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Imbert-Fick Law
Armand Imbert (1850–1922) and Adolf Fick (1829–1901) both demonstrated, independently of each other, that in ocular tonometry the tension of the wall can be neutralized when the application of the tonometer produces a flat surface instead of a convex one, and the reading of the tonometer (P) then equals (T) the IOP," whence all forces cancel each other. This principle was used by Hans Goldmann (1899–1991) who referred to it as the Imbert-Fick "law", thus giving his newly marketed tonometer (with the help of the Haag-Streit Company) a quasi-scientific basis; it is mentioned in the ophthalmic and optometric literature, but not in any books of physics. According to Goldmann, "The law states that the pressure in a sphere filled with liquid and surrounded by an infinitely thin membrane is measured by the counterpressure which just flattens the membrane." "The law presupposes that the membrane is without thickness and without rigidity...practically without any extensibility." A ...
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Adolf Eugen Fick
Adolf Eugen Fick (3 September 1829 – 21 August 1901) was a German-born physician and physiologist. Early life and education Fick began his work in the formal study of mathematics and physics before realising an aptitude for medicine. He then earned his doctorate in medicine from the University of Marburg in 1851. As a fresh medical graduate, he began his work as a prosector.The Virtual Laboratory: Fick, Adolf Eugen
accessed 5 February 2006
He died in at age 71.


Career

In 1855, he introduced

Incompressible Flow
In fluid mechanics, or more generally continuum mechanics, incompressible flow is a flow in which the material density does not vary over time. Equivalently, the divergence of an incompressible flow velocity is zero. Under certain conditions, the flow of compressible fluids can be modelled as incompressible flow to a good approximation. Derivation The fundamental requirement for incompressible flow is that the density, \rho , is constant within a small element volume, ''dV'', which moves at the flow velocity u. Mathematically, this constraint implies that the material derivative (discussed below) of the density must vanish to ensure incompressible flow. Before introducing this constraint, we must apply the conservation of mass to generate the necessary relations. The mass is calculated by a volume integral of the density, \rho : : = . The conservation of mass requires that the time derivative of the mass inside a control volume be equal to the mass flux, J, acro ...
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Eye Examination
An eye examination, commonly known as an eye test, is a series of tests performed to assess Visual acuity, vision and ability to Focus (optics), focus on and discern objects. It also includes other tests and examinations of the human eye, eyes. Eye examinations are primarily performed by an optometrist, ophthalmologist, or an orthoptist. Health care professionals often recommend that all people should have periodic and thorough eye examinations as part of routine primary care, especially since many eye diseases are asymptomatic. Typically, a healthy individual who otherwise has no concerns with their eyes receives an eye exam once in their 20s and twice in their 30s. Eye examinations may detect potentially treatable blindness, blinding eye diseases, ocular manifestation of systemic disease, ocular manifestations of systemic disease, or signs of tumour, tumors or other anomalies of the Human brain, brain. A full eye examination consists of a comprehensive evaluation of medical h ...
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Elastic Deformation
In engineering, deformation (the change in size or shape of an object) may be ''elastic'' or ''plastic''. If the deformation is negligible, the object is said to be ''rigid''. Main concepts Occurrence of deformation in engineering applications is based on the following background concepts: * ''Displacements'' are any change in position of a point on the object, including whole-body translations and rotations ( rigid transformations). * ''Deformation'' are changes in the relative position between internals points on the object, excluding rigid transformations, causing the body to change shape or size. * ''Strain'' is the ''relative'' ''internal'' deformation, the dimensionless change in shape of an infinitesimal cube of material relative to a reference configuration. Mechanical strains are caused by mechanical stress, ''see stress-strain curve''. The relationship between stress and strain is generally linear and reversible up until the yield point and the deformation is ...
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Cornea
The cornea is the transparency (optics), transparent front part of the eyeball which covers the Iris (anatomy), iris, pupil, and Anterior chamber of eyeball, anterior chamber. Along with the anterior chamber and Lens (anatomy), lens, the cornea Refraction, refracts light, accounting for approximately two-thirds of the eye's total optical power. In humans, the refractive power of the cornea is approximately 43 dioptres. The cornea can be reshaped by surgical procedures such as LASIK. While the cornea contributes most of the eye's focusing power, its Focus (optics), focus is fixed. Accommodation (eye), Accommodation (the refocusing of light to better view near objects) is accomplished by changing the geometry of the lens. Medical terms related to the cornea often start with the prefix "''wikt:kerat-, kerat-''" from the Ancient Greek, Greek word κέρας, ''horn''. Structure The cornea has myelinated, unmyelinated nerve endings sensitive to touch, temperature and chemicals; a to ...
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Newton's Third Law Of Motion
Newton's laws of motion are three physical laws that describe the relationship between the motion of an object and the forces acting on it. These laws, which provide the basis for Newtonian mechanics, can be paraphrased as follows: # A body remains at rest, or in motion at a constant speed in a straight line, unless it is acted upon by a force. # At any instant of time, the net force on a body is equal to the body's acceleration multiplied by its mass or, equivalently, the rate at which the body's momentum is changing with time. # If two bodies exert forces on each other, these forces have the same magnitude but opposite directions. The three laws of motion were first stated by Isaac Newton in his '' Philosophiæ Naturalis Principia Mathematica'' (''Mathematical Principles of Natural Philosophy''), originally published in 1687. Newton used them to investigate and explain the motion of many physical objects and systems. In the time since Newton, new insights, especially aroun ...
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Surface Area
The surface area (symbol ''A'') of a solid object is a measure of the total area that the surface of the object occupies. The mathematical definition of surface area in the presence of curved surfaces is considerably more involved than the definition of arc length of one-dimensional curves, or of the surface area for polyhedra (i.e., objects with flat polygonal faces), for which the surface area is the sum of the areas of its faces. Smooth surfaces, such as a sphere, are assigned surface area using their representation as parametric surfaces. This definition of surface area is based on methods of infinitesimal calculus and involves partial derivatives and double integration. A general definition of surface area was sought by Henri Lebesgue and Hermann Minkowski at the turn of the twentieth century. Their work led to the development of geometric measure theory, which studies various notions of surface area for irregular objects of any dimension. An important example is ...
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Deformation (engineering)
In engineering, deformation (the change in size or shape of an object) may be ''elastic'' or ''plastic''. If the deformation is negligible, the object is said to be ''rigid''. Main concepts Occurrence of deformation in engineering applications is based on the following background concepts: * ''Displacements'' are any change in position of a point on the object, including whole-body translations and rotations ( rigid transformations). * ''Deformation'' are changes in the relative position between internals points on the object, excluding rigid transformations, causing the body to change shape or size. * ''Strain'' is the ''relative'' ''internal'' deformation, the dimensionless change in shape of an infinitesimal cube of material relative to a reference configuration. Mechanical strains are caused by mechanical stress, ''see stress-strain curve''. The relationship between stress and strain is generally linear and reversible up until the yield point and the deformation is ...
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Sphere
A sphere (from Ancient Greek, Greek , ) is a surface (mathematics), surface analogous to the circle, a curve. In solid geometry, a sphere is the Locus (mathematics), set of points that are all at the same distance from a given point in three-dimensional space.. That given point is the center (geometry), ''center'' of the sphere, and the distance is the sphere's ''radius''. The earliest known mentions of spheres appear in the work of the Greek mathematics, ancient Greek mathematicians. The sphere is a fundamental surface in many fields of mathematics. Spheres and nearly-spherical shapes also appear in nature and industry. Bubble (physics), Bubbles such as soap bubbles take a spherical shape in equilibrium. The Earth is spherical Earth, often approximated as a sphere in geography, and the celestial sphere is an important concept in astronomy. Manufactured items including pressure vessels and most curved mirrors and lenses are based on spheres. Spheres rolling, roll smoothly in ...
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Ocular Tonometry
Tonometry is the procedure that eye care professionals perform to determine the intraocular pressure (IOP), the fluid pressure inside the eye. It is an important test in the evaluation of patients at risk from glaucoma. Most tonometers are calibrated to measure pressure in millimeters of mercury (mmHg), with the normal eye pressure range between . Methods Applanation tonometry In applanation tonometry the intraocular pressure (IOP) is inferred from the force required to flatten (applanate) a constant area of the cornea, for the Imbert-Fick law. The Maklakoff tonometer was an early example of this method, while the Goldmann tonometer is the most widely used version in current practice. Because the probe makes contact with the cornea, a topical anesthetic, such as proxymetacaine, is introduced on to the surface of the eye in the form of an eye drop. Goldmann tonometry Goldmann applanation tonometry (GAT) is considered to be the gold standard IOP test and is the most widely ...
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Stiffness
Stiffness is the extent to which an object resists deformation in response to an applied force. The complementary concept is flexibility or pliability: the more flexible an object is, the less stiff it is. Calculations The stiffness, k, of a body is a measure of the resistance offered by an elastic body to deformation. For an elastic body with a single degree of freedom (DOF) (for example, stretching or compression of a rod), the stiffness is defined as k = \frac where, * F is the force on the body * \delta is the displacement produced by the force along the same degree of freedom (for instance, the change in length of a stretched spring) Stiffness is usually defined under quasi-static conditions, but sometimes under dynamic loading. In the International System of Units, stiffness is typically measured in newtons per meter (N/m). In Imperial units, stiffness is typically measured in pounds (lbs) per inch. Generally speaking, deflections (or motions) of an infinitesima ...
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Biological Membrane
A biological membrane, biomembrane or cell membrane is a selectively permeable membrane that separates the interior of a cell from the external environment or creates intracellular compartments by serving as a boundary between one part of the cell and another. Biological membranes, in the form of eukaryotic cell membranes, consist of a phospholipid bilayer with embedded, integral and peripheral proteins used in communication and transportation of chemicals and ions. The bulk of lipids in a cell membrane provides a fluid matrix for proteins to rotate and laterally diffuse for physiological functioning. Proteins are adapted to high membrane fluidity environment of the lipid bilayer with the presence of an annular lipid shell, consisting of lipid molecules bound tightly to the surface of integral membrane proteins. The cell membranes are different from the isolating tissues formed by layers of cells, such as mucous membranes, basement membranes, and serous membranes. ...
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