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Joachim Lingner
Joachim Lingner (born 1962) is a Swiss molecular biologist. He holds the professorship for life sciences and leads the Lingner Lab at the École Polytechnique Fédérale de Lausanne (EPFL). Career Lingner obtained his PhD from the Biozentrum of the University of Basel in 1992. In 1993 he joined the Howard Hughes Medical Institute at University of Colorado at Boulder for postdoctoral studies under the supervision of Thomas Cech. He then joined Swiss Institute for Experimental Cancer Research (ISREC) in Lausanne, Switzerland, first as a junior group leader in 1997 and became senior group leader in 2002. In 2005 he was appointed as associate professor at EPF Lausanne. Since 2009, Lingner is a full professor at EPF Lausanne. Research The Lingner Lab studies of the structure, function and maintenance of telomeres, the nucleoprotein complexes at the ends of eukaryotic chromosomes that enable chromosome stability and that regulate cellular lifespan. They elucidated how telomere sh ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Switzerland
; rm, citad federala, links=no). Swiss law does not designate a ''capital'' as such, but the federal parliament and government are installed in Bern, while other federal institutions, such as the federal courts, are in other cities (Bellinzona, Lausanne, Lucerne, Neuchâtel, St. Gallen a.o.). , coordinates = , largest_city = Zurich , official_languages = , englishmotto = "One for all, all for one" , religion_year = 2022 , religion_ref = , religion = , demonym = , german: link=no, Schweizer/Schweizerin, french: link=no, Suisse/Suissesse, it, svizzero/svizzera or , rm, Svizzer/Svizra , government_type = Federal assembly-independent directorial republic , leader_title1 = Federal Council , leader_name1 = , leader_title2 = , leader_name2 = Viktor Rossi , legislature = Federal Assembly , upper_house = Counci ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Thomas Cech
Thomas Robert Cech (born December 8, 1947) is an American chemist who shared the 1989 Nobel Prize in Chemistry with Sidney Altman, for their discovery of the catalytic properties of RNA. Cech discovered that RNA could itself cut strands of RNA, suggesting that life might have started as RNA. He also studied telomeres, and his lab discovered an enzyme, TERT (telomerase reverse transcriptase), which is part of the process of restoring telomeres after they are shortened during cell division. As president of Howard Hughes Medical Institute, he promoted science education, and he teaches an undergraduate chemistry course at the University of Colorado. Early life and career Cech was born to parents of Czech origin (his grandfather was Czech, his other grandparents were first-generation Americans) in Chicago, he grew up in Iowa City, Iowa. In junior high school, he knocked on the doors of geology professors at the University of Iowa, and asked them to discuss crystal structures, meteori ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Members Of Academia Europaea
Member may refer to: * Military jury, referred to as "Members" in military jargon * Element (mathematics), an object that belongs to a mathematical set * In object-oriented programming, a member of a class ** Field (computer science), entries in a database ** Member variable, a variable that is associated with a specific object * Limb (anatomy), an appendage of the human or animal body ** Euphemism for penis * Structural component of a truss, connected by nodes * User (computing), a person making use of a computing service, especially on the Internet * Member (geology), a component of a geological formation * Member of parliament * The Members, a British punk rock band * Meronymy, a semantic relationship in linguistics * Church membership, belonging to a local Christian congregation, a Christian denomination and the universal Church * Member, a participant in a club or learned society A learned society (; also learned academy, scholarly society, or academic association) is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Living People
Related categories * :Year of birth missing (living people) / :Year of birth unknown * :Date of birth missing (living people) / :Date of birth unknown * :Place of birth missing (living people) / :Place of birth unknown * :Year of death missing / :Year of death unknown * :Date of death missing / :Date of death unknown * :Place of death missing / :Place of death unknown * :Missing middle or first names See also * :Dead people * :Template:L, which generates this category or death years, and birth year and sort keys. : {{DEFAULTSORT:Living people 21st-century people People by status ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1962 Births
Year 196 ( CXCVI) was a leap year starting on Thursday (link will display the full calendar) of the Julian calendar. At the time, it was known as the Year of the Consulship of Dexter and Messalla (or, less frequently, year 949 ''Ab urbe condita''). The denomination 196 for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years. Events By place Roman Empire * Emperor Septimius Severus attempts to assassinate Clodius Albinus but fails, causing Albinus to retaliate militarily. * Emperor Septimius Severus captures and sacks Byzantium; the city is rebuilt and regains its previous prosperity. * In order to assure the support of the Roman legion in Germany on his march to Rome, Clodius Albinus is declared Augustus by his army while crossing Gaul. * Hadrian's wall in Britain is partially destroyed. China * First year of the '' Jian'an era of the Chinese Han Dynasty. * Em ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Swiss Biologists
Swiss may refer to: * the adjectival form of Switzerland * Swiss people Places * Swiss, Missouri *Swiss, North Carolina * Swiss, West Virginia * Swiss, Wisconsin Other uses *Swiss-system tournament A Swiss-system tournament is a non-eliminating tournament format that features a fixed number of rounds of competition, but considerably fewer than for a round-robin tournament; thus each competitor (team or individual) does not play all the other ..., in various games and sports *Swiss International Air Lines **Swiss Global Air Lines, a subsidiary *Swissair, former national air line of Switzerland *.swiss alternative TLD for Switzerland See also *Swiss made, label for Swiss products *Swiss cheese (other) *Switzerland (other) *Languages of Switzerland, none of which are called "Swiss" *International Typographic Style, also known as Swiss Style, in graphic design *Schweizer (other), meaning Swiss in German *Schweitzer, a family name meaning Swiss in Ger ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Academia Europaea
