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ISET Test
The ISET Test (Isolation by SizE of Tumor cells / Trophoblastic cells) is a diagnostic test, diagnostic blood test that detects circulating tumor cells in a blood sample. The test uses an Medical test#By method, in-vitro diagnostic system developed at INSERM, the Université Paris Descartes and Assistance Publique–Hôpitaux de Paris in order to isolate cancer cells from blood without loss and identify them through a diagnostic cytopathology-based approach. __TOC__ Operation A 1-milliliter, ml sample of blood will typically contain 5 to 10 million leukocytes, 5 billion erythrocytes, and a small number of circulating rare cells, including: * non-tumor cells such as epithelial-normal cells, epithelial-atypical cells, endothelial vells and stem cells; * physiological state-dependent cells such as fetal cells in pregnant and ex-pregnant women; * circulating tumor cells (CTCs) which are of diagnostic value in diagnosing various cancers. The diagnostic problem is to find and identify ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Blood
Blood is a body fluid in the circulatory system of humans and other vertebrates that delivers necessary substances such as nutrients and oxygen to the cells, and transports metabolic waste products away from those same cells. Blood is composed of blood cells suspended in blood plasma. Plasma, which constitutes 55% of blood fluid, is mostly water (92% by volume), and contains proteins, glucose, mineral ions, and hormones. The blood cells are mainly red blood cells (erythrocytes), white blood cells (leukocytes), and (in mammals) platelets (thrombocytes). The most abundant cells are red blood cells. These contain hemoglobin, which facilitates oxygen transport by reversibly binding to it, increasing its solubility. Jawed vertebrates have an adaptive immune system, based largely on white blood cells. White blood cells help to resist infections and parasites. Platelets are important in the clotting of blood. Blood is circulated around the body through blood vessels by the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Université Paris Descartes
Paris Descartes University (), also known as Paris V, was a French public university A public university, state university, or public college is a university or college that is State ownership, owned by the state or receives significant funding from a government. Whether a national university is considered public varies from o ... located in Paris. It was one of the inheritors of the historic University of Paris, which was split into 13 universities in 1970. Paris Descartes completely merged with Paris Diderot University in 2019 to form a new Université Paris Cité, Paris Cité University. It was established as a multidisciplinary university "of humanities and health sciences" ("''des Sciences de l’Homme et de la Santé''". It focused on the areas of medical sciences, biomedical sciences, law, computer science, social sciences, economics and psychology. Its main campus was in the historic École de Chirurgie in the 6th arrondissement of Paris. History The historic Univ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Patrizia Paterlini-Bréchot
Patrizia Paterlini-Bréchot, born in the Italian city of Reggio Emilia, is an Italian scientist and a professor of cell biology and oncology working at the Faculté de Médecine Necker-Enfants Malades, Université Paris Descartes and at INSERM in Paris. Education Patrizia Paterlini-Bréchot studied medicine at the University of Modena and Reggio Emilia, Italy. In 1978, she defended a thesis on Hodgkin's Lymphoma, which was awarded the title of ''« Best medical thesis »'' of the year 1978. She pursued her training and validated a double specialization in Hematology (1981), awarded the prize of ''« Best research in Hematology »'' of the year 1979, and in Oncology (1984). Patrizia Paterlini-Bréchot obtained a permanent academic position in the University of L'Aquila (1981), then Bologna (1984) working in the departments of Hematology, Gastroenterology and Oncology. In 1988 she moved to Paris (France) for a training in molecular biology in professor Christian Bréchot's laborat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Figure 2, Tumor And Non Tumor Cells Are Present In Blood
Figure may refer to: General *A shape, drawing, depiction, or geometric configuration *Figure (wood), wood appearance *Figure (music), distinguished from musical motif *Noise figure, in telecommunication *Dance figure, an elementary dance pattern *A person's figure, human physical appearance *Figure–ground (perception), the distinction between a visually perceived object and its surroundings Arts *Figurine, a miniature statuette representation of a creature *Action figure, a posable jointed solid plastic character figurine *Figure painting, realistic representation, especially of the human form *Figure drawing *Model figure, a scale model of a creature Writing *figure, in writing, a type of floating block (text, table, or graphic separate from the main text) *Figure of speech, also called a rhetorical figure *Christ figure, a type of character * in typesetting, text figures and lining figures Accounting *Figure, a synonym for number *Significant figures in a decimal number ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cytopathology
Cytopathology (from Greek , ''kytos'', "a hollow"; , ''pathos'', "fate, harm"; and , ''-logia'') is a branch of pathology that studies and diagnoses diseases on the cellular level. The discipline was founded by George Nicolas Papanicolaou in 1928. Cytopathology is generally used on samples of free cells or tissue fragments, in contrast to histopathology, which studies whole tissues. Cytopathology is frequently, less precisely, called "cytology", which means "the study of cells". Cytopathology is commonly used to investigate diseases involving a wide range of body sites, often to aid in the diagnosis of cancer but also in the diagnosis of some infectious diseases and other inflammatory conditions. For example, a common application of cytopathology is the Pap smear, a screening tool used to detect precancerous cervical lesions that may lead to cervical cancer. Cytopathologic tests are sometimes called smear tests because the samples may be smeared across a glass microscop ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Erythrocyte
Red blood cells (RBCs), referred to as erythrocytes (, with -''cyte'' translated as 'cell' in modern usage) in academia and medical publishing, also known as red cells, erythroid cells, and rarely haematids, are the most common type of blood cell and the vertebrate's principal means of delivering oxygen () to the body tissues—via blood flow through the circulatory system. Erythrocytes take up oxygen in the lungs, or in fish the gills, and release it into tissues while squeezing through the body's capillaries. The cytoplasm of a red blood cell is rich in hemoglobin (Hb), an iron-containing biomolecule that can bind oxygen and is responsible for the red color of the cells and the blood. Each human red blood cell contains approximately 270 million hemoglobin molecules. The cell membrane is composed of proteins and lipids, and this structure provides properties essential for physiological cell function such as deformability and stability of the blood cell while traversing ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Leukocyte
White blood cells (scientific name leukocytes), also called immune cells or immunocytes, are cells of the immune system that are involved in protecting the body against both infectious disease and foreign entities. White blood cells are generally larger than red blood cells. They include three main subtypes: granulocytes, lymphocytes and monocytes. All white blood cells are produced and derived from multipotent cells in the bone marrow known as hematopoietic stem cells. Leukocytes are found throughout the body, including the blood and lymphatic system. All white blood cells have nuclei, which distinguishes them from the other blood cells, the anucleated red blood cells (RBCs) and platelets. The different white blood cells are usually classified by cell lineage ( myeloid cells or lymphoid cells). White blood cells are part of the body's immune system. They help the body fight infection and other diseases. Types of white blood cells are granulocytes (neutrophils, eosinoph ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Milliliter
The litre (Commonwealth English, Commonwealth spelling) or liter (American English, American spelling) (SI symbols L and l, other symbol used: ℓ) is a metric units, metric unit of volume. It is equal to 1 cubic decimetre (dm3), 1000 cubic centimetres (cm3) or 0.001 cubic metres (m3). A cubic decimetre (or litre) occupies a volume of (see figure) and is thus equal to one-thousandth of a cubic metre. The original French metric system used the litre as a SI base unit, base unit. The word ''litre'' is derived from an older French unit, the ''Units of measurement in France before the French Revolution#Volume – Dry measures, litron'', whose name came from Byzantine Greek language, Greek—where it was a unit of weight, not volume—via Late Medieval Latin, and which equalled approximately 0.831 litres. The litre was also used in several subsequent versions of the metric system and is accepted for use with the SI, despite it not being an International System of Units, SI un ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Assistance Publique–Hôpitaux De Paris
Greater Paris University Hospitals ( , AP-HP) is the university hospital trust operating in Paris and its surroundings. It is the largest hospital system in Europe and one of the largest in the world. It employs more than 90,000 people in 38 teaching hospitals and receives more than 10 million annual patient visits. AP-HP is organized in 6 hospital local trusts called "GHU", each associated to a university to offer integrative care to its population. It is affiliated with Paris Cité University (16 teaching hospitals), Sorbonne University (7 teaching hospitals), Saclay University (6 teaching hospitals), the University of Créteil (5 teaching hospitals), Sorbonne Paris North University (3 teaching hospitals) and their colleges of medicine, odontology, and pharmacy. As a teaching hospitals network, AP-HP trust is in charge of training healthcare professionals and doctors, and plays a prominent role in French healthcare research alongside Inserm. History Succeeding to the ''con ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Medical Test
A medical test is a medical procedure performed to detect, diagnose, or monitor diseases, disease processes, susceptibility, or to determine a course of treatment. Medical tests such as, physical and visual exams, diagnostic imaging, genetic testing, chemical and cellular analysis, relating to clinical chemistry and molecular diagnostics, are typically performed in a medical setting. Types of tests By purpose Medical tests can be classified by their purposes, including diagnosis, screening or monitoring. Diagnostic A diagnostic test is a procedure performed to confirm or determine the presence of disease in an individual suspected of having a disease, usually following the report of symptoms, or based on other medical test results. This includes posthumous diagnosis. Examples of such tests are: * Using nuclear medicine to examine a patient suspected of having a lymphoma. * Measuring the blood sugar in a person suspected of having diabetes mellitus after periods of in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tumor Cells
A neoplasm () is a type of abnormal and excessive growth of tissue. The process that occurs to form or produce a neoplasm is called neoplasia. The growth of a neoplasm is uncoordinated with that of the normal surrounding tissue, and persists in growing abnormally, even if the original trigger is removed. This abnormal growth usually forms a mass, which may be called a tumour or tumor.'' ICD-10 classifies neoplasms into four main groups: benign neoplasms, in situ neoplasms, malignant neoplasms, and neoplasms of uncertain or unknown behavior. Malignant neoplasms are also simply known as cancers and are the focus of oncology. Prior to the abnormal growth of tissue, such as neoplasia, cells often undergo an abnormal pattern of growth, such as metaplasia or dysplasia. However, metaplasia or dysplasia does not always progress to neoplasia and can occur in other conditions as well. The word neoplasm is from Ancient Greek 'new' and 'formation, creation'. Types A neoplasm ca ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
