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IARC Group 3
IARC group 3 substances, chemical mixtures and exposure circumstances are those that can not be classified in regard to their carcinogenicity to humans by the International Agency for Research on Cancer (IARC). This category is used most commonly for agents, mixtures and exposure circumstances for which the level of evidence of carcinogenicity is inadequate in humans and inadequate or limited in experimental animals. Exceptionally, agents (mixtures) for which the evidence of carcinogenicity is inadequate in humans, but sufficient in experimental animals may be placed in this category when there is strong evidence that the mechanism of carcinogenicity in experimental animals does not operate in humans. Agents, mixtures and exposure circumstances that do not fall into any other group are also placed in this category. The IARC Monographs on which this list is based assess the hazard linked to the agents, they do not assess the cancer risk of the agents. The list is up-to-date as of J ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chemical Mixture
In chemistry, a mixture is a material made up of two or more different chemical substances which can be separated by physical method. It is an impure substance made up of 2 or more elements or compounds mechanically mixed together in any proportion. A mixture is the physical combination of two or more substances in which the identities are retained and are mixed in the form of Solution (chemistry), solutions, Suspension (chemistry), suspensions or colloids. Mixtures are one product of mechanically blending or mixing chemical substances such as chemical element, elements and Compound (chemistry), compounds, without chemical bonding or other chemical change, so that each ingredient substance retains its own chemical properties and makeup. Despite the fact that there are no chemical changes to its constituents, the physical properties of a mixture, such as its melting point, may differ from those of the components. Some mixtures can be separation process, separated into their compone ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Aldrin
Aldrin is an organochlorine insecticide that was widely used until the 1990s, when it was banned in most countries. Aldrin is a member of the so-called "classic organochlorines" (COC) group of pesticides. COCs enjoyed a very sharp rise in popularity during and after World War II. Other noteworthy examples of COCs include dieldrin and DDT. After research showed that organochlorines can be highly toxic to the ecosystem through bioaccumulation, most were banned from use. Before the ban, it was heavily used as a pesticide to treat seed and soil. Aldrin and related "cyclodiene" pesticides (a term for pesticides derived from Hexachlorocyclopentadiene) became notorious as persistent organic pollutants.Robert L. Metcalf "Insect Control" in Ullmann’s Encyclopedia of Industrial Chemistry" Wiley-VCH, Weinheim, 2002. Structure and Reactivity Pure aldrin takes form as a white crystalline powder. Though it is not soluble in water (0.003% solubility), aldrin dissolves very well in organic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
11-Aminoundecanoic Acid
11-Aminoundecanoic acid is an organic compound with the formula H2N(CH2)10CO2H. This white solid is classified as an amine and a fatty acid. 11-Aminoundecanoic acid is a precursor to Nylon-11. Production As practiced by Arkema, 11-aminoundecanoic acid is prepared industrially from undecylenic acid, which is derived from castor oil. The synthesis proceeds in four separate reactions: Transesterification of castor oil to methyl ricinoleate Crude castor oil consists of about 80% triglycerides, from the ricinoleic acid, itself representing about 90% of the oil. It is quantitatively transesterified with methanol to methyl ricinoleate (the methyl ester of ricinoleic acid) in the presence of the basic sodium methoxide at 80 °C within 1 h reaction time in a stirred reactor. At the end of the reaction, the resulting glycerol separates and the liquid methyl ester is washed with water to remove residual glycerol. : Pyrolysis of methylricinoleate to heptanal and methyl undecenoate Me ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1-Amino-2-methylanthraquinone
Disperse dye is a category of synthetic dye intended for polyester and related hydrophobic fibers. Disperse dyes are polar molecules containing anthraquinone or azo groups. It is estimated that 85% of disperse dyes are azos or anthraquinone dyes. History The history of disperse dye production is closely related to the synthesis of cellulose acetate fibres. Disperse dyes were invented in 1923-24. Fundamentals of dyeing Disperse dyes are non-ionic in nature and partially soluble in water. The interaction of dye molecule and polymer takes place with Van der Waals and dipole forces. Disperse dyes have better diffusion at boiling to a higher temperature. Examples * Disperse Blue dyes, especially 106 and 124, are common causes of contact allergy. * Disperse Orange 1 is an azo dye. * Disperse Red 9 is a red dye derived from anthraquinone. * Disperse Red 11, also called C.I. 62015 and 1,4-diamino-2-methoxy anthraquinone, is another anthraquinone dye. * Disperse Red 60 is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Para-Aminobenzoic Acid
4-Aminobenzoic acid (also known as ''para''-aminobenzoic acid or PABA because the two functional groups are attached to the benzene ring across from one another in the ''para'' position) is an organic compound with the formula H2NC6H4CO2H. PABA is a white crystalline solid, although commercial samples can appear gray. It is slightly soluble in water. It consists of a benzene ring substituted with amino and carboxyl groups. The compound occurs extensively in the natural world. Production and occurrence In industry, PABA is prepared mainly by two routes: * Reduction of 4-nitrobenzoic acid * Hoffman degradation of the monoamide derived from terephthalic acid. Food sources of PABA include liver, brewer's yeast (and unfiltered beer), kidney, molasses, mushrooms, and whole grains. Other food sources of PABA include spinach, liver, and oat seeds. Biology Biochemistry PABA is an intermediate in the synthesis of folate by bacteria, plants, and fungi. Many bacteria, including ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Amaranth (dye)
Amaranth, FD&C Red No. 2, E123, C.I. Food Red 9, Acid Red 27, Azorubin S, or C.I. 16185 is a modified red azo dye used as a food dye and to color cosmetics. The name was taken from amaranth grain, a plant distinguished by its red color and edible protein-rich seeds. Amaranth is an anionic dye. It can be applied to natural and synthetic fibers, leather, paper, and phenol-formaldehyde resins. As a food additive it has E number E123. Amaranth usually comes as a trisodium salt. It has the appearance of reddish-brown, dark red to purple water-soluble powder that decomposes at 120 °C without melting. Its water solution has an absorption maximum of about 520 nm. Like all azo dyes, Amaranth was, during the middle of the 20th century, made from coal tar; modern synthetics are more likely to be made from petroleum byproducts. Since 1976, amaranth dye has been banned in the United States by the Food and Drug Administration (FDA) as a suspected carcinogen. Its use i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
