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John Vane
Sir John Robert Vane (29 March 1927 – 19 November 2004) was a British pharmacologist who was instrumental in the understanding of how aspirin produces pain-relief and anti-inflammatory effects and his work led to new treatments for heart and blood vessel disease and introduction of ACE inhibitors. He was awarded the Nobel Prize in Physiology or Medicine in 1982 along with Sune Bergström and Bengt Samuelsson for "their discoveries concerning prostaglandins and related biologically active substances". Education and early life Born in Tardebigge, Worcestershire, John Vane was one of three children and grew up in suburban Birmingham. His father, Maurice Vane, was the son of Jewish Russian immigrants and his mother, Frances Vane, came from a Worcestershire farming family. He attended a local state school from age 5, before moving on to King Edward's School in Edgbaston, Birmingham. An early interest in chemistry was to prove the inspiration for studying the subject at ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tardebigge
Tardebigge () is a village in Worcestershire, England. The village is most famous for the Tardebigge Locks, a flight of 30 canal locks that raise the Worcester and Birmingham Canal over over the Lickey Ridge. It lies in the county of Worcestershire, although it was also Evolution of Worcestershire county boundaries since 1844, historically an exclave of Staffordshire or Warwickshire at different times in its history. Toponymy ''Tyrde Bicgan'' is Old English for "big tower" or "tower on a hill," reflecting the position of the church. It was called ''Terdeberie'' in the Domesday Book and subsequently spelt ''Tardebigg'', ''Tardebig'', and ''Tarbick''. Eilert Ekwall, however, writes that the name ''Tærdebicga'' has no likely meaning in Old English or Celtic languages, Celtic and calls it "unexplained". History Tardebigge was once a much greater Township (England), township, which included much of Redditch, including the modern day town-centre. Its name was recorded twice in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Aspirin
Aspirin () is the genericized trademark for acetylsalicylic acid (ASA), a nonsteroidal anti-inflammatory drug (NSAID) used to reduce pain, fever, and inflammation, and as an antithrombotic. Specific inflammatory conditions that aspirin is used to treat include Kawasaki disease, pericarditis, and rheumatic fever. Aspirin is also used long-term to help prevent further heart attacks, ischaemic strokes, and blood clots in people at high risk. For pain or fever, effects typically begin within 30 minutes. Aspirin works similarly to other NSAIDs but also suppresses the normal functioning of platelets. One common adverse effect is an upset stomach. More significant side effects include stomach ulcers, stomach bleeding, and worsening asthma. Bleeding risk is greater among those who are older, drink alcohol, take other NSAIDs, or are on other blood thinners. Aspirin is not recommended in the last part of pregnancy. It is not generally recommended in children with infections ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Sheffield
The University of Sheffield (informally Sheffield University or TUOS) is a public university, public research university in Sheffield, South Yorkshire, England. Its history traces back to the foundation of Sheffield Medical School in 1828, Firth College in 1879 and Sheffield Technical School in 1884. The University College of Sheffield was subsequently formed by the amalgamation of the three institutions in 1897 and was granted a royal charter as the University of Sheffield in 1905 by King Edward VII. Sheffield is formed from 50 academic departments which are organised into five faculties and an international faculty. The annual income of the institution for 2023–24 was £887.9 million, of which £185.8 million was from research grants and contracts, with an expenditure of £651.4 million. Sheffield is regarded as one of the top engineering universities in Europe. As of the latest Higher Education Statistics Agency, HESA statistics, it had the highest engineeri ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pharmacology
Pharmacology is the science of drugs and medications, including a substance's origin, composition, pharmacokinetics, pharmacodynamics, therapeutic use, and toxicology. More specifically, it is the study of the interactions that occur between a living organism and chemicals that affect normal or abnormal biochemical function. If substances have medicinal properties, they are considered pharmaceuticals. The field encompasses drug composition and properties, functions, sources, synthesis and drug design, molecular and cellular mechanisms, organ/systems mechanisms, signal transduction/cellular communication, molecular diagnostics, interactions, chemical biology, therapy, and medical applications and antipathogenic capabilities. The two main areas of pharmacology are pharmacodynamics and pharmacokinetics. Pharmacodynamics studies the effects of a drug on biological systems, and pharmacokinetics studies the effects of biological systems on a drug. In broad terms, pharmacod ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bachelor Of Science
A Bachelor of Science (BS, BSc, B.S., B.Sc., SB, or ScB; from the Latin ') is a bachelor's degree that is awarded for programs that generally last three to five years. The first university to admit a student to the degree of Bachelor of Science was the University of London in 1860. In the United States, the Lawrence Scientific School first conferred the degree in 1851, followed by the University of Michigan in 1855. Nathaniel Shaler, who was Harvard's Dean of Sciences, wrote in a private letter that "the degree of Bachelor of Science came to be introduced into our system through the influence of Louis Agassiz, who had much to do in shaping the plans of this School." Whether Bachelor of Science or Bachelor of Arts degrees are awarded in particular subjects varies between universities. For example, an economics student may graduate as a Bachelor of Arts in one university but as a Bachelor of Science in another, and occasionally, both options are offered. Some universities follo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Joshua Harold Burn
