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Harold Hodge
Harold Carpenter Hodge (1904–1990) was a well-known toxicologist who published close to 300 papers and five books. He was the first president of the Society of Toxicology in 1960. He received a BS from Illinois Wesleyan University and a PhD in 1930 from the State University of Iowa, publishing his first paper in 1927. He received a number of honors and awards during his career. In 1931 he went to the School of Medicine and Dentistry at the University of Rochester in New York where he pursued his interest in toxicology, which included researching fluoride and dental fluorosis. At that time, the government and medical associations were invested in fluoride removal from water supplies because of the incidence of dental fluorosis in communities with high levels of naturally occurring calcium fluoride, and the adverse health impacts from industrial air pollution involving fluoride. Hodge was chosen to head the United States Atomic Energy Commission's (AEC) Division of Pharmacology an ...
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Opposition To Water Fluoridation
Opposition to the addition of fluoride to drinking water arises from political, ethical, economic, and health considerations. International and national agencies and dental associations across the world support the safety and effectiveness of water fluoridation. Proponents see it as a question of public health policy and equate the issue to vaccination and food fortification, citing significant benefits to dental health and minimal risks. * * In contrast, opponents view it as an infringement of individual rights, if not an outright violation of medical ethics, on the basis that individuals have no choice in the water that they drink, unless they drink more expensive bottled water. A small minority of scientists have challenged the medical consensus, variously claiming that water fluoridation has no or little cariostatic benefits, may cause serious health problems, is not effective enough to justify the costs, and is pharmacologically obsolete. Opposition to fluoridation has e ...
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American Toxicologists
American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, people who self-identify their ancestry as "American" ** American English, the set of varieties of the English language native to the United States ** Native Americans in the United States, indigenous peoples of the United States * American, something of, from, or related to the Americas, also known as "America" ** Indigenous peoples of the Americas * American (word), for analysis and history of the meanings in various contexts Organizations * American Airlines, U.S.-based airline headquartered in Fort Worth, Texas * American Athletic Conference, an American college athletic conference * American Recordings (record label), a record label that was previously known as Def American * American University, in Washington, D.C. Sports teams S ...
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Ruth Faden
Ruth R. Faden is an American scientist, academic, and founder of the Johns Hopkins Berman Institute of Bioethics. She was the Berman Institute's Director from 1995 until 2016, and the inaugural Andreas C. Dracopoulos Director from 2014 to 2016. Faden is the inaugural Philip Franklin Wagley Professor of Biomedical Ethics. Faden is a member of the Institute of Medicine and a Fellow of The Hastings Center and the American Psychological Association. She has served on President Clinton's Advisory Committee on Human Radiation Experiments, which she chaired. Faden co-launched the Global Food Ethics and Policy Program, sponsor of the 7 by 5 Agenda for Ethics and Global Food Security. She is also a co-founder of the Hinxton Group, a global community committed to advancing ethical and policy challenges in stem cell science, and the Second Wave initiative, an effort to ensure that the health interests of pregnant women are fairly represented in biomedical research and drug and device pol ...
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Acres Of Skin
''Acres of Skin: Human Experiments at Holmesburg Prison'' is a 1998 book by Allen Hornblum. The book documents clinical non-therapeutic Research Involving Prisoners, medical experiments on prison inmates at Holmesburg Prison in Philadelphia from 1951 to 1974, conducted under the direction of dermatologist Albert Kligman. The title of the book is a reference to Kligman's reaction on seeing hundreds of prisoners when he entered the prison: "All I saw before me were acres of skin"; "It was like a farmer seeing a fertile field for the first time". The book discusses issues surrounding the inadequate consent procedures of the 1950s and 1960s when using prisoners. Prisoners, attracted by the compensation, were angry when two of the experiment's participants testified before Congress. The publication of ''Acres of Skin'' in 1998 attracted considerable international media interest. The book has been reviewed in several journals including the ''International Journal of Dermatology'', ''S ...
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Experimentation On Prisoners
Throughout history, prisoners have been frequent participants in scientific, medical and social human subject research. Some of the research involving prisoners has been exploitative and cruel. Many of the modern protections for human subjects evolved in response to the abuses in prisoner research. Research involving prisoners is still conducted today, but prisoners are now one of the most highly protected groups of human subjects Requirements of research involving prisoners According to the Common Rule (45 CFR 46), prisoners may only be included in human subjects research when the research involves no more than a minimal risk of harm. Prisoner consent Prisoners cannot consent. Their status as imprisoned human subjects becomes even more ethically problematic when investigators offer incentives such as parole, phone calls, or objects that are normally unavailable to prisoners. Historical abuses Ancient history Herophilos of Chalcedon was reputed by Celcus, among others, to have vi ...
