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Gertrud Hurler
Gertrud Hurler, née Zach (1 September 1889 – 1965), was a German pediatrician who wrote up a disease that came to be known as Hurler syndrome and a lesser version which is known as Hurler–Scheie syndrome. Life Gertrud Hurler was born in Taberwiese, East Prussia, German Empire (now Taborzec, Poland) on 1 September 1889. She was educated in Königsberg, East Prussia (now Kaliningrad, Russia), before getting her M.D. degree at the University of Munich. She married Konrad Hurler, a veterinary surgeon, in 1914 and they had a daughter and a son together. Her example inspired her husband to get his own medical certificate. During her post-graduate training in pediatrics at Hauner Children's Hospital, she observed two infants that displayed symptoms of corneal clouding, dwarfing skeletal dysplasia, spinal misalignment, and mental retardation. Previously known as gargoylism or lipochondrodystrophy, the disease was named after her, despite the initial report being given by her chief ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Taberwiese
Taborzec is a village in the administrative district of Gmina Barciany, within Kętrzyn County, Warmian-Masurian Voivodeship, in northern Poland, close to the border with the Kaliningrad Oblast of Russia. It lies approximately south of Barciany, north of Kętrzyn, and north-east of the regional capital Olsztyn. References Villages in Kętrzyn County, Taborzec {{Kętrzyn-geo-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Veterinary Surgeon
Veterinary surgery is surgery performed on animals by veterinarians, whereby the procedures fall into three broad categories: orthopaedics (bones, joints, muscles), soft tissue surgery (skin, body cavities, cardiovascular system, GI/urogenital/respiratory tracts), and neurosurgery. Advanced surgical procedures such as joint replacement (total hip, knee and elbow replacement), fracture repair, stabilization of cranial cruciate ligament deficiency, oncologic (cancer) surgery, herniated disc treatment, complicated gastrointestinal or urogenital procedures, kidney transplant, skin grafts, complicated wound management, and minimally invasive procedures (arthroscopy, laparoscopy, thoracoscopy) are performed by veterinary surgeons (as registered in their jurisdiction). Most general practice veterinarians perform routine surgeries such as neuters and minor mass excisions; some also perform additional procedures. The goal of veterinary surgery may be quite different in pets and in farm ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1965 Deaths
Events January–February * January 14 – The Prime Minister of Northern Ireland and the Taoiseach of the Republic of Ireland meet for the first time in 43 years. * January 20 ** Lyndon B. Johnson is Second inauguration of Lyndon B. Johnson, sworn in for a full term as President of the United States. ** Indonesian President Sukarno announces the withdrawal of the Indonesian government from the United Nations. * January 30 – The Death and state funeral of Winston Churchill, state funeral of Sir Winston Churchill takes place in London with the largest assembly of dignitaries in the world until the 2005 funeral of Pope John Paul II. * February 4 – Trofim Lysenko is removed from his post as director of the Institute of Genetics at the Russian Academy of Sciences, Academy of Sciences in the Soviet Union. Lysenkoism, Lysenkoist theories are now treated as pseudoscience. * February 12 ** The African and Malagasy Republic, Malagasy Common Organization ('; OCA ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1889 Births
Events January–March * January 1 ** The total solar eclipse of January 1, 1889 is seen over parts of California and Nevada. ** Paiute spiritual leader Wovoka experiences a vision, leading to the start of the Ghost Dance movement in the Dakotas. * January 4 – An Act to Regulate Appointments in the Marine Hospital Service of the United States is signed by President Grover Cleveland. It establishes a Commissioned Corps of officers, as a predecessor to the modern-day U.S. Public Health Service Commissioned Corps. * January 5 – Preston North End F.C. is declared the winner of the inaugural Football League in England. * January 8 – Herman Hollerith receives a patent for his electric tabulating machine in the United States. * January 15 – The Coca-Cola Company is originally incorporated as the Pemberton Medicine Company in Atlanta, Georgia. * January 22 – Columbia Phonograph is formed in Washington, D.C. * January 30 – Rudolf, Crown Prince of Austria a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Munich Pediatric Society
Munich ( ; german: München ; bar, Minga ) is the capital and most populous city of the German state of Bavaria. With a population of 1,558,395 inhabitants as of 31 July 2020, it is the third-largest city in Germany, after Berlin and Hamburg, and thus the largest which does not constitute its own state, as well as the 11th-largest city in the European Union. The city's metropolitan region is home to 6 million people. Straddling the banks of the River Isar (a tributary of the Danube) north of the Bavarian Alps, Munich is the seat of the Bavarian administrative region of Upper Bavaria, while being the most densely populated municipality in Germany (4,500 people per km2). Munich is the second-largest city in the Bavarian dialect area, after the Austrian capital of Vienna. The city was first mentioned in 1158. Catholic Munich strongly resisted the Reformation and was a political point of divergence during the resulting Thirty Years' War, but remained physically unto ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mental Retardation
