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José-Alain Sahel
José-Alain Sahel is a French ophthalmologist and scientist. He is currently the Chair of the Department of Ophthalmology at the University of Pittsburgh School of Medicine, Director of the UPMC Vision Institute, and the Eye and Ear Foundation Chair of Ophthalmology. Sahel previously led the Vision Institute (French: Institut de la Vision) in Paris, a research center associated with one of the oldest eye hospitals of Europe, Quinze-Vingts National Eye Hospital in Paris, founded in 1260. He is a pioneer in the field of artificial retina and eye regenerative therapies. He is a member of the French Academy of Sciences. Biography José-Alain Sahel held the chair of the Professor of Ophthalmology at the University Pierre and Marie Curie in Paris and the Professor of Biomedical Sciences (Cumberlege Chair) at University College London. He performed a research fellowship at Massachusetts Eye and Ear Infirmary, Harvard Medical School with Professor Daniel. M. Albert and a visiting scho ...
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French Algeria
French Algeria ( until 1839, then afterwards; unofficially ; ), also known as Colonial Algeria, was the period of History of Algeria, Algerian history when the country was a colony and later an integral part of France. French rule lasted until the end of the Algerian War which resulted in Algeria's Independence Day (Algeria), gaining independence on 5 July 1962. The French conquest of Algeria began in 1830 with the Invasion of Algiers (1830), invasion of Algiers which toppled the Regency of Algiers, though Algeria was not fully conquered and Pacification of Algeria, pacified until 1903. It is estimated that by 1875, approximately 825,000 indigenous Algerians were killed. Various scholars describe the French conquest as genocide. Algeria was ruled as a French colony, colony from 1830 to 1848, and then as multiple Departments of France#Departments of Algeria (Départements d'Algérie), departments, an integral part of France, with the implementing of the French Constitution of 18 ...
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Quinze-Vingts National Ophthalmology Hospital
The Quinze-Vingts National Ophthalmology Hospital (''Centre hospitalier national d’ophtalmologie des Quinze-Vingts'') is France's national ophthalmology hospital located in Paris, in the 12th arrondissement. The hospital gave its name to the ''Quinze-Vingts'' quarter. History The ''Hospice des Quinze-Vingts'', a hospital for the blind, was founded in 1260 by Louis IX, king of France, also known as "Saint Louis". It was constructed on a piece of land called "Champ-Pourri",J-A Delaure et Gabriel Roux, ''Histoire de Paris'', 1853, p. 132 an area lying a short distance west of the Louvre fortress, outside the fortified wall built by Philippe Augustus from 1190 to 1209. It became included within the city after the erection of the new fortified wall of Charles V built between 1356 and 1383. Within the new neighborhood thus formed west of the Louvre, it was located on ''rue Saint-Honoré'' at the corner of the ''rue Saint-Nicaise'', (in the area between the Palais-Royal and Plac ...
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French People Of Algerian Descent
French may refer to: * Something of, from, or related to France ** French language, which originated in France ** French people, a nation and ethnic group ** French cuisine, cooking traditions and practices Arts and media * The French (band), a British rock band * "French" (episode), a live-action episode of ''The Super Mario Bros. Super Show!'' * ''Française'' (film), a 2008 film * French Stewart (born 1964), American actor Other uses * French (surname), a surname (including a list of people with the name) * French (tunic), a type of military jacket or tunic * French's, an American brand of mustard condiment * French (catheter scale), a unit of measurement * French Defence, a chess opening * French kiss, a type of kiss See also * France (other) * Franch, a surname * French Revolution (other) * French River (other), several rivers and other places * Frenching (other) * Justice French (other) Justice French may refer to: * C. G. ...
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1955 Births
Events January * January 3 – José Ramón Guizado becomes president of Panama. * January 17 – , the first Nuclear marine propulsion, nuclear-powered submarine, puts to sea for the first time, from Groton, Connecticut. * January 18–January 20, 20 – Battle of Yijiangshan Islands: The Chinese Communist People's Liberation Army seizes the islands from the Republic of China (Taiwan). * January 22 – In the United States, The Pentagon announces a plan to develop intercontinental ballistic missiles (ICBMs), armed with nuclear weapons. * January 23 – The Sutton Coldfield rail crash kills 17, near Birmingham, England. * January 25 – The Presidium of the Supreme Soviet of the Soviet Union announces the end of the war between the USSR and Germany, which began during World War II in 1941. * January 28 – The United States Congress authorizes President Dwight D. Eisenhower to use force to protect Taiwan from the People's Republic of China. February * February 10 – T ...
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Members Of The French Academy Of Sciences
Member may refer to: * Military jury, referred to as "Members" in military jargon * Element (mathematics), an object that belongs to a mathematical set * In object-oriented programming, a member of a class ** Field (computer science) In data hierarchy, a field (data field) is a Variable (computer science), variable in a record (computer science), record. A record, also known as a data structure, allows logically related data to be identified by a single name. Identifying relate ..., entries in a database ** Member variable, a variable that is associated with a specific object * Limb (anatomy), an appendage of the human or animal body ** Euphemism for penis * Structural component of a truss, connected by nodes * User (computing), a person making use of a computing service, especially on the Internet * Member (geology), a component of a geological formation * Member of parliament * The Members, a British punk rock band * Meronymy, a semantic relationship in linguistics * C ...
