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Johann Peter Gogarten
Johann Peter Gogarten is a German-American biologist studying the early evolution of life. Born in Bad Oeynhausen, Germany, he studied plant physiology and membrane transport with Friedrich-Wilhelm Bentrup in Tübingen and Giessen. In 1987 he moved to the US as a postdoc to work with Lincoln Taiz at UC Santa Cruz. He currently is Distinguished Professor of Molecular and Cell Biology at the University of Connecticut in Storrs, CT. Gogarten was the first person to root the Tree of life (biology) using an ancient gene duplication. He was also one of the pioneers to recognize the importance and the extent of horizontal gene transfer and its role in microbial evolution. Gogarten’s current focus is the evolution of homing endonuclease utilizing parasitic genetic elements (inteins) and the intertwining of selection occurring on the gene, population and the community level (multilevel selection, Unit of selection). J. Peter Gogarten was selected as a recipient of a 2009 Fulbright s ...
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Early Evolution Of Life
The history of life on Earth traces the processes by which living and extinct organisms evolved, from the earliest Abiogenesis, emergence of life to the present day. Earth formed about 4.5 billion years ago (abbreviated as ''Ga'', for ''gigaannum'') and evidence suggests that life emerged prior to 3.7 Ga. The similarities among all known present-day species indicate that they have diverged through the process of evolution from a common ancestor. The earliest clear evidence of life comes from biogenic Δ13C, carbon signatures and stromatolite fossils discovered in 3.7 billion-year-old metasedimentary rocks from western Greenland. In 2015, possible "remains of biotic life" were found in 4.1 billion-year-old rocks in Western Australia. There is further evidence of possibly the oldest forms of life in the form of fossilized microorganisms in hydrothermal vent precipitates from the Nuvvuagittuq Belt, that may have lived as early as 4.28 billion years ago, not long after the Origin ...
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Homing Endonuclease
The homing endonucleases are a collection of endonucleases encoded either as freestanding genes within introns, as fusions with host proteins, or as self-splicing inteins. They catalyze the hydrolysis of genomic DNA within the cells that synthesize them, but do so at very few, or even singular, locations. Repair of the hydrolyzed DNA by the host cell frequently results in the gene encoding the homing endonuclease having been copied into the cleavage site, hence the term 'homing' to describe the movement of these genes. Homing endonucleases can thereby transmit their genes Horizontal gene transfer, horizontally within a host population, increasing their allele frequency at greater than Mendelian rates. Origin and mechanism Although the origin and function of homing endonucleases is still being researched, the most established hypothesis considers them as selfish DNA, selfish genetic elements, similar to transposons, because they facilitate the perpetuation of the genetic elements ...
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University Of California, Santa Cruz Alumni
A university () is an institution of tertiary education and research which awards academic degrees in several academic disciplines. ''University'' is derived from the Latin phrase , which roughly means "community of teachers and scholars". Universities typically offer both undergraduate and postgraduate programs. The first universities in Europe were established by Catholic monks. The University of Bologna (), Italy, which was founded in 1088, is the first university in the sense of: *being a high degree-awarding institute. *using the word (which was coined at its foundation). *having independence from the ecclesiastic schools and issuing secular as well as non-secular degrees (with teaching conducted by both clergy and non-clergy): grammar, rhetoric, logic, theology, canon law and notarial law.Hunt Janin: "The university in medieval life, 1179–1499", McFarland, 2008, , p. 55f.de Ridder-Symoens, Hilde''A History of the University in Europe: Volume 1, Universities in the Midd ...
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Emigrants From West Germany To The United States
Emigration is the act of leaving a resident country or place of residence with the intent to settle elsewhere (to permanently leave a country). Conversely, immigration describes the movement of people into one country from another (to permanently move to a country). A migrant ''emigrates'' from their old country, and ''immigrates'' to their new country. Thus, both emigration and immigration describe migration, but from different countries' perspectives. Demographers examine push and pull factors for people to be pushed out of one place and attracted to another. There can be a desire to escape negative circumstances such as shortages of land or jobs, or unfair treatment. People can be pulled to the opportunities available elsewhere. Fleeing from oppressive conditions, being a refugee and seeking asylum to get refugee status in a foreign country, may lead to permanent emigration. Forced displacement refers to groups that are forced to abandon their native country, such as by en ...
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Year Of Birth Missing (living People)
A year is a unit of time based on how long it takes the Earth to orbit the Sun. In scientific use, the tropical year (approximately 365 solar days, 5 hours, 48 minutes, 45 seconds) and the sidereal year (about 20 minutes longer) are more exact. The modern calendar year, as reckoned according to the Gregorian calendar, approximates the tropical year by using a system of leap years. The term 'year' is also used to indicate other periods of roughly similar duration, such as the lunar year (a roughly 354-day cycle of twelve of the Moon's phasessee lunar calendar), as well as periods loosely associated with the calendar or astronomical year, such as the seasonal year, the fiscal year, the academic year, etc. Due to the Earth's axial tilt, the course of a year sees the passing of the seasons, marked by changes in weather, the hours of daylight, and, consequently, vegetation and soil fertility. In temperate and subpolar regions around the planet, four seasons a ...