Intellectual disability (ID), also known as general learning disability in the United Kingdom and formerly mental retardation, Rosa's Law, Pub. L. 111-256124 Stat. 2643(2010). is a generalized neurodevelopmental disorder characterized by significantly impaired intellectual and adaptive functioning. It is defined by an IQ under 70, in addition to deficits in two or more adaptive behaviors that affect everyday, general living. Intellectual functions are defined under DSM-V as reasoning, problem‑solving, planning, abstract thinking, judgment, academic learning, and learning from instruction and experience, and practical understanding confirmed by both clinical assessment and standardized tests. Adaptive behavior is defined in terms of conceptual, social, and practical skills involving tasks performed by people in their everyday lives. Intellectual disability is subdivided into syndromic intellectual disability, in which intellectual deficits associated with other medical and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dysplasia
Dysplasia is any of various types of abnormal growth or development of cells ( microscopic scale) or organs (macroscopic scale), and the abnormal histology or anatomical structure(s) resulting from such growth. Dysplasias on a mainly microscopic scale include epithelial dysplasia and fibrous dysplasia of bone. Dysplasias on a mainly macroscopic scale include hip dysplasia, myelodysplastic syndrome, and multicystic dysplastic kidney. In one of the modern histopathological senses of the term, dysplasia is sometimes differentiated from other categories of tissue change including hyperplasia, metaplasia, and neoplasia, and dysplasias are thus generally not cancerous. An exception is that the myelodysplasias include a range of benign, precancerous, and cancerous forms. Various other dysplasias tend to be precancerous. The word's meanings thus cover a spectrum of histopathological variations. Microscopic scale Epithelial dysplasia Epithelial dysplasia consists of an exp ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cornea
The cornea is the transparent front part of the eye that covers the iris, pupil, and anterior chamber. Along with the anterior chamber and lens, the cornea refracts light, accounting for approximately two-thirds of the eye's total optical power. In humans, the refractive power of the cornea is approximately 43 dioptres. The cornea can be reshaped by surgical procedures such as LASIK. While the cornea contributes most of the eye's focusing power, its focus is fixed. Accommodation (the refocusing of light to better view near objects) is accomplished by changing the geometry of the lens. Medical terms related to the cornea often start with the prefix "'' kerat-''" from the Greek word κέρας, ''horn''. Structure The cornea has unmyelinated nerve endings sensitive to touch, temperature and chemicals; a touch of the cornea causes an involuntary reflex to close the eyelid. Because transparency is of prime importance, the healthy cornea does not have or need blood vess ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Königsberg
Königsberg (, ) was the historic Prussian city that is now Kaliningrad, Russia. Königsberg was founded in 1255 on the site of the ancient Old Prussian settlement ''Twangste'' by the Teutonic Knights during the Northern Crusades, and was named in honour of King Ottokar II of Bohemia. A Baltic port city, it successively became the capital of the Królewiec Voivodeship, the State of the Teutonic Order, the Duchy of Prussia and the provinces of East Prussia and Prussia. Königsberg remained the coronation city of the Prussian monarchy, though the capital was moved to Berlin in 1701. Between the thirteenth and the twentieth centuries, the inhabitants spoke predominantly German, but the multicultural city also had a profound influence upon the Lithuanian and Polish cultures. The city was a publishing center of Lutheran literature, including the first Polish translation of the New Testament, printed in the city in 1551, the first book in Lithuanian and the first Lutheran ca ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
East Prussia
East Prussia ; german: Ostpreißen, label= Low Prussian; pl, Prusy Wschodnie; lt, Rytų Prūsija was a province of the Kingdom of Prussia from 1773 to 1829 and again from 1878 (with the Kingdom itself being part of the German Empire from 1871); following World War I it formed part of the Weimar Republic's Free State of Prussia, until 1945. Its capital city was Königsberg (present-day Kaliningrad). East Prussia was the main part of the region of Prussia along the southeastern Baltic Coast. The bulk of the ancestral lands of the Baltic Old Prussians were enclosed within East Prussia. During the 13th century, the native Prussians were conquered by the crusading Teutonic Knights. After the conquest the indigenous Balts were gradually converted to Christianity. Because of Germanization and colonisation over the following centuries, Germans became the dominant ethnic group, while Masurians and Lithuanians formed minorities. From the 13th century, East Prussia was pa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hurler–Scheie Syndrome
Hurler–Scheie syndrome is a genetic disorder caused by the buildup of glycosaminoglycans (GAGs) in various organ tissues. It is a cutaneous condition, also characterized by mild mental retardation and corneal clouding. Respiratory problems, sleep apnea, and heart disease may develop in adolescence. Hurler–Scheie syndrome is classified as a lysosomal storage disease. Patients with Hurler–Scheie syndrome lack the ability to break down GAGs in their lysosomes due a deficiency of the enzyme iduronidase. All forms of mucopolysaccharidosis type I (MPS I) are a spectrum of the same disease. Hurler-Sheie is the subtype of MPS I with intermediate severity. Hurler syndrome is the most severe form, while Scheie syndrome is the least severe form. Some clinicians consider the differences between Hurler, Hurler-Scheie, and Scheie syndromes to be arbitrary. Instead, they classify these patients as having "severe", "intermediate", or "attenuated" MPS I. See also * Mucopolysaccharidosis ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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