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Sodium Monofluorophosphate
Sodium monofluorophosphate, commonly abbreviated SMFP, is an inorganic compound with the chemical formula Na2PO3F. Typical for a salt, SMFP is odourless, colourless, and water-soluble. This salt is an ingredient in some toothpastes.Klaus Schrödter, Gerhard Bettermann, Thomas Staffel, Friedrich Wahl, Thomas Klein, Thomas Hofmann "Phosphoric Acid and Phosphates" in ''Ullmann’s Encyclopedia of Industrial Chemistry'' 2008, Wiley-VCH, Weinheim. Uses SMFP is best known as an ingredient in some toothpastes.Wolfgang Weinert "Oral Hygiene Products" in ''Ullmann’s Encyclopedia of Industrial Chemistry'' 2000, Wiley-VCH, Weinheim. It functions as a source of fluoride via the following hydrolysis reaction: :PO3F2− + OH− → HPO42− + F− Fluoride protects tooth enamel from attack by bacteria that cause dental caries (cavities). Although developed by a chemist at Procter and Gamble, its use in toothpaste ( Colgate toothpaste and Ultra Brite) was patented by Colgate-Palmo ...
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Unethical Human Experimentation In The United States
Numerous experiments which were performed on human test subjects in the United States in the past are now considered to have been unethical, because they were performed without the knowledge or informed consent of the test subjects. Such tests have been performed throughout American history, but have become significantly less frequent with the advent and adoption of various safeguarding efforts. Despite these safeguards, unethical experimentation involving human subjects is still occasionally uncovered. Past examples of unethical experiments include the exposure of humans to chemical and biological weapons (including infections with deadly or debilitating diseases), human radiation experiments, injections of toxic and radioactive chemicals, surgical experiments, interrogation and torture experiments, tests which involve mind-altering substances, and a wide variety of other experiments. Many of these tests are performed on children, the sick, and mentally disabled individuals, ...
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Western Reserve University
Western may refer to: Places *Western, Nebraska, a village in the US * Western, New York, a town in the US * Western Creek, Tasmania, a locality in Australia * Western Junction, Tasmania, a locality in Australia *Western world, countries that identify with shared "Western" culture *Western United States, a region of the United States Arts and entertainment Films * ''Western'' (1997 film), a French road movie directed by Manuel Poirier * ''Western'' (2017 film), a German-Austrian film Genres *Western (genre), a category of fiction and visual art centered on the American Old West ** Western fiction, the Western genre as featured in literature **Western film, the western genre in film **Western music (North America), a type of American folk music Music * ''Westerns'' (EP), an EP by Pete Yorn * WSTRN, a British hip hop group from west London *"Western" a song by Black Midi from '' Schlagenheim'' Business * The Western, a closed hotel/casino in Las Vegas, United States * Wester ...
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Illinois Wesleyan University
Illinois Wesleyan University is a private liberal arts college in Bloomington, Illinois, United States. Founded in 1850, the central portion of the present campus was acquired in 1854 with the first building erected in 1856. History The institution was founded in 1850 as a private four-year college in Bloomington, Illinois. The university's first international students, Y. Osawa and K. Tanaka, arrived from Japan in 1889. Illinois Wesleyan's College of Liberal Arts was formally organized in 1906, and the College of Fine Arts – combining schools of art, music, and theatre arts – was established in 1948. Illinois Wesleyan offered nursing study in conjunction with the Brokaw School of Nursing beginning in 1923, and in 1959 established the IWU School of Nursing with a four-year baccalaureate program. IWU operated a School of Law from 1873 to 1928. The institution's board of trustees took formal action to invite black students to enroll at Illinois Wesleyan in 1867 and wo ...
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American Dental Association
The American Dental Association (ADA) is an American professional dental association. Established in 1859 and with over 159,000 current members, ADA is the world's largest and oldest national dental association. The organization lobbies on behalf of the American dental profession and provides dental accreditation. The ADA publishes the '' Journal of the American Dental Association'' and ''JADA Foundational Science''. As part of its lobbying efforts, the ADA has sought to restrict non-dentists (such as dental hygienists and dental therapists) from providing basic dental care. The organization has played an important role in blocking the inclusion of dental coverage in Medicare. The ADA has expressed opposition to the opening of new dental schools or to increasing the number of dentists in the United States, even as the United States trains almost half as many dental students (relative to population) in the 2000s as it did in the 1980s. History The American Dental Associati ...
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American Society For Pharmacology And Experimental Therapeutics
The American Society for Pharmacology and Experimental Therapeutics (ASPET) is a scientific society founded in late 1908 by John Jacob Abel of Johns Hopkins University (also the founder of the American Society for Biochemistry and Molecular Biology), with the aim of promoting the growth of pharmacological research. Many society members are researchers in basic and clinical pharmacology who help develop disease-fighting medications and therapeutics. ASPET is one of the constituent societies of the Federation of American Societies for Experimental Biology (FASEB). The society's headquarters are in Rockville, MD. The current president is Michael F. Jarvis. Publications The society publishes three research journals and a review journal: the '' Journal of Pharmacology and Experimental Therapeutics'', '' Drug Metabolism and Disposition'', '' Molecular Pharmacology'', and ''Pharmacological Reviews'' Starting in 2012 these publications are only offered online. The society copublishes a ...
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