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French Ophthalmologists
French may refer to: * Something of, from, or related to France ** French language, which originated in France ** French people, a nation and ethnic group ** French cuisine, cooking traditions and practices Arts and media * The French (band), a British rock band * "French" (episode), a live-action episode of ''The Super Mario Bros. Super Show!'' * ''Française'' (film), a 2008 film * French Stewart (born 1964), American actor Other uses * French (surname), a surname (including a list of people with the name) * French (tunic), a type of military jacket or tunic * French's, an American brand of mustard condiment * French (catheter scale), a unit of measurement * French Defence, a chess opening * French kiss, a type of kiss See also * France (other) * Franch, a surname * French Revolution (other) * French River (other), several rivers and other places * Frenching (other) * Justice French (other) Justice French may refer to: * C. G ...
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Institut Langevin
ESPCI Paris (officially the École supérieure de physique et de chimie industrielles de la ville de Paris, , ''The City of Paris Industrial Physics and Chemistry Higher Educational Institution'') is a grande école founded in 1882 by the city of Paris, France. It educates undergraduate and graduate students in physics, chemistry and biology and conducts high-level research in those fields. It is ranked as the first French ''École d'Ingénieurs'' in the 2017 Shanghai Ranking. ESPCI Paris is a constituent college of Université PSL and a founding member of the ParisTech (Paris Institute of Technology) alliance. Two thirds of the students enter the school following a competitive examination (concours X-ESPCI- ENS) following at least two years of Classes Préparatoires. The other students are recruited by submitting applications. The school itself is also known as Physique-Chimie or simply PC. ESPCI Paris nurtures relationships with many industrial partners such as Schlumberger, ...
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Visual Prosthesis
A visual prosthesis, often referred to as a bionic eye, is a visual device intended to restore functional vision in those with partial or total blindness. Many devices have been developed, usually modeled on the cochlear implant or bionic ear devices, a type of neural prosthesis in use since the mid-1980s. The idea of using electrical current (e.g., electrically stimulating the retina or the visual cortex) to provide sight dates back to the 18th century, discussed by Benjamin Franklin, Tiberius Cavallo, and Charles LeRoy. Biological considerations The ability to give sight to a blind person via a bionic eye depends on the circumstances surrounding the loss of sight. For retinal prostheses, which are the most prevalent visual prosthetic under development (due to ease of access to the retina among other considerations), patients with vision loss due to degeneration of photoreceptors (retinitis pigmentosa, choroideremia, geographic atrophy macular degeneration) are the best c ...
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Pharmacology
Pharmacology is the science of drugs and medications, including a substance's origin, composition, pharmacokinetics, pharmacodynamics, therapeutic use, and toxicology. More specifically, it is the study of the interactions that occur between a living organism and chemicals that affect normal or abnormal biochemical function. If substances have medicinal properties, they are considered pharmaceuticals. The field encompasses drug composition and properties, functions, sources, synthesis and drug design, molecular and cellular mechanisms, organ/systems mechanisms, signal transduction/cellular communication, molecular diagnostics, interactions, chemical biology, therapy, and medical applications and antipathogenic capabilities. The two main areas of pharmacology are pharmacodynamics and pharmacokinetics. Pharmacodynamics studies the effects of a drug on biological systems, and pharmacokinetics studies the effects of biological systems on a drug. In broad terms, pharmacod ...
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Gene Therapy
Gene therapy is Health technology, medical technology that aims to produce a therapeutic effect through the manipulation of gene expression or through altering the biological properties of living cells. The first attempt at modifying human DNA was performed in 1980, by Martin Cline, but the first successful nuclear gene transfer in humans, approved by the National Institutes of Health, was performed in May 1989. The first therapeutic use of gene transfer as well as the first direct insertion of human DNA into the nuclear genome was performed by French Anderson in a trial starting in September 1990. Between 1989 and December 2018, over 2,900 clinical trials were conducted, with more than half of them in Phases of clinical research, phase I. In 2003, Gendicine became the first gene therapy to receive regulatory approval. Since that time, further gene therapy drugs were approved, such as alipogene tiparvovec (2012), Strimvelis (2016), tisagenlecleucel (2017), voretigene neparvovec ...
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Stem Cell
In multicellular organisms, stem cells are undifferentiated or partially differentiated cells that can change into various types of cells and proliferate indefinitely to produce more of the same stem cell. They are the earliest type of cell in a cell lineage. They are found in both embryonic and adult organisms, but they have slightly different properties in each. They are usually distinguished from progenitor cells, which cannot divide indefinitely, and precursor or blast cells, which are usually committed to differentiating into one cell type. In mammals, roughly 50 to 150 cells make up the inner cell mass during the blastocyst stage of embryonic development, around days 5–14. These have stem-cell capability. '' In vivo'', they eventually differentiate into all of the body's cell types (making them pluripotent). This process starts with the differentiation into the three germ layers – the ectoderm, mesoderm and endoderm – at the gastrulation stage. However, whe ...
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Neuroprotection
Neuroprotection refers to the relative preservation of neuronal structure and/or function. In the case of an ongoing insult (a neurodegenerative insult) the relative preservation of neuronal integrity implies a reduction in the rate of neuronal loss over time, which can be expressed as a differential equation. Mechanisms in neurodegeneration, and associated treatments It is a widely explored treatment option for many central nervous system disorders including neurodegenerative diseases, stroke, traumatic brain injury, spinal cord injury, and acute management of neurotoxin consumption (i.e. methamphetamine Methamphetamine (contracted from ) is a potent central nervous system (CNS) stimulant that is mainly used as a recreational drug use, recreational or Performance-enhancing substance, performance-enhancing drug and less commonly as a secon ... overdoses). Neuroprotection aims to prevent or slow disease progression and secondary injuries by halting or at least slowing th ...
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