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Frank E. Speizer
Frank Erwin Speizer (born 8 June 1935) is an American physician and epidemiologist, currently Professor of Environmental Health and Environmental Science at Harvard T.H. Chan School of Public Health, and Edward H. Kass Distinguished Professor of Medicine at Brigham and Women's Hospital, Harvard Medical School. He is best known for his work on two major epidemiological cohort studies: the Nurses' Health Study, which explored women's illnesses and health risk factors, and the Harvard Six Cities study, which definitively linked air pollution to higher death rates in urban areas. Early life and career Speizer was born in San Francisco and studied for a bachelor's degree (1957) and MD (1960) at Stanford University and Stanford Medical School, completing his medical training at Boston City Hospital and Stanford-Palo Alto Hospital. After discovering a keen interest in mathematics, he began working in epidemiology, specializing in air pollution, initially as a summer student at the C ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
San Francisco
San Francisco, officially the City and County of San Francisco, is a commercial, Financial District, San Francisco, financial, and Culture of San Francisco, cultural center of Northern California. With a population of 827,526 residents as of 2024, San Francisco is the List of California cities by population, fourth-most populous city in the U.S. state of California and the List of United States cities by population, 17th-most populous in the United States. San Francisco has a land area of at the upper end of the San Francisco Peninsula and is the County statistics of the United States, fifth-most densely populated U.S. county. Among U.S. cities proper with over 250,000 residents, San Francisco is ranked first by per capita income and sixth by aggregate income as of 2023. San Francisco anchors the Metropolitan statistical area#United States, 13th-most populous metropolitan statistical area in the U.S., with almost 4.6 million residents in 2023. The larger San Francisco Bay Area ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stanford Medical School
The Stanford University School of Medicine is the medical school of Stanford University and is located in Stanford, California, United States. It traces its roots to the Medical Department of the University of the Pacific, founded in San Francisco in 1858. This medical institution, then called Cooper Medical College, was acquired by Stanford in 1908. In 1959, the medical school moved to the Stanford campus near Palo Alto, California. The School of Medicine, along with Stanford Health Care and Lucile Packard Children's Hospital, is part of Stanford Medicine. History In 1855, Illinois physician Elias Samuel Cooper moved to San Francisco in the wake of the California Gold Rush. In cooperation with the University of the Pacific (also known as California Wesleyan College), Cooper established the Medical Department of the University of the Pacific, the first medical school on the West Coast, in 1858, on Mission Street near 3rd Street in San Francisco. However, Cooper died in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Semantic Scholar
Semantic Scholar is a research tool for scientific literature. It is developed at the Allen Institute for AI and was publicly released in November 2015. Semantic Scholar uses modern techniques in natural language processing to support the research process, for example by providing automatically generated summaries of scholarly papers. The Semantic Scholar team is actively researching the use of artificial intelligence in natural language processing, machine learning, human–computer interaction, and information retrieval. Semantic Scholar began as a database for the topics of computer science, geoscience, and neuroscience. In 2017, the system began including biomedical literature in its corpus. , it includes over 200 million publications from all fields of science. Technology Semantic Scholar provides a one-sentence summary of scientific literature. One of its aims was to address the challenge of reading numerous titles and lengthy abstracts on mobile devices. It also seeks t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Douglas Dockery
Douglas William Dockery is an American epidemiologist and the John L. Loeb and Frances Lehman Loeb Professor of Environmental Epidemiology, Emeritus, at the Harvard School of Public Health (HSPH). He is known for his contributions to understanding the health effects of air pollution. Education Dockery received his B.S. in physics from the University of Maryland and his M.S. in meteorology from the Massachusetts Institute of Technology in 1972, where he studied under biometeorologist Helmut Landsberg. He further pursued meteorology at the Massachusetts Institute of Technology (MIT) under the guidance of Edward Lorenz, completing a master's thesis on the predictability of atmospheric models in 1972. Dockery continued his education at the Harvard School of Public Health, obtaining both a Master of Science (M.S.) and a Doctor of Science (Sc.D.) in Environmental Science. His doctoral research, supervised by John Spengler, focused on personal exposures to fine particulate matter. Ca ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Heart Disease
Cardiovascular disease (CVD) is any disease involving the heart or blood vessels. CVDs constitute a class of diseases that includes: coronary artery diseases (e.g. angina pectoris, angina, myocardial infarction, heart attack), