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IL-5
IL 5 or IL-5 may refer to: * Interleukin 5 Interleukin 5 (IL5) is an interleukin produced by type-2 T helper cells and mast cells. Function Through binding to the interleukin-5 receptor, interleukin 5 stimulates B cell growth and increases immunoglobulin secretion - primarily IgA. It ... * Illinois's 5th congressional district * Illinois Route 5 {{Letter-NumberCombDisambig ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Interleukin 5
Interleukin 5 (IL5) is an interleukin produced by type-2 T helper cells and mast cells. Function Through binding to the interleukin-5 receptor, interleukin 5 stimulates B cell growth and increases immunoglobulin secretion - primarily IgA. It is also a key mediator in eosinophil activation. Structure IL-5 is a 115-amino acid (in human, 133 in the mouse) -long TH2 cytokine that is part of the hematopoietic family. Unlike other members of this cytokine family (namely interleukin 3 and GM-CSF), this glycoprotein in its active form is a homodimer. Tissue expression The IL-5 gene is located on chromosome 11 in the mouse, and chromosome 5 in humans, in close proximity to the genes encoding IL-3, IL-4, and granulocyte-macrophage colony-stimulating factor ( GM-CSF), which are often co-expressed in TH2 cells. Interleukin-5 is also expressed by eosinophils and has been observed in the mast cells of asthmatic airways by immunohistochemistry. IL-5 expression is regulated by se ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Illinois's 5th Congressional District
The 5th congressional district of Illinois covers parts of Cook and DuPage counties, as of the 2011 redistricting which followed the 2010 census. All or parts of Chicago, Elmhurst, Elmwood Park, Franklin Park, Hinsdale, La Grange Park, Norridge, Northlake, River Grove, Schiller Park, and Oakbrook Terrace are included. It has been represented by Democrat Mike Quigley since the April 2009 special election. History The district was created as part of the 28th United States Congress, which first met on March 4, 1843; it was initially represented by Stephen A. Douglas, whose Kansas–Nebraska Act prompted the creation of the Republican Party. Since the 1990s redistricting, it has covered most of Chicago's North Side; the 2010 redistricting extended it into DuPage County. It was represented by Democrat Rahm Emanuel from January 2003 until he resigned on January 2, 2009, to become White House Chief of Staff. On April 8, 2009, Mike Quigley won a special election t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
