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Irwin Gunsalus
Irwin C. "Gunny" Gunsalus (June 29, 1912 – October 25, 2008) was an American biochemist who discovered lipoic acid, a vitamin-like substance (an enzyme cofactor) that has been used as a treatment for chronic liver disease, and pyridoxal phosphate, one of the active forms of vitamin B6. In his role as assistant secretary general at the United Nations, he led the international body's research on genetic engineering. Early life Gunsalus was born June 29, 1912, in Sully County, South Dakota, at the homestead of his family farm. His father was killed in a threshing machine accident before Gunsalus started college. He attended South Dakota State University before transferring to Cornell University, where he studied bacteriology, earning a bachelor's degree in 1933, a master's in 1937 and was awarded a doctoral degree in the field in 1940. Academic career Gunsalus taught bacteriology from 1940 to 1947 at Cornell University. There he studied issues of food safety and disease ris ...
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Sully County, South Dakota
Sully County is a county in the U.S. state of South Dakota. As of the 2020 census, the population was 1,446, making it the fifth-least populous county in South Dakota. Its county seat is Onida. The county was created in 1873 and organized in 1883. It is named after General Alfred Sully, who built Fort Sully. Sully County is included in the Micropolitan Statistical Area of Pierre. Sully County was the location of the largest African American homesteader settlement in the state, the Blair Colony. An Illinois man named Norvel Blair arrived in Fairbank Township in 1884, after sending his sons Benjamin and Patrick to investigate the area for settlement. Blair's financial success, achieved through farming and breeding racehorses, attracted dozens of other Black families to the colony. Blair became the first Black South Dakotan to serve on a school board. The decline of South Dakota agriculture during the Great Depression led most Blair Colony residents to seek work in larg ...
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United Nations
The United Nations (UN) is the Earth, global intergovernmental organization established by the signing of the Charter of the United Nations, UN Charter on 26 June 1945 with the stated purpose of maintaining international peace and international security, security, to develop friendly Diplomacy, relations among State (polity), states, to promote international cooperation, and to serve as a centre for harmonizing the actions of states in achieving those goals. The United Nations headquarters is located in New York City, with several other offices located in United Nations Office at Geneva, Geneva, United Nations Office at Nairobi, Nairobi, United Nations Office at Vienna, Vienna, and The Hague. The UN comprises six principal organizations: the United Nations General Assembly, General Assembly, the United Nations Security Council, Security Council, the United Nations Economic and Social Council, Economic and Social Council, the International Court of Justice, the United Nations Se ...
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Alzheimer's Disease
Alzheimer's disease (AD) is a neurodegenerative disease and the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in remembering recent events. As the disease advances, symptoms can include problems with language, disorientation (including easily getting lost), mood swings, loss of motivation, self-neglect, and behavioral issues. As a person's condition declines, they often withdraw from family and society. Gradually, bodily functions are lost, ultimately leading to death. Although the speed of progression can vary, the average life expectancy following diagnosis is three to twelve years. The causes of Alzheimer's disease remain poorly understood. There are many environmental and genetic risk factors associated with its development. The strongest genetic risk factor is from an allele of apolipoprotein E. Other risk factors include a history of head injury, clinical depression, and high blood pressure. The progression of the di ...
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Pancreatic Cancer
Pancreatic cancer arises when cell (biology), cells in the pancreas, a glandular organ behind the stomach, begin to multiply out of control and form a Neoplasm, mass. These cancerous cells have the malignant, ability to invade other parts of the body. A number of types of pancreatic cancer are known. The most common, pancreatic adenocarcinoma, accounts for about 90% of cases, and the term "pancreatic cancer" is sometimes used to refer only to that type. These adenocarcinomas start within the part of the pancreas that makes digestive enzymes. Several other types of cancer, which collectively represent the majority of the non-adenocarcinomas, can also arise from these cells. About 1–2% of cases of pancreatic cancer are neuroendocrine tumors, which arise from the hormone-producing neuroendocrine cell, cells of the pancreas. These are generally less aggressive than pancreatic adenocarcinoma. Signs and symptoms of the most-common form of pancreatic cancer may include jaundice, ...
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Carbohydrate
A carbohydrate () is a biomolecule composed of carbon (C), hydrogen (H), and oxygen (O) atoms. The typical hydrogen-to-oxygen atomic ratio is 2:1, analogous to that of water, and is represented by the empirical formula (where ''m'' and ''n'' may differ). This formula does not imply direct covalent bonding between hydrogen and oxygen atoms; for example, in , hydrogen is covalently bonded to carbon, not oxygen. While the 2:1 hydrogen-to-oxygen ratio is characteristic of many carbohydrates, exceptions exist. For instance, uronic acids and deoxy-sugars like fucose deviate from this precise stoichiometric definition. Conversely, some compounds conforming to this definition, such as formaldehyde and acetic acid, are not classified as carbohydrates. The term is predominantly used in biochemistry, functioning as a synonym for saccharide (), a group that includes sugars, starch, and cellulose. The saccharides are divided into four chemical groups: monosaccharides, disaccharides, ...
