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Guido Fanconi
Guido Fanconi () (1 January 1892 – 10 October 1979) was a Swiss pediatrician. Biography Fanconi was born on 1 January 1892 in Poschiavo, a small village in the Canton of Grisons. Fanconi is regarded as one of the founders of modern pediatrics. He received his secondary school education in Zürich. In 1911, he began his medical training in Lausanne. In 1920, he entered the Kinderspital (Children's Hospital) of the University of Zurich, where, with the exception of one year, he remained for 45 years. Fanconi recognized the importance of biochemistry to clinical medicine. In 1929 he succeeded Emil Feer as professor of pediatrics and head of the Kinderspital. Under his direction, it became one of the most renowned children's hospitals in the world. There are several medical conditions named after Dr. Fanconi. In 1927 he described hereditary panmyelopathy with short stature and hyperpigmentation, better known as Fanconi anemia. In 1934 the first cases of cystic fibrosis of the panc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
People From Poschiavo
The term "the people" refers to the public or common mass of people of a polity. As such it is a concept of human rights law, international law as well as constitutional law, particularly used for claims of popular sovereignty. In contrast, a people is any plurality of persons considered as a whole. Used in politics and law, the term "a people" refers to the collective or community of an ethnic group or nation. Concepts Legal Chapter One, Article One of the Charter of the United Nations states that "peoples" have the right to self-determination. Though the mere status as peoples and the right to self-determination, as for example in the case of Indigenous peoples (''peoples'', as in all groups of indigenous people, not merely all indigenous persons as in ''indigenous people''), does not automatically provide for independent sovereignty and therefore secession. Indeed, judge Ivor Jennings identified the inherent problems in the right of "peoples" to self-determination, as i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1979 Deaths
Events January * January 1 ** United Nations Secretary-General Kurt Waldheim heralds the start of the ''International Year of the Child''. Many musicians donate to the ''Music for UNICEF Concert'' fund, among them ABBA, who write the song ''Chiquitita'' to commemorate the event. ** In 1979, the United States officially severed diplomatic ties with the Republic of China (Taiwan). This decision marked a significant shift in U.S. foreign policy, turning to view the People's Republic of China as the sole legitimate representative of China. ** The United States and the People's Republic of China establish full Sino-American relations, diplomatic relations. ** Following a deal agreed during 1978, France, French carmaker Peugeot completes a takeover of American manufacturer Chrysler's Chrysler Europe, European operations, which are based in United Kingdom, Britain's former Rootes Group factories, as well as the former Simca factories in France. * January 6 – Geylang Bahru family ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1892 Births
In Samoa, this was the only leap year spanned to 367 days as July 4 repeated. This means that the International Date Line was drawn from the east of the country to go west. Events January * January 1 – Ellis Island begins processing Immigration to the United States, immigrants to the United States. February * February 27 – Rudolf Diesel applies for a patent, on his compression ignition engine (the Diesel engine). * February 29 – St. Petersburg, Florida is incorporated as a town. March * March 1 – Theodoros Deligiannis ends his term as Prime Minister of Greece and Konstantinos Konstantopoulos takes office. * March 6–March 8, 8 – "Exclusive Agreement": Rulers of the Trucial States (Abu Dhabi, Dubai, Sharjah, Ajman, Ras al-Khaimah and Umm al-Quwain) sign an agreement, by which they become ''de facto'' British protectorates. * March 11 – The first basketball game is played in public, between students and faculty at the Springfield YMCA before 200 spectators. The ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nature Reviews Cancer
''Nature Reviews Cancer'' is a monthly review journal covering the field of oncology. It was established in 2001. The editor-in-chief is Anna Dart. Abstracting and indexing The journal is abstracted and indexed in: *PubMed *Science Citation Index Expanded *Scopus *MedlineSCIMAGOJRref> According to the ''Journal Citation Reports'', the journal has a 2021 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a type of journal ranking. Journals with higher impact factor values are considered more prestigious or important within their field. The Impact Factor of a journa ... of 69.800, ranking it 2nd out of 245 journals in the category "Oncology". References External links * Oncology journals Nature Research academic journals English-language journals Monthly journals Academic journals established in 2001 Review journals {{oncology-journal-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fanconi–Bickel Syndrome
