HLA-B54

	HLA-B54 HLA-B54 (B54) is an HLA- B serotype. B54 is a split antigen from the B22 broad antigen Broad(s) or The Broad(s) may refer to: People * A slang term for a woman. * Broad (surname), a surname Places * Broad Peak, on the border between Pakistan and China, the 12th highest mountain on Earth * The Broads, a network of mostly nav ..., sister serotypes are B55 and B56. The serotype identifies the more common HLA-B55 gene products. Serotype Allele distribution See also HLA-serotype tutorial References {{DEFAULTSORT:Hla-B54 5 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	HLA-B22 HLA-B22 (B22) is an Human leukocyte antigen, HLA - HLA-B, B serotype. B22 is a broad antigen serotype that recognizes the HLA-B54, B54, HLA-B55, B55, and HLA-B56, B56 split antigen serotypes. References HLA-B alleles, 2 {{genetics-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	HLA-B HLA-B (major histocompatibility complex, class I, B) is a human gene that provides instructions for making a protein that plays a critical role in the immune system. HLA-B is part of a family of genes called the human leukocyte antigen (HLA) complex. The HLA complex helps the immune system distinguish the body's own proteins from proteins made by foreign invaders such as viruses and bacteria. HLA is the human version of the major histocompatibility complex (MHC), a gene family that occurs in many species. Genes in this complex are separated into three basic groups: class I, class II, and class III. In humans, the HLA-B gene and two related genes, HLA-A and HLA-C, are the major genes in MHC class I. MHC class I genes provide instructions for making proteins that are present on the surface of almost all cells. On the cell surface, these proteins are bound to protein fragments (peptides) that have been exported from within the cell. MHC class I proteins display these peptides to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	HLA-B55 HLA-B55 (B55) is an Human leukocyte antigen, HLA-HLA-B, B serotype. B55 is a split antigen from the HLA-B22, B22 broad antigen, sister serotypes are HLA-B54, B54 and HLA-B56, B56. The serotype identifies the more common HLA-B55 gene products. (For terminology help see: HLA-A#Historical Guide to Understanding Nomenclature, HLA-serotype tutorial) Serotype B55:03 is one of the four B alleles that reacts with neither Bw4 nor Bw6. The others are HLA-B18, B18:06, HLA-B46, B46:01, and HLA-B73, B73:01. Allele distribution References {{DEFAULTSORT:Hla-B55 HLA-B alleles, 5 ... [...More Info...] [...Related Items...] OR:* [Wikipedia] [Google] [Baidu]
	HLA-B56 HLA-B56 (B56) is an HLA- B serotype. B56 is a split antigen from the B22 broad antigen Broad(s) or The Broad(s) may refer to: People * A slang term for a woman. * Broad (surname), a surname Places * Broad Peak, on the border between Pakistan and China, the 12th highest mountain on Earth * The Broads, a network of mostly nav ..., sister serotypes are B54 and B55. The serotype identifies the more common HLA-B56 gene products. (For terminology help see: HLA-serotype tutorial) Serotype Allele distribution References {{DEFAULTSORT:Hla-B56 5 ... [...More Info...] [...Related Items...] OR:* [Wikipedia] [Google] [Baidu]
	Human Genome Organisation The Human Genome Organisation (HUGO) is a non-profit organization founded in 1988. HUGO represents an international coordinating scientific body in response to initiatives such as the Human Genome Project. HUGO has four active committees, including the HUGO Gene Nomenclature Committee (HGNC), and the HUGO Committee on Ethics, Law and Society (CELS). History HUGO was established at the first meeting on genome mapping and sequencing at Cold Spring Harbor in 1988. The idea of starting the organization stemmed from South African biologist Sydney Brenner, who is best known for his significant contributions to work on the genetic code and other areas of molecular biology, as well as winning the 2002 Nobel Prize in Physiology or Medicine. A Founding Council was elected at the meeting with a total of 42 scientists from 17 different countries, with Victor A. McKusick serving as founding President. In 2016, HUGO was located at the EWHA Womans University in Seoul, South Korea. In 2020, the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	European Bioinformatics Institute The European Bioinformatics Institute (EMBL-EBI) is an intergovernmental organization (IGO) which, as part of the European Molecular Biology Laboratory (EMBL) family, focuses on research and services in bioinformatics. It is located on the Wellcome Genome Campus in Hinxton near Cambridge, and employs over 600 full-time equivalent (FTE) staff. Further, the EMBL-EBI hosts training programs that teach scientists the fundamentals of the work with biological data and promote the plethora of bioinformatic tools available for their research, both EMBL-EBI-based and not so. Bioinformatic services One of the roles of the EMBL-EBI is to index and maintain biological data in a set of databases, including Ensembl (housing whole genome sequence data), UniProt (protein sequence and annotation database) and Protein Data Bank (protein and nucleic acid tertiary structure database). A variety of online services and tools is provided, such as Basic Local Alignment Search Tool (BLAST) or Clust ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
picture info	Locus (genetics) In genetics, a locus (: loci) is a specific, fixed position on a chromosome where a particular gene or genetic marker is located. Each chromosome carries many genes, with each gene occupying a different position or locus; in humans, the total number of Human genome#Coding sequences (protein-coding genes), protein-coding genes in a complete haploid set of 23 chromosomes is estimated at 19,000–20,000. Genes may possess multiple variants known as alleles, and an allele may also be said to reside at a particular locus. Diploid and polyploid cells whose chromosomes have the same allele at a given locus are called homozygote, homozygous with respect to that locus, while those that have different alleles at a given locus are called heterozygote, heterozygous. The ordered list of loci known for a particular genome is called a gene map. Gene mapping is the process of determining the specific locus or loci responsible for producing a particular phenotype or biological trait. Association ma ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Chromosome 6 (human) Chromosome 6 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 6 spans nearly 171 million base pairs (the building material of DNA) and represents between 5.5 and 6% of the total DNA in cells. It contains the major histocompatibility complex, which contains over 100 genes related to the immune response, and plays a vital role in organ transplantation. The evolution of human centromere 6 The centromere of chromosome 6 illustrates an interesting example of centromere evolution. It was known that in a Catarrhini ancestor the chromosome 6 centromere was situated near position 26 Mb of the modern human chromosome. In ''Macaca mulatta'', this old centromere went defunct and repositioned to a different chromosomal location. In the case of humans, the old centromere went defunct and a more recent form emerged near the modern position of human cen6 (size of 60 Mb). Such cases are known as Evolutionary New Centromeres (ENC). ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
picture info	Human Leukocyte Antigen The human leukocyte antigen (HLA) system is a complex of genes on chromosome 6 in humans that encode cell-surface proteins responsible for regulation of the immune system. The HLA system is also known as the human version of the major histocompatibility complex (MHC) found in many animals. Mutations in HLA genes may be linked to autoimmune diseases such as type I diabetes, and celiac disease. The HLA gene complex resides on a 3 Mbp stretch within chromosome 6, p-arm at 21.3. HLA genes are highly polymorphic, which means that they have many different alleles, allowing them to fine-tune the adaptive immune system. The proteins encoded by certain genes are also known as '' antigens'', as a result of their historic discovery as factors in organ transplants. HLAs corresponding to MHC class I ( A, B, and C), all of which are the HLA Class1 group, present peptides from inside the cell. For example, if the cell is infected by a virus, the HLA system brings fragments of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
picture info	Serotype A serotype or serovar is a distinct variation within a species of bacteria or virus or among immune cells of different individuals. These microorganisms, viruses, or Cell (biology), cells are classified together based on their shared reactivity between their surface antigens and a particular antiserum, allowing the classification of organisms to a Infraspecific name, level below the species. A group of serovars with common antigens is called a serogroup or sometimes ''serocomplex''. Serotyping often plays an essential role in determining species and subspecies. The ''Salmonella'' genus of bacteria, for example, has been determined to have over 2600 serotypes. ''Vibrio cholerae'', the species of bacteria that causes cholera, has over 200 serotypes, based on cell antigens. Only two of them have been observed to produce the potent enterotoxin that results in cholera: O1 and O139. Serotypes were discovered in hemolytic streptococci by the American microbiologist Rebecca Lancefield i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Split Antigen Split(s) or The Split may refer to: Places * Split, Croatia, the largest coastal city in Croatia * Split Island, Canada, an island in the Hudson Bay * Split Island, Falkland Islands * Split Island, Fiji, better known as Hạfliua Arts, entertainment, and media Films * ''Split'' (1989 film), a science fiction film * ''Split'' (2016 American film), a psychological horror thriller film * ''Split'' (2016 Canadian film), also known as ''Écartée'', a Canadian drama film directed by Lawrence Côté-Collins * ''Split'' (2016 South Korean film), a sports drama film * '' Split: A Divided America'', a 2008 documentary on American politics * ''The Split'' (film), a 1968 heist film * ''The Split'', or ''The Manster'', a U.S.-Japanese horror film Games * Split (poker), the division of winnings in the card game * Split (blackjack), a possible player decision in the card game Music Albums * ''Split'' (The Groundhogs album), 1971 * ''Split'' (Lush album), 1994 * ''Split'' (Patricia ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Broad Antigen Broad(s) or The Broad(s) may refer to: People * A slang term for a woman. * Broad (surname), a surname Places * Broad Peak, on the border between Pakistan and China, the 12th highest mountain on Earth * The Broads, a network of mostly navigable rivers and lakes in the English counties of Norfolk and Suffolk, United Kingdom *The Broads include several areas of navigable water known as Broads; the largest is Hickling Broad (see :Norfolk Broads) The Broads (New Hampshire), a wide portion of Lake Winnipesaukee in Belknap County, New Hampshire, United States * Broad Bay (other) * Broad Canal, East Cambridge, Massachusetts, United States * Broad Channel, a neighborhood in Queens, United States * Broad Crag, a fell in the English Lake District, United Kingdom * Broad Creek (other) * Broad River (other) * Broad Run (other) * Broad Sound (other) * Broad Valley, Graham Land, Antarctica * Broad Water, a salt water lagoon near Tyw ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]