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Living People
Purpose: Because living persons may suffer personal harm from inappropriate information, we should watch their articles carefully. By adding an article to this category, it marks them with a notice about sources whenever someone tries to edit them, to remind them of WP:BLP (biographies of living persons) policy that these articles must maintain a neutral point of view, maintain factual accuracy, and be properly sourced. Recent changes to these articles are listed on Special:RecentChangesLinked/Living people. Organization: This category should not be sub-categorized. Entries are generally sorted by family name In many societies, a surname, family name, or last name is the mostly hereditary portion of one's personal name that indicates one's family. It is typically combined with a given name to form the full name of a person, although several give .... Maintenance: Individuals of advanced age (over 90), for whom there has been no new documentation in the last ten ...
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American Academy Of Microbiology
American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, people who self-identify their ancestry as "American" ** American English, the set of varieties of the English language native to the United States ** Native Americans in the United States, indigenous peoples of the United States * American, something of, from, or related to the Americas, also known as "America" ** Indigenous peoples of the Americas * American (word), for analysis and history of the meanings in various contexts Organizations * American Airlines, U.S.-based airline headquartered in Fort Worth, Texas * American Athletic Conference, an American college athletic conference * American Recordings (record label), a record label that was previously known as Def American * American University, in Washington, D.C. Sports teams S ...
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Connecticut Academy Of Science And Engineering
The Connecticut Academy of Science and Engineering (CASE) is a 501(c)3 non-profit institution patterned after the National Academy of Sciences to identify, study, and provide expert guidance on science and technological advancements that are or should be of concern to the state of Connecticut. It was founded in 1976 by Special Act (No. 76-53) of the Connecticut General Assembly The Connecticut General Assembly (CGA) is the state legislature of the U.S. state of Connecticut. It is a bicameral body composed of the 151-member House of Representatives and the 36-member Senate. It meets in the state capital, Hartford. The .... The academy's goals are: to provide information and advice on science and technology to the government, industry and people of Connecticut; to initiate activities that foster science and engineering education of the highest quality, and promote interest in science and engineering on the part of the public, especially young people; and to provide opportuniti ...
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Fulbright Scholarship
The Fulbright Program, including the Fulbright–Hays Program, is one of several United States cultural exchange programs with the goal of improving intercultural relations, cultural diplomacy, and intercultural competence between the people of the United States and other countries through the mutual exchange of persons, knowledge, and skills. The program was founded by United States Senator J. William Fulbright in 1946, and has been considered as one of the most prestigious scholarships in the United States. Via the program, competitively selected American citizens including students, scholars, teachers, professionals, scientists, and artists may receive scholarships or grants to study, conduct research, teach, or exercise their talents abroad; and citizens of other countries may qualify to do the same in the United States. The program provides approximately 8,000 grants annually, comprising roughly 1,600 grants to U.S. students, 1,200 to U.S. scholars, 4,000 to foreign st ...
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Unit Of Selection
A unit of selection is a biological entity within the hierarchy of biological organization (for example, an entity such as: a self-replicating molecule, a gene, a cell, an organism, a group, or a species) that is subject to natural selection. There is debate among evolutionary biologists about the extent to which evolution has been shaped by selective pressures acting at these different levels.Okasha, S. (2006) ''Evolution and the levels of selection''. Oxford University Press. There is debate over the relative importance of the units themselves. For instance, is it group or individual selection that has driven the evolution of altruism? Where altruism reduces the fitness of ''individuals'', individual-centered explanations for the evolution of altruism become complex and rely on the use of game theory, for instance; see kin selection and group selection. There also is debate over the definition of the units themselves, and the roles for selection and replication, and whether ...
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Multilevel Selection
Group selection is a proposed mechanism of evolution in which natural selection acts at the level of the group, instead of at the level of the individual or gene. Early authors such as V. C. Wynne-Edwards and Konrad Lorenz argued that the behavior of animals could affect their survival and reproduction as groups, speaking for instance of actions for the good of the species. In the 1930s, Ronald Fisher and J. B. S. Haldane proposed the concept of kin selection, a form of biological altruism from the gene-centered view of evolution, arguing that animals should sacrifice for their relatives, and thereby implying that they should not sacrifice for non-relatives. From the mid-1960s, evolutionary biologists such as John Maynard Smith, W. D. Hamilton, George C. Williams, and Richard Dawkins argued that natural selection acted primarily at the level of the gene. They argued on the basis of mathematical models that individuals would not altruistically sacrifice fitness for the s ...
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Inteins
Protein splicing is an intramolecular reaction of a particular protein in which an internal protein segment (called an intein) is removed from a precursor protein with a ligation of C-terminal and N-terminal external proteins (called exteins) on both sides. The splicing junction of the precursor protein is mainly a cysteine or a serine, which are amino acids containing a nucleophilic side chain. The protein splicing reactions which are known now do not require exogenous cofactors or energy sources such as adenosine triphosphate (ATP) or guanosine triphosphate (GTP). Normally, splicing is associated only with pre-mRNA splicing. This precursor protein contains three segments—an N-extein followed by the intein followed by a C-extein. After splicing has taken place, the resulting protein contains the N-extein linked to the C-extein; this splicing product is also termed an extein. History The first intein was discovered in 1988 through sequence comparison between the ''Neurospora c ...
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