Fanconi–Bickel syndrome is a form of glycogen storage disease named for Guido Fanconi and Horst Bickel, who first described it in 1949. It is associated with GLUT2 Glucose transporter 2 (GLUT2) also known as solute carrier family 2 (facilitated glucose transporter), member 2 (SLC2A2) is a transmembrane carrier protein that enables protein facilitated glucose movement across cell membranes. It is the princi ..., a glucose transport protein which, when functioning normally, allows glucose to exit several tissues, including the liver, nephrons, and enterocytes of the intestines, and enter the blood. The syndrome results in hepatomegaly secondary to glycogen accumulation, glucose and galactose intolerance, fasting hypoglycaemia, a characteristic proximal tubular nephropathy and severe short stature. References External links Inborn errors of carbohydrate metabolism Hepatology Muscular disorders {{endocrine-disease-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Helvetica Paediatrica Acta
Helvetica, also known by its original name Neue Haas Grotesk, is a widely-used sans-serif typeface developed in 1957 by Swiss Type design#Profession, typeface designer Max Miedinger and Eduard Hoffmann. Helvetica is a Sans-serif#Neo-grotesque, neo-grotesque design, one influenced by the famous 19th-century (1890s) typeface Akzidenz-Grotesk and other German and Swiss designs. Its use became a hallmark of the International Typographic Style that emerged from the work of Swiss designers in the 1950s and 1960s, becoming one of the most popular typefaces of the mid-20th century. Over the years, a wide range of variants have been released in different weights, widths, and sizes, as well as matching designs for a range of non-Latin alphabets. Notable features of Helvetica as originally designed include a high x-height, the termination of strokes on horizontal or vertical lines and an unusually tight spacing between letters, which combine to give it a dense, solid appearance. Develope ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fanconi Syndrome
Fanconi syndrome or Fanconi's syndrome (, ) is a syndrome of inadequate reabsorption in the proximal renal tubules of the kidney. The syndrome can be caused by various underlying congenital or acquired diseases, by toxicity (for example, from toxic heavy metals), or by adverse drug reactions. It results in various small molecules of metabolism being passed into the urine instead of being reabsorbed from the tubular fluid (for example, glucose, amino acids, uric acid, phosphate, and bicarbonate). Fanconi syndrome affects the proximal tubules, namely, the proximal convoluted tubule (PCT), which is the first part of the tubule to process fluid after it is filtered through the glomerulus, and the proximal straight tubule (pars recta), which leads to the descending limb of loop of Henle. Different forms of Fanconi syndrome can affect different functions of the proximal tubule, and result in different complications. The loss of bicarbonate results in type 2 or proximal renal ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Renal Physiology
Renal physiology (Latin language, Latin ''renes'', "kidneys") is the study of the physiology of the kidney. This encompasses all functions of the kidney, including maintenance of acid-base balance; regulation of fluid balance; regulation of sodium, potassium, and other electrolytes; clearance (medicine), clearance of toxins; absorption of glucose, amino acids, and other small molecules; regulation of blood pressure; production of various hormones, such as erythropoietin; and activation of vitamin D. Much of renal physiology is studied at the level of the nephron, the smallest functional unit of the kidney. Each nephron begins with a #Filtration, filtration component that filters the blood entering the kidney. This filtrate then flows along the length of the nephron, which is a tubular structure lined by a single layer of specialized cell (biology), cells and surrounded by capillary, capillaries. The major functions of these lining cells are the reabsorption of water and small mol ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Polio
Poliomyelitis ( ), commonly shortened to polio, is an infectious disease caused by the poliovirus. Approximately 75% of cases are asymptomatic; mild symptoms which can occur include sore throat and fever; in a proportion of cases more severe symptoms develop such as headache, neck stiffness, and paresthesia. These symptoms usually pass within one or two weeks. A less common symptom is permanent Flaccid paralysis, paralysis, and possible death in extreme cases.. Years after recovery, post-polio syndrome may occur, with a slow development of muscle weakness similar to what the person had during the initial infection. Polio occurs naturally only in humans. It is highly infectious, and is spread from person to person either through fecal–oral route, fecal–oral transmission (e.g. poor hygiene, or by ingestion of food or water contaminated by human feces), or via the oral–oral route. Those who are infected may spread the disease for up to six weeks even if no symptoms are pre ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
