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George Lignac
George Otto Emil Lignac (30 August 1891 – 5 September 1954) was a Dutch pathologist-anatomist. Lignac was born in Passoeroean, Java, Dutch East Indies, where his father worked as a civil servant. He studied medicine at Leiden and then returned to the Dutch East Indies and was a teacher at the STOVIA (''School tot Opleiding van Indische Artsen'' or "school for the training of Indian physicians") in Batavia. He returned to the Netherlands and was appointed professor of pathology, general diseases, pathological anatomy, and juridical medicine in Leiden in 1934. He published work on skin pigmentation, cysteine metabolism and the carcinogenic nature of benzol and many more. The Abderhalden–Kaufmann–Lignac syndrome is named for Emil Abderhalden, Eduard Kaufmann and George Lignac. Renal Fanconi syndrome has sometimes been called Lignac–Fanconi syndrome, as Lignac contributed to the study of it. Lignac died in a plane crash An aviation accident is an event during ai ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pasuruan
Pasuruan () is a city in East Java Province of Java, Indonesia. It had a population of 186,262 at the 2010 CensusBiro Pusat Statistik, Jakarta, 2011. and 208,006 at the 2020 Census;Badan Pusat Statistik, Jakarta, 2021. the official estimate as at mid 2023 was 212,466 (comprising 106,294 males and 106,172 females).Badan Pusat Statistik, Jakarta, 28 February 2024, ''Kota Pasuruan Dalam Angka 2024'' (Katalog-BPS 1102001.3575) It is surrounded on the landward side by, but is administratively separate from, Pasuruan Regency. On the north side it faces onto the Madura Strait. It is located around 65 kilometres southeast of Surabaya, the provincial capital. Administrative districts Pasuruan is divided into four districts (''kecamatan''), tabulated below with their areas and their populations at the 2010Biro Pusat Statistik, Jakarta, 2011. and 2020Badan Pusat Statistik, Jakarta, 2021. Censuses, together with the official estimates as at mid 2023.Badan Pusat Statistik, Jakarta, 28 Febru ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cysteine
Cysteine (; symbol Cys or C) is a semiessential proteinogenic amino acid with the chemical formula, formula . The thiol side chain in cysteine enables the formation of Disulfide, disulfide bonds, and often participates in enzymatic reactions as a nucleophile. Cysteine is chiral, but both D and L-cysteine are found in nature. LCysteine is a protein monomer in all biota, and D-cysteine acts as a signaling molecule in mammalian nervous systems. Cysteine is named after its discovery in urine, which comes from the urinary bladder or cyst, from Ancient Greek, Greek κύστις ''kýstis'', "bladder". The thiol is susceptible to oxidation to give the disulfide bond, disulfide derivative cystine, which serves an important structural role in many proteins. In this case, the symbol Cyx is sometimes used. The deprotonated form can generally be described by the symbol Cym as well. When used as a food additive, cysteine has the E number E920. Cysteine is Genetic code, encoded by the codo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1891 Births
Events January * January 1 ** A strike of 500 Hungarian steel workers occurs; 3,000 men are out of work as a consequence. **Germany takes formal possession of its new African territories. * January 4 – The Earl of Zetland issues a declaration regarding the famine in the western counties of Ireland. * January 5 **The Australian shearers' strike, that leads indirectly to the foundation of the Australian Labor Party, begins. **A fight between the United States and Lakotas breaks out near Pine Ridge agency. **A fight between railway strikers and police breaks out at Motherwell, Scotland. * January 7 ** General Miles' forces surround the Lakota in the Pine Ridge Reservation. ** The Inter-American Monetary Commission meets in Washington DC. * January 9 – The great shoe strike in Rochester, New York is called off. * January 10 – in France, the Irish Nationalist leaders hold a conference at Boulogne. The French government promptly takes loan. * Jan ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Accidents And Incidents In Aviation
An aviation accident is an event during aircraft operation that results serious injury, death, or significant destruction. An aviation incident is any operating event that compromises safety but does not escalate into an aviation accident. Preventing both accidents and incidents is the primary goal of aviation safety. One of the earliest recorded aviation accidents occurred on May 10, 1785, when a hot air balloon crashed in Tullamore, County Offaly, Ireland. The resulting fire seriously damaged the town, destroying over 130 homes. The first accident involving a powered aircraft occurred on September 17, 1908, when a Wright Model A crashed at Fort Myer, Virginia, USA. The pilot and co-inventor, Orville Wright, was injured, and the passenger, Signal Corps Lieutenant Thomas Selfridge, was killed. Definitions According to Annex 13 of the Chicago Convention on International Civil Aviation, Convention on International Civil Aviation, an aviation accident is an occurrence associat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fanconi Syndrome
Fanconi syndrome or Fanconi's syndrome (, ) is a syndrome of inadequate reabsorption in the proximal renal tubules of the kidney. The syndrome can be caused by various underlying congenital or acquired diseases, by toxicity (for example, from toxic heavy metals), or by adverse drug reactions. It results in various small molecules of metabolism being passed into the urine instead of being reabsorbed from the tubular fluid (for example, glucose, amino acids, uric acid, phosphate, and bicarbonate). Fanconi syndrome affects the proximal tubules, namely, the proximal convoluted tubule (PCT), which is the first part of the tubule to process fluid after it is filtered through the glomerulus, and the proximal straight tubule (pars recta), which leads to the descending limb of loop of Henle. Different forms of Fanconi syndrome can affect different functions of the proximal tubule, and result in different complications. The loss of bicarbonate results in type 2 or proximal renal ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Eduard Kaufmann
