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Hallucinogenic Snuff
A hallucinogenic snuff, or psychedelic snuff, is a powder prepared from plants containing psychedelic alkaloids and insufflated (snorted) to produce hallucinogenic effects. Hallucinogenic snuffs have been used as entheogens by indigenous peoples of South and Central America for thousands of years. The snuffs are prepared most commonly from ''Anadenanthera'' species including ''Anadenanthera peregrina'' and ''Anadenanthera colubrina'', but also from species of other genuses including '' Mimosa'' and '' Virola''. They have local names including cohoba, ebene, paricá, yopo, cébil, and vilca, among many others. The active compounds in these snuffs include the serotonergic psychedelics bufotenin (5-HO-DMT), dimethyltryptamine (DMT), and 5-MeO-DMT. The materials of snuffs may also be used as enemas instead of via insufflation. Although previously thought to be non-hallucinogenic and/or toxic, ethnobotanist Jonathan Ott and colleagues showed in 2001 that bufotenin is an acti ...
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Modern Yopo Snuff
Modern may refer to: History *Modern history ** Early Modern period ** Late Modern period *** 18th century *** 19th century *** 20th century ** Contemporary history * Moderns, a faction of Freemasonry that existed in the 18th century Philosophy and sociology * Modernity, a loosely defined concept delineating a number of societal, economic and ideological features that contrast with "pre-modern" times or societies ** Late modernity Art * Modernism ** Modernist poetry * Modern art, a form of art * Modern dance, a dance form developed in the early 20th century * Modern architecture, a broad movement and period in architectural history ** Moderne, multiple architectural styles ** Modernisme a.k.a. Catalan Modernism * Modern music (other) Geography *Modra, a Slovak city, referred to in the German language as "Modern" Typography * Modern (typeface), a raster font packaged with Windows XP * Another name for the typeface classification known as Didone (typography) * Modern, a ...
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Cohoba
Cohoba is a Taíno transliteration for a ceremony in which the ground seeds of the ''cojóbana'' tree (''Anadenanthera'' spp.) were used as a hallucinogenic snuff, snuff via a Y-shaped snuff tray, snuff tube. Use of this substance produced a hallucinogenic or entheogenic effect. The ''cojóbana'' tree is believed by some to be ''Anadenanthera peregrina'' although it may have been a generalized term for hallucinogens, psychotropics, including the quite toxic ''Datura'' and related genera (Solanaceae). The corresponding ceremony using ''cohoba''-laced tobacco is transliterated as ''cojibá''. This was said to have produced the sense of a visionary journey of the kind associated with the practice of shamanism. The practice of snuffing ''cohoba'' was popular with the Taíno people, Taíno and Arawakan peoples, with whom Christopher Columbus made contact. However, the use of ''Anadenanthera'' Anadenanthera, spp. powder was widespread in South America, being used in ancient times by th ...
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Adverse Effect
An adverse effect is an undesired harmful effect resulting from a medication or other intervention, such as surgery. An adverse effect may be termed a "side effect", when judged to be secondary to a main or therapeutic effect. The term complication is similar to adverse effect, but the latter is typically used in pharmacological contexts, or when the negative effect is expected or common. If the negative effect results from an unsuitable or incorrect dosage or procedure, this is called a medical error and not an adverse effect. Adverse effects are sometimes referred to as " iatrogenic" because they are generated by a physician/treatment. Some adverse effects occur only when starting, increasing or discontinuing a treatment. Using a drug or other medical intervention which is contraindicated may increase the risk of adverse effects. Adverse effects may cause complications of a disease or procedure and negatively affect its prognosis. They may also lead to non-compliance wi ...