The Academia Europaea is a pan-European Academy of Humanities, Letters, Law, and Sciences. The Academia was founded in 1988 as a functioning Europe-wide Academy that encompasses all fields of scholarly inquiry. It acts as co-ordinator of European interests in national research agencies. History The concept of a 'European Academy of Sciences' was raised at a meeting in Paris of the European Ministers of Science in 1985. The initiative was taken by the Royal Society (United Kingdom) which resulted in a meeting in London in June 1986 of Arnold Burgen (United Kingdom), Hubert Curien (France), Umberto Colombo (Italy), David Magnusson (Sweden), Eugen Seibold (Germany) and Ruurd van Lieshout (the Netherlands) – who agreed to the need for a new body. The two key purposes of Academia Europaea are: * express ideas and opinions of individual scientists from Europe * act as co-ordinator of European interests in national research agencies It does not aim to replace existing national ac ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
EMBO
Embo ( gd, Eurabol, IPA: �iaɾəpɔɫ̪ is a village in the Highland Council Area in Scotland and the former postal county of Sutherland, about north-northeast of Dornoch. On 16 July 1988, Embo declared itself independent from the rest of the United Kingdom for one day. The Prime Minister was Mr. Donald Ward. This was done to raise funds to convert the unused primary school in the village into a community centre. The village issued its own currency, called the Cuddie. The rate of exchange was two Cuddies to the pound. Cuddies were accepted in the local public house, Grannies Heilan' Hame, in exchange for a measure of Clynelish Malt Whisky. The owners of the distillery, in nearby Brora, sponsored the bid for independence by issuing a commemorative label on 50 cases of Clynelish Malt Whisky – "The Spirit of Free Embo". The Battle of Embo took place in 1245 between Scots and Vikings. Bronze Age remains were excavated to the south of the village in 1956, other burials havin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cancer
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements. While these symptoms may indicate cancer, they can also have other causes. Over 100 types of cancers affect humans. Tobacco use is the cause of about 22% of cancer deaths. Another 10% are due to obesity, poor diet, lack of physical activity or excessive drinking of alcohol. Other factors include certain infections, exposure to ionizing radiation, and environmental pollutants. In the developing world, 15% of cancers are due to infections such as '' Helicobacter pylori'', hepatitis B, hepatitis C, human papillomavirus infection, Epstein–Barr virus and human immunodeficiency virus (HIV). These factors act, at least partly, by changing the genes o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Proteome
The proteome is the entire set of proteins that is, or can be, expressed by a genome, cell, tissue, or organism at a certain time. It is the set of expressed proteins in a given type of cell or organism, at a given time, under defined conditions. Proteomics is the study of the proteome. Types of proteomes While proteome generally refers to the proteome of an organism, multicellular organisms may have very different proteomes in different cells, hence it is important to distinguish proteomes in cells and organisms. A cellular proteome is the collection of proteins found in a particular cell type under a particular set of environmental conditions such as exposure to hormone stimulation. It can also be useful to consider an organism's complete proteome, which can be conceptualized as the complete set of proteins from all of the various cellular proteomes. This is very roughly the protein equivalent of the genome. The term ''proteome'' has also been used to refer to the collecti ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Telomerase
Telomerase, also called terminal transferase, is a ribonucleoprotein that adds a species-dependent telomere repeat sequence to the 3' end of telomeres. A telomere is a region of repetitive sequences at each end of the chromosomes of most eukaryotes. Telomeres protect the end of the chromosome from DNA damage or from fusion with neighbouring chromosomes. The fruit fly ''Drosophila melanogaster'' lacks telomerase, but instead uses retrotransposons to maintain telomeres. Telomerase is a reverse transcriptase enzyme that carries its own RNA molecule (e.g., with the sequence 3′- CCC AA UCCC-5′ in '' Trypanosoma brucei'') which is used as a template when it elongates telomeres. Telomerase is active in gametes and most cancer cells, but is normally absent from, or at very low levels in, most somatic cells. History The existence of a compensatory mechanism for telomere shortening was first found by Soviet biologist Alexey Olovnikov in 1973, who also suggested the telomere ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Eukaryotic Chromosome Structure
Eukaryotic chromosome structure refers to the levels of packaging from raw DNA molecules to the chromosomal structures seen during metaphase in mitosis or meiosis. Chromosomes contain long strands of DNA containing genetic information. Compared to prokaryotic chromosomes, eukaryotic chromosomes are much larger in size and are linear chromosomes. Eukaryotic chromosomes are also stored in the cell nucleus, while chromosomes of prokaryotic cells are not stored in a nucleus. Eukaryotic chromosomes require a higher level of packaging to condense the DNA molecules into the cell nucleus because of the larger amount of DNA. This level of packaging includes the wrapping of DNA around proteins called histones in order to form condensed nucleosomes. History The double helix was discovered in 1953 by James Watson and Francis Crick. Other researchers made very important, but unconnected findings about the composition of DNA. Ultimately it was Watson and Crick who put all of these findings toge ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
