Hartmut Beug
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Hartmut Beug
Hartmut Beug (1945–2011) was a German cancer biologist who studied how groups of oncogenes interact to lead to the development and spread of cancer. Shortly before his death, a foundation was set up in his and his wife’s name to support collaboration among young scientists and their studies in the field of metastasis. Early life and education Hartmut Beug was born in Hamburg, Germany in 1945, and raised there. From 1964 to 1971, he studied biology at the University of Freiburg. From 1971 to 1973, he studied the protist Dictyostelium in the frame of his PhD studies in Günther Gerisch’s lab at the Friedrich-Miescher-Laboratorium of the Max Planck Society in Tübingen. Career and research From 1973 to 1978, Hartmut Beug was a postdoctoral researcher at the Max Planck Institut für Virusforschung (today’s Max Planck Institute for Developmental Biology) in the lab of Thomas Graf in Tübingen. Beug followed Thomas Graf to the Deutsches Krebsforschungszentrum (DKFZ) in ...
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Max Planck Institute For Developmental Biology
Max or MAX may refer to: Animals * Max (American dog) (1983–2013), at one time purported to be the world's oldest living dog * Max (British dog), the first pet dog to win the PDSA Order of Merit (animal equivalent of the OBE) * Max (gorilla) (1971–2004), a western lowland gorilla at the Johannesburg Zoo who was shot by a criminal in 1997 Brands and enterprises * Australian Max Beer * Max Hamburgers, a fast-food corporation * MAX Index, a Hungarian domestic government bond index * Max Fashion, an Indian clothing brand Computing * MAX (operating system), a Spanish-language Linux version * Max (software), a music programming language * MAX Machine * Multimedia Acceleration eXtensions, extensions for HP PA-RISC Films * ''Max'' (1994 film), a Canadian film by Charles Wilkinson * ''Max'' (2002 film), a film about Adolf Hitler * ''Max'' (2015 film), an American war drama film * ''Max'' (2024 film), an Indian Kannada language film by Vijay Karthikeyaa Games * '' Dancing Stag ...
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Heidelberg
Heidelberg (; ; ) is the List of cities in Baden-Württemberg by population, fifth-largest city in the States of Germany, German state of Baden-Württemberg, and with a population of about 163,000, of which roughly a quarter consists of students, it is List of cities in Germany by population, Germany's 51st-largest city. Located about south of Frankfurt, Heidelberg is part of the densely populated Rhine-Neckar, Rhine-Neckar Metropolitan Region which has its centre in Mannheim. Heidelberg is located on the Neckar River, at the point where it leaves its narrow valley between the Oden Forest and the Kleiner Odenwald, Little Oden Forest, and enters the wide Upper Rhine Plain. The old town lies in the valley, the end of which is flanked by the Königstuhl (Odenwald), Königstuhl in the south and the Heiligenberg (Heidelberg), Heiligenberg in the north. The majority of the population lives in the districts west of the mountains in the Upper Rhine Plain, into which the city has expan ...
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2011 Deaths
This is a list of lists of deaths of notable people, organized by year. New deaths articles are added to their respective month (e.g., Deaths in ) and then linked below. 2025 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990 1989 1988 1987 1986 Earlier years ''Deaths in years earlier than this can usually be found in the main articles of the years.'' See also * Lists of deaths by day * Deaths by year (category) {{DEFAULTSORT:deaths by year ...
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1945 Births
1945 marked the end of World War II, the fall of Nazi Germany, and the Empire of Japan. It is also the year concentration camps were liberated and the only year in which atomic weapons have been used in combat. Events World War II will be abbreviated as “WWII” January * January 1 – WWII: ** Germany begins Operation Bodenplatte, an attempt by the ''Luftwaffe'' to cripple Allied air forces in the Low Countries. ** Chenogne massacre: German prisoners are allegedly killed by American forces near the village of Chenogne, Belgium. * January 6 – WWII: A German offensive recaptures Esztergom, Hungary from the Soviets. * January 9 – WWII: American and Australian troops land at Lingayen Gulf on western coast of the largest Philippine island of Luzon, occupied by Japan since 1942. * January 12 – WWII: The Soviet Union begins the Vistula–Oder Offensive in Eastern Europe, against the German Army. * January 13 – WWII: The Soviet Union begins the East Prussia ...
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Breast Cancer
Breast cancer is a cancer that develops from breast tissue. Signs of breast cancer may include a Breast lump, lump in the breast, a change in breast shape, dimpling of the skin, Milk-rejection sign, milk rejection, fluid coming from the nipple, a newly inverted nipple, or a red or scaly patch of skin. In those with Metastatic breast cancer, distant spread of the disease, there may be bone pain, swollen lymph nodes, shortness of breath, or yellow skin. Risk factors for developing breast cancer include obesity, a Sedentary lifestyle, lack of physical exercise, alcohol consumption, hormone replacement therapy during menopause, ionizing radiation, an early age at Menarche, first menstruation, having children late in life (or not at all), older age, having a prior history of breast cancer, and a family history of breast cancer. About five to ten percent of cases are the result of an inherited genetic predisposition, including BRCA mutation, ''BRCA'' mutations among others. Breast ...
