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Jens Frahm
Jens Frahm (born 29 March 1951 in Oldenburg, Germany) is a German biophysicist and physicochemist. He is Research Group Leader of the Biomedical NMR group at the Max Planck Institute (MPI) for Multidisciplinary Sciences in Göttingen, Germany (prior to January 1, 2022, at the former MPI for Biophysical Chemistry). Early life and education From 1969 to 1974 Frahm studied physics at the University of Göttingen. His PhD thesis under the guidance of Hans Strehlow at the MPI for Biophysical Chemistry was devoted to the use of nuclear magnetic resonance (NMR) spectroscopy for a characterization of the molecular dynamics of hydrated ions in complex solutions. He received his PhD degree in 1977 in physical chemistry. Career Early Working as a research assistant at the Göttingen MPI since 1977 Frahm formed an independent research team which focused on the new possibilities offered by spatially resolved NMR and magnetic resonance imaging (MRI) – discovered in 1974, by Paul Lauterbur ...
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Oldenburg (city)
Oldenburg (; Northern Low Saxon: ''Ollnborg'') is an independent city in the state of Lower Saxony, Germany. The city is officially named Oldenburg (Oldb) (''Oldenburg in Oldenburg'') to distinguish from Oldenburg in Holstein. During the French annexation (1811–1813) in the wake of the Napoleonic Wars, Napoleonic war against Britain, it was also known as ''Le Vieux-Bourg'' in French. The city is at the rivers Hunte and Haaren (river), Haaren, in the northwestern region between the cities of Bremen in the east and Groningen (Netherlands) in the west. According to Germany's 2022 census, the city's population is 172,759. Oldenburg is part of the Bremen/Oldenburg Metropolitan Region, Northwest Metropolitan Region, which is home to approximately 2.8 million people. The city is the place of origin of the House of Oldenburg. Before the end of the German Empire (1918), it was the administrative centre and residence of the List of rulers of Oldenburg, monarchs of Oldenburg. History ...
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Real-time Computer Graphics
Real-time computer graphics or real-time rendering is the sub-field of computer graphics focused on producing and analyzing images in real time. The term can refer to anything from rendering an application's graphical user interface ( GUI) to real-time image analysis, but is most often used in reference to interactive 3D computer graphics, typically using a graphics processing unit (GPU). One example of this concept is a video game that rapidly renders changing 3D environments to produce an illusion of motion. Computers have been capable of generating 2D images such as simple lines, images and polygons in real time since their invention. However, quickly rendering detailed 3D objects is a daunting task for traditional Von Neumann architecture-based systems. An early workaround to this problem was the use of sprites, 2D images that could imitate 3D graphics. Different techniques for rendering now exist, such as ray-tracing and rasterization. Using these techniques and a ...
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Primates
Primates is an order of mammals, which is further divided into the strepsirrhines, which include lemurs, galagos, and lorisids; and the haplorhines, which include tarsiers and simians ( monkeys and apes). Primates arose 74–63 million years ago first from small terrestrial mammals, which adapted for life in tropical forests: many primate characteristics represent adaptations to the challenging environment among tree tops, including large brain sizes, binocular vision, color vision, vocalizations, shoulder girdles allowing a large degree of movement in the upper limbs, and opposable thumbs (in most but not all) that enable better grasping and dexterity. Primates range in size from Madame Berthe's mouse lemur, which weighs , to the eastern gorilla, weighing over . There are 376–524 species of living primates, depending on which classification is used. New primate species continue to be discovered: over 25 species were described in the 2000s, 36 in the ...
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Insects
Insects (from Latin ') are hexapod invertebrates of the class Insecta. They are the largest group within the arthropod phylum. Insects have a chitinous exoskeleton, a three-part body (head, thorax and abdomen), three pairs of jointed legs, compound eyes, and a pair of antennae. Insects are the most diverse group of animals, with more than a million described species; they represent more than half of all animal species. The insect nervous system consists of a brain and a ventral nerve cord. Most insects reproduce by laying eggs. Insects breathe air through a system of paired openings along their sides, connected to small tubes that take air directly to the tissues. The blood therefore does not carry oxygen; it is only partly contained in vessels, and some circulates in an open hemocoel. Insect vision is mainly through their compound eyes, with additional small ocelli. Many insects can hear, using tympanal organs, which may be on the legs or other parts of the b ...
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Central Nervous System
The central nervous system (CNS) is the part of the nervous system consisting primarily of the brain, spinal cord and retina. The CNS is so named because the brain integrates the received information and coordinates and influences the activity of all parts of the bodies of bilateria, bilaterally symmetric and triploblastic animals—that is, all multicellular animals except sponges and Coelenterata, diploblasts. It is a structure composed of nervous tissue positioned along the Anatomical_terms_of_location#Rostral,_cranial,_and_caudal, rostral (nose end) to caudal (tail end) axis of the body and may have an enlarged section at the rostral end which is a brain. Only arthropods, cephalopods and vertebrates have a true brain, though precursor structures exist in onychophorans, gastropods and lancelets. The rest of this article exclusively discusses the vertebrate central nervous system, which is radically distinct from all other animals. Overview In vertebrates, the brain and spinal ...