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Gastrointestinal Tract
The gastrointestinal tract (GI tract, digestive tract, alimentary canal) is the tract or passageway of the Digestion, digestive system that leads from the mouth to the anus. The tract is the largest of the body's systems, after the cardiovascular system. The GI tract contains all the major organ (biology), organs of the digestive system, in humans and other animals, including the esophagus, stomach, and intestines. Food taken in through the mouth is digestion, digested to extract nutrients and absorb energy, and the waste expelled at the anus as feces. ''Gastrointestinal'' is an adjective meaning of or pertaining to the stomach and intestines. Nephrozoa, Most animals have a "through-gut" or complete digestive tract. Exceptions are more primitive ones: sponges have small pores (ostium (sponges), ostia) throughout their body for digestion and a larger dorsal pore (osculum) for excretion, comb jellies have both a ventral mouth and dorsal anal pores, while cnidarians and acoels have ...
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Lactic Acid Bacteria
Lactobacillales are an order of gram-positive, low-GC, acid-tolerant, generally nonsporulating, nonrespiring, either rod-shaped (bacilli) or spherical ( cocci) bacteria that share common metabolic and physiological characteristics. These bacteria, usually found in decomposing plants and milk products, produce lactic acid as the major metabolic end product of carbohydrate fermentation, giving them the common name lactic acid bacteria (LAB). Production of lactic acid has linked LAB with food fermentations, as acidification inhibits the growth of spoilage agents. Proteinaceous bacteriocins are produced by several LAB strains and provide an additional hurdle for spoilage and pathogenic microorganisms. Furthermore, lactic acid and other metabolic products contribute to the organoleptic and textural profile of a food item. The industrial importance of the LAB is further evidenced by their generally recognized as safe (GRAS) status, due to their ubiquitous appearance in food and the ...
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Enterococcus
''Enterococcus'' is a large genus of lactic acid bacteria of the phylum Bacillota. Enterococci are Gram-positive cocci that often occur in pairs ( diplococci) or short chains, and are difficult to distinguish from streptococci on physical characteristics alone. Two species are common commensal organisms in the intestines of humans: '' E. faecalis'' (90–95%) and '' E. faecium'' (5–10%). Rare clusters of infections occur with other species, including '' E. durans'' , ''E. casseliflavus'', '' E. gallinarum'', and ''E. raffinosus''. Physiology and classification Enterococci are facultative anaerobic organisms, i.e., they are capable of cellular respiration in both oxygen-rich and oxygen-poor environments. Though they are not capable of forming spores, enterococci are tolerant of a wide range of environmental conditions: extreme temperature (10–45 °C), pH (4.6–9.9), and high sodium chloride concentrations. ''E. faecium'' and ''E. faecalis'' can be differentiated ...
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Roger Stanier
Roger Yate Stanier (22 October 1916 – 29 January 1982) was a Canadian microbiologist who was influential in the development of modern microbiology. As a member of the Delft School and former student of C. B. van Niel, he made important contributions to the taxonomy of bacteria, including the classification of blue-green algae as cyanobacteria. In 1957, he and co-authors wrote ''The Microbial World'', an influential microbiology textbook which was published in five editions over three decades. In the course of 24 years at the University of California, Berkeley he reached the rank of professor and served as chair of the Department of Bacteriology before leaving for the Pasteur Institute in 1971. He received several awards over the course of his career, including the Leeuwenhoek Medal. He was a Fellow of the Royal Society and a Foreign Associate of the National Academy of Sciences and the Légion d’Honneur. Early life Roger Yate Stanier was born to British immigrant parents on ...
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The New York Times
''The New York Times'' (''NYT'') is an American daily newspaper based in New York City. ''The New York Times'' covers domestic, national, and international news, and publishes opinion pieces, investigative reports, and reviews. As one of the longest-running newspapers in the United States, the ''Times'' serves as one of the country's Newspaper of record, newspapers of record. , ''The New York Times'' had 9.13 million total and 8.83 million online subscribers, both by significant margins the List of newspapers in the United States, highest numbers for any newspaper in the United States; the total also included 296,330 print subscribers, making the ''Times'' the second-largest newspaper by print circulation in the United States, following ''The Wall Street Journal'', also based in New York City. ''The New York Times'' is published by the New York Times Company; since 1896, the company has been chaired by the Ochs-Sulzberger family, whose current chairman and the paper's publ ...
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List Of Guggenheim Fellowships Awarded In 1949
One hundred and forty-four Guggenheim Fellowships were awarded in 1949. 1949 U.S. and Canadian Fellows 1949 Latin American and Caribbean Fellows See also * Guggenheim Fellowship * List of Guggenheim Fellowships awarded in 1948 * List of Guggenheim Fellowships awarded in 1950 References {{DEFAULTSORT:List Of Guggenheim Fellowships Awarded In 1949 1949 Events January * January 1 – A United Nations-sponsored ceasefire brings an end to the Indo-Pakistani War of 1947. The war results in a stalemate and the division of Kashmir, which still continues as of 2025 * January 2 – Luis ... Guggenheim Guggenheim ...
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Indiana University (Bloomington)
Indiana University Bloomington (IU Bloomington, Indiana University, IU, IUB, or Indiana) is a public research university in Bloomington, Indiana, United States. It is the flagship campus of Indiana University and its largest campus, with over 48,000 students. Established as the state's seminary in 1820, the name was changed to "Indiana College" in 1829 and to "Indiana University" in 1838. Indiana University is a member of the Association of American Universities and is classified among "R1: Doctoral Universities – Very high research activity". Its schools and programs include the Jacobs School of Music, Kelley School of Business, School of Education, Luddy School of Informatics, O'Neill School of Public and Environmental Affairs, School of Public Health, School of Medicine, School of Nursing, Hutton Honors College, The Media School, and Maurer School of Law. The campus also features the Lilly Library, Eskenazi Museum of Art, and the Indiana Memorial Union. Indi ...
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