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James Leonard Corning
James Leonard Corning (1855 – 1923) was an American neurologist, mainly known for his early experiments on neuraxial blockade in New York City. Education Corning was born in Stamford, Connecticut. When the American Civil War began in 1861, Corning's family moved to Stuttgart, Germany. Corning studied chemistry at the Stuttgart Polytechnic Institute under Hermann von Fehling. He later studied physiology at Heidelberg University under Wilhelm Kühne, and pathology at the University of Würzburg. After receiving his medical degree in 1878, he left Germany and visited Vienna, Paris, and London before finally returning to the United States. Neuraxial blockade In 1884, Karl Koller became the first to describe the anesthetic properties of cocaine. The following year, Corning injected cocaine between the spinous processes of the lower lumbar vertebrae, first in a dog and then in a healthy man. His experiments are the first published descriptions of the principle of neuraxial ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stamford, Connecticut
Stamford () is a city in the U.S. state of Connecticut, outside of Manhattan. It is Connecticut's second-most populous city, behind Bridgeport. With a population of 135,470, Stamford passed Hartford and New Haven in population as of the 2020 census. It is in the Bridgeport-Stamford-Norwalk-Danbury metropolitan statistical area, which is part of the New York City metropolitan area (specifically, the New York–Newark, NY–NJ–CT–PA Combined Statistical Area). As of 2019, Stamford is home to nine Fortune 500 companies and numerous divisions of large corporations. This gives it the largest financial district in the New York metropolitan region outside New York City and one of the nation's largest concentrations of corporations. Dominant sectors of Stamford's economy include financial services, tourism, information technology, healthcare, telecommunications, transportation, and retail. Its metropolitan division is home to colleges and universities including UConn ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Medical Degree
A medical degree is a professional degree admitted to those who have passed coursework in the fields of medicine and/or surgery from an accredited medical school. Obtaining a degree in medicine allows for the recipient to continue on into specialty training with the end goal of securing a license to practice within their respective jurisdiction. Medical graduates may also pursue non-clinical careers including those in basic research and positions within the healthcare industry. A worldwide study conducted in 2011 indicated on average: 64 university exams, 130 series exams, and 174 assignments are completed over the course of 5.5 years. As a baseline, students need greater than an 85% in prerequisite courses to enroll for the aptitude test in these degree programs. Undergraduate medical degrees * Bachelor of Medicine, Bachelor of Surgery (MBBS, BMBS, MBChB, MBBCh) * Bachelor of Medicine (B.Med, MB, BM) * Bachelor of Surgery (B.S)/(B.Surg) The MBBS is also awarded at the grad ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Epidural
Epidural administration (from Ancient Greek ἐπί, , upon" + ''dura mater'') is a method of medication administration in which a medicine is injected into the epidural space around the spinal cord. The epidural route is used by physicians and nurse anesthetists to administer local anesthetic agents, analgesics, diagnostic medicines such as radiocontrast agents, and other medicines such as glucocorticoids. Epidural administration involves the placement of a catheter into the epidural space, which may remain in place for the duration of the treatment. The technique of intentional epidural administration of medication was first described in 1921 by Spanish military surgeon Fidel Pagés. In the United States, over 50% of childbirths involve the use of epidural anesthesia. Epidural anaesthesia causes a loss of sensation, including pain, by blocking the transmission of signals through nerve fibres in or near the spinal cord. For this reason, epidurals are commonly used for ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kiel
Kiel () is the capital and most populous city in the northern German state of Schleswig-Holstein, with a population of 246,243 (2021). Kiel lies approximately north of Hamburg. Due to its geographic location in the southeast of the Jutland peninsula on the southwestern shore of the Baltic Sea, Kiel has become one of Germany's major maritime centres, known for a variety of international sailing events, including the annual Kiel Week, which is the biggest sailing event in the world. Kiel is also known for the Kiel Mutiny, when sailors refused to board their vessels in protest against Germany's further participation in World War I, resulting in the abdication of the Kaiser and the formation of the Weimar Republic. The Olympic sailing competitions of the 1936 and the 1972 Summer Olympics were held in the Bay of Kiel. Kiel has also been one of the traditional homes of the German Navy's Baltic fleet, and continues to be a major high-tech shipbuilding centre. Located in Kiel is the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Spinal Anaesthesia
Spinal anaesthesia (or spinal anesthesia), also called spinal block, subarachnoid block, intradural block and intrathecal block, is a form of neuraxial regional anaesthesia involving the injection of a local anaesthetic or opioid into the subarachnoid space, generally through a fine needle, usually long. It is a safe and effective form of anesthesia usually performed by anesthesiologists that can be used as an alternative to general anesthesia commonly in surgeries involving the lower extremities and surgeries below the umbilicus. The local anesthetic with or without an opioid injected into the cerebrospinal fluid provides locoregional anaesthesia: true analgesia, motor, sensory and autonomic (sympathic) blockade. Administering analgesics (opioid, alpha2-adrenoreceptor agonist) in the cerebrospinal fluid without a local anaesthetic produces locoregional analgesia: markedly reduced pain sensation (incomplete analgesia), some autonomic blockade (parasympathetic plexi), but no s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
August Bier
