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Gordon A. Alles
Gordon A. Alles (November 26, 1901 – January 21, 1963), was an American chemist and pharmacologist who did extensive research on the isolation and properties of insulin for the treatment of diabetics. He is also credited with discovering and publishing the physiological effects of amphetamine and methylenedioxyamphetamine (MDA).''On Speed: The Many Lives of Amphetamine''. Nicolas Rasmussen (2008). He is the first person to have prepared amphetamine sulfate, although not the amphetamine molecule. Alles first reported the physiological properties of amphetamine as a synthetic analog of ephedrine, and therefore received credit for this discovery.Staff, (1963''Gordon A. Alles.'' The Month at Caltech.Engineering and Science, 26 (5). pp. 18-19. ISSN 0013-7812] He enjoyed large royalties from Smith, Kline & French (SKF) because he sold his patent rights for amphetamine to the company and it enjoyed large sales. Several popular products sold by SKF contained amphetamine, including Benze ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
United States
The United States of America (USA), also known as the United States (U.S.) or America, is a country primarily located in North America. It is a federal republic of 50 U.S. state, states and a federal capital district, Washington, D.C. The 48 contiguous states border Canada to the north and Mexico to the south, with the semi-exclave of Alaska in the northwest and the archipelago of Hawaii in the Pacific Ocean. The United States asserts sovereignty over five Territories of the United States, major island territories and United States Minor Outlying Islands, various uninhabited islands in Oceania and the Caribbean. It is a megadiverse country, with the world's List of countries and dependencies by area, third-largest land area and List of countries and dependencies by population, third-largest population, exceeding 340 million. Its three Metropolitan statistical areas by population, largest metropolitan areas are New York metropolitan area, New York, Greater Los Angeles, Los Angel ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bachelor Of Science
A Bachelor of Science (BS, BSc, B.S., B.Sc., SB, or ScB; from the Latin ') is a bachelor's degree that is awarded for programs that generally last three to five years. The first university to admit a student to the degree of Bachelor of Science was the University of London in 1860. In the United States, the Lawrence Scientific School first conferred the degree in 1851, followed by the University of Michigan in 1855. Nathaniel Shaler, who was Harvard's Dean of Sciences, wrote in a private letter that "the degree of Bachelor of Science came to be introduced into our system through the influence of Louis Agassiz, who had much to do in shaping the plans of this School." Whether Bachelor of Science or Bachelor of Arts degrees are awarded in particular subjects varies between universities. For example, an economics student may graduate as a Bachelor of Arts in one university but as a Bachelor of Science in another, and occasionally, both options are offered. Some universities follo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1901 Births
December 13 of this year is the beginning of signed 32-bit computing, 32-bit Unix time, and is scheduled to end in Year 2038 problem, January 19, 2038. Summary Political and military 1901 started with the Federation of Australia, unification of multiple Crown colony, British colonies in Australia on January 1 to form the Australia, Commonwealth of Australia after a 1898–1900 Australian constitutional referendums, referendum in 1900, Subsequently, the 1901 Australian federal election, 1901 Australian election would see the first Prime Minister of Australia, Australian prime minister, Edmund Barton. On the same day, Nigeria became a Colonial Nigeria, British protectorate. Following this, the Victorian era, Victorian Era would come to a end after Queen Victoria died on January 22 after a reign of 63 years and 216 days, which was List of monarchs in Britain by length of reign, longer than those of any of her predecessors, Her son, Edward VII, succeeded her to the throne. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kava
Kava or kava kava (''Piper methysticum'': Latin 'pepper' and Latinized Ancient Greek, Greek 'intoxicating') is a plant in the Piperaceae, pepper family, native to the Pacific Islands. The name ''kava'' is from Tongan language, Tongan and Marquesan language, Marquesan, meaning 'bitter'. Kava can refer to either the plant or a Psychoactive drug, psychoactive beverage made from its root. The beverage is a traditional ceremonial and recreational drink from Polynesia, Micronesia, and Melanesia. Nakamals and kava bar (establishment), bars exist in many countries. Traditional kava is made by grinding fresh or dried kava root, mixing it with water or coconut milk, and straining it into a communal bowl. Outside the South Pacific, kava is typically prepared by soaking dried root powder in water and straining it. It is Social lubricant, consumed socially for its sedative, hypnotic, muscle relaxant, anxiolytic, and euphoric effects, comparable to those produced by alcohol (drug), alcohol. K ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alkaloid
Alkaloids are a broad class of natural product, naturally occurring organic compounds that contain at least one nitrogen atom. Some synthetic compounds of similar structure may also be termed alkaloids. Alkaloids are produced by a large variety of organisms including bacteria, fungus, fungi, Medicinal plant, plants, and animals. They can be purified from crude extracts of these organisms by acid-base extraction, or solvent extractions followed by silica-gel column chromatography. Alkaloids have a wide range of pharmacology, pharmacological activities including antimalarial medication, antimalarial (e.g. quinine), asthma, antiasthma (e.g. ephedrine), chemotherapy, anticancer (e.g. omacetaxine mepesuccinate, homoharringtonine), cholinomimetic (e.g. galantamine), vasodilation, vasodilatory (e.g. vincamine), Antiarrhythmic agent, antiarrhythmic (e.g. quinidine), analgesic (e.g. morphine), antibacterial (e.g. chelerythrine), and anti-diabetic, antihyperglycemic activities (e.g. berb ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tranquilizer
