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Gerbil Scheme
The Mongolian gerbil or Mongolian jird (''Meriones unguiculatus'') is a rodent belonging to the subfamily Gerbillinae. Their body size is typically , with a tail, and body weight , with adult males larger than females. The animal is used in science and research or kept as a small house pet. Their use in science dates back to the latter half of the 19th century, but they only started to be kept as pets in the English-speaking world after 1954, when they were brought to the United States. However, their use in scientific research has fallen out of favor. Taxonomy and evolution The first known mention of gerbils came in 1866, by Father Armand David, who sent "yellow rats" to the French National Museum of Natural History in Paris, from northern China. They were named ''Gerbillus unguiculatus'' by the scientist Alphonse Milne-Edwards in 1867. There is a popular misconception about the meaning of this scientific name, appearing both in printed works and in websites, due to the ...
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Alphonse Milne-Edwards
Alphonse Milne-Edwards (Paris, 13 October 1835 – Paris, 21 April 1900) was a French mammalogist, ornithologist, and carcinologist. He was English in origin, the son of Henri Milne-Edwards and grandson of Bryan Edwards, a Jamaican planter who settled at Bruges (then in France). Milne-Edwards obtained a medical degree in 1859 and became assistant to his father at the ' in 1876. He became the director of the in 1891, devoting himself especially to fossil birds and deep-sea exploration. In 1881, he undertook a survey of the Gulf of Gascony with Léopold de Folin and worked aboard the ''Travailleur'' and the '' Talisman,'' researching the seas off the Canary Islands, the Cape Verde Islands, and the Azores. For this, he received a gold medal of the Royal Geographical Society. His major ornithological works include ' published in two parts in 1867 and 1872, ' 1866–1874 and ' 1868–1874. His study of fossils led to the discovery of tropical birds such as trogons and parrots ...
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Estrus
The estrous cycle (, originally ) is a set of recurring physiological changes induced by reproductive hormones in females of mammalian subclass Theria. Estrous cycles start after sexual maturity in females and are interrupted by anestrous phases, otherwise known as "rest" phases, or by pregnancies. Typically, estrous cycles repeat until death. These cycles are widely variable in duration and frequency depending on the species.Bronson, F. H., 1989. Mammalian Reproductive Biology. University of Chicago Press, Chicago, IL, USA. Some animals may display bloody vaginal discharge, often mistaken for menstruation. Many mammals used in commercial agriculture, such as cattle and sheep, may have their estrous cycles artificially controlled with hormonal medications for optimum productivity. The male equivalent, seen primarily in ruminants, is called rut. Differences from the menstrual cycle Mammals share the same reproductive system, including the regulatory hypothalamic system tha ...
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Genetic Marker
A genetic marker is a gene or DNA sequence with a known location on a chromosome that can be used to identify individuals or species. It can be described as a variation (which may arise due to mutation or alteration in the genomic loci) that can be observed. A genetic marker may be a short DNA sequence, such as a sequence surrounding a single base-pair change ( single nucleotide polymorphism, SNP), or a long one, like minisatellites. Background For many years, gene mapping was limited to identifying organisms by traditional phenotypes markers. This included genes that encoded easily observable characteristics, such as blood types or seed shapes. The insufficient number of these types of characteristics in several organisms limited the possible mapping efforts. This prompted the development of gene markers, which could identify genetic characteristics that are not readily observable in organisms (such as protein variation). Types Some commonly used types of genetic markers ar ...
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Diabetes Mellitus Type 2
Type 2 diabetes (T2D), formerly known as adult-onset diabetes, is a form of diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin. Common symptoms include increased thirst, frequent urination, fatigue and unexplained weight loss. Other symptoms include increased hunger, having a sensation of pins and needles, and sores (wounds) that heal slowly. Symptoms often develop slowly. Long-term complications from high blood sugar include heart disease, stroke, diabetic retinopathy, which can result in blindness, kidney failure, and poor blood flow in the lower limbs, which may lead to amputations. A sudden onset of hyperosmolar hyperglycemic state may occur; however, ketoacidosis is uncommon. Type 2 diabetes primarily occurs as a result of obesity and lack of exercise. Some people are genetically more at risk than others. Type 2 diabetes makes up about 90% of cases of diabetes, with the other 10% due primaril ...
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Fat Sand Rat
The fat sand rat (''Psammomys obesus'') is a terrestrial mammal from the Gerbillinae, gerbil subfamily that is mostly found in North Africa and the Middle East, ranging from Mauritania to the Arabian Peninsula. This species usually lives in sandy deserts, but may also be found in rocky terrain or saline marsh areas. Fat sand rats are very selective in their diet, only eating stems and leaves of plants from the family Amaranthaceae, more commonly known as the amaranth family. In captivity, fat sand rats can become obese and rapidly develop diabetes-like symptoms when fed the diet typically given to other rodents. ''P. obesus'' has an average lifespan of 14 months in the wild and 3–4 years in captivity. Ecology Activity patterns The fat sand rat is Diurnality, diurnal, but its activity on the surface fluctuates depending on the ambient temperature. Its period of activity is shortest in the summer, starting in the early morning and finishing an hour to several hours after. As ...
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Seizure
A seizure is a sudden, brief disruption of brain activity caused by abnormal, excessive, or synchronous neuronal firing. Depending on the regions of the brain involved, seizures can lead to changes in movement, sensation, behavior, awareness, or consciousness. Symptoms vary widely. Some seizures involve subtle changes, such as brief lapses in attention or awareness (as seen in absence seizures), while others cause generalized convulsions with loss of consciousness ( tonic–clonic seizures). Most seizures last less than two minutes and are followed by a postictal period of confusion, fatigue, or other symptoms. A seizure lasting longer than five minutes is a medical emergency known as status epilepticus. Seizures are classified as provoked, when triggered by a known cause such as fever, head trauma, or metabolic imbalance, or unprovoked, when no immediate trigger is identified. Recurrent unprovoked seizures define the neurological condition epilepsy. Clinical features Seizur ...
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Epilepsy
Epilepsy is a group of Non-communicable disease, non-communicable Neurological disorder, neurological disorders characterized by a tendency for recurrent, unprovoked Seizure, seizures. A seizure is a sudden burst of abnormal electrical activity in the brain that can cause a variety of symptoms, ranging from brief lapses of awareness or muscle jerks to prolonged convulsions. These episodes can result in physical injuries, either directly, such as broken bones, or through causing accidents. The diagnosis of epilepsy typically requires at least two unprovoked seizures occurring more than 24 hours apart. In some cases, however, it may be diagnosed after a single unprovoked seizure if clinical evidence suggests a high risk of recurrence. Isolated seizures that occur without recurrence risk or are provoked by identifiable causes are not considered indicative of epilepsy. The underlying cause is often unknown, but epilepsy can result from brain injury, stroke, infections, Brain tumor, ...
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Rattus Rattus Domesticus
''Rattus'' is a genus of muroid rodents, all typically called rats. However, the term rat can also be applied to rodent species outside of this genus. Species and description The best-known ''Rattus'' species are the black rat (''R. rattus'') and the brown rat (''R. norvegicus''). The group is generally known as the Old World rats or true rats and originated in Asia. Rats are bigger than most Old World mice, which are their relatives, but seldom weigh over in the wild. Taxonomy of ''Rattus'' The genus ''Rattus'' is a member of the giant subfamily Murinae. Several other murine genera are sometimes considered part of ''Rattus'': ''Lenothrix'', '' Anonymomys'', ''Sundamys'', ''Kadarsanomys'', '' Diplothrix'', ''Margaretamys'', '' Lenomys'', ''Komodomys'', '' Palawanomys'', ''Bunomys'', ''Nesoromys'', ''Stenomys'', '' Taeromys'', '' Paruromys'', ''Abditomys'', '' Tryphomys'', ''Limnomys'', '' Tarsomys'', ''Bullimus'', '' Apomys'', '' Millardia'', '' Srilankamys'', ''Niviventer'', ...
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Hearing Loss
Hearing loss is a partial or total inability to hear. Hearing loss may be present at birth or acquired at any time afterwards. Hearing loss may occur in one or both ears. In children, hearing problems can affect the ability to acquire spoken language, and in adults it can create difficulties with social interaction and at work. Hearing loss can be temporary or permanent. Hearing loss related to age usually affects both ears and is due to cochlear hair cell loss. In some people, particularly older people, hearing loss can result in loneliness. Hearing loss may be caused by a number of factors, including: genetics, ageing, exposure to noise, some infections, birth complications, trauma to the ear, and certain medications or toxins. A common condition that results in hearing loss is chronic ear infections. Certain infections during pregnancy, such as cytomegalovirus, syphilis and rubella, may also cause hearing loss in the child. Hearing loss is diagnosed when hearing ...
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Charles River Laboratories
Charles River Laboratories International, Inc. is an American pharmaceutical company specializing in preclinical and clinical laboratory, gene therapy and cell therapy services and supplies for the pharmaceutical, medical device and biotechnology industries. The company has over 150 facilities, operates in 21 countries, and employs over 21,000 people worldwide. Charles River Laboratories frequently criticized by animal rights activists, who condemn the company's use of dogs and primates for pharmaceutical research. The company is also a major harvester of blood from horseshoe crabs. History Charles River was founded in 1947 by Henry Foster, a young veterinarian who purchased one thousand rat cages from a Virginia farm and set up a one-person laboratory in Boston overlooking the Charles River. He supplied local researchers with laboratory animal models. In 1955, the company's headquarters were relocated to their current home in Wilmington, Massachusetts. The organization b ...
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United States
The United States of America (USA), also known as the United States (U.S.) or America, is a country primarily located in North America. It is a federal republic of 50 U.S. state, states and a federal capital district, Washington, D.C. The 48 contiguous states border Canada to the north and Mexico to the south, with the semi-exclave of Alaska in the northwest and the archipelago of Hawaii in the Pacific Ocean. The United States asserts sovereignty over five Territories of the United States, major island territories and United States Minor Outlying Islands, various uninhabited islands in Oceania and the Caribbean. It is a megadiverse country, with the world's List of countries and dependencies by area, third-largest land area and List of countries and dependencies by population, third-largest population, exceeding 340 million. Its three Metropolitan statistical areas by population, largest metropolitan areas are New York metropolitan area, New York, Greater Los Angeles, Los Angel ...
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Brant Lake, New York
Brant Lake is a hamlet in the town of Horicon in Warren County, New York, United States. It is located approximately halfway between Albany to the south and Plattsburgh to the north. History Since the mid-1880s, Brant Lake has been a popular fishing and hunting area among wealthy visitors, including Theodore Roosevelt. ''Circa'' 1900, several hotels began catering to these wealthy visitors. Summer camps for youth were established around the same time. Brant Lake Camp was incorporated by R.B. Gerstenzang, J.E. Eberly, and John F. Malloy in 1917. The camp was featured in '' Town & Country'' magazine. Brant Lake Lodge was one of oldest hotels in the area of the Adirondacks The Adirondack Mountains ( ) are a massif of mountains in Northeastern New York (state), New York which form a circular dome approximately wide and covering about . The region contains more than 100 peaks, including Mount Marcy, which is the hi ...; it burned down in April 1925. Brant Lake has had a ...
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