Joshua Harold Burn Fellow of the Royal Society, FRS (6 March 1892 – 13 July 1981) was an English pharmacologist and professor of pharmacology, leading the Department of Pharmacology, University of Oxford, Department of Pharmacology. The Nobel Laureate John Vane claimed "If anyone can be said to have moulded the subject of pharmacology around the world, it is he". Life Burn was born in Barnard Castle, County Durham, England.Joshua Harold Burn. 6 March 1892 – 13 July 1981 Edith Bülbring and J. M. Walker Page 47 of 44–89 He was educated at Barnard Castle School. Burn entered Emmanuel College, Cambridge in 1909 where he read the Natural Sciences (Cambridge), Natural Sciences Tripos. He specialised in physiology for Part II. His tutor was Frederick Gowland Hopkins. After receiving his BA he was awarded a research grant by Emmanuel College and a Michael Foster Studentship by the university. The next 18 months were spent in research with Joseph Barcroft. Other figures in physio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Maurice Stacey
Maurice Stacey CBE FRS FRIC (8 April 1907 – 9 October 1994) was a British chemist who worked alongside Sir Norman Haworth to artificially synthesize Vitamin C. Maurice Stacey was born on 8 April 1907 in Moreton, Shropshire. Stacey was educated at Adams Grammar School, Newport and graduated from Birmingham University with the degrees of BSc, PhD and DSc. Stacey began his career at Birmingham University as a demonstrator in chemistry in 1929. He was leader under Sir Norman Haworth of the Birmingham University team which synthesised Vitamin C in 1932. It was Stacey who personally isolated synthetic vitamin C. Stacey was Beit Memorial Fellow for Medical Research at the London School of Tropical Medicine from 1933 to 1937. Stacey returned to Birmingham University in 1937 as lecturer in chemistry and then reader in biological chemistry. Stacey was professor of chemistry at Birmingham University from 1946 to 1956. He was Mason Professor and head of the Department of Chemistry at ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chemistry
Chemistry is the scientific study of the properties and behavior of matter. It is a physical science within the natural sciences that studies the chemical elements that make up matter and chemical compound, compounds made of atoms, molecules and ions: their composition, structure, properties, behavior and the changes they undergo during chemical reaction, reactions with other chemical substance, substances. Chemistry also addresses the nature of chemical bonds in chemical compounds. In the scope of its subject, chemistry occupies an intermediate position between physics and biology. It is sometimes called the central science because it provides a foundation for understanding both Basic research, basic and Applied science, applied scientific disciplines at a fundamental level. For example, chemistry explains aspects of plant growth (botany), the formation of igneous rocks (geology), how atmospheric ozone is formed and how environmental pollutants are degraded (ecology), the prop ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Birmingham
Birmingham ( ) is a City status in the United Kingdom, city and metropolitan borough in the metropolitan county of West Midlands (county), West Midlands, within the wider West Midlands (region), West Midlands region, in England. It is the List of English districts by population, largest local authority district in England by population and the second-largest city in Britain – commonly referred to as the second city of the United Kingdom – with a population of million people in the city proper in . Birmingham borders the Black Country to its west and, together with the city of Wolverhampton and towns including Dudley and Solihull, forms the West Midlands conurbation. The royal town of Sutton Coldfield is incorporated within the city limits to the northeast. The urban area has a population of 2.65million. Located in the West Midlands (region), West Midlands region of England, Birmingham is considered to be the social, cultural, financial and commercial centre of the Midland ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Edgbaston
Edgbaston () is a suburb of Birmingham, West Midlands (county), West Midlands, England. It lies immediately south-west of Birmingham city centre, and was historically in Warwickshire. The Ward (electoral subdivision), wards of Edgbaston and North Edgbaston had a combined population of 42,295 at the 2021 census. Edgbaston is the location of Edgbaston Cricket Ground, the University of Birmingham, Birmingham Botanical Gardens, England, Birmingham Botanical Gardens, and the Edgbaston Archery and Lawn Tennis Society, the oldest Tennis, lawn tennis club in the world. Etymology Edgbaston means "village of a man called Ecgbald", from the Old English language, Old English personal name + ''tun'' "farm". The personal name'' Ecgbald'' means "bold sword" (literally "bold edge"). The name was recorded as a village known as ''Celboldistane'' in the Hundred (county division), Hundred of Hemlingford (hundred), Coleshill in the 1086 Domesday Book until at least 1139, wrongly suggesting that Old ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
King Edward's School, Birmingham
King Edward's School (KES) is an independent school (UK), independent day school for boys in the British Public school (UK), public school tradition, located in Edgbaston, Birmingham. Founded by Edward VI of England, King Edward VI in 1552, it is part of the Foundation of the Schools of King Edward VI. It is a member of the Headmasters' and Headmistresses' Conference. It shares its site and is twinned with King Edward VI High School for Girls (KEHS). While the two schools run separately, dramatic arts, societies, music and other events are often shared; the schools also share a couple of hockey pitches and several clubs. The shared area is called Winterbourne after the nearby Winterbourne Botanic Garden. Since September 2024, the two schools have shared a joint head teacher, styled Chief Master & Principal. Alumni of the school include two Nobel Prize, Nobel laureates, a Fields Medal, Fields medallist, as well as J. R. R. Tolkien (author of ''The Lord of the Rings''), and Fiel ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jews
Jews (, , ), or the Jewish people, are an ethnoreligious group and nation, originating from the Israelites of History of ancient Israel and Judah, ancient Israel and Judah. They also traditionally adhere to Judaism. Jewish ethnicity, religion, and community are highly interrelated, as Judaism is their ethnic religion, though it is not practiced by all ethnic Jews. Despite this, religious Jews regard Gerim, converts to Judaism as members of the Jewish nation, pursuant to the Conversion to Judaism, long-standing conversion process. The Israelites emerged from the pre-existing Canaanite peoples to establish Kingdom of Israel (Samaria), Israel and Kingdom of Judah, Judah in the Southern Levant during the Iron Age.John Day (Old Testament scholar), John Day (2005), ''In Search of Pre-Exilic Israel'', Bloomsbury Publishing, pp. 47.5 [48] 'In this sense, the emergence of ancient Israel is viewed not as the cause of the demise of Canaanite culture but as its upshot'. Originally, J ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