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Jonathan Ott
Jonathan Ott (born 1949 in Hartford, Connecticut) is an ethnobotanist, writer, translator, publisher, natural products chemist and botanical researcher in the area of entheogens and their cultural and historical uses, and helped coin the term "''entheogen''". Writings Ott has written eight books, co-written five, and contributed to four others, and published many articles in the field of entheogens. His comprehensive 1993 book, ''Pharmacotheon: Entheogenic Drugs, Their Plant Sources and History'' has been described as one of the important works on the subject of entheogenic drugs. It describes over 1,000 plants and chemical compounds. He has collaborated with other researchers like Christian Rätsch, Jochen Gartz, and the late ethnomycologist R. Gordon Wasson. He translated Albert Hofmann's 1979 book ''LSD: My Problem Child'' (''LSD: Mein Sorgenkind''), and ''On Aztec Botanical Names'' by Blas Pablo Reko, into English. His articles have appeared in many publications, includ ...
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Ethnobotanist
Ethnobotany is an interdisciplinary field at the interface of natural and social sciences that studies the relationships between humans and plants. It focuses on traditional knowledge of how plants are used, managed, and perceived in human societies. Ethnobotany integrates knowledge from botany, anthropology, ecology, and chemistry to study plant-related customs across cultures. Researchers in this field document and analyze how different societies use local flora for various purposes, including medicine, food, religious use, intoxicants, building materials, fuels and clothing. Richard Evans Schultes, often referred to as the "father of ethnobotany", provided an early definition of the discipline: Since Schultes' time, ethnobotany has evolved from primarily documenting traditional plant knowledge to applying this information in modern contexts, particularly in pharmaceutical development. The field now addresses complex issues such as intellectual property rights and equitable ben ...
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Toxicity
Toxicity is the degree to which a chemical substance or a particular mixture of substances can damage an organism. Toxicity can refer to the effect on a whole organism, such as an animal, bacteria, bacterium, or plant, as well as the effect on a substructure of the organism, such as a cell (biology), cell (cytotoxicity) or an organ such as the liver (hepatotoxicity). Sometimes the word is more or less synonymous with poison#Poisoning, poisoning in everyday usage. A central concept of toxicology is that the effects of a toxicant are Dose (biochemistry), dose-dependent; even water can lead to water intoxication when taken in too high a dose, whereas for even a very toxic substance such as snake venom there is a dose below which there is no detectable toxic effect. Toxicity is species-specific, making cross-species analysis problematic. Newer paradigms and metrics are evolving to bypass animal testing, while maintaining the concept of toxicity endpoints. Etymology In Ancient G ...
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Enema
An enema, also known as a clyster, is the rectal administration of a fluid by injection into the Large intestine, lower bowel via the anus.Cullingworth, ''A Manual of Nursing, Medical and Surgical'':155 The word ''enema'' can also refer to the liquid injected, as well as to a device for administering such an injection. In standard medicine, the most frequent uses of enemas are to relieve constipation and for bowel cleansing before a medical examination or procedure; also, they are employed as a lower gastrointestinal series (also called a barium enema), to treat Travelers' diarrhea, traveler's diarrhea, as a vehicle for the administration of food, water or medicine, as a stimulant to the general system, as a local application and, more rarely, as a means of reducing body temperature, as treatment for encopresis, and as a form of Management of dehydration, rehydration therapy (proctoclysis) in patients for whom intravenous therapy is not applicable. Medical usage The princip ...
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5-MeO-DMT
5-MeO-DMT (5-methoxy-''N'',''N''-dimethyltryptamine), also known as ''O''-methylbufotenin or mebufotenin (), is a naturally occurring psychedelic of the tryptamine family. It is found in a wide variety of plant species, and is also secreted by the glands of at least one toad species, the Colorado River toad. It may occur naturally in humans as well. Like its close relatives dimethyltryptamine (DMT) and bufotenin (5-HO-DMT), it has been used as an entheogen in South America. Slang terms include ''five-methoxy'', ''the power'', ''bufo'', and ''toad venom''. The drug has been described as the most powerful psychedelic and, by journalist Michael Pollan, as the "Mount Everest of psychedelics". Adverse effects of 5-MeO-DMT include sickness, vomiting, headache, chest pressure, fatigue, anxiety, fear, terror, confusion, paranoia, crying, loss of awareness and motor control, and reactivations. The drug acts as a non-selective serotonin receptor agonist, including of the sero ...
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Dimethyltryptamine
Dimethyltryptamine (DMT), also known as ''N'',''N''-dimethyltryptamine (''N'',''N''-DMT), is a Psychedelic drug, serotonergic hallucinogen and Investigational New Drug, investigational drug of the substituted tryptamine, tryptamine family that natural product, occurs naturally in many plants and animals, including humans. DMT is used as a psychedelic drug and prepared by various cultures for ritual purposes as an entheogen. DMT has a rapid onset of action, onset, intense effects, and a relatively short duration of action. For those reasons, DMT was known as the "businessman's trip" during the 1960s in the United States, as a user could access the full depth of a psychedelic experience in considerably less time than with other substances such as Lysergic acid diethylamide, LSD or psilocybin mushrooms. DMT can be inhaled or injected and its effects depend on the dose, as well as the mode of administration. When inhaled or injected, the effects last about five to fifteen minutes ...
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Bufotenin
Bufotenin, also known as dimethylserotonin or as 5-hydroxy-''N'',''N''-dimethyltryptamine (5-HO-DMT), is a serotonergic psychedelic of the tryptamine family. It is a derivative of the psychedelic dimethyltryptamine (DMT) and of the neurotransmitter serotonin (5-hydroxytryptamine; 5-HT). The compound is an alkaloid found in some species of mushrooms, plants, and toads. It is also found naturally in the human body in small amounts. Bufotenin, for instance derived from the trees ''Anadenanthera colubrina'' and ''Anadenanthera peregrina'', has a long history of entheogenic use as a snuff in South America. The name bufotenin originates from the toad genus '' Bufo'', which includes several species of psychoactive toads, most notably '' Incilius alvarius'' (formerly ''Bufo alvarius''), that secrete bufotoxins from their parotoid glands. However, ''Bufo'' and related species like ''Incilius alvarius'' contain only trace amounts of bufotenin, with their major active component instead ...
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Serotonergic Psychedelic
Psychedelics are a subclass of hallucinogenic drugs whose primary effect is to trigger non-ordinary mental states (known as psychedelic experiences or "trips") and a perceived "expansion of consciousness". Also referred to as classic hallucinogens or serotonergic hallucinogens, the term ''psychedelic'' is sometimes used more broadly to include various other types of hallucinogens as well, such as those which are atypical or adjacent to psychedelia like salvia and MDMA, respectively. Classic psychedelics generally cause specific psychological, visual, and auditory changes, and oftentimes a substantially altered state of consciousness. They have had the largest influence on science and culture, and include mescaline, LSD, psilocybin, and DMT. There are a large number of both naturally occurring and synthetic serotonergic psychedelics. Most psychedelic drugs fall into one of the three families of chemical compounds: tryptamines, phenethylamines, or lysergamides. They pro ...
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Cébil
''Anadenanthera colubrina'' (also known as vilca, huilco, huilca, wilco, willka, curupay, curupau, cebil, or angico) is a South American tree closely related to yopo, or ''Anadenanthera peregrina''. It grows to tall and the trunk is very thorny. The leaves are mimosa-like, up to in length and they fold up at night. In Argentina, ''A. colubrina'' produces flowers from September to December and bean pods from September to July. In Brazil ''A. colubrina'' has been given "high priority" conservation status. Nomenclature ''Anadenanthera colubrina'' is known by many names throughout South America. In Peru it is known as ''willka'' (also spelled ''wilca,'' ''vilca'' and ''huilca'') which in the Quechua languages means "sacred". Geography ''A. colubrina'' is found in Argentina, Bolivia, Brazil, Ecuador, Paraguay, Peru, Cuba, and Mauritius. Natural growing conditions ''A. colubrina'' grows at altitudes of about with roughly per year of precipitation and a mean temperature ...
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