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John C. Martin (businessman)
John Charles Martin (May 7, 1951 – March 30, 2021) was an American billionaire businessman, and the former executive chairman (2016–2018) and CEO (1996–2016) of the American biotechnology company Gilead Sciences. He joined Gilead Sciences in 1990 as vice president for research and development. Gilead is known for developing drugs such as Atripla (for HIV/AIDS) and commercializing Sovaldi (sofosbuvir) for the treatment of the liver virus hepatitis C. Martin is the recipient of a number of awards, including the Biotechnology Heritage Award (2017). Education Martin earned a bachelor's degree in chemical engineering from Purdue University, an MBA in marketing from Golden Gate University and a PhD in organic chemistry from the University of Chicago. He served on the board of trustees of the latter two universities. Career Syntex Corporation Martin worked at Syntex Corporation from 1978 to 1984. Bristol-Myers Squibb Martin was director of antiviral chemistry at Bristol-Myers S ...
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Easton, Pennsylvania
Easton is a city in, and the county seat of, Northampton County, Pennsylvania, United States. The city's population was 28,127 as of the 2020 census. Easton is located at the confluence of the Lehigh River, a river that joins the Delaware River in Easton and serves as the city's eastern geographic boundary with Phillipsburg, New Jersey. Easton is the easternmost city in the Lehigh Valley, a region of that is Pennsylvania's third largest metropolitan region with 861,889 residents as of the U.S. 2020 census. Of the Valley's three major cities, Allentown, Bethlehem, and Easton, Easton is the smallest with approximately one-fourth the population of Allentown, the Valley's largest city. The greater Easton area includes the city of Easton, three townships ( Forks, Palmer, and Williams), and three boroughs ( Glendon, West Easton, and Wilson). Centre Square, the city's town square in its downtown neighborhood, is home to the Soldiers' and Sailors' Monument, a memorial for E ...
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Biotechnology
Biotechnology is the integration of natural sciences and engineering sciences in order to achieve the application of organisms, cells, parts thereof and molecular analogues for products and services. The term ''biotechnology'' was first used by Károly Ereky in 1919, meaning the production of products from raw materials with the aid of living organisms. Definition The concept of biotechnology encompasses a wide range of procedures for modifying living organisms according to human purposes, going back to domestication of animals, cultivation of the plants, and "improvements" to these through breeding programs that employ artificial selection and hybridization. Modern usage also includes genetic engineering as well as cell and tissue culture technologies. The American Chemical Society defines biotechnology as the application of biological organisms, systems, or processes by various industries to learning about the science of life and the improvement of the value of materia ...
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Presidential Advisory Council On HIV/AIDS
The Presidential Advisory Council on HIV/AIDS (PACHA) advises the White House and the Secretary of Health and Human Services on the US government's response to the AIDS epidemic. The commission was formed by President Bill Clinton in 1995 and each president since has renewed the council's charter. Six members resigned in protest of President Donald Trump's health policies in June 2017, and the remaining ten members were dismissed by Trump on 28 December 2017. While PACHA did not meet in 2018, it was restaffed in 2019 and reconvened in March, June, and October 2019. History The Council was not the first presidential inquiry into HIV. In 1987, Ronald Reagan appointed the President's Commission on the HIV Epidemic (1987–88) to investigate the AIDS epidemic. This was followed by the National Commission on AIDS (1989–1993). Members Current members On Dec. 11, 2018, Secretary Alex Azar of the U.S. Department of Health and Human Services nominated Carl Schmid and John Weism ...
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Centers For Disease Control And Prevention
The Centers for Disease Control and Prevention (CDC) is the national public health agency of the United States. It is a United States federal agency, under the Department of Health and Human Services, and is headquartered in Atlanta, Georgia. The agency's main goal is the protection of public health and safety through the control and prevention of disease, injury, and disability in the US and worldwide. The CDC focuses national attention on developing and applying disease control and prevention. It especially focuses its attention on infectious disease, food borne pathogens, environmental health, occupational safety and health, health promotion, injury prevention and educational activities designed to improve the health of United States citizens. The CDC also conducts research and provides information on non-infectious diseases, such as obesity and diabetes, and is a founding member of the International Association of National Public Health Institutes.
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National Institute Of Allergy And Infectious Diseases
The National Institute of Allergy and Infectious Diseases (NIAID, ) is one of the 27 institutes and centers that make up the National Institutes of Health (NIH), an agency of the United States Department of Health and Human Services (HHS). NIAID's mission is to conduct basic and applied research to better understand, treat, and prevent infectious, immunologic, and allergic diseases. NIAID has on-campus laboratories in Maryland and Hamilton, Montana, and funds research conducted by scientists at institutions in the United States and throughout the world. NIAID also works closely with partners in academia, industry, government, and non-governmental organizations in multifaceted and multidisciplinary efforts to address emerging health challenges such as the H1N1/09 pandemic and the COVID-19 pandemic. History NIAID traces its origins to a small laboratory established in 1887 at the Marine Hospital on Staten Island, New York (now the Bayley Seton Hospital). Officials of the Mar ...
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Federal Government Of The United States
The federal government of the United States (U.S. federal government or U.S. government) is the national government of the United States, a federal republic located primarily in North America, composed of 50 states, a city within a federal district (the city of Washington in the District of Columbia, where most of the federal government is based), five major self-governing territories and several island possessions. The federal government, sometimes simply referred to as Washington, is composed of three distinct branches: legislative, executive, and judicial, whose powers are vested by the U.S. Constitution in the Congress, the president and the federal courts, respectively. The powers and duties of these branches are further defined by acts of Congress, including the creation of executive departments and courts inferior to the Supreme Court. Naming The full name of the republic is "United States of America". No other name appears in the Constitution, and th ...