August Karl Gustav Bier (24 November 1861 – 12 March 1949) was a German surgeon. He was the first to perform spinal anesthesia and intravenous regional anesthesia. Early medical career Bier began his medical education at the Charité – Universitätsmedizin Berlin in 1881, transferred to the Leipzig University in 1882, and transferred again to the University of Kiel in 1883. After receiving his medical degree from the University of Kiel in 1886, Bier worked as a general practitioner and ship's surgeon just outside the city of Kiel – which is a major port on the Baltic Sea. Bier began his residency in 1888 at the surgical clinic at the University of Kiel, under the mentorship of Friedrich von Esmarch. After professorships in Greifswald and Bonn, Bier was appointed Chief Surgeon and Geheimrat Professor of Surgery at the Charité - Universitätsmedizin. Spinal anesthesia On 16 August 1898, Bier performed the first operation under spinal anesthesia at the Royal Surgical Ho ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lumbar Vertebrae
The lumbar vertebrae are, in human anatomy, the five vertebrae between the rib cage and the pelvis. They are the largest segments of the vertebral column and are characterized by the absence of the foramen transversarium within the transverse process (since it is only found in the cervical region) and by the absence of facets on the sides of the body (as found only in the thoracic region). They are designated L1 to L5, starting at the top. The lumbar vertebrae help support the weight of the body, and permit movement. Human anatomy General characteristics The adjacent figure depicts the general characteristics of the first through fourth lumbar vertebrae. The fifth vertebra contains certain peculiarities, which are detailed below. As with other vertebrae, each lumbar vertebra consists of a ''vertebral body'' and a ''vertebral arch''. The vertebral arch, consisting of a pair of ''pedicles'' and a pair of ''laminae'', encloses the ''vertebral foramen'' (opening) and s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Spinous Process
The spinal column, a defining synapomorphy shared by nearly all vertebrates, Hagfish are believed to have secondarily lost their spinal column is a moderately flexible series of vertebrae (singular vertebra), each constituting a characteristic irregular bone whose complex structure is composed primarily of bone, and secondarily of hyaline cartilage. They show variation in the proportion contributed by these two tissue types; such variations correlate on one hand with the cerebral/caudal rank (i.e., location within the backbone), and on the other with phylogenetic differences among the vertebrate taxa. The basic configuration of a vertebra varies, but the bone is its ''body'', with the central part of the body constituting the ''centrum''. The upper (closer to) and lower (further from), respectively, the cranium and its central nervous system surfaces of the vertebra body support attachment to the intervertebral discs. The posterior part of a vertebra forms a vertebral a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Injection (medicine)
An injection (often and usually referred to as a "shot" in US English, a "jab" in UK English, or a "jag" in Scottish English and Scots) is the act of administering a liquid, especially a drug, into a person's body using a needle (usually a hypodermic needle) and a syringe. An injection is considered a form of parenteral drug administration; it does not involve absorption in the digestive tract. This allows the medication to be absorbed more rapidly and avoid the first pass effect. There are many types of injection, which are generally named after the body tissue the injection is administered into. This includes common injections such as subcutaneous, intramuscular, and intravenous injections, as well as less common injections such as intraperitoneal, intraosseous, intracardiac, intraarticular, and intracavernous injections. Injections are among the most common health care procedures, with at least 16 billion administered in developing and transitional countries each ye ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cocaine
Cocaine (from , from , ultimately from Quechua: ''kúka'') is a central nervous system (CNS) stimulant mainly used recreationally for its euphoric effects. It is primarily obtained from the leaves of two Coca species native to South America, '' Erythroxylum coca'' and '' Erythroxylum novogranatense''. After extraction from coca leaves and further processing into cocaine hydrochloride (powdered cocaine), the drug is often snorted, applied topically to the mouth, or dissolved and injected into a vein. It can also then be turned into free base form (crack cocaine), in which it can be heated until sublimated and then the vapours can be inhaled. Cocaine stimulates the reward pathway in the brain. Mental effects may include an intense feeling of happiness, sexual arousal, loss of contact with reality, or agitation. Physical effects may include a fast heart rate, sweating, and dilated pupils. High doses can result in high blood pressure or high body temperature. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anesthetic
An anesthetic (American English) or anaesthetic (British English; see spelling differences) is a drug used to induce anesthesia — in other words, to result in a temporary loss of sensation or awareness. They may be divided into two broad classes: general anesthetics, which result in a reversible loss of consciousness, and local anesthetics, which cause a reversible loss of sensation for a limited region of the body without necessarily affecting consciousness. A wide variety of drugs are used in modern anesthetic practice. Many are rarely used outside anesthesiology, but others are used commonly in various fields of healthcare. Combinations of anesthetics are sometimes used for their synergistic and additive therapeutic effects. Adverse effects, however, may also be increased. Anesthetics are distinct from analgesics, which block only sensation of painful stimuli. Local anesthetics Local anesthetic agents prevent the transmission of nerve impulses without ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Karl Koller (ophthalmologist)
Karl Koller (December 3, 1857 – March 21, 1944) was an Austrian ophthalmologist who began his medical career as a surgeon at the Vienna General Hospital and a colleague of Sigmund Freud. Koller introduced cocaine as a local anaesthetic for eye surgery. Prior to this discovery, he had tested solutions such as chloral hydrate and morphine as anaesthetics in the eyes of laboratory animals without success. Freud was fully aware of the pain-killing properties of cocaine, but Koller recognized its tissue-numbing capabilities, and in 1884 demonstrated its potential as a local anaesthetic to the medical community. Koller's findings were a medical breakthrough. Prior to his discovery, performing eye surgery was difficult because the involuntary reflex motions of the eye to respond to the slightest stimuli. Later, cocaine was also used as a local anaesthetic in other medical fields such as dentistry. In the 20th century, other agents such as lidocaine have replaced cocaine as a local ana ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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