|
HIstome
HIstome is a database that provides information about human histone proteins, their sites of modifications, variants and modifying enzymes, and diseases linked to histone modifications. Update HISTome2 is an updated version of the HIstome database released in 2020. See also * Histone In biology, histones are highly basic proteins abundant in lysine and arginine residues that are found in eukaryotic cell nuclei and in most Archaeal phyla. They act as spools around which DNA winds to create structural units called nucleosomes ... References External links * http://www.iiserpune.ac.in/~coee/histome/ Protein databases Epigenetics {{Biodatabase-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Database
In computing, a database is an organized collection of data or a type of data store based on the use of a database management system (DBMS), the software that interacts with end users, applications, and the database itself to capture and analyze the data. The DBMS additionally encompasses the core facilities provided to administer the database. The sum total of the database, the DBMS and the associated applications can be referred to as a database system. Often the term "database" is also used loosely to refer to any of the DBMS, the database system or an application associated with the database. Before digital storage and retrieval of data have become widespread, index cards were used for data storage in a wide range of applications and environments: in the home to record and store recipes, shopping lists, contact information and other organizational data; in business to record presentation notes, project research and notes, and contact information; in schools as flash c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Histone
In biology, histones are highly basic proteins abundant in lysine and arginine residues that are found in eukaryotic cell nuclei and in most Archaeal phyla. They act as spools around which DNA winds to create structural units called nucleosomes. Nucleosomes in turn are wrapped into 30- nanometer fibers that form tightly packed chromatin. Histones prevent DNA from becoming tangled and protect it from DNA damage. In addition, histones play important roles in gene regulation and DNA replication. Without histones, unwound DNA in chromosomes would be very long. For example, each human cell has about 1.8 meters of DNA if completely stretched out; however, when wound about histones, this length is reduced to about 9 micrometers (0.09 mm) of 30 nm diameter chromatin fibers. There are five families of histones, which are designated H1/H5 (linker histones), H2, H3, and H4 (core histones). The nucleosome core is formed of two H2A-H2B dimers and a H3-H4 tetramer. The tight wr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Indian Institute Of Science Education And Research, Pune
Indian Institute of Science Education and Research, Pune (IISER Pune) is an autonomous public university established in 2006. It is one of the seven Indian Institutes of Science Education and Research, and was one of the first IISERs to be established along with IISER Kolkata. It is located in the city of Pune, India. Campus The construction of the final campus was completed in 2012. The campus is of 98 acres. Academics Academic programmes IISER Pune offers integrated masters programmes (BS-MS), a Masters by Research (MS), an integrated doctoral programme (Int. PhD) and a doctoral programme (PhD). Admission to the BS-MS programme is exclusively through the IISER Aptitude Test (IAT) from 2024. JEE Advanced and KVPY are no longer valid channels for admission. Admission to the various PhD programmes is either with a master's degree in science or with a bachelor's degree, for the integrated PhD programme. Candidates are screened by interviews. In addition to that ca ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tata Memorial Centre
The Tata Memorial Center (TMC) is an autonomous grant-in-aid institution administered under the Department of Atomic Energy, Government of India. The TMC umbrella includes at least 10 cancer institutes across India, the largest and the central hub of which is the Tata Memorial Hospital (TMH) in Parel, Mumbai, is India's oldest and largest cancer institute. It has spearheaded the Evidence-based Medicine (EBM) movement in oncology in India, and prioritizes Multidisciplinary Team (MDT) management through disease-specific groups, to ensure quality patient care. There are many firsts to the TMC name. These include India's first linear accelerator for radiation therapy in 1978, bone marrow transplant in 1983, tissue bank in 1988, PET/CT in 2004, and the first proton therapy unit in a government setup (and second overall) in 2023. It has spearheaded the CAR-T cell trial which has led to the approval indigenous CAR-T cell therapy in India. Importantly, with a mission centered on compr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein Databases
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific 3D structure that determines its activity. A linear chain of amino acid residues is called a polypeptide. A protein contains at least one long polypeptide. Short polypeptides, containing less than 20–30 residues, are rarely considered to be proteins and are commonly called peptides. The individual amino acid residues are bonded together by peptide bonds and adjacent amino acid residues. The sequence of amino acid residues i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