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Hematopoietic Stem Cell
Hematopoietic stem cells (HSCs) are the stem cells that give rise to other blood cells. This process is called haematopoiesis. In vertebrates, the first definitive HSCs arise from the ventral endothelial wall of the embryonic aorta within the (midgestational) aorta-gonad-mesonephros region, through a process known as endothelial-to-hematopoietic transition. In adults, haematopoiesis occurs in the red bone marrow, in the core of most bones. The red bone marrow is derived from the layer of the embryo called the mesoderm. Haematopoiesis is the process by which all mature blood cells are produced. It must balance enormous production needs (the average person produces more than 500 billion blood cells every day) with the need to regulate the number of each blood cell type in the circulation. In vertebrates, the vast majority of hematopoiesis occurs in the bone marrow and is derived from a limited number of hematopoietic stem cells that are multipotent and capable of extensive ...
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Progenitor Cell
A progenitor cell is a biological cell that can differentiate into a specific cell type. Stem cells and progenitor cells have this ability in common. However, stem cells are less specified than progenitor cells. Progenitor cells can only differentiate into their "target" cell type. The most important difference between stem cells and progenitor cells is that stem cells can replicate indefinitely, whereas progenitor cells can divide only a limited number of times. Controversy about the exact definition remains and the concept is still evolving. The terms "progenitor cell" and "stem cell" are sometimes equated. Properties Most progenitors are identified as oligopotent. In this point of view, they can compare to adult stem cells, but progenitors are said to be in a further stage of cell differentiation. They are "midway" between stem cells and fully differentiated cells. The kind of potency they have depends on the type of their "parent" stem cell and also on their niche. Some ...
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Oncogene
An oncogene is a gene that has the potential to cause cancer. In tumor cells, these genes are often mutated, or expressed at high levels.Kimball's Biology Pages.
"Oncogenes" Free full text
Most normal cells undergo a preprogrammed rapid cell death () if critical functions are altered and then malfunction. Activated oncogenes can cause those cells designated for apoptosis to survive and proliferate instead. Most oncogenes began as proto-oncogenes: normal genes involved in cell growth and proliferation or inhibition of apoptosis. If, through mutation, normal genes promoting cellular growth are up-regulated (gain-of-function mutation), they predispose the cel ...
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University Of Veterinary Medicine Vienna
The University of Veterinary Medicine Vienna (German: ''Veterinärmedizinische Universität Wien'' - in short: VUW) was founded in 1767 as the world's third school for veterinary medicine (after Lyon and Alfort) by Milan Milan ( , , ; ) is a city in northern Italy, regional capital of Lombardy, the largest city in Italy by urban area and the List of cities in Italy, second-most-populous city proper in Italy after Rome. The city proper has a population of nea ...'s Ludovico Scotti, originally named ''k. k. Pferde-Curen- und Operationsschule'' (literally, "Imperial-Royal School for the Cure and Surgery of Horses"). Today, it has c. 2,800 students and c. 600 employees. Spin-offs Since 2002, universities in Austria can found spin-off companies. Most of the spin-off companies are still located on the university's grounds: Animal Health IT, Biomodels Austria, Innovaphyt, Marinomed, Mycosafe, Novelix, VetWIDI, VirBiomed, ViruSure The university also operates the Teaching an ...
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University Of Vienna
The University of Vienna (, ) is a public university, public research university in Vienna, Austria. Founded by Rudolf IV, Duke of Austria, Duke Rudolph IV in 1365, it is the oldest university in the German-speaking world and among the largest institutions of higher learning in Europe. The university is associated with 17 List of Nobel laureates, Nobel Prize winners and has been the home to many scholars of historical and academic importance. History Middle Ages to the Enlightenment The university was founded on March 12, 1365, by Rudolf IV, Duke of Austria, hence the name "Alma Mater Rudolphina". After the Charles University in Prague (1347) and Jagiellonian University in Kraków (1364), the University of Vienna is the third oldest university in Central Europe and the oldest university in the contemporary German-speaking world; it remains a question of definition as the Charles University in Prague was German-speaking when founded, too. However, Pope Urban V did not ratify th ...
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Mariano Barbacid
Mariano Barbacid Montalbán (born 4 October 1949 in Madrid) is a Spanish molecular biochemist who discovered the first oncogene HRAS. Academic career He completed his higher education in the Universidad Complutense de Madrid, where he studied chemical sciences, and in the United States, where he started as an intern; years later he was appointed director of the National Cancer Institute. He then moved back to his native Spain to lead the newly created CNIO (Centro Nacional de Investigaciones Oncológicas). He also served on the Life Sciences jury for the Infosys Prize in 2011. Scientific Research Barbacid is credited for isolating the human oncogene HRAS in bladder carcinoma. His discovery was published in ''Nature'' in 1982 in an article titled "A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder-carcinoma oncogene".Reddy EP, Reynolds RK, Santos E, Barbacid M«A point mutation is responsible for the acquisition of trans ...
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European Molecular Biology Organisation
The European Molecular Biology Organization (EMBO) is a professional, non-profit organization of more than 2,100 life scientists. Its goal is to promote research in life science and enable international exchange between scientists. It co-funds courses, workshops and conferences, publishes five scientific journals and supports individual scientists. The organization was founded in 1964 and is a founding member of the Initiative for Science in Europe. the Director of EMBO is Fiona Watt, a stem cell researcher, professor at King's College London and a group leader at the European Molecular Biology Laboratory. __TOC__ Conferences and journals In recent years, EMBO has funded more than 80 meetings with more than 12,000 participants each year. EMBO publishes five peer-reviewed scientific journals: ''The EMBO Journal'', ''EMBO Reports'', ''Molecular Systems Biology'', ''EMBO Molecular Medicine'', and ''Life Science Alliance''. History The European Molecular Biology Organization (EM ...
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