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Geriatric Psychiatry
Geriatric psychiatry, also known as geropsychiatry, psychogeriatrics or psychiatry of old age, is a branch of medicine and a subspecialty of psychiatry dealing with the study, prevention, and treatment of neurodegenerative, cognitive impairment, and mental disorders in people of old age.Barraclough, J.; Gill, D. (1996). ''Hughes' outline of modern psychiatry''. (4th ed.) New York: John Wiley & Sons. Bowden, V.M.; Long, M.J. (1995). Geriatric psychiatry. ''Journal of the American Medical Association, 273'', 1395. Geriatric psychiatry as a subspecialty has significant overlap with the specialties of geriatric medicine, behavioural neurology, neuropsychiatry, neurology, and general psychiatry. Geriatric psychiatry has become an official subspecialty of psychiatry with a defined curriculum of study and core competencies. History Origins The origins of geriatric psychiatry began with Alois Alzheimer, a German psychiatrist and neuropathologist who first identified amyloi ...
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Nervous System
In biology, the nervous system is the complex system, highly complex part of an animal that coordinates its behavior, actions and sense, sensory information by transmitting action potential, signals to and from different parts of its body. The nervous system detects environmental changes that impact the body, then works in tandem with the endocrine system to respond to such events. Nervous tissue first arose in Ediacara biota, wormlike organisms about 550 to 600 million years ago. In Vertebrate, vertebrates, it consists of two main parts, the central nervous system (CNS) and the peripheral nervous system (PNS). The CNS consists of the brain and spinal cord. The PNS consists mainly of nerves, which are enclosed bundles of the long fibers, or axons, that connect the CNS to every other part of the body. Nerves that transmit signals from the brain are called motor nerves (efferent), while those nerves that transmit information from the body to the CNS are called sensory nerves (aff ...
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Cognitive Impairment
Cognitive impairment is an inclusive term to describe any characteristic that acts as a barrier to the cognition process or different areas of cognition. Cognition, also known as cognitive function, refers to the mental processes of how a person gains knowledge, uses existing knowledge, and understands things that are happening around them using their thoughts and senses. Cognitive impairment can be in different domains or aspects of a person's cognitive function including memory, attention span, planning, reasoning, decision-making, language (comprehension, writing, speech), executive functioning, and visuospatial functioning. The term cognitive impairment covers many different diseases and conditions and may also be symptom or manifestation of a different underlying condition. Examples include impairments in overall intelligence (as with intellectual disabilities), specific and restricted impairments in cognitive abilities (such as in learning disorders like dyslexia), neurops ...
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Neurofibrillary Tangles
Neurofibrillary tangles (NFTs) are intracellular aggregates of hyperphosphorylated tau protein that are most commonly known as a primary Biomarker (medicine), biomarker of Alzheimer's disease. Their presence is also found in numerous other diseases known as Tauopathy, tauopathies. Little is known about their exact relationship to the different pathologies. Formation Neurofibrillary tangles are formed by phosphorylation, hyperphosphorylation of a microtubule-associated protein known as tau (protein), tau, causing it to aggregate, or group, in an insoluble form. (These aggregations of hyperphosphorylated tau protein are also referred to as PHF, or "paired helical filaments"). The precise mechanism of tangle formation is not completely understood, though it is typically recognized that tangles are a primary causative factor in neurodegenerative disease. Cytoskeletal changes Three different maturation states of NFT have been defined using anti-tau and anti-ubiquitin immunostaining. ...
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Amyloid
Amyloids are aggregates of proteins characterised by a fibrillar morphology of typically 7–13 nm in diameter, a β-sheet secondary structure (known as cross-β) and ability to be stained by particular dyes, such as Congo red. In the human body, amyloids have been linked to the development of various diseases. Pathogenic amyloids form when previously healthy proteins lose their normal structure and physiological functions ( misfolding) and form fibrous deposits within and around cells. These protein misfolding and deposition processes disrupt the healthy function of tissues and organs. Such amyloids have been associated with (but not necessarily as the cause of) more than 50 human diseases, known as amyloidosis, and may play a role in some neurodegenerative diseases. Some of these diseases are mainly sporadic and only a few cases are familial. Others are only familial. Some result from medical treatment. Prions are an infectious form of amyloids that can act as a templa ...
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Neuropathologist
Neuropathology is the study of disease of nervous system tissue, usually in the form of either small surgical biopsies or whole-body autopsies. Neuropathologists usually work in a department of anatomic pathology, but work closely with the clinical disciplines of neurology, and neurosurgery, which often depend on neuropathology for a diagnosis. Neuropathology also relates to forensic pathology because brain disease or brain injury can be related to cause of death. Neuropathology should not be confused with neuropathy, which refers to disorders of the nerves themselves (usually in the peripheral nervous system) rather than the tissues. In neuropathology, the branches of the specializations of nervous system as well as the tissues come together into one field of study. Methodology The work of the neuropathologist consists largely of examining autopsy or biopsy tissue from the brain and spinal cord to aid in diagnosis of disease. In addition to brain and spinal cord, tissues of ...
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Psychiatrist
A psychiatrist is a physician who specializes in psychiatry. Psychiatrists are physicians who evaluate patients to determine whether their symptoms are the result of a physical illness, a combination of physical and mental ailments or strictly mental issues. Sometimes a psychiatrist works within a multi-disciplinary team, which may comprise clinical psychologists, social workers, occupational therapists, and nursing staff. Psychiatrists have broad training in a biopsychosocial approach to the assessment and management of mental illness. As part of the clinical assessment process, psychiatrists may employ a mental status examination; a physical examination; brain imaging such as a computerized tomography, magnetic resonance imaging, or positron emission tomography scan; and blood testing. Psychiatrists use pharmacologic, psychotherapeutic, or interventional approaches to treat mental disorders. Subspecialties The field of psychiatry has many subspecialties that ...
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German Empire
The German Empire (),; ; World Book, Inc. ''The World Book dictionary, Volume 1''. World Book, Inc., 2003. p. 572. States that Deutsches Reich translates as "German Realm" and was a former official name of Germany. also referred to as Imperial Germany, the Second Reich or simply Germany, was the period of the German Reich; . from the unification of Germany in 1871 until the German revolution of 1918–1919, November Revolution in 1918, when the German Reich changed its form of government from a monarchy to a Weimar Republic, republic. The German Empire consisted of States of the German Empire, 25 states, each with its own nobility: four constituent Monarchy, kingdoms, six Grand duchy, grand duchies, five Duchy, duchies (six before 1876), seven Principality, principalities, three Free imperial city, free Hanseatic League, Hanseatic City-state, cities, and Alsace–Lorraine, one imperial territory. While Prussia was one of four kingdoms in the realm, it contained about two-thirds ...
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Alois Alzheimer
Alois Alzheimer ( , , ; 14 June 1864 – 19 December 1915) was a German psychiatrist, neuropathologist and colleague of Emil Kraepelin. He is credited with identifying the first published case of "presenile dementia", which Kraepelin later identified as Alzheimer's disease. Early life and education Alzheimer was born in Marktbreit, Kingdom of Bavaria, Bavaria, on 14 June 1864, the son of Anna Johanna Barbara Sabina and Eduard Román Alzheimer. His father served in the office of notary public in the family's hometown. The family was devoutly Catholic Church, Catholic. The Alzheimers moved to Aschaffenburg when Alois was still young in order to give their children an opportunity to attend the Royal Humanistic Gymnasium (high school). After graduating with Abitur in 1883, Alzheimer studied medicine at Humboldt University Berlin, University of Berlin, University of Tübingen, and University of Würzburg. In his final year at university, he was a member of a fencing Studentenverbi ...
