Giancarlo Pepeu
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Giancarlo Pepeu
Giancarlo Pepeu (29 March 1930 – 20 November 2021) was an Italian Emeritus Professor of Pharmacology at the University of Florence and an Honorary Fellow of the British Pharmacological Society. He was from Milan and graduated with a Laurea degree in Medicine from the University of Florence to pursue an academic career. Biography Giancarlo Pepeu was born on 29 March 1930 in Milan, Italy. He was a member of the Pepeu family, whose earliest known member was Stefano Pepeu, a merchant in Trieste, born about 1750, presumably to immigrant parents. In the Pepeu family, it has been passed down that the surname Pepeu is of Istro-Romanian origin. The termination -u, common in surnames of the related Romanians, could be proof of distant Istro-Romanian ancestry of the Pepeu family. Giancarlo's family is the only one known to carry the surname Pepeu in Trieste and in the rest of Italy. Upon completing his studies in 1954, Giancarlo Pepeu began research at the Florence's Institute of P ...
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Trieste
Trieste ( , ; ) is a city and seaport in northeastern Italy. It is the capital and largest city of the Regions of Italy#Autonomous regions with special statute, autonomous region of Friuli-Venezia Giulia, as well as of the Province of Trieste, regional decentralization entity of Trieste. Trieste is located at the head of the Gulf of Trieste, on a narrow strip of Italian territory lying between the Adriatic Sea and Slovenia; Slovenia lies close, at approximately east and southeast of the city, while Croatia is about to the south of the city. The city has a long coastline and is surrounded by grassland, forest, and karstic areas. As of 2025, it has a population of 198,668. Trieste belonged, as Triest, to the Habsburg monarchy from 1382 until 1918. In the 19th century, the monarchy was one of the Great Powers of Europe and Trieste was its most important seaport. As a prosperous trading hub in the Mediterranean region, Trieste grew to become the fourth largest city of the Aust ...
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Istro-Romanians
The Istro-Romanians ( or ) are a Romance languages, Romance ethnic group native to or associated with the Istria, Istrian Peninsula. Historically, they inhabited vast parts of it, as well as the western side of the island of Krk until 1875. However, due to several factors such as the industrialization and modernization of Istria during the socialist regime of Socialist Federal Republic of Yugoslavia, Yugoslavia, many Istro-Romanians emigrated to other places, be they Croatian cities such as Pula and Rijeka or places such as New York City, Trieste and Western Australia. The Istro-Romanians dwindled severely in number, being reduced to eight Human settlement, settlements on the Croatian side of Istria in which they do not represent the Ethnic majority, majority. It is known that the Istro-Romanians are actually not indigenous to Istria, since the differences between the Istro-Romanian language and the now Language death, extinct geographically close Dalmatian language, Dalmatian ar ...
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Clinical Pharmacology
Clinical pharmacology is "that discipline that teaches, does research, frames policy, gives information and advice about the actions and proper uses of medicines in humans and implements that knowledge in clinical practice". Clinical pharmacology is inherently a translational discipline underpinned by the basic science of pharmacology, engaged in the experimental and observational study of the disposition and effects of drugs in humans, and committed to the translation of science into evidence-based therapeutics. It has a broad scope, from the discovery of new target molecules to the effects of drug usage in whole populations. The main aim of clinical pharmacology is to generate data for optimum use of drugs and the practice of 'evidence-based medicine'. Clinical pharmacologists have medical and scientific training that enables them to evaluate evidence and produce new data through well-designed studies. Clinical pharmacologists must have access to enough patients for clinical c ...
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Preclinical
In drug development, preclinical development (also termed preclinical studies or nonclinical studies) is a stage of research that begins before clinical trials (testing in humans) and during which important feasibility, iterative testing and drug safety data are collected, typically in laboratory animals. The main goals of preclinical studies are to determine a starting, safe dose for first-in-human study and assess potential toxicity of the product, which typically include new medical devices, prescription drugs, and diagnostics. Companies use stylized statistics to illustrate the risks in preclinical research, such as that on average, only one in every 5,000 compounds that enters drug discovery to the stage of preclinical development becomes an approved drug. Types Each class of product may undergo different types of preclinical research. For instance, drugs may undergo pharmacodynamics (what the drug does to the body) (PD), pharmacokinetics (what the body does to th ...
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International Relations
International relations (IR, and also referred to as international studies, international politics, or international affairs) is an academic discipline. In a broader sense, the study of IR, in addition to multilateral relations, concerns all activities among states—such as war, diplomacy, trade, and foreign policy—as well as relations with and among other international actors, such as intergovernmental organizations (IGOs), international nongovernmental organizations (INGOs), international legal bodies, and multinational corporations (MNCs). International relations is generally classified as a major multidiscipline of political science, along with comparative politics, political methodology, political theory, and public administration. It often draws heavily from other fields, including anthropology, economics, geography, history, law, philosophy, and sociology. There are several schools of thought within IR, of which the most prominent are realism, l ...
