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Jens Nielsen
Jens Nielsen is the CEO of BioInnovation Institute, Copenhagen, Denmark, and professor of systems biology at Chalmers University of Technology, Gothenburg, Sweden. He is also an adjunct professor at the Technical University of Denmark. Nielsen is the most cited researcher in the field of metabolic engineering, and he is the founding president of the International Metabolic Engineering Society. He has additionally founded several biotech companies. Education and academic career Jens Nielsen obtained his high school degree from Horsens Statsskole in 1981, and his MSc in chemical engineering (1986) and PhD in biochemical engineering (1989) from the Danish Technical University (DTU). Following his studies, he established an independent research group at DTU and was appointed full professor there in 1998. He was Fulbright visiting professor at MIT in 1995–1996. At DTU, he founded and directed the Center for Microbial Biotechnology. In 2008, he was recruited as professor and dire ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chalmers University Of Technology
Chalmers University of Technology ( sv, Chalmers tekniska högskola, often shortened to Chalmers) is a Swedish university located in Gothenburg that conducts research and education in technology and natural sciences at a high international level. The university has approximately 3100 employees and 10,000 students, and offers education in engineering, science, shipping, architecture and other management areas. Chalmers is coordinating the Graphene Flagship, the European Union's biggest research initiative to bring graphene innovation out of the lab and into commercial applications, and leading the development of a Swedish quantum computer. History The university was founded in 1829 following a donation by William Chalmers, a director of the Swedish East India Company. He donated part of his fortune for the establishment of an "industrial school". Chalmers is one of only three universities in Sweden which are named after a person, the other two being Karolinska Inst ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Aspergillus Oryzae
''Aspergillus oryzae'', also known as , is a filamentous fungus (a mold) used in East Asia to saccharify rice, sweet potato, and barley in the making of alcoholic beverages such as '' sake'' and ''shōchū'', and also to ferment soybeans for making soy sauce and '' miso''. However, in the production of fermented foods of soybeans such as soy sauce and ''miso'', ''Aspergillus sojae'' is sometimes used instead of ''A. oryzae''. Incidentally, in China and Korea, the fungi used for fermented foods for a long time in the production of traditional alcoholic beverages were not ''A. oryzae'' but fungi belonging to '' Rhizopus'' and '' Mucor''. '' A. oryzae'' is also used for the production of rice vinegars. Barley ''kōji'' (麦麹) or rice ''kōji'' (米麹) are made by fermenting the grains with ''A. oryzae'' hyphae. Genomic analysis has led some scholars to believe that the Japanese domesticated the ''Aspergillus flavus'' that had mutated and ceased to produce toxic aflatoxin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Royal Swedish Academy Of Engineering Sciences
The Royal Swedish Academy of Engineering Sciences or ''Kungliga Ingenjörsvetenskapsakademien'' (IVA), founded on 24 October 1919 by King Gustaf V, is one of the royal academies in Sweden. The academy is an independent organisation, which promotes contact and exchange between business, research, and government, in Sweden and internationally. It is the world's oldest academy of engineering sciences.(OECD Reviews of Innovation Policy: Sweden 2012). Leadership The King is the patron of the Academy. The following people have been presidents of IVA since its foundation in 1919: *1919–1940: Axel F. Enström *1941–1959: Edy Velander *1960–1970: Sven Brohult *1971–1982: Gunnar Hambraeus *1982–1994: Hans G. Forsberg *1995–2000: Kurt Östlund *1999–2001: (temporary) Enrico Deiaco *2001–2008: Lena Treschow Torell *2008–2017: Björn O. Nilsson *2017–2023: Tuula Teeri Academy member Each year, outstanding scientists and engineers from universities and industries ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Institute For Medical Engineering And Science
The Institute for Medical Engineering and Science or IMES is a research institute at the Massachusetts Institute of Technology The Massachusetts Institute of Technology (MIT) is a private land-grant research university in Cambridge, Massachusetts. Established in 1861, MIT has played a key role in the development of modern technology and science, and is one of the ... that aims to combine engineering, medicine, and science to solve challenges in human health. The institute was established in 2012 and is currently directed by Elazer Edelman. Some core faculty members include Alex K. Shalek, Emery Brown, and Ellen Roche. IMES serves to bring together scientific advances with clinical medicine by serving as the point of intersection with major hospitals and industry partners. IMES is also the MIT home for the Harvard–MIT Program in Health Sciences and Technology. References External links * {{authority control Engineering research institutes Massachusetts Inst ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Chemical Society
The American Chemical Society (ACS) is a scientific society based in the United States that supports scientific inquiry in the field of chemistry. Founded in 1876 at New York University, the ACS currently has more than 155,000 members at all degree levels and in all fields of chemistry, chemical engineering, and related fields. It is one of the world's largest scientific societies by membership. The ACS is a 501(c)(3) non-profit organization and holds a congressional charter under Title 36 of the United States Code. Its headquarters are located in Washington, D.C., and it has a large concentration of staff in Columbus, Ohio. The ACS is a leading source of scientific information through its peer-reviewed scientific journals, national conferences, and the Chemical Abstracts Service. Its publications division produces over 60 scholarly journals including the prestigious ''Journal of the American Chemical Society'', as well as the weekly trade magazine '' Chemical & Engineeri ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Novo Nordisk Foundation