Eduard Kaufmann (24 March 1860, Bonn – 15 December 1931, Göttingen) was a German physician. The disease Abderhalden–Kaufmann–Lignac syndrome is named for him. Career Kaufmann studied in Bonn and Berlin, and earned his doctorate from the University of Bonn in 1884. He was appointed Privatdozent for anatomical pathology in Breslau three years later, and assisted at Emil Ponfick’s institute. In 1896 Kaufmann became prosector at Allerheiligenhospital in Breslau and professor in 1897. In 1898 he became professor of pathology and anatomical pathology and head of the Pathological Anatomical Institute of the University of Basel. Kaufmann moved in 1907 to Göttingen and finally withdrew from active work in 1927. Kaufmann undertook the first study of cartilage changes in achondroplasia. His first textbook was in pathological anatomy, titled "''Lehrbuch der speciellen pathologischen Anatomie''". He was the author of significant works involving chondrodystrophy and on mali ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Emil Abderhalden
Emil Abderhalden (9 March 1877 – 5 August 1950) was a Swiss biochemist and physiologist. His main findings, though disputed already in the 1910s, were not finally rejected until the late 1990s. Whether his misleading findings were based on fraud or simply the result of a lack of scientific rigour remains unclear. Abderhalden's drying pistol, used in chemistry, was first described by one of his students in a textbook Abderhalden edited. Biography Emil Abderhalden was born in Oberuzwil in the Canton of St. Gallen in Switzerland. He moved to Basel to study at the University of Basel. During his time in Basel, he joined the rowing club and was a founding member of FC Basel. Eleven men attended the meeting of founding Fussball Club Basel on 15 November 1893. Abderhalden played his first game for the club in the home game in the Stadion Schützenmatte on 22 September 1894 as Basel won 2–0 against FC Gymnasia. Abderhalden left the club in January 1895. Abderhalden studied medi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Benzene
Benzene is an Organic compound, organic chemical compound with the Chemical formula#Molecular formula, molecular formula C6H6. The benzene molecule is composed of six carbon atoms joined in a planar hexagonal Ring (chemistry), ring with one hydrogen atom attached to each. Because it contains only carbon and hydrogen atoms, benzene is classed as a hydrocarbon. Benzene is a natural constituent of petroleum and is one of the elementary petrochemicals. Due to the cyclic continuous pi bonds between the carbon atoms, benzene is classed as an aromatic hydrocarbon. Benzene is a colorless and highly Combustibility and flammability, flammable liquid with a sweet smell, and is partially responsible for the aroma of gasoline. It is used primarily as a Precursor (chemistry), precursor to the manufacture of chemicals with more complex structures, such as ethylbenzene and cumene, of which billions of kilograms are produced annually. Although benzene is a major Chemical industry, industrial che ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Human Skin Color
Human skin color ranges from the Dark skin, darkest brown to the Light skin, lightest hues. Differences in Human skin, skin color among individuals is caused by variation in pigmentation, which is largely the result of genetics (inherited from one's biological parents), and in adults in particular, due to Sun tanning, exposure to the sun, disorders, or some combination thereof. Differences across populations evolved through natural selection and sexual selection, because of social norms and differences in environment, as well as regulation of the biochemical effects of ultraviolet radiation penetrating the skin. Human skin color is influenced greatly by the amount of the pigment melanin present. Melanin is produced within the skin in cells called melanocytes; it is the main determinant of the skin color of darker-skin humans. The skin color of people with light skin is determined mainly by the bluish-white connective tissue under the dermis and by the hemoglobin circulating in th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Java (island)
Java is one of the Greater Sunda Islands in Indonesia. It is bordered by the Indian Ocean to the south and the Java Sea (a part of Pacific Ocean) to the north. With a population of 156.9 million people (including Madura) in mid 2024, projected to rise to 158 million at mid 2025, Java is the world's List of islands by population, most populous island, home to approximately 55.7% of the Demographics of Indonesia, Indonesian population (only approximately 44.3% of Indonesian population live outside Java). Indonesia's capital city, Jakarta, is on Java's northwestern coast. Many of the best known events in Indonesian history took place on Java. It was the centre of powerful Hindu-Buddhist empires, the Islamic sultanates, and the core of the colonial Dutch East Indies. Java was also the center of the History of Indonesia, Indonesian struggle for independence during the 1930s and 1940s. Java dominates Indonesia politically, economically and culturally. Four of Indonesia's e ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Forensic Medicine
Forensic medicine is a broad term used to describe a group of medical specialties which deal with the examination and diagnosis of individuals who have been injured by or who have died because of external or unnatural causes such as poisoning, assault, suicide and other forms of violence, and apply findings to law (i.e. court cases). Forensic medicine is a multi-disciplinary branch which includes the practice of forensic pathology, forensic psychiatry, forensic odontology, forensic radiology and forensic toxicology. There are two main categories of forensic medicine; Clinical forensic medicine; Pathological forensics medicine, with the differing factor being the condition of the patients. In clinical forensic medicine it is the investigation of trauma to living patients, whereas pathological forensic medicine involves the examination of traumas to the deceased to find the cause of death. History The term clinical forensic medicine, coined by Thomas Stuart, dates back to the 19th c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