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Scientific Research
The scientific method is an empirical method for acquiring knowledge that has been referred to while doing science since at least the 17th century. Historically, it was developed through the centuries from the ancient and medieval world. The scientific method involves careful observation coupled with rigorous skepticism, because cognitive assumptions can distort the interpretation of the observation. Scientific inquiry includes creating a testable hypothesis through inductive reasoning, testing it through experiments and statistical analysis, and adjusting or discarding the hypothesis based on the results. Although procedures vary across fields, the underlying process is often similar. In more detail: the scientific method involves making conjectures (hypothetical explanations), predicting the logical consequences of hypothesis, then carrying out experiments or empirical observations based on those predictions. with added notes. Reprinted with previously unpublished part, ...
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Dean (education)
Dean is a title employed in academic administrations such as colleges or universities for a person with significant authority over a specific academic unit, over a specific area of concern, or both. In the United States and Canada, deans are usually university professors who serve as the heads of a university's constituent colleges and schools. Deans are common in private preparatory schools, and occasionally found in middle schools and high schools as well. Origin A "dean" (Latin: '' decanus'') was originally the head of a group of ten soldiers or monks. Eventually an ecclesiastical dean became the head of a group of canons or other religious groups. When the universities grew out of the cathedral schools and monastic schools, the title of dean was used for officials with various administrative duties. Use Bulgaria and Romania In Bulgarian and Romanian universities, a dean is the head of a faculty, which may include several academic departments. Every faculty unit of u ...
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Pharmacology
Pharmacology is the science of drugs and medications, including a substance's origin, composition, pharmacokinetics, pharmacodynamics, therapeutic use, and toxicology. More specifically, it is the study of the interactions that occur between a living organism and chemicals that affect normal or abnormal biochemical function. If substances have medicinal properties, they are considered pharmaceuticals. The field encompasses drug composition and properties, functions, sources, synthesis and drug design, molecular and cellular mechanisms, organ/systems mechanisms, signal transduction/cellular communication, molecular diagnostics, interactions, chemical biology, therapy, and medical applications and antipathogenic capabilities. The two main areas of pharmacology are pharmacodynamics and pharmacokinetics. Pharmacodynamics studies the effects of a drug on biological systems, and pharmacokinetics studies the effects of biological systems on a drug. In broad terms, pharmacod ...
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Full Professor
Professor (commonly abbreviated as Prof.) is an academic rank at universities and other post-secondary education and research institutions in most countries. Literally, ''professor'' derives from Latin as a 'person who professes'. Professors are usually experts in their field and teachers of the highest rank. In most systems of academic ranks, "professor" as an unqualified title refers only to the most senior academic position, sometimes informally known as "full professor". In some countries and institutions, the word ''professor'' is also used in titles of lower ranks such as associate professor and assistant professor; this is particularly the case in the United States, where the unqualified word is also used colloquially to refer to associate and assistant professors as well, and often to instructors or lecturers. Professors often conduct original research and commonly teach undergraduate, postgraduate, or professional courses in their fields of expertise. In universiti ...
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Cagliari
Cagliari (, , ; ; ; Latin: ''Caralis'') is an Comune, Italian municipality and the capital and largest city of the island of Sardinia, an Regions of Italy#Autonomous regions with special statute, autonomous region of Italy. It has about 146,627 inhabitants, while its Metropolitan City of Cagliari, metropolitan city, 16 other nearby municipalities, has about 417,079 inhabitants. According to Eurostat, the population of the Functional urban area, functional urban area, the commuting zone of Cagliari, rises to 476,975. Cagliari is the 26th largest city in Italy and the largest city on the island of Sardinia. An ancient city with a long history, Cagliari has seen the rule of several civilisations. Under the buildings of the modern city there is a continuous stratification attesting to human settlement over the course of some five thousand years, from the Neolithic to today. Historical sites include the prehistoric Domus de Janas, partly damaged by cave activity, a large Ancient Car ...
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Pisa
Pisa ( ; ) is a city and ''comune'' (municipality) in Tuscany, Central Italy, straddling the Arno just before it empties into the Ligurian Sea. It is the capital city of the Province of Pisa. Although Pisa is known worldwide for the Leaning Tower of Pisa, the city contains more than twenty other historic churches, several medieval palaces, and bridges across the Arno. Much of the city's architecture was financed from its history as one of the Italian maritime republics. The city is also home to the University of Pisa, which has a history going back to the 12th century, the Scuola Normale Superiore di Pisa, founded by Napoleon in 1810, and its offshoot, the Sant'Anna School of Advanced Studies.Scuola Superiore Sant'Anna di Pisa
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Sassari
Sassari ( ; ; ; ) is an Italian city and the second-largest of Sardinia in terms of population with 120,497 inhabitants as of 2025, and a functional urban area of about 260,000 inhabitants. One of the oldest cities on the island, it contains a considerable collection of art. Since its origins at the turn of the 12th century, Sassari has been ruled by the Giudicato of Torres, the Pisans, as an independent republic in alliance with Republic of Genoa, Genoa, by the Crown of Aragon, Aragonese and the Spain, Spanish, all of whom have contributed to Sassari's historical and artistic heritage. Sassari is a city rich in art, culture and history, and is well known for its palazzo, palazzi, the Fountain of the Rosello, and its elegant neoclassical architecture, such as Piazza d'Italia (Italy Square) and the Teatro Civico (Civic Theatre). As Sardinia's second most populated city, it has a considerable amount of cultural, touristic, commercial and political importance in the island. The ...
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