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Alois Alzheimer 003
Alois (Latinized ''Aloysius'') is an Old Occitan form of the name Louis. Modern variants include ''Aloïs'' ( French), ''Aloys'' (German), ''Alois'' (Czech), '' Alojz'' ( Slovak, Slovenian, Croatian), '' Alojzy'' ( Polish), '' Aloísio'' ( Portuguese, Spanish, Italian), '' Alajos'' ( Hungarian), and '' Aloyzas'' ( Lithuanian). People called Alois/Aloys * Alois Alzheimer (1864–1915), German psychiatrist and neuropathologist * Alois Arnegger (1879–1963), Austrian painter * Alois Berla (1826–1896), Austrian actor and playwright * Alois Biach (1849–1918), Austrian physician and medical writer * Alois Brunner (1912–2001), Austrian Nazi SS concentration camp war criminal * Alois Carigiet (1902–1985), Swiss illustrator * Alois Dryák (1872–1932), Czech architect * Alois Eliáš (1890–1942), Czech general and politician * Alois Estermann, senior officer of the Pontifical Swiss Guard who was murdered in his apartment * Alois Hába, Czech composer * Alois Hitler (1837– ...
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Neurology
Neurology (from , "string, nerve" and the suffix wikt:-logia, -logia, "study of") is the branch of specialty (medicine) , medicine dealing with the diagnosis and treatment of all categories of conditions and disease involving the nervous system, which comprises the Human brain, brain, the spinal cord and the peripheral nervous system , peripheral nerves. Neurological practice relies heavily on the field of neuroscience, the scientific study of the nervous system, using various techniques of neurotherapy. IEEE Brain (2019). "Neurotherapy: Treating Disorders by Retraining the Brain". ''The Future Neural Therapeutics White Paper''. Retrieved 23.01.2025 from: https://brain.ieee.org/topics/neurotherapy-treating-disorders-by-retraining-the-brain/#:~:text=Neurotherapy%20trains%20a%20patient's%20brain,wave%20activity%20through%20positive%20reinforcement International Neuromodulation Society, Retrieved 23 January 2025 from: https://www.neuromodulation.com/ Val Danilov I (2023). "The O ...
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Neuropsychiatry
Neuropsychiatry is a branch of medicine that deals with psychiatry as it relates to neurology, in an effort to understand and attribute behavior to the interaction of neurobiology and social psychology factors. Within neuropsychiatry, the mind is considered "as an emergent property of the brain", whereas other behavioral and neurological specialties might consider the two as separate entities. Those disciplines are typically practiced separately. Currently, neuropsychiatry has become a growing subspecialty of psychiatry as it closely relates the fields of neuropsychology and behavioral neurology, and attempts to utilize this understanding to better understand autism, attention deficit hyperactivity disorder (ADHD), and Tourette syndrome, among others. The case for the rapprochement of neurology and psychiatry Given the considerable overlap between these subspecialities, there has been a resurgence of interest and debate relating to neuropsychiatry in academia over the last deca ...
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Behavioural Neurology
Behavioral neurology is a subspecialty of neurology that studies the impact of neurological damage and disease upon behavior, memory, and cognition, and the treatment thereof. Two fields associated with behavioral neurology are neuropsychiatry and neuropsychology. In the United States, 'Behavioral Neurology & Neuropsychiatry' has been recognized as a single subspecialty by the United Council for Neurologic Subspecialties (UCNS) since 2004. Syndromes and diseases commonly studied by behavioral neurology include: * Agraphia * Agnosias * Agraphesthesia * Alexia (acquired dyslexia) * Amnesias * Anosognosia * Aphasias * Apraxias * Aprosodias * Attention deficit/hyperactivity disorder * Autism * Dementia * Dyslexia * Epilepsy * Hemispatial Neglect * Psychosis * Stroke * Traumatic brain injury History While descriptions of behavioral syndromes go back to the ancient Greeks and Egyptians, it was during the 19th century that behavioral neurology began to arise, first with the pri ...
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