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Noninvasive
Minimally invasive procedures (also known as minimally invasive surgeries) encompass surgical techniques that limit the size of incisions needed, thereby reducing wound healing time, associated pain, and risk of infection. Surgery by definition is invasive, and many operations requiring incisions of some size are referred to as ''open surgery''. Incisions made during open surgery can sometimes leave large wounds that may be painful and take a long time to heal. Advancements in medical technologies have enabled the development and regular use of minimally invasive procedures. For example, endovascular aneurysm repair, a minimally invasive surgery, has become the most common method of repairing abdominal aortic aneurysms in the US as of 2003. The procedure involves much smaller incisions than the corresponding open surgery procedure of open aortic surgery. Interventional radiologists were the forerunners of minimally invasive procedures. Using imaging techniques, radiologists ...
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Neurobiology
Neuroscience is the scientific study of the nervous system (the brain, spinal cord, and peripheral nervous system), its functions, and its disorders. It is a multidisciplinary science that combines physiology, anatomy, molecular biology, developmental biology, cytology, psychology, physics, computer science, chemistry, medicine, statistics, and Mathematical Modeling, mathematical modeling to understand the fundamental and emergent properties of neurons, glia and neural circuits. The understanding of the biological basis of learning, memory, behavior, perception, and consciousness has been described by Eric Kandel as the "epic challenge" of the Biology, biological sciences. The scope of neuroscience has broadened over time to include different approaches used to study the nervous system at different scales. The techniques used by neuroscientists have expanded enormously, from molecular and cell biology, cellular studies of individual neurons to neuroimaging, imaging of Sen ...
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Max Planck Institute For Dynamics And Self-Organization
The Max Planck Institute for Dynamics and Self-Organization in Göttingen, Germany, is a research institute for investigations of complex non-equilibrium systems, particularly in physics and biology. Its founding history goes back to Ludwig Prandtl who in 1911 requested a Kaiser Wilhelm Institute to be founded for the investigation of aerodynamics and hydrodynamics. As a first step the ''Aeronautische Versuchsanstalt'' (now the DLR) was established in 1915 and then finally the Kaiser Wilhelm Institute for Flow Research was established in 1924. In 1948 it became part of the Max Planck Society. The Max Planck Society was founded in this institute. In 2003 it was renamed to Max Planck Institute for Dynamics and Self-Organization. It is one of 80 institutes in the Max Planck Society (Max Planck Gesellschaft). History The early history of the Max Planck Institute for Dynamics and Self-Organization is closely linked to the work of the famous physicist Ludwig Prandtl. Prandtl is re ...
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Not-for-profit
A not-for-profit or non-for-profit organization (NFPO) is a Legal Entity, legal entity that does not distribute surplus funds to its members and is formed to fulfill specific objectives. While not-for-profit organizations and Nonprofit organization, non-profit organizations (NPO) are distinct legal entities, the terms are sometimes used interchangeably. An NFPO must be differentiated from a NPO as they are not formed explicitly for the Public good (economics), public good as an NPO must be, and NFPOs are considered "recreational organizations", meaning that they do not operate with the goal of generating revenue as opposed to NPOs. Functions An NFPO does not have the same obligation as an NPO to serve the public good, and as such it may be used to apply for Tax exemption, tax-exempt status as an organization that serves its members and does not have the goal of generating profit. An example of this is a sports club, which exists for the enjoyment of its members and thus wou ...
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Magnetic Resonance Spectroscopy
Nuclear magnetic resonance spectroscopy, most commonly known as NMR spectroscopy or magnetic resonance spectroscopy (MRS), is a spectroscopic technique based on re-orientation of atomic nuclei with non-zero nuclear spins in an external magnetic field. This re-orientation occurs with absorption of electromagnetic radiation in the radio frequency region from roughly 4 to 900 MHz, which depends on the isotopic nature of the nucleus and increases proportionally to the strength of the external magnetic field. Notably, the resonance frequency of each NMR-active nucleus depends on its chemical environment. As a result, NMR spectra provide information about individual functional groups present in the sample, as well as about connections between nearby nuclei in the same molecule. As the NMR spectra are unique or highly characteristic to individual compounds and functional groups, NMR spectroscopy is one of the most important methods to identify molecular structures, particularly of ...
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Magnetic Resonance Angiography
Magnetic resonance angiography (MRA) is a group of techniques based on magnetic resonance imaging (MRI) to image blood vessels. Magnetic resonance angiography is used to generate images of arteries (and less commonly veins) in order to evaluate them for stenosis (abnormal narrowing), Vascular occlusion, occlusions, aneurysms (vessel wall dilatations, at risk of rupture) or other abnormalities. MRA is often used to evaluate the arteries of the neck and brain, the thoracic and abdominal aorta, the renal arteries, and the legs (the latter exam is often referred to as a "run-off"). Acquisition A variety of techniques can be used to generate the pictures of blood vessels, both artery, arteries and veins, based on flow effects or on contrast (inherent or pharmacologically generated). The most frequently applied MRA methods involve the use intravenous MRI contrast agent, contrast agents, particularly those containing gadolinium to shorten the Spin–lattice relaxation, ''T''1 of bloo ...
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Brain
The brain is an organ (biology), organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals. It consists of nervous tissue and is typically located in the head (cephalization), usually near organs for special senses such as visual perception, vision, hearing, and olfaction. Being the most specialized organ, it is responsible for receiving information from the sensory nervous system, processing that information (thought, cognition, and intelligence) and the coordination of motor control (muscle activity and endocrine system). While invertebrate brains arise from paired segmental ganglia (each of which is only responsible for the respective segmentation (biology), body segment) of the ventral nerve cord, vertebrate brains develop axially from the midline dorsal nerve cord as a brain vesicle, vesicular enlargement at the rostral (anatomical term), rostral end of the neural tube, with centralized control over all body segments. All vertebr ...
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