|
George Larrick
George P. Larrick (November 19, 1901August 11, 1968) was Commissioner of the U.S. Food and Drug Administration (FDA) from 19541965. Early life George P. Larrick was born on November 19, 1901, in Springfield, Ohio. He worked his way through two years at Wittenberg College from 19191921, and then took a pre-medical course at Ohio State University from 19211923. In 1923, he accepted a "temporary job" as a food and drug inspector in Cincinnati, Ohio. Fascinated with the work, he abandoned his medical aspirations, and successfully passed the competitive Civil Service examination for a permanent appointment. By 1930, he had been appointed senior food and drug inspector. In 1937, he was responsible for dispatching very nearly the entire field force of the FDA to track down remnants of the poisonous Elixir Sulfanilamide which killed 109 people, and highlighted the need for pre-market testing of new drugs. Larrick was also responsible for assembling an exhibit, dubbed by reporters, "The Ch ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Commissioner Of Food And Drugs
The United States commissioner of food and drugs is the head of the Food and Drug Administration (FDA), an agency of the United States Department of Health and Human Services. The commissioner is appointed by the president of the United States and must be confirmed by the Senate. The commissioner reports to the secretary of health and human services. Due to frequent controversies involving the FDA, appointments are not always prompt and the agency is often headed by an acting commissioner. For example, Andrew von Eschenbach's appointment was held up by senators who objected to the FDA's refusal to allow emergency contraception to be sold over the counter. The commissioner has frequently been a physician A physician, medical practitioner (British English), medical doctor, or simply doctor is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through the Medical education, study, Med ..., but this is not a requi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Food, Drug, And Cosmetic Act
The United States Federal Food, Drug, and Cosmetic Act (abbreviated as FFDCA, FDCA, or FD&C) is a set of laws passed by the United States Congress in 1938 giving authority to the U.S. Food and Drug Administration (FDA) to oversee the safety of food, drugs, medical devices, and cosmetics. The FDA's principal representative with members of congress during its drafting was Charles W. Crawford. A principal author of this law was Royal S. Copeland, a three-term U.S. senator from New York. In 1968, the Electronic Product Radiation Control provisions were added to the FD&C. Also in that year the FDA formed the Drug Efficacy Study Implementation (DESI) to incorporate into FD&C regulations the recommendations from a National Academy of Sciences investigation of effectiveness of previously marketed drugs. The act has been amended many times, most recently to add requirements about bioterrorism preparations. The introduction of this act was influenced by the death of more than 100 patien ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pan American Health Organization
The Pan American Health Organization (PAHO) is a specialized agency of the United Nations (UN) in charge of international health cooperation in the Americas. It fosters technical cooperation among member countries to fight communicable and noncommunicable diseases, strengthen health systems, and respond to emergencies and disasters. PAHO has 35 Member States and four Associate Members in the region. Headquartered in Washington, D.C., PAHO is the regional office for the World Health Organization in the Americas, and the health organization of the Inter-American System. It is known in Latin America as the OPS () or OPAS (). Description PAHO has scientific and technical expertise at its headquarters, in its 27 country offices, and its three Pan American centers, all working with the countries of the americas in dealing with priority health issues. The health authorities of PAHO's Member States set PAHO's technical and administrative policies through its governing bodies. Th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
John W
John is a common English name and surname: * John (given name) * John (surname) John may also refer to: New Testament Works * Gospel of John, a title often shortened to John * First Epistle of John, often shortened to 1 John * Second Epistle of John, often shortened to 2 John * Third Epistle of John, often shortened to 3 John People * John the Baptist (died ), regarded as a prophet and the forerunner of Jesus Christ * John the Apostle (died ), one of the twelve apostles of Jesus Christ * John the Evangelist, assigned author of the Fourth Gospel, once identified with the Apostle * John of Patmos, also known as John the Divine or John the Revelator, the author of the Book of Revelation, once identified with the Apostle * John the Presbyter, a figure either identified with or distinguished from the Apostle, the Evangelist and John of Patmos Other people with the given name Religious figures * John, father of Andrew the Apostle and Saint Peter * Pope John (disambigu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kefauver Harris Amendment
Carey Estes Kefauver ( ; July 26, 1903 – August 10, 1963) was an American politician from Tennessee. A member of the Democratic Party, he served in the U.S. House of Representatives from 1939 to 1949 and in the U.S. Senate from 1949 until his death in 1963. He was the winner of the 1952 Democratic Party presidential primaries, though he was not nominated at the convention. After leading a much-publicized investigation into organized crime in the early 1950s, he twice sought his party's nomination for President of the United States. In 1956, he was selected by the Democratic National Convention to be the running mate of presidential nominee Adlai Stevenson. He continued to hold his U.S. Senate seat after the Stevenson–Kefauver ticket lost to the Eisenhower–Nixon ticket. Kefauver was named chair of the U.S. Senate Antitrust and Monopoly Subcommittee of the Senate Judiciary Committee in 1957 and served as its chairman until his death. Early life Carey Estes Kefauv ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Drugs In Pregnancy
Women should speak to their doctor or healthcare professional before starting or stopping any medications while pregnant. Drugs taken in pregnancy including over-the counter-medications, prescription medications, nutritional supplements, recreational drugs, and illicit drugs may cause harm to the mother or the unborn child. Non-essential drugs and medications should be avoided while pregnant. Tobacco, alcohol, marijuana, and illicit drug use while pregnant may be dangerous for the unborn baby and may lead to severe health problems and/or birth defects. Even small amounts of alcohol, tobacco, and marijuana have not been proven to be safe when taken while pregnant. In some cases, for example, if the mother has epilepsy or diabetes, the risk of stopping a medication may be worse than risks associated with taking the medication while pregnant. The mother's healthcare professional will help make these decisions about the safest way to protect the health of both the mother and unborn c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Thalidomide
