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Innovative Genomics Institute
The Innovative Genomics Institute (IGI) is a nonprofit scientific research institute founded by Nobel laureate and CRISPR gene editing pioneer Jennifer Doudna and biophysicist Jonathan Weissman. The institute is based at the University of California, Berkeley, and also has member researchers at the University of California, San Francisco, UC Davis, UCLA, Lawrence Berkeley National Laboratory, Lawrence Livermore National Laboratory, Gladstone Institutes, and other collaborating research institutions. The IGI focuses on developing real-world applications of genome editing to address problems in human health, agriculture and climate change. In addition to Doudna, current IGI directors and investigators include Jillian Banfield, who first introduced Doudna to CRISPR systems in bacteria in 2006, Fyodor Urnov, who coined the term "genome editing" with colleagues in 2005, as well as Alex Marson, Brian Staskawicz, and Pamela Ronald. The current executive director is Bradley Ringeisen, form ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jennifer Doudna
Jennifer Anne Doudna (; born February 19, 1964) is an American biochemist who has done pioneering work in CRISPR gene editing, and made other fundamental contributions in biochemistry and genetics. Doudna was one of the first women to share a Nobel in the sciences. She received the 2020 Nobel Prize in Chemistry, with Emmanuelle Charpentier, "for the development of a method for genome editing." She is the Li Ka Shing Chancellor's Chair Professor in the Department of Chemistry and the Department of Molecular and Cell Biology at the University of California, Berkeley. She has been an investigator with the Howard Hughes Medical Institute since 1997. She graduated from Pomona College in 1985 and earned a Ph.D. from Harvard Medical School in 1989. Apart from her professorship at Berkeley, she is also president and chair of the board of the Innovative Genomics Institute, a faculty scientist at Lawrence Berkeley National Laboratory, a senior investigator at the Gladstone Institutes ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gladstone Institutes
Gladstone Institutes is an independent, non-profit biomedical research organization whose focus is to better understand, prevent, treat and cure cardiovascular, viral and neurological conditions such as heart failure, HIV/AIDS and Alzheimer's disease. Its researchers study these diseases using techniques of basic and translational science. Another focus at Gladstone is building on the development of induced pluripotent stem cell technology by one of its investigators, 2012 Nobel Laureate Shinya Yamanaka, to improve drug discovery, personalized medicine and tissue regeneration. Founded in 1979, Gladstone is academically affiliated with the University of California, San Francisco (UCSF), and located adjacent to UCSF's Mission Bay campus. The organization comprises five major institutes, as well as multiple centers focused on various areas of research. The current president of the institute is Deepak Srivastava. History Gladstone Institutes was founded in 1979 as a research an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Li Ka Shing Foundation
The Li Ka Shing Foundation () is a Hong Kong-based charitable organization founded in 1980 by Hong Kong entrepreneur Li Ka-shing. The Third Son Li Ka-shing considers the Li Ka Shing Foundation to be his "third son" and has pledged to donate one-third of his assets to support philanthropic projects. He has called for other Asian entrepreneurs to do the same, in the hope of altering the traditional notion of passing wealth through lineage. The Li Ka Shing Foundation's story stretches back over three decades: Having grown up as a witness to suffering and illness, Li Ka-shing cultivated a compassion that set in motion the idea of establishing a charitable foundation. Mission Li Ka Shing Foundation supports projects that promote social progress through expanding access to quality education and medical services and research, encouraging cultural diversity and community involvement. Every project and every donation stems from Li Ka-shing's belief in the inherent value of each hum ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jennifer Doudna In 2021 At The Innovative Genomics Institute 02
