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GenePeeks
GenePeeks is a genetic research company that owns and runs ''Matchright'', a simulation that determines the probability of genetic disorders being present in a child given two people's DNA. Overview GenePeeks simulates the combination of genetic sequences of two people and predicts potential diseases and inherited disorders to find good recipient matches for sperm donors. By simulating the process of reproduction with the two DNA sequences, the company's software (called ''Matchright'') forms a hypothetical child genome to determine the likelihood of the resulting child developing one of around 600 conditions. The technology is currently aimed at sperm banks; the first users will be at two fertility clinics in the United States, one of which is Manhattan Cryobank in New York City. The software creates around 10,000 virtual genomes for each donor-recipient pair, and typically rules out 10-15% of donors as bad matches for the recipient. Currently it only searches for single gene ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lee M
Lee Mulhern (born 12 June 1988), now known as Lee Matthews, is an Irish singer-songwriter. Starting age 8, Lee Mulhern (his birth name) had performed as a child star prodigy covering pop and country songs on many Irish and UK radio and television shows. At age 17, he embarked on a series of music projects like Streetwize, Streetside and Access All Areas, in a bid to be launched as an "international boy band" made up of singers from various nationalities. After the boy band projects fell through, he relaunched a solo music career adopting the name Lee.M, and for a short time formed NXT-GEN, an electropop duo collaboration with Pete Doherty. In 2013, as Lee Matthews, he became part of the country music scene in Ireland in the Country and Irish genre releasing two albums, ''A Little Bitty Country'' in 2014 and ''It's a Great Day to Be Alive'' in 2015 and a string of singles releases. Beginnings as a child star Lee Mulhern was born in Omagh, Northern Ireland. He now lives in the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genome
In the fields of molecular biology and genetics, a genome is all the genetic information of an organism. It consists of nucleotide sequences of DNA (or RNA in RNA viruses). The nuclear genome includes protein-coding genes and non-coding genes, other functional regions of the genome such as regulatory sequences (see non-coding DNA), and often a substantial fraction of 'junk' DNA with no evident function. Almost all eukaryotes have mitochondria and a small mitochondrial genome. Algae and plants also contain chloroplasts with a chloroplast genome. The study of the genome is called genomics. The genomes of many organisms have been sequenced and various regions have been annotated. The International Human Genome Project reported the sequence of the genome for ''Homo sapiens'' in 200The Human Genome Project although the initial "finished" sequence was missing 8% of the genome consisting mostly of repetitive sequences. With advancements in technology that could handle seq ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Princeton University
Princeton University is a private research university in Princeton, New Jersey. Founded in 1746 in Elizabeth as the College of New Jersey, Princeton is the fourth-oldest institution of higher education in the United States and one of the nine colonial colleges chartered before the American Revolution. It is one of the highest-ranked universities in the world. The institution moved to Newark in 1747, and then to the current site nine years later. It officially became a university in 1896 and was subsequently renamed Princeton University. It is a member of the Ivy League. The university is governed by the Trustees of Princeton University and has an endowment of $37.7 billion, the largest endowment per student in the United States. Princeton provides undergraduate and graduate instruction in the humanities, social sciences, natural sciences, and engineering to approximately 8,500 students on its main campus. It offers postgraduate degrees through the Princeton Schoo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Designer Baby
A designer baby is a baby whose genetic makeup has been selected or altered, often to not include a particular gene or to remove genes associated with disease. This process usually involves analysing a wide range of human embryos to identify genes associated with particular diseases and characteristics, and selecting embryos that have the desired genetic makeup; a process known as preimplantation genetic diagnosis. Screening for single genes is commonly practiced, and polygenic screening is offered by a few companies. Other potential methods by which a baby's genetic information can be altered involve directly editing the genome before birth, which is not routinely performed and only one instance of this is known to have occurred as of 2019, where Chinese twins Lulu and Nana were edited as embryos, causing widespread criticism. Genetically altered embryos can be achieved by introducing the desired genetic material into the embryo itself, or into the sperm and/or egg cells of the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Heart Disease
Cardiovascular disease (CVD) is a class of diseases that involve the heart or blood vessels. CVD includes coronary artery diseases (CAD) such as angina and myocardial infarction (commonly known as a heart attack). Other CVDs include stroke, heart failure, hypertensive heart disease, rheumatic heart disease, cardiomyopathy, abnormal heart rhythms, congenital heart disease, valvular heart disease, carditis, aortic aneurysms, peripheral artery disease, thromboembolic disease, and venous thrombosis. The underlying mechanisms vary depending on the disease. It is estimated that dietary risk factors are associated with 53% of CVD deaths. Coronary artery disease, stroke, and peripheral artery disease involve atherosclerosis. This may be caused by high blood pressure, smoking, diabetes mellitus, lack of exercise, obesity, high blood cholesterol, poor diet, excessive alcohol consumption, and poor sleep, among other things. High blood pressure is estimated to account for ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Diabetes
Diabetes, also known as diabetes mellitus, is a group of metabolic disorders characterized by a high blood sugar level (hyperglycemia) over a prolonged period of time. Symptoms often include frequent urination, increased thirst and increased appetite. If left untreated, diabetes can cause many health complications. Acute complications can include diabetic ketoacidosis, hyperosmolar hyperglycemic state, or death. Serious long-term complications include cardiovascular disease, stroke, chronic kidney disease, foot ulcers, damage to the nerves, damage to the eyes, and cognitive impairment. Diabetes is due to either the pancreas not producing enough insulin, or the cells of the body not responding properly to the insulin produced. Insulin is a hormone which is responsible for helping glucose from food get into cells to be used for energy. There are three main types of diabetes mellitus: * Type 1 diabetes results from failure of the pancreas to produce enough insulin due ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