Thalidomide, sold under the brand names Contergan and Thalomid among others, is an oral administered medication used to treat a number of cancers (e.g., multiple myeloma), graft-versus-host disease, and many skin disorders (e.g., complications of leprosy such as skin lesions). Updated as required. Thalidomide has been used to treat conditions associated with HIV: aphthous ulcers, HIV-associated wasting syndrome, diarrhea, and Kaposi's sarcoma, but increases in HIV viral load have been reported. Common side effects include sleepiness, rash, and dizziness. Severe side effects include tumor lysis syndrome, blood clots, and peripheral neuropathy. Thalidomide is a known human teratogen and carries an extremely high risk of severe, life-threatening birth defects if administered or taken during pregnancy. It causes skeletal deformities such as Amelia (birth defect), amelia (absence of legs and/or arms), absence of bones, and phocomelia (malformation of the limbs). A single dose of t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Krebiozen
Krebiozen (aka Carcalon, creatine, substance X, or drug X) is a disproven alternative cancer treatment. While the substance has been marketed as a cure for cancer, originally sold for thousands of dollars per dose in the 1950s and early '60s, Krebiozen is not known to possess any therapeutic value. Attempts to analyze this patent medicine have shown that Krebiozen consists only of the amino acid creatine dissolved in mineral oil, and some samples sold as Krebiozen consist solely of mineral oil with no other discernible ingredients. The American Cancer Society (ACS) states: "Available scientific evidence does not support claims that Krebiozen is effective in treating cancer or any other disease." ACS did not have data on safety but noted that "creatine supplements have been linked with some side effects." History and evaluation Krebiozen was initially promoted by Stevan Durovic, a Yugoslavian physician who claimed that the substance was isolated from the blood serum of horses in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hoxsey Therapy
Hoxsey Therapy or Hoxsey Method is an alternative medical treatment promoted as a cure for cancer. The treatment consists of a caustic herbal paste for external cancers or a herbal mixture for "internal" cancers, combined with laxatives, douches, vitamin supplements, and dietary changes. Reviews by major medical bodies, including the U.S. Food and Drug Administration (FDA), the National Cancer Institute, the American Cancer Society, M. D. Anderson Cancer Center, and Memorial Sloan-Kettering Cancer Center, have found no evidence that Hoxsey Therapy is an effective treatment for cancer. The sale or marketing of the Hoxsey Method was banned in the United States by the FDA on September 21, 1960 as a "worthless and discredited" remedy and a form of quackery. Currently, the Hoxsey Method is primarily marketed by the Bio-Medical Center in Tijuana, Mexico. Hoxsey Therapy is also marketed over the Internet; in June 2008, the FDA National Health Fraud Coordinator noted that "There is no sci ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
3-Amino-1,2,4-triazole
3-Amino-1,2,4-triazole (3-AT) is a heterocyclic organic compound that consists of 1,2,4-triazole with an amino group as a substituent. 3-AT is a competitive inhibitor of the product of the HIS3 gene, imidazoleglycerol-phosphate dehydratase. Imidazoleglycerol-phosphate dehydratase is an enzyme catalyzing the sixth step of histidine production. 3-AT is also a nonselective systemic triazole herbicide used on nonfood croplands to control annual grasses and broadleaf and aquatic weeds. It is not used on food crops because of its carcinogenic properties. As an herbicide, it is known as ''aminotriazole'', ''amitrole'' or ''amitrol''. Amitrol was included in a biocide ban proposed by the Swedish Chemicals Agency and approved by the European Parliament on January 13, 2009. Amitrol's mode of action is unknown, though it is classed as a resistance group Q herbicide. Applications in microbiology By applying 3-AT to a yeast cell culture which is dependent upon a plasmid containing ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
United States House Committee On Appropriations
The United States House Committee on Appropriations is a committee of the United States House of Representatives that is responsible for passing appropriation bills along with its Senate counterpart. The bills passed by the Appropriations Committee regulate expenditures of money by the government of the United States. As such, it is one of the most powerful committees, and its members are seen as influential. History The constitutional basis for the Appropriations Committee comes from Article one, Section nine, Clause seven of the U.S. Constitution, which says: :No money shall be drawn from the treasury, but in consequence of appropriations made by law; and a regular statement and account of receipts and expenditures of all public money shall be published from time to time. This clearly delegated the power of appropriating money to Congress, but was vague beyond that. Originally, the power of appropriating was taken by the Committee on Ways and Means, but the United St ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
John E
John is a common English name and surname: * John (given name) * John (surname) John may also refer to: New Testament Works * Gospel of John, a title often shortened to John * First Epistle of John, often shortened to 1 John * Second Epistle of John, often shortened to 2 John * Third Epistle of John, often shortened to 3 John People * John the Baptist (died ), regarded as a prophet and the forerunner of Jesus Christ * John the Apostle (died ), one of the twelve apostles of Jesus Christ * John the Evangelist, assigned author of the Fourth Gospel, once identified with the Apostle * John of Patmos, also known as John the Divine or John the Revelator, the author of the Book of Revelation, once identified with the Apostle * John the Presbyter, a figure either identified with or distinguished from the Apostle, the Evangelist and John of Patmos Other people with the given name Religious figures * John, father of Andrew the Apostle and Saint Peter * Pope John ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