Jennifer or Jenifer may refer to: People *Jennifer (given name) * Jenifer (singer), French pop singer * Jennifer Warnes, American singer who formerly used the stage name Jennifer * Daniel of St. Thomas Jenifer * Daniel Jenifer Film and television * ''Jennifer'' (1953 film), a film starring Ida Lupino * ''Jennifer'' (1978 film), a horror film by Brice Mack * ''Jennifer'', a 1998 Ghanaian film starring Brew Riverson Jnr * "Jenifer" (''Masters of Horror''), an episode of ''Masters of Horror'' Music * The Jennifers, a British band, some of whose members later formed Supergrass * ''Jenifer'' (album), an album by French singer Jenifer * ''Jennifer'' (album), a 1972 album by Jennifer Warnes * "Jennifer", a 1974 song by Faust from ''Faust IV'' * "Jennifer", a 1983 song by Eurythmics from ''Sweet Dreams (Are Made of This)'' (album) * "Jennifer", a 2001 song by M2M from ''The Big Room'' Other uses * Hurricane Jennifer * Project Jennifer, a CIA attempt to recover a Soviet subm ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rare Disease
A rare disease is any disease that affects a small percentage of the population. In some parts of the world, an orphan disease is a rare disease whose rarity means there is a lack of a market large enough to gain support and resources for discovering treatments for it, except by the government granting economically advantageous conditions to creating and selling such treatments. Orphan drugs are ones so created or sold. Most rare diseases are genetic and thus are present throughout the person's entire life, even if symptoms do not immediately appear. Many rare diseases appear early in life, and about 30% of children with rare diseases will die before reaching their fifth birthdays. With only four diagnosed patients in 27 years, ribose-5-phosphate isomerase deficiency is considered the rarest known genetic disease. No single cut-off number has been agreed upon for which a disease is considered rare. A disease may be considered rare in one part of the world, or in a particular gr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
CRISPR Therapeutics
CRISPR Therapeutics AG is a Swiss–American biotechnology company headquartered in Zug, Switzerland. In fiscal year 2021, the company had revenues of $915 million, with net income of $378 million. By the end of the same year, the number of employees stood at 473. As of December 2021, the company had a market capitalization of over $6 billion. CRISPR Therapeutics' investors include German chemical company Bayer. The company operates R&D in Cambridge, Massachusetts. History CRISPR Therapeutics was founded in 2013 as Inception Genomics by Emmanuelle Charpentier, Shaun Foy and Rodger Novak. Charpentier later shared the Nobel Prize in Chemistry in 2020 with Jennifer Doudna. As part of a working group, she provided the first scientific documentation on the development and use of CRISPR gene editing. This allows DNA to be specifically modified and exchanged, which can for example prevent diseases. The company CRISPR Therapeutics is to apply this new technology commerc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Editas Medicine
Editas Medicine, Inc., (formerly Gengine, Inc.), is a clinical-stage biotechnology company which is developing therapies for rare diseases based on CRISPR gene editing technology. Editas headquarters is located in Cambridge, Massachusetts and has facilities in Boulder, Colorado. History Editas Medicine was originally founded with the name "Gengine, Inc." in September 2013 by Feng Zhang of the Broad Institute, Jennifer Doudna of the University of California, Berkeley, and George Church, David Liu, and J. Keith Joung of Harvard University, with funding from Third Rock Ventures, Polaris Partners and Flagship Ventures; the name was changed to the current "Editas Medicine" two months later. Doudna quit in June 2014 over legal differences concerning intellectual property of Cas9. In August 2015, the company raised $120 million in Series B funding from Bill Gates and 13 other investors. it went public on 2 February 2016, with an IPO that raised $94 million. The compan ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Caribou Biosciences
Rachel Elizabeth Haurwitz (born May 20, 1985) is an American biochemist and structural biologist. She is the co-founder, chief executive officer, and president of Caribou Biosciences, a genome editing company. Early life and education Haurwitz was born on May 20, 1985. She grew up in Austin, Texas, Austin, Texas. Her mother is an elementary school teacher and her father, an environmental journalist. Haurwitz began researching RNA during her undergraduate years. She attended Harvard College where she earned an undergraduate degree. In 2007, she began doctoral studies at University of California, Berkeley. At the age of 21, Haurwitz began working as a graduate student in Jennifer Doudna's laboratory, in 2008 where she completed her doctorate in molecular and cell biology. Haurwitz originally intended on becoming an intellectual property lawyer for biotechnology patents but later chose to continue in science. Career In 2011, Haurwitz and Doudna co-founded Caribou Biosciences, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nobel Prize In Chemistry