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California Healthcare Institute
CHI-California Healthcare Institute is a private, non-profit public policy research and advocacy organization, representing more than 250 universities, academic research centers, biotechnology, and medical device companies. Founded in 1993, and based in La Jolla, California, CHI has offices in Washington, D.C., and Sacramento, California. CHI publishes an annual ''California Biomedical Industry'' report, providing data on the scope and scale of academic and commercial life sciences research and development within the state. In 2008, the industry employed more than 270,000 Californians and produced revenues in excess of $75 billion. FDA device approval reform CHI published a study, Competitiveness and Regulation: The FDA and the Future of America’s Biomedical Industry, which concluded that device approval times had increased, that approval times in the European Union were faster than those in the U.S., and that "inefficiency at the FDA had resulted in American inventions made ...
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International Society For Antiviral Research
The International Society for Antiviral Research (ISAR) is a scientific society that focuses on the discovery and clinical application of antiviral agents. It was founded in 1987 to encourage the exchange of information and collaborative research on the development of antiviral, biological and chemical agents. ISAR sponsors the International Conference on Antiviral Research (ICAR), held yearly since 1988 when the second ICAR occurred in Williamsburg, Virginia. ISAR also provides scientific information through peer-reviewed scientific journals and administers several international awards. , the president of the society was Johan Neyts and the president-elect was Kara Carter. Johan Neyts was succeeded as president by Kara Carter, and the president-elect for 2020-2022 became Katherine Seley-Radtke. Founding The foundation for the International Society for Antiviral Research (ISAR) was laid at meetings held in Rotterdam, Netherlands (April 30 – May 3, 1985) and in Il Cio ...
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Specialty Drugs
Specialty drugs or specialty pharmaceuticals are a recent designation of pharmaceuticals that are classified as high-cost, high complexity and/or high touch. Specialty drugs are often biologics—"drugs derived from living cells" that are injectable or infused (although some are oral medications). They are used to treat complex or rare chronic conditions such as cancer, rheumatoid arthritis, hemophilia, H.I.V. psoriasis, inflammatory bowel disease and hepatitis C. In 1990 there were 10 specialty drugs on the market, in the mid-1990s there were fewer than 30, by 2008 there were 200, and by 2015 there were 300. Drugs are often defined as specialty because their price is much higher than that of non-specialty drugs. Medicare defines any drug for which the negotiated price is $670 per month or more, as a specialty drug which is placed in a specialty tier that requires a higher patient cost sharing. Drugs are also identified as specialty when there is a special handling requirement or ...
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Sofosbuvir
Sofosbuvir, sold under the brand name Sovaldi among others, is a medication used to treat hepatitis C. It is taken by mouth. Common side effects include fatigue, headache, nausea, and trouble sleeping. Side effects are generally more common in interferon-containing regimens. Sofosbuvir may reactivate hepatitis B in those who have been previously infected. In combination with ledipasvir, daclatasvir or simeprevir, it is not recommended with amiodarone due to the risk of an abnormally slow heartbeat. Sofosbuvir is in the nucleotide analog family of medications and works by blocking the hepatitis C NS5B protein. Sofosbuvir was discovered in 2007 and approved for medical use in the United States in 2013. It is on the World Health Organization's List of Essential Medicines. Medical uses Initial HCV treatment In 2016, the American Association for the Study of Liver Diseases and the Infectious Diseases Society of America jointly published a recommendation for the mana ...
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Diana DeGette
Diana Louise DeGette (; born July 29, 1957) is an American lawyer and politician serving as the U.S. representative for since 1997. A member of the Democratic Party, her district is based in Denver. DeGette was a Chief Deputy Whip from 2005 to 2019 and is the dean of Colorado's congressional delegation; she served as the Colorado State Representative for the 6th district from 1993 until her election to the U.S. House. Early life, education and career A fourth-generation Coloradan, DeGette was born in Tachikawa, Japan, the daughter of Patricia Anne (''née'' Rose) and Richard Louis DeGette. Her parents were American, and at the time of her birth her father was serving in the armed forces. She graduated from Colorado College, where she earned a B.A. in political science and was elected to the Pi Gamma Mu international honor society in 1979. She earned a Juris Doctor degree from New York University School of Law in 1982. She then returned to Denver and began a law practice f ...
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Frank Pallone
Frank Joseph Pallone Jr. (; born October 30, 1951) is an American lawyer and politician serving as the U.S. representative for , serving since 1988. He is a member of the Democratic Party. The district, numbered as the 3rd district from 1988 to 1993, is in the north-central part of the state and includes New Brunswick, Woodbridge Township, Perth Amboy, Sayreville, Edison, Piscataway and Asbury Park. Pallone is the chair of the House Energy and Commerce Committee. Early life, education, and early political career Pallone is a graduate of Middlebury College, The Fletcher School of Law and Diplomacy at Tufts University, and Rutgers School of Law–Camden. Before being elected to the House, he was a member of the Long Branch city council from 1982 to 1988. Pallone was a member of the New Jersey Senate from the 11th district from 1984 to 1988. In 1983, he defeated incumbent Republican State Senator Brian T. Kennedy 50%-49%. In 1987, he was reelected with 60% of the vote, defeating ...
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