Fucosidase

	Fucosidase Fucosidase is an enzyme, fucohydrolase, a type of glycoside hydrolase. Fucosidase may refer to: * Alpha-L-fucosidase, α-L-fucosidase () Tissue alpha-L-fucosidase, Tissue alpha-L-fucosidase, encoded by ''FUCA1'' gene Plasma alpha-L-fucosidase, encoded by ''FUCA2'' gene * 1,2-α-L-fucosidase, 1,2-α-L-fucosidase () * 1,3-alpha-L-fucosidase, 1,3-α-L-fucosidase () * 1,6-alpha-L-fucosidase, 1,6-α-L-fucosidase () * β-D-Fucosidase, β-D-Fucosidase () See also * Enzyme Commission number, EC number * Fucose {{Sugar hydrolases ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Tissue Alpha-L-fucosidase Tissue alpha-L-fucosidase is an enzyme that in humans is encoded by the ''FUCA1'' gene. Alpha-fucosidase is an enzyme that breaks out fucose.HPRD entr Fucosidosis is an autosomal recessive lysosomal storage disease caused by defective alpha-L-fucosidase with accumulation of fucose in the tissues. Different phenotypes include clinical features such as neurologic deterioration, growth retardation, visceromegaly, and seizures in a severe early form; coarse facial features, angiokeratoma corporis diffusum, spasticity and delayed psychomotor development in a longer surviving form; and an unusual spondylometaphyseoepiphyseal dysplasia in yet another form.[supplied by OMIM] See also * FUCA2 * Fucosidosis References Further reading * * * * * * * * * * * * * * * * * * External links * Enzymes {{hydrolase-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	FUCA2 Plasma alpha-L-fucosidase (see alpha-L-fucosidase) is an enzyme that in humans is encoded by the ''FUCA2'' gene. See also * Tissue alpha-L-fucosidase Tissue alpha-L-fucosidase is an enzyme that in humans is encoded by the ''FUCA1'' gene. Alpha-fucosidase is an enzyme that breaks out fucose.HPRD entr Fucosidosis is an autosomal recessive lysosomal storage disease caused by defective alpha-L-fu ..., encoded by ''FUCA1'' gene References Further reading * * * * * * * * {{gene-6-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	1,2-α-L-fucosidase The enzyme 1,2-α-L-fucosidase () catalyzes the following chemical reaction: :methyl-2-α-L-fucopyranosyl-β-D-galactoside + HO \rightleftharpoons L-fucose + methyl β-D-galactoside It belongs to the family of hydrolases, specifically those glycosidases that hydrolyse ''O''- and ''S''-glycosyl compounds. The systematic name is 2-α-L-fucopyranosyl-β-D-galactoside fucohydrolase. Other names in common use include almond emulsin fucosidase, and α-(1→2)-L-fucosidase. Structural studies As of late 2007, 4 structures A structure is an arrangement and organization of interrelated elements in a material object or system, or the object or system so organized. Material structures include man-made objects such as buildings and machines and natural objects such as ... have been solved for this class of enzymes, with PDB accession codes , , , and . References * * * EC 3.2.1 Enzymes of known structure {{3.2-enzyme-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	1,3-alpha-L-fucosidase The enzyme 1,3-α-L-fucosidase () catalyzes the hydrolytic cleavage of the 1,3-linkages between α-L-fucose and ''N''-acetylglucosamine residues in glycoproteins. It belongs to the family of hydrolases, specifically those glycosidases that hydrolyse ''O''- and ''S''-glycosyl compounds. The systematic name of this enzyme class is 3-α-L-fucosyl-''N''-acetylglucosaminyl-glycoprotein fucohydrolase. This enzyme is also called almond emulsin fucosidase I. It participates in the degradation of glycan The terms glycans and polysaccharides are defined by IUPAC as synonyms meaning "compounds consisting of a large number of monosaccharides linked glycosidically". However, in practice the term glycan may also be used to refer to the carbohydrate ... structures. References * * * EC 3.2.1 Enzymes of unknown structure {{3.2-enzyme-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	1,6-alpha-L-fucosidase The enzyme 1,6-α-L-fucosidase () catalyses the following chemical reaction :Hydrolysis of 1,6-linkages between α-L-fucose and ''N''-acetyl-D-glucosamine in glycopeptides such as immunoglobulin G glycopeptide and fucosyl-asialo-agalacto-fetuin It belongs to the family of hydrolases, specifically those glycosidases that hydrolyse ''O''- and ''S''-glycosyl compounds. The systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature. A semisystematic name or semitrivi ... is 1,6-L-fucosyl-''N''-acetyl-D-glucosaminylglycopeptide fucohydrolase. It is also called α-L-fucosidase. References * EC 3.2.1 Enzymes of unknown structure {{3.2-enzyme-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	β-D-Fucosidase β-D-Fucosidase (, ''β-fucosidase'') is an enzyme with systematic name ''β-D-fucoside fucohydrolase''. This enzyme catalyses the following chemical reaction : Hydrolysis of terminal non-reducing β-D-fucose residues in β-D-fucosides Enzymes from some sources also hydrolyse β-D-galactosides, β-D-glucoside A glucoside is a glycoside that is chemically derived from glucose. Glucosides are common in plants, but rare in animals. Glucose is produced when a glucoside is hydrolysed by purely chemical means, or decomposed by fermentation or enzymes. Th ...s and α-L- arabinosides. References External links * {{Portal bar, Biology, border=no EC 3.2.1 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Glycoside Hydrolase In biochemistry, glycoside hydrolases (also called glycosidases or glycosyl hydrolases) are a class of enzymes which catalysis, catalyze the hydrolysis of glycosidic bonds in polysaccharide, complex sugars. They are extremely common enzymes, with roles in nature including degradation of biomass such as cellulose (cellulase), hemicellulose, and starch (amylase), in anti-bacterial defense strategies (e.g., lysozyme), in pathogenesis mechanisms (e.g., viral neuraminidases) and in normal cellular function (e.g., trimming alpha-Mannosidase, mannosidases involved in N-linked glycoprotein, ''N''-linked glycoprotein biosynthesis). Together with glycosyltransferases, glycosidases form the major catalytic machinery for the synthesis and breakage of glycosidic bonds. Occurrence and importance Glycoside hydrolases are found in essentially all domains of life. In prokaryotes, they are found both as intracellular and extracellular enzymes that are largely involved in nutrient acquisitio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Enzyme Commission Number The Enzyme Commission number (EC number) is a numerical classification scheme for enzymes, based on the chemical reactions they catalyze. As a system of enzyme nomenclature, every EC number is associated with a recommended name for the corresponding enzyme-catalyzed reaction. EC numbers do not specify enzymes but enzyme-catalyzed reactions. If different enzymes (for instance from different organisms) catalyze the same reaction, then they receive the same EC number. Furthermore, through convergent evolution, completely different protein folds can catalyze an identical reaction (these are sometimes called non-homologous isofunctional enzymes) and therefore would be assigned the same EC number. By contrast, UniProt identifiers uniquely specify a protein by its amino acid sequence. Format of number Every enzyme code consists of the letters "EC" followed by four numbers separated by periods. Those numbers represent a progressively finer classification of the enzyme. Preliminary ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]