) , image = Nobel Prize.png , alt = A golden medallion with an embossed image of a bearded man facing left in profile. To the left of the man is the text "ALFR•" then "NOBEL", and on the right, the text (smaller) "NAT•" then "MDCCCXXXIII" above, followed by (smaller) "OB•" then "MDCCCXCVI" below. , awarded_for = Outstanding contributions in chemistry , presenter = Royal Swedish Academy of Sciences , location = Stockholm, Sweden , reward = 9 million SEK (2017) , year = 1901 , holder = Carolyn R. Bertozzi, Morten P. Meldal and Karl Barry Sharpless (2022) , most_awards = Frederick Sanger and Karl Barry Sharpless (2) , website nobelprize.org, previous = 2021 , year2=2022, main= 2022, next= 2023 The Nobel Prize in Chemistry is awarded annually by the Royal Swedish Academy of Sciences to scientists in the various fields of chemistry. It is one of the five Nobel Prizes established by the will of Alfred Nobel in 1895, award ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Emmanuelle Charpentier
Emmanuelle Marie Charpentier (; born 11 December 1968) is a French professor and researcher in microbiology, genetics, and biochemistry. As of 2015, she has been a director at the Max Planck Institute for Infection Biology in Berlin. In 2018, she founded an independent research institute, the Max Planck Unit for the Science of Pathogens. In 2020, Charpentier and American biochemist Jennifer Doudna of the University of California, Berkeley, were awarded the Nobel Prize in Chemistry "for the development of a method for genome editing" (through CRISPR). This was the first science Nobel Prize ever won by two women only. Early life and education Born in 1968 in Juvisy-sur-Orge in France, Charpentier studied biochemistry, microbiology, and genetics at the Pierre and Marie Curie University (today the Faculty of Science of Sorbonne University) in Paris. She was a graduate student at the Institut Pasteur from 1992 to 1995 and was awarded a research doctorate. Charpentier's PhD ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cas9
Cas9 (CRISPR associated protein 9, formerly called Cas5, Csn1, or Csx12) is a 160 kilodalton protein which plays a vital role in the immunological defense of certain bacteria against DNA viruses and plasmids, and is heavily utilized in genetic engineering applications. Its main function is to cut DNA and thereby alter a cell's genome. The CRISPR-Cas9 genome editing technique was a significant contributor to the Nobel Prize in Chemistry in 2020 being awarded to Emmanuelle Charpentier and Jennifer Doudna. More technically, Cas9 is a dual RNA-guided DNA endonuclease enzyme associated with the Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) adaptive immune system in ''Streptococcus pyogenes''. ''S. pyogenes'' utilizes CRISPR to memorize and Cas9 to later interrogate and cleave foreign DNA, such as invading bacteriophage DNA or plasmid DNA. Cas9 performs this interrogation by unwinding foreign DNA and checking for sites complementary to the 20 nucleotide spac ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
DARPA
The Defense Advanced Research Projects Agency (DARPA) is a research and development agency of the United States Department of Defense responsible for the development of emerging technologies for use by the military. Originally known as the Advanced Research Projects Agency (ARPA), the agency was created on February 7, 1958, by President Dwight D. Eisenhower in response to the Soviet launching of Sputnik 1 in 1957. By collaborating with academia, industry, and government partners, DARPA formulates and executes research and development projects to expand the frontiers of technology and science, often beyond immediate U.S. military requirements.Dwight D. Eisenhower and Science & Technology, (2008). Dwight D. Eisenhower Memorial CommissionSource '' The Economist'' has called DARPA the agency "that shaped the modern world," and pointed out that " Moderna's COVID-19 vaccine sits alongside weather satellites, GPS, drones, stealth technology, voice interfaces, the personal comput ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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