Howard Martin Temin
Howard Martin Temin (December 10, 1934 – February 9, 1994) was an American geneticist and virologist. He discovered reverse transcriptase in the 1970s at the University of Wisconsin–Madison, for which he shared the 1975 Nobel Prize in Physiology or Medicine with Renato Dulbecco and David Baltimore. Early life and education Temin was born in Philadelphia, Pennsylvania, to Jewish parents, Annette (Lehman), an activist, and Henry Temin, an attorney.Harman, Oren S., and Michael R. Dietrich. Rebels, Mavericks, and Heretics in Biology. New Haven: Yale UP, 2009. Print. As a high school student at Central High School in Philadelphia, he participated in the Jackson Laboratory's Summer Student Program in Bar Harbor, Maine. The director of the program, C.C. Little, told his parents that Temin was "unquestionably the finest scientist of the fifty-seven students who have attended the program since the beginning...I can't help but feel this boy is destined to become a really great m ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Philadelphia, Pennsylvania
Philadelphia ( ), colloquially referred to as Philly, is the List of municipalities in Pennsylvania, most populous city in the U.S. state of Pennsylvania and the List of United States cities by population, sixth-most populous city in the United States, with a population of 1,603,797 in the 2020 United States census, 2020 census. The city is the urban core of the Philadelphia metropolitan area (sometimes called the Delaware Valley), the nation's Metropolitan statistical area, seventh-largest metropolitan area and ninth-largest combined statistical area with 6.245 million residents and 7.379 million residents, respectively. Philadelphia was founded in 1682 by William Penn, an English Americans, English Quakers, Quaker and advocate of Freedom of religion, religious freedom, and served as the capital of the Colonial history of the United States, colonial era Province of Pennsylvania. It then played a historic and vital role during the American Revolution and American Revolutionary ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Renato Dulbecco
Renato Dulbecco ( , ; February 22, 1914 – February 19, 2012) was an Italian–American virologist who won the 1975 Nobel Prize in Physiology or Medicine for his work on oncoviruses, which are viruses that can cause cancer when they infect animal cells. He studied at the University of Turin under Giuseppe Levi, along with fellow students Salvador Luria and Rita Levi-Montalcini, who also moved to the U.S. with him and won Nobel prizes. He was drafted into the Italian army in World War II, but later joined the resistance. Early life Dulbecco was born in Catanzaro (Calabria, Southern Italy), but spent his childhood and grew up in Liguria, in the coastal city Imperia. He graduated from high school at 16, then moved to the University of Turin. Despite a strong interest in mathematics and physics, he decided to study medicine. At only 22, he graduated in morbid anatomy and pathology under the supervision of professor Giuseppe Levi. During these years he met Salvador Luria and Rit ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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McArdle Laboratory For Cancer Research
The McArdle Laboratory for Cancer Research is a basic cancer research facility located on the University of Wisconsin–Madison campus in Madison, Wisconsin. It houses the university's Department of Oncology . The staff of the McArdle Laboratory numbers approximately 200. Twenty-eight faculty members lead research groups focused on various fields such as cancer virology, signal transduction, cell cycle, cancer genetics, and carcinogenesis. Peer-reviewed grants awarded on a competitive basis by agencies such as the National Cancer Institute, Department of Defense, American Cancer Society, and Susan G. Komen for the Cure provide the major source of research funds for the McArdle Laboratory. A small percentage of McArdle’s operating budget is provided by the State of Wisconsin. Private donations and bequests made directly to the McArdle Laboratory play a vital role in the support of the research carried out at the Laboratory. Founding faculty Harold P. Rusch, Roswell Boutwell ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Harry Rubin (biologist)
Harry Rubin (born June 23, 1926, in New York City) – February 2, 2020) was an American cell biologist and virologist. He is known for his experimental research on oncoviruses and how cellular microenvironment and cellular aging affect the regulation of cancerous tumors. Biography His parents were Jewish immigrants and his father had a grocery store and delicatessen in Manhattan. Harry Rubin graduated in 1947 as a Doctor of Veterinary Medicine (D.V.M.) from the New York State College of Veterinary Medicine at Cornell University. From 1947 to 1948 he served in the joint U.S.-Mexican Aftosa Commission dealing with an outbreak of hoof-and-mouth disease (''fiebre aftosa'' in Spanish) among cattle in Mexico. From 1948 to 1952 he was stationed in Montgomery, Alabama as a commissioned officer of the United States Public Health Service. In January 1952 he married Dorothy Margaret Shuster, who was being trained as a flight evacuation nurse in the U.S. Air Force when he met her. In 1952 he ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Embryology
Embryology (from Ancient Greek, Greek ἔμβρυον, ''embryon'', "the unborn, embryo"; and -λογία, ''-logy, -logia'') is the branch of animal biology that studies the Prenatal development (biology), prenatal development of gametes (sex cells), fertilization, and development of embryos and fetuses. Additionally, embryology encompasses the study of congenital disorders that occur before birth, known as teratology. Early embryology was proposed by Marcello Malpighi, and known as preformationism, the theory that organisms develop from pre-existing miniature versions of themselves. Aristotle proposed the theory that is now accepted, Epigenesis (biology), epigenesis. Epigenesis (biology), Epigenesis is the idea that organisms develop from seed or egg in a sequence of steps. Modern embryology developed from the work of Karl Ernst von Baer, though accurate observations had been made in Italy by anatomists such as Aldrovandi and Leonardo da Vinci in the Renaissance. Comparative ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Animal Virology
Veterinary virology is the study of viruses in non-human animals. It is an important branch of veterinary medicine. Rhabdoviruses Rhabdoviruses are a diverse family of single stranded, negative sense RNA viruses that infect a wide range of hosts, from plants and insects, to fish and mammals. The ''Rhaboviridae'' family consists of six genera, two of which, cytorhabdoviruses and nucleorhabdoviruses, only infect plants. Novirhabdoviruses infect fish, and vesiculovirus, lyssavirus and ephemerovirus infect mammals, fish and invertebrates. The family includes pathogens such as rabies virus, vesicular stomatitis virus and potato yellow dwarf virus that are of public health, veterinary, and agricultural significance. Foot-and-mouth disease virus Foot-and-mouth disease virus (FMDV) is a member of the Aphthovirus genus in the Picornaviridae family and is the cause of foot-and-mouth disease in pigs, cattle, sheep and goats. It is a non-enveloped, positive strand, RNA virus. FMDV i ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Biology
Biology is the scientific study of life and living organisms. It is a broad natural science that encompasses a wide range of fields and unifying principles that explain the structure, function, growth, History of life, origin, evolution, and distribution of life. Central to biology are five fundamental themes: the cell (biology), cell as the basic unit of life, genes and heredity as the basis of inheritance, evolution as the driver of biological diversity, energy transformation for sustaining life processes, and the maintenance of internal stability (homeostasis). Biology examines life across multiple biological organisation, levels of organization, from molecules and cells to organisms, populations, and ecosystems. Subdisciplines include molecular biology, physiology, ecology, evolutionary biology, developmental biology, and systematics, among others. Each of these fields applies a range of methods to investigate biological phenomena, including scientific method, observation, ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Bar Mitzvah
A ''bar mitzvah'' () or ''bat mitzvah'' () is a coming of age ritual in Judaism. According to Halakha, Jewish law, before children reach a certain age, the parents are responsible for their child's actions. Once Jewish children reach that age, they are said to "become" ''b'nai mitzvah'', at which point they begin to be held accountable for their own actions. Traditionally, the father of a ''bar'' or ''bat mitzvah'' offers thanks to God that he is no longer punished for his child's Jewish views on sin, sins. In Orthodox Judaism, Orthodox communities, boys become ''bar mitzvah'' at 13 and girls become ''bat mitzvah'' at 12. In most Reform Judaism, Reform, Reconstructionist Judaism, Reconstructionist, and Conservative Judaism, Conservative communities, the milestone is 13 regardless of gender. After this point, children are also held responsible for knowing Jewish law, Jewish ritual law, Jewish tradition, tradition, and Jewish ethics, ethics, and are able to participate in all ar ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Bar Harbor, Maine
Bar Harbor () is a resort town on Mount Desert Island in Hancock County, Maine, United States. As of the 2020 census, its population is 5,089. The town is home to the College of the Atlantic, Jackson Laboratory, and MDI Biological Laboratory. During summer and fall seasons, it is a popular tourist destination. Bar Harbor is also home to the largest parts of Acadia National Park, including Cadillac Mountain, the highest point within of the coastline of the Eastern United States. From the mainland, Bar Harbor is accessible by road via Maine State Route 3. The island is directly accessible by air at Hancock County–Bar Harbor Airport, and by ferry from Winter Harbor, Maine, and Yarmouth, Nova Scotia. History The town of Bar Harbor was founded on the northeast shore of Mount Desert Island, which the Wabanaki Indians knew as ''Pemetic'', meaning "range of mountains" or "mountains seen at a distance." The Wabanaki seasonally fish, hunt and gather berries, clams, ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Jackson Laboratory
The Jackson Laboratory (often abbreviated as JAX) is an independent, non-profit biomedical research institution which was founded by Clarence Cook Little in 1929. It employs over 3,000 employees in Bar Harbor, Maine; Sacramento, California; Farmington, Connecticut; Shanghai, China; and Yokohama, Japan. The institution is a National Cancer Institute-designated Cancer Center and has NIH Centers of Excellence in aging and systems genetics. The stated mission of The Jackson Laboratory is "to discover the genetic basis for preventing, treating and curing human diseases, and to enable research and education for the global biomedical community." The laboratory also provides more than 13,000 strains of mouse models to more than 2,400 organizations in 68 countries around the world. Additionally, JAX is the home of the Mouse Genome Informatics database, and an international hub for scientific courses, conferences, training and education. Major research areas The Jackson Laboratory ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |