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GRAM Domain
The GRAM domain is found in glucosyltransferases, myotubularins and other membrane-associated proteins. The structure of the GRAM domain is similar to that found in PH domains. Proteins containing GRAM domains are found in all eukaryotes and bacteria, but not archaea. Various GRAM domains can bind proteins or lipids. Human proteins containing this domain GRAMD1A; GRAMD1B; GRAMD1C; GRAMD2A; GRAMD2B; GRAMD4; MTM1; MTMR1; MTMR2; NCOA7; NSMAF; OXR1; SBF1; SBF2; TBC1D8; TBC1D8B; TBC1D9 TBC1 domain family member 9 is a protein that in humans is encoded by the ''TBC1D9'' gene In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation' ...; TBC1D9B; WBP2; WBP2NL; dJ439F8.1; References Protein domains Protein families Peripheral membrane proteins {{membrane-protein-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Glucosyltransferase
Glucosyltransferases are a type of glycosyltransferase that enable the transfer of glucose. Examples include: * glycogen synthase * glycogen phosphorylase Glycogen phosphorylase is one of the phosphorylase enzymes (). Glycogen phosphorylase catalyzes the rate-limiting step in glycogenolysis in animals by releasing glucose-1-phosphate from the terminal alpha-1,4-glycosidic bond. Glycogen phosphor ... They are categorized under EC number 2.4.1. References External links * EC 2.4 {{2.4-enzyme-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
NCOA7
Nuclear receptor coactivator 7 is a protein that in humans is encoded by the ''NCOA7'' gene. See also * Transcription coregulator In molecular biology and genetics, transcription coregulators are proteins that interact with transcription factors to either activate or repress the transcription of specific genes. Transcription coregulators that activate gene transcription ar ... References External links * Further reading * * * * * * * * * * * * * * External links * Gene expression Transcription coregulators Human proteins {{gene-6-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein Domains
In molecular biology, a protein domain is a region of a protein's polypeptide chain that is self-stabilizing and that folds independently from the rest. Each domain forms a compact folded three-dimensional structure. Many proteins consist of several domains, and a domain may appear in a variety of different proteins. Molecular evolution uses domains as building blocks and these may be recombined in different arrangements to create proteins with different functions. In general, domains vary in length from between about 50 amino acids up to 250 amino acids in length. The shortest domains, such as zinc fingers, are stabilized by metal ions or disulfide bridges. Domains often form functional units, such as the calcium-binding EF hand domain of calmodulin. Because they are independently stable, domains can be "swapped" by genetic engineering between one protein and another to make chimeric proteins. Background The concept of the domain was first proposed in 1973 by Wetlaufer aft ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
WBP2NL
WBP may refer to: *West Bengal Police, one of the two police forces of the Indian state of West Bengal *West Brompton station, London, National Rail station code *Western Block Party, a defunct Canadian federal political party *White Boy Posse White Boy Posse (WBP), a.k.a. Whiteboy Posse, are a Canadian white supremacist neo-Nazi organized crime group founded in 2003 in Edmonton, Alberta, Canada, the organization is primarily active in Western Canada. Formation and history The White B ..., a Canadian white supremacist neo-Nazi organized crime group * Weather and Boil Proof (WBP) glue, glue used for marine plywood fabrication {{disambiguation ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
WBP2
WW domain-binding protein 2 is a protein that in humans is encoded by the ''WBP2'' gene. The globular WW domain is composed of 38 to 40 semiconserved amino acids shared by proteins of diverse functions including structural, regulatory, and signaling proteins. The domain is involved in mediating protein-protein interactions through the binding of polyproline ligands. This gene encodes a WW domain binding protein, which binds to the WW domain of Yes kinase-associated protein by its PY motifs. The function of this protein has not been determined. Model organisms Model organisms have been used in the study of WBP2 function. A conditional knockout mouse line, called ''Wbp2tm1a(EUCOMM)Wtsi'' was generated as part of the International Knockout Mouse Consortium program — a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists. Male and female animals underwent a standardized phenotypic screen to determine the effects of deleti ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
TBC1D9
TBC1 domain family member 9 is a protein that in humans is encoded by the ''TBC1D9'' gene In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a b .... References Further reading * * * * * * * * {{gene-4-stub EF-hand-containing proteins ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
SBF2
Myotubularin-related protein 13 is a protein that in humans is encoded by the ''SBF2'' gene. The family of myotubularin-related proteins includes lipid phosphatases, such as MTM1 (MIM 600415), and pseudophosphatases, such as SBF1 (MIM 603560) and SBF2. Pseudophosphatases contain inactivating substitutions at the catalytic cysteine Cysteine (symbol Cys or C; ) is a semiessential proteinogenic amino acid with the formula . The thiol side chain in cysteine often participates in enzymatic reactions as a nucleophile. When present as a deprotonated catalytic residue, s ... upplied by OMIM References Further reading * * * * * * * * * * * External links GeneReviews/NCBI/NIH/UW entry on Charcot-Marie-Tooth Neuropathy Type 4 {{gene-11-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
SBF1
Myotubularin-related protein 5 is a protein that in humans is encoded by the ''SBF1'' gene. Interactions SBF1 has been shown to interact with MTMR2 and SUV39H1 Histone-lysine N-methyltransferase SUV39H1 is an enzyme that in humans is encoded by the ''SUV39H1'' gene. Function This gene is a member of the suppressor of variegation 3-9 homolog family and encodes a protein with a chromodomain and a C-ter .... References Further reading * * * * * External links * {{gene-22-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
