Human Pheromones
No study has led to the isolation of true human sex pheromones, although various researchers have investigated the possibility of their existence. Pheromones, in general, are secreted chemical substances by organisms that trigger a social reaction in the same species. Sex pheromones are a special type of olfactory signal, produced to attract the opposite sex, to encourage mating or to perform some other function closely related to sexual reproduction. While humans are highly dependent upon visual cues, smells can also play a role in sociosexual behaviors. An inherent difficulty in studying human pheromones is the need for cleanliness and odorlessness in human participants. Experiments have focused on three classes of putative human sex pheromones: axillary steroids, vaginal aliphatic acids and stimulators of the vomeronasal organ. Axillary steroids are produced by the testicles, ovaries, apocrine glands and adrenal glands. These chemicals are not biologically active until ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Androstadienol
Androstadienol, or androsta-5,16-dien-3β-ol, is a 16-androstene class endogenous steroid, pheromone, and chemical intermediate to several other pheromones that is found in the sweat of both men and women. Androstadienol and androstadienone are odorless compounds secreted by the apocrine glands, and via conversion into the more powerfully-odorous androstenone and androstenol (catalyzed by aerobic corynebacteria, particularly ''Corynebacterium xerosis'', in men, and '' Micrococcaceae spp.'' in women), are considered to be mainly responsible for the "musky" component of axillary (underarm) odor. Androstadienol is synthesized from pregnenolone by the 16-ene-synthetase activity of CYP17A1, and is converted into androstadienone by 3β-hydroxysteroid dehydrogenase. Male sweat contains approximately five times as much androstenone as does female sweat, which can be explained by sex differences in androstadienol and androstadienone production. Androstadienone, which is prod ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Body Odour And Sexual Attraction
Odour is sensory stimulation of the olfactory membrane of the nose by a group of molecules. Certain body odor, body odours are connected to human sexual attraction. Humans can make use of body odour subconsciously to identify whether a potential mate will pass on favourable traits to their offspring. Body odour may provide significant cues about the genetic quality, health and reproductive success of a potential mate. Body odour affects sexual attraction in a number of ways including through human biology, the menstrual cycle and fluctuating asymmetry. The olfactory membrane plays a role in smelling and subconsciously assessing another human's pheromones. It also affects the sexual attraction of insects and mammals. The major histocompatibility complex genes are important for the immune system, and appear to play a role in sexual attraction via body odour. Studies have shown that body odour is strongly connected with attraction in heterosexual females. The women in one study ranke ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Vox (website)
''Vox'' () is an American news and opinion website owned by Vox Media. The website was founded in April 2014 by Ezra Klein, Matt Yglesias, and Melissa Bell (journalist), Melissa Bell, and is noted for its concept of explanatory journalism. Vox's media presence also includes a YouTube channel, several podcasts, and a show presented on Netflix. ''Vox'' has been described as left-leaning and Liberalism in the United States, liberal. History Prior to founding ''Vox'', Ezra Klein worked for ''The Washington Post'' as the head of Wonkblog, a public policy blog. When Klein attempted to launch a new site using funding from the newspaper's editors, his proposal was turned down and Klein subsequently left ''The Washington Post'' for a position with Vox Media, another communications company, in January 2014. ''The New York Times'' David Carr (journalist), David Carr associated Klein's exit for ''Vox'' with other "big-name journalists" leaving newspapers for digital start-ups, such as ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Martha McClintock
Martha Kent McClintock (born February 22, 1947) is an American psychologist best known for her research on human pheromones and her theory of menstrual synchrony. Her research focuses on the relationship that the environment and biology have upon sexual behaviour. She is the David Lee Shillinglaw Distinguished Service Professor in Psychology at the University of Chicago and is the Founder and past Director of the Institute for Mind and Biology. Education and career McClintock was born in Pasadena, California, and obtained her bachelor's degree from Wellesley College in 1969. She received a PhD from the University of Pennsylvania and joined the Department of Psychology at the University of Chicago in 1976. She also holds faculty appointments in the Department of Comparative Human Development, the Committee on Evolutionary Biology, and the Committee on Neurobiology. She is a member of the American Academy of Arts and Sciences, the Institute of Medicine in the National Academy o ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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McClintock Effect
Menstrual synchrony, also called the McClintock effect, or the Wellesley effect, is a contested process whereby women who begin living together in close proximity would experience their menstrual cycle onsets (the onset of menstruation or menses) becoming more synchronized together in time than when previously living apart. "For example, the distribution of onsets of seven female lifeguards was scattered at the beginning of the summer, but after 3 months spent together, the onset of all seven cycles fell within a 4-day period." Martha McClintock's 1971 paper, published in ''Nature (journal), Nature'', says that menstrual cycle synchronization happens when the menstrual cycle onsets of two or more women become closer together in time than they were several months earlier. After the initial studies, several papers were published reporting methodological flaws in studies reporting menstrual synchrony, including McClintock's study. In addition, other studies were published that failed ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Menstrual Cycle