The Novo Nordisk Foundation is an international enterprise foundation focusing on medical treatment and research. In 2021, the foundation had a net worth of $93.73 billion (697 billion DKK),Novo Nordisk Foundation - Annual report 2021: https://novonordiskfonden.dk/wp-content/uploads/Novo-Nordisk-Foundation-Annual-Report-2021.pdf making it the wealthiest charitable foundation in the world. Novo Nordisk Foundation owns Novo Holdings A/S, a holding company that is the majority shareholder of Novo Nordisk, a Danish pharmaceutical corporation. From 2010 to 2015, the foundation distributed more than US$1.3 billion for research, innovation, treatment, education and humanitarian and social purposes. In 2021, the foundation awarded grants worth $1.18 billion (8.8 billion DKK) and paid out $0.65 billion (4.8 billion DKK). The Foundation typically distributes more than US$300 million each year to research within the fields of Life sciences and Bioscience. While the main focus lies wit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Swedish Chemical Society
The Swedish Chemical Society () was established in 1883 and is a nonprofit organisation A nonprofit organization (NPO) or non-profit organisation, also known as a non-business entity, not-for-profit organization, or nonprofit institution, is a legal entity organized and operated for a collective, public or social benefit, in co ... to promote the development of chemistry in Sweden. The society is based on Wallingatan, Stockholm. () is the monthly magazine of the Swedish Chemical Society. References {{authority control Learned societies of Sweden Chemistry societies Scientific organizations established in 1883 1883 establishments in Sweden ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nature Publishing Group
Nature Portfolio (formerly known as Nature Publishing Group and Nature Research) is a division of the international scientific publishing company Springer Nature that publishes academic journals, magazines, online databases, and services in science and medicine. Nature Research's flagship publication is ''Nature'', a weekly multidisciplinary journal first published in 1869. It also publishes the ''Nature-''titled research journals, ''Nature Reviews'' journals (since 2000), society-owned academic journals, and a range of open access journals, including '' Scientific Reports'' and '' Nature Communications''. Springer Nature also publishes ''Scientific American'' in 16 languages, a magazine intended for the general public. In 2013, prior to the merger with Springer and the creation of Springer Nature, Nature Publishing Group's owner, Holtzbrinck Publishing Group, bought a controlling stake in Frontiers. Before Springer Nature was formed in 2015, Nature Research (as the Nature ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cardiovascular Disease
Cardiovascular disease (CVD) is a class of diseases that involve the heart or blood vessels. CVD includes coronary artery diseases (CAD) such as angina and myocardial infarction (commonly known as a heart attack). Other CVDs include stroke, heart failure, hypertensive heart disease, rheumatic heart disease, cardiomyopathy, abnormal heart rhythms, congenital heart disease, valvular heart disease, carditis, aortic aneurysms, peripheral artery disease, thromboembolic disease, and venous thrombosis. The underlying mechanisms vary depending on the disease. It is estimated that dietary risk factors are associated with 53% of CVD deaths. Coronary artery disease, stroke, and peripheral artery disease involve atherosclerosis. This may be caused by high blood pressure, smoking, diabetes mellitus, lack of exercise, obesity, high blood cholesterol, poor diet, excessive alcohol consumption, and poor sleep, among other things. High blood pressure is estimated to account ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Clear Cell Renal Cell Carcinoma
Clear-cell renal-cell carcinoma (CCRCC) is a type of renal-cell carcinoma. Genetics Cytogenetics * Alterations of chromosome 3p segments occurs in 70–90% of CCRCCs * Inactivation of von Hippel–Lindau disease ( VHL) gene by gene mutation and promoter hypermethylation * Gain of chromosome 5q * Loss of chromosomes 8p, 9p, and 14q Molecular genetics Several frequently mutated genes were discovered in CCRCC: VHL, KDM6A/UTX, SETD2, KDM5C/JARID1C and MLL2. PBRM1 is also commonly mutated in CCRCC. Histogenesis CCRCC is derived from the proximal convoluted tubule. Microscopy Generally, the cells have a clear cytoplasm, are surrounded by a distinct cell membrane and contain round and uniform nuclei. Microscopically, CCRCCs are graded by the ISUP/WHO as follows: Updated: Jul 02, 2019 * Grade 1: Inconspicuous and basophilic nucleoli at magnification of 400 times * Grade 2: Clearly visible and eosinophilic nucleoli at magnification of 400 times * Grade 3: Clear ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer in adults and is currently the most common cause of death in people with cirrhosis. HCC is the third leading cause of cancer-related deaths worldwide. It occurs in the setting of chronic liver inflammation, and is most closely linked to chronic viral hepatitis infection (hepatitis B or C) or exposure to toxins such as alcohol, aflatoxin, or pyrrolizidine alkaloids. Certain diseases, such as hemochromatosis and alpha 1-antitrypsin deficiency, markedly increase the risk of developing HCC. Metabolic syndrome and NASH are also increasingly recognized as risk factors for HCC. As with any cancer, the treatment and prognosis of HCC vary depending on the specifics of tumor histology, size, how far the cancer has spread, and overall health. The vast majority of HCC cases and the lowest survival rates after treatment occur in Asia and sub-Saharan Africa, in countries where hepatitis B infection is ende ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
NAFLD
Non-alcoholic fatty liver disease (NAFLD), also known as metabolic (dysfunction) associated fatty liver disease (MAFLD), is excessive fat build-up in the liver without another clear cause such as alcohol use. There are two types; non-alcoholic fatty liver (NAFL) and non-alcoholic steatohepatitis (NASH), with the latter also including liver inflammation. Non-alcoholic fatty liver is less dangerous than NASH and usually does not progress to NASH. When NAFL does progress to NASH, it may eventually lead to complications such as cirrhosis, liver cancer, liver failure, or cardiovascular disease. Obesity and type 2 diabetes are strong risk factors for NAFLD. Other risks include being overweight, metabolic syndrome (defined as at least three of the five following medical conditions: abdominal obesity, high blood pressure, high blood sugar, high serum triglycerides, and low serum HDL cholesterol), a diet high in fructose, and older age. NAFLD and alcoholic liver disease are types of f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
