumor. ICD-10 classifies neoplasms into four main groups: benign neoplasms, in situ neoplasms, malignant neoplasms, and neoplasms of uncertain or unknown behavior. Malignant neoplasms are also simply known as cancers and are the focus of oncology. Prior to the abnormal growth of tissue, as neoplasia, cells often undergo an abnormal pattern of growth, such as metaplasia or dysplasia. However, metaplasia or dysplasia does not always progress to neoplasia and can occur in other conditions as well. The word is from Ancient Greek 'new' and 'formation, creation'. Types A neoplasm can be benign, potentially ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
New England Journal Of Medicine
''The New England Journal of Medicine'' (''NEJM'') is a weekly medical journal published by the Massachusetts Medical Society. It is among the most prestigious peer-reviewed medical journals as well as the oldest continuously published one. History In September 1811, John Collins Warren, a Boston physician, along with James Jackson, submitted a formal prospectus to establish the ''New England Journal of Medicine and Surgery and Collateral Branches of Science'' as a medical and philosophical journal. Subsequently, the first issue of the ''New England Journal of Medicine and Surgery and the Collateral Branches of Medical Science'' was published in January 1812. The journal was published quarterly. In 1823, another publication, the ''Boston Medical Intelligencer'', appeared under the editorship of Jerome V. C. Smith. The editors of the ''New England Journal of Medicine and Surgery and the Collateral Branches of Medical Science'' purchased the weekly ''Intelligencer'' for $600 in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Children's Hospital Boston
Boston Children's Hospital formerly known as Children's Hospital Boston until 2012 is a nationally ranked, freestanding acute care children's hospital located in Boston, Massachusetts, adjacent both to its teaching affiliate, Harvard Medical School, and to Dana–Farber Cancer Institute. Dana–Farber and Children's jointly operate the Dana–Farber/Boston Children's Cancer and Blood Disorders Center to deliver comprehensive care for all types of childhood cancers. The hospital is home to the largest hospital-based pediatric research program in the world. The hospital features 485 pediatric beds and provides comprehensive pediatric specialties and subspecialties to infants, children, teens, and young adults aged 0–21 throughout Massachusetts, the United States, and the world. The hospital also sometimes treats adults that require pediatric care. The hospital uses the Brigham and Women's Hospital's rooftop helipad and is an ACS verified level I pediatric trauma center, one ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Patricia K
Patricia is a female given name of Latin origin. Derived from the Latin word '' patrician'', meaning "noble"; it is the feminine form of the masculine given name Patrick. The name Patricia was the second most common female name in the United States according to the 1990 US Census. Another well-known variant of this is " Patrice". According to the US Social Security Administration records, the use of the name for newborns peaked at #3 from 1937 to 1943 in the United States, after which it dropped in popularity, sliding to #745 in 2016.Popularity of a NameSocial Security Administration''ssa.gov'', accessed June 26, 2017 From 1928 to 1967, the name was ranked among the top 11 female names. In Portuguese and Spanish-speaking Latin-American countries, the name Patrícia/Patricia is common as well, pronounced . In Catalan and Portuguese it is written Patrícia, while in Italy, Germany and Austria Patrizia is the form, pronounced . In Polish, the variant is Patrycja. It is also used ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Population Council
The Population Council is an international, nonprofit, non-governmental organization. The Council conducts research in biomedicine, social science, and public health and helps build research capacities in developing countries. One-third of its research relates to HIV and AIDS; while its other major program areas are in reproductive health and its relation to poverty, youth, and gender. For example, the Population Council strives to teach boys that they can be involved in contraceptive methods regardless of stereotypes that limit male responsibility in child bearing. The organization held the license for Norplant contraceptive implant, and now holds the license for Mirena intrauterine system. The Population Council also publishes the journal ''Population and Development Review'', which reports scientific research on the interrelationships between population and socioeconomic development. It also provides a forum for discussion on related issues of public policy and ''Studies in Fa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Norplant
Levonorgestrel-releasing implant, sold under the brand name Jadelle among others, are devices that release levonorgestrel for birth control. It is one of the most effective forms of birth control with a one-year failure rate around 0.05%. The device is placed under the skin and lasts for up to five years. It may be used by women who have a history of pelvic inflammatory disease and therefore cannot use an intrauterine device. Following removal fertility quickly returns. It is generally well tolerated with few significant side effects. Side effects may include irregular menstrual periods, no periods, headaches, and breast pain. Use is not recommended in people with significant liver disease. The levonorgestrel implant is a type of long-acting reversible birth control. It primarily works by stopping ovulation and by thickening the mucus around the cervix. A levonorgestrel-releasing implant was approved for medical use in 1983 in Finland and in the United States in 1990. It is o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lipophilic
Lipophilicity (from Greek λίπος "fat" and φίλος "friendly"), refers to the ability of a chemical compound to dissolve in fats, oils, lipids, and non-polar solvents such as hexane or toluene. Such non-polar solvents are themselves lipophilic (translated as "fat-loving" or "fat-liking"), and the axiom that "like dissolves like" generally holds true. Thus lipophilic substances tend to dissolve in other lipophilic substances, but hydrophilic ("water-loving") substances tend to dissolve in water and other hydrophilic substances. Lipophilicity, hydrophobicity, and non-polarity may describe the same tendency towards participation in the London dispersion force, as the terms are often used interchangeably. However, the terms "lipophilic" and "hydrophobic" are not synonymous, as can be seen with silicones and fluorocarbons, which are hydrophobic but not lipophilic. __TOC__ Surfactants Hydrocarbon-based surfactants are compounds that are amphiphilic (or amphipathic), hav ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
