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Gelatin Methacryloyl
Gelatin methacryloyl (GelMA) is a modified form of gelatin that has been chemically functionalized with methacryloyl groups, allowing it to form a stable hydrogel when exposed to UV light and a photoinitiator. This methacrylic anhydride-modified gelatin is used as a base for 3D printing hydrogel bioinks, particularly for applications in tissue engineering, 3D bioprinting, and regenerative medicine. Structure and Composition GelMA is derived from gelatin, a protein obtained by the partial hydrolysis of collagen, which is the primary structural protein in animal connective tissues. The methacryloyl modification allows GelMA to be crosslinked under UV light in the presence of a photoinitiator. This crosslinking gives GelMA its gel-like consistency and stability, while still retaining properties similar to natural extracellular matrices (ECM). Properties Biocompatibility GelMA is highly biocompatible, meaning it supports cell attachment, proliferation, and differentiation. This ma ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gelatin
Gelatin or gelatine () is a translucent, colorless, flavorless food ingredient, commonly derived from collagen taken from animal body parts. It is brittle when dry and rubbery when moist. It may also be referred to as hydrolyzed collagen, collagen hydrolysate, gelatine hydrolysate, hydrolyzed gelatine, and collagen peptides after it has undergone hydrolysis. It is commonly used as a gelling agent in food, beverages, medications, drug or vitamin capsules, photographic films, papers, and cosmetics. Substances containing gelatin or functioning in a similar way are called gelatinous substances. Gelatin is an irreversibly hydrolyzed form of collagen, wherein the hydrolysis reduces protein fibrils into smaller peptides; depending on the physical and chemical methods of denaturation, the molecular weight of the peptides falls within a broad range. Gelatin is present in gelatin desserts, most gummy candy and marshmallows, ice creams, dips, and yogurts. Gelatin for cooking comes ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