United States
The United States of America (U.S.A. or USA), commonly known as the United States (U.S. or US) or America, is a country primarily located in North America. It consists of 50 U.S. state, states, a Washington, D.C., federal district, five major unincorporated territories, nine United States Minor Outlying Islands, Minor Outlying Islands, and 326 Indian reservations. The United States is also in Compact of Free Association, free association with three Oceania, Pacific Island Sovereign state, sovereign states: the Federated States of Micronesia, the Marshall Islands, and the Palau, Republic of Palau. It is the world's List of countries and dependencies by area, third-largest country by both land and total area. It shares land borders Canada–United States border, with Canada to its north and Mexico–United States border, with Mexico to its south and has maritime borders with the Bahamas, Cuba, Russia, and other nations. With a population of over 333 million, it is the List of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fertility Clinic
Fertility clinics are medical clinics that assist couples, and sometimes individuals, who want to become parents but for medical reasons have been unable to achieve this goal via the natural course. Clinics apply a number of diagnosis tests and sometimes very advanced medical treatments to achieve conceptions and pregnancies. Clinic staff Fertility clinics are staffed with trained personnel including reproductive endocrinologists, embryologists, sonographers, nurses, lab technicians and administrative staff. Additional specialists from acupuncture, hypnotherapy, and nutrition may also be part of the team. You will need one person for each 150 cycles of ICSI (Intra-Cytoplasmic Sperm Injection)/IVF (''In Vitro'' Fertilization). If you are less than that you may have problems, if you have that you do not have problems unless some people are not able to work (pregnancy or diseases) and if you have more than that you are in optimal conditions. Diagnosis Fertility clinics look to bo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sperm Bank
A sperm bank, semen bank, or cryobank is a facility or enterprise which purchases, stores and sells human semen. The semen is produced and sold by men who are known as sperm donors. The sperm is purchased by or for other persons for the purpose of achieving a pregnancy or pregnancies other than by a sexual partner. Sperm sold by a sperm donor is known as donor sperm. A sperm bank may be a separate entity supplying donor sperm to individuals or to fertility centers or clinics, or it may be a facility which is run by a clinic or other medical establishment mainly or exclusively for their patients or customers. A pregnancy may be achieved using donor sperm for insemination with similar outcomes to sexual intercourse. By using sperm from a donor rather than from the sperm recipient's partner, the process is a form of third party reproduction. In the 21st century artificial insemination with donor sperm from a sperm bank is most commonly used for individuals with no male partner, i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nucleic Acid Sequence
A nucleic acid sequence is a succession of Nucleobase, bases signified by a series of a set of five different letters that indicate the order of nucleotides forming alleles within a DNA (using GACT) or RNA (GACU) molecule. By convention, sequences are usually presented from the Directionality (molecular biology), 5' end to the 3' end. For DNA, the Sense (molecular biology), sense strand is used. Because nucleic acids are normally linear (unbranched) polymers, specifying the sequence is equivalent to defining the covalent structure of the entire molecule. For this reason, the nucleic acid sequence is also termed the Biomolecular structure#Primary structure, primary structure. The sequence has capacity to represent information. Biological deoxyribonucleic acid represents the information which directs the functions of an organism. Nucleic acids also have a Nucleic acid secondary structure, secondary structure and Nucleic acid tertiary structure, tertiary structure. Primary structur ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Governmental Organization
A government or state agency, sometimes an appointed commission, is a permanent or semi-permanent organization in the machinery of government that is responsible for the oversight and administration of specific functions, such as an administration. There is a notable variety of agency types. Although usage differs, a government agency is normally distinct both from a department or ministry, and other types of public body established by government. The functions of an agency are normally executive in character since different types of organizations (''such as commissions'') are most often constituted in an advisory role—this distinction is often blurred in practice however, it is not allowed. A government agency may be established by either a national government or a state government within a federal system. Agencies can be established by legislation or by executive powers. The autonomy, independence, and accountability of government agencies also vary widely. History Early exa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sperm Donors
Sperm donation is the provision by a man of his sperm with the intention that it be used in the artificial insemination or other 'fertility treatment' of a woman or women who are not his sexual partners in order that they may become pregnant by him. Where pregnancies go to full term, the sperm donor will be the biological father of every baby born from his donations. The man is known as a sperm donor and the sperm he provides is known as 'donor sperm' because the intention is that the man will give up all legal rights to any child produced from his sperm, and will not be the legal father. Sperm donation may also be known as 'semen donation'. A man provides his semen but the purpose of the donation is that his gametes contained within the semen, i.e. the sperm cells, be used to provide pregnancies for third parties. Sperm donation enables a man to father a child for third-party women and is therefore categorized as a form of third-party reproduction. The process of inseminating ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