A sedative or tranquilliser is a substance that induces sedation by reducing irritability or excitement. They are central nervous system (CNS) depressants and interact with brain activity, causing its deceleration. Various kinds of sedatives can be distinguished, but the majority of them affect the neurotransmitter gamma-aminobutyric acid (GABA). Most sedatives produce relaxing effects by increasing GABA activity. This group is related to hypnotics. The term ''sedative'' describes drugs that serve to calm or relieve anxiety, whereas the term ''hypnotic'' describes drugs whose main purpose is to initiate, sustain, or lengthen sleep. Because these two functions frequently overlap, and because drugs in this class generally produce dose-dependent effects (ranging from anxiolysis to loss of consciousness), they are often referred to collectively as ''sedative–hypnotic'' drugs. Terminology There is some overlap between the terms "sedative" and "hypnotic". Advances in pharmacolo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tahiti
Tahiti (; Tahitian language, Tahitian , ; ) is the largest island of the Windward Islands (Society Islands), Windward group of the Society Islands in French Polynesia, an overseas collectivity of France. It is located in the central part of the Pacific Ocean and the nearest major landmass is the North Island of New Zealand. The island was formed from Volcano, volcanic activity in two overlapping parts, ''Tahiti Nui'' (bigger, northwestern part) and ''Tahiti Iti'' (smaller, southeastern part); it is high and mountainous with surrounding coral reefs. Its population was 189,517 in 2017, making it by far the most populous island in French Polynesia and accounting for 68.7% of its total population; the 2022 Census recorded a population of 191,779. Tahiti is the economic, cultural, and political centre of French Polynesia. The capital of French Polynesia, Papeete, Papeete, is located on the northwest coast of Tahiti. The only international airport in the region, Faaʻa International ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stimulant
Stimulants (also known as central nervous system stimulants, or psychostimulants, or colloquially as uppers) are a class of drugs that increase alertness. They are used for various purposes, such as enhancing attention, motivation, cognition, Mood disorder, mood, and physical activity, physical performance. Some stimulants occur naturally, while others are exclusively synthetic. Common stimulants include caffeine, nicotine, amphetamines, cocaine, methylphenidate, and modafinil. Stimulants may be subject to varying forms of regulation, or outright prohibition, depending on jurisdiction. Stimulants increase activity in the sympathetic nervous system, either directly or indirectly. Prototypical stimulants increase synaptic concentrations of neurotransmitter, excitatory neurotransmitters, particularly norepinephrine and dopamine (e.g., methylphenidate). Other stimulants work by binding to the Receptor (biochemistry), receptors of excitatory neurotransmitters (e.g., nicotine) or by ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dextroamphetamine
Dextroamphetamine (international nonproprietary name, INN: dexamfetamine) is a potent central nervous system (CNS) stimulant and enantiomer of amphetamine that is used in the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy. It is also used illicitly to enhance Nootropic, cognitive and athletic Performance-enhancing substance, performance, and recreationally as an aphrodisiac and euphoriant. Dextroamphetamine is generally regarded as the prototype drug, prototypical stimulant. The amphetamine molecule exists as two enantiomers, levoamphetamine and dextroamphetamine. Dextroamphetamine is the Levorotation and dextrorotation, dextrorotatory, or 'right-handed', enantiomer and exhibits more pronounced effects on the central nervous system than levoamphetamine. Pharmaceutical dextroamphetamine sulfate is available as both a brand name and generic drug in a variety of dosage forms. Dextroamphetamine is sometimes prescribed as the inactive prodrug lisdexamfet ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Benzedrine
Amphetamine (contracted from alpha- methylphenethylamine) is a central nervous system (CNS) stimulant that is used in the treatment of attention deficit hyperactivity disorder (ADHD), narcolepsy, and obesity; it is also used to treat binge eating disorder in the form of its inactive prodrug lisdexamfetamine. Amphetamine was discovered as a chemical in 1887 by Lazăr Edeleanu, and then as a drug in the late 1920s. It exists as two enantiomers: levoamphetamine and dextroamphetamine. ''Amphetamine'' properly refers to a specific chemical, the racemic free base, which is equal parts of the two enantiomers in their pure amine forms. The term is frequently used informally to refer to any combination of the enantiomers, or to either of them alone. Historically, it has been used to treat nasal congestion and depression. Amphetamine is also used as an athletic performance enhancer and cognitive enhancer, and recreationally as an aphrodisiac and euphoriant. It is a prescription dru ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pasadena
Pasadena ( ) is a city in Los Angeles County, California, United States, northeast of downtown Los Angeles. It is the most populous city and the primary cultural center of the San Gabriel Valley. Old Pasadena is the city's original commercial district. Its population was 138,699 at the 2020 census, making it the 45th-largest city in California and the ninth-largest in Los Angeles County. Pasadena was incorporated on June 19, 1886, 36 years after the city of Los Angeles but still one of the first in what is now Los Angeles County. Pasadena is home to many scientific, educational, and cultural institutions, including the California Institute of Technology, Pasadena City College, Kaiser Permanente Bernard J. Tyson School of Medicine, Fuller Theological Seminary, Theosophical Society, Parsons Corporation, Art Center College of Design, the Planetary Society, Pasadena Playhouse, the Ambassador Auditorium, the Norton Simon Museum, and the USC Pacific Asia Museum. Pasadena hos ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
UCLA
The University of California, Los Angeles (UCLA) is a public land-grant research university in Los Angeles, California, United States. Its academic roots were established in 1881 as a normal school then known as the southern branch of the California State Normal School which later evolved into San José State University. The branch was transferred to the University of California to become the Southern Branch of the University of California in 1919, making it the second-oldest of the ten-campus University of California system after the University of California, Berkeley. UCLA offers 337 undergraduate and graduate degree programs in a range of disciplines, enrolling about 31,600 undergraduate and 14,300 graduate and professional students annually. It received 174,914 undergraduate applications for Fall 2022, including transfers, the most of any university in the United States. The university is organized into the College of Letters and Science and twelve professional schoo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