The menstrual cycle is a series of natural changes in hormone production and the structures of the uterus and ovaries of the female reproductive system that makes pregnancy possible. The ovarian cycle controls the production and release of eggs and the cyclic release of estrogen and progesterone. The uterine cycle governs the preparation and maintenance of the lining of the uterus (womb) to receive an embryo. These cycles are concurrent and coordinated, normally last between 21 and 35 days, with a median length of 28 days. Menarche (the onset of the first period) usually occurs around the age of 12 years; menstrual cycles continue for about 30–45 years. Naturally occurring hormones drive the cycles; the cyclical rise and fall of the follicle stimulating hormone prompts the production and growth of oocytes (immature egg cells). The hormone estrogen stimulates the uterus lining ( endometrium) to thicken to accommodate an embryo should fertilization occur. The blood suppl ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Androsterone
Androsterone, or 3α-hydroxy-5α-androstan-17-one, is an endogenous steroid hormone, neurosteroid, and putative pheromone. It is a weak androgen with a potency that is approximately 1/7 that of testosterone. Androsterone is a metabolite of testosterone and dihydrotestosterone (DHT). In addition, it can be converted back into DHT via 3α-hydroxysteroid dehydrogenase and 17β-hydroxysteroid dehydrogenase, bypassing conventional intermediates such as androstanedione and testosterone, and as such, can be considered to be a metabolic intermediate in its own right. Androsterone is also known to be an inhibitory androstane neurosteroid, acting as a positive allosteric modulator of the GABAA receptor, and possesses anticonvulsant effects. The unnatural enantiomer of androsterone is more potent as a positive allosteric modulator of GABAA receptors and as an anticonvulsant than the natural form. Androsterone's 3β-isomer is epiandrosterone, and its 5β- epimer is etiocholanol ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Androstenol
Androstenol, also known as 5α-androst-16-en-3α-ol (shortened to 3α,5α-androstenol or 3α-androstenol), is a 16-androstene class steroidal pheromone and neurosteroid in humans and other mammals, notably pigs. It possesses a characteristic musk-like odor. Androstenol, or a derivative, is found in black truffles. This was offered as an explanation for how pigs locate them deep in the ground: Androstenol is produced in the saliva of male pigs. However, experiments in France using pigs to scent truffles, truffle scent extract, and purified androstenol showed that pigs responded to the first two (actually trying to eat dirt containing the truffle extract), but ignored the androstenol. A stereoisomer of androstenol, 3β-androstenol (5α-androst-16-en-3β-ol), is also endogenous to humans (as well as to pigs), behaving as a pheromone and contributing to axillary odor. Biosynthesis In humans and boars, androstenol is biosynthesized in the testes. Pregnenolone is metabolized into ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Androstenone
Androstenone (5α-androst-16-en-3-one) is a 16-androstene class steroidal pheromone. It is found in boar's saliva, celery cytoplasm, and truffle fungus. Androstenone was the first mammalian pheromone to be identified. It is found in high concentrations in the saliva of male pigs, and, when inhaled by a female pig that is in heat, results in the female assuming the mating stance. Androstenone is the active ingredient in 'Boarmate', a commercial product made by DuPont sold to pig farmers to test sows for timing of artificial insemination. Biosynthesis Androstenone is synthesized from androstadienone by 5α-reductase, and can be converted into 3α-androstenol or 3β-androstenol by 3-ketosteroid reductase. Properties Depending upon the subject, androstenone can have an unpleasant, sweaty, urinous smell, a woody smell, or even a pleasant floral smell. There are two different genotypes that allow an individual to smell androstenone. The first genotype, which consists of two ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Androstadienone
Androstadienone, or androsta-4,16-dien-3-one, is a 16-androstene class endogenous steroid that has been described as having potent pheromone-like activities in humans. The compound is synthesized from androstadienol by 3β-hydroxysteroid dehydrogenase, and can be converted into androstenone (a more potent and odorous pheromone) by 5α-reductase, which can subsequently be converted into 3α-androstenol or 3β-androstenol (also more potent and odorous pheromones) by 3-ketosteroid reductase. Androstadienone is related to the androgen sex hormones; however, androstadienone does not exhibit any androgenic or anabolic effects. Though it has been reported to significantly affect the mood of heterosexual Heterosexuality is romantic attraction, sexual attraction, or sexual behavior between people of the opposite sex or gender. As a sexual orientation, heterosexuality is "an enduring pattern of emotional, romantic, and/or sexual attractions ... women and homosexual men, ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Adrenal Gland
The adrenal glands (also known as suprarenal glands) are endocrine glands that produce a variety of hormones including adrenaline and the steroids aldosterone and cortisol. They are found above the kidneys. Each gland has an outer adrenal cortex, cortex which produces steroid hormones and an inner Adrenal medulla, medulla. The adrenal cortex itself is divided into three main zones: the zona glomerulosa, the zona fasciculata and the zona reticularis. The adrenal cortex produces three main types of steroid hormones: mineralocorticoids, glucocorticoids, and androgens. Mineralocorticoids (such as aldosterone) produced in the zona glomerulosa help in the regulation of blood pressure and osmoregulation, electrolyte balance. The glucocorticoids cortisol and cortisone are synthesized in the zona fasciculata; their functions include the regulation of metabolism and immune system suppression. The innermost layer of the cortex, the zona reticularis, produces androgens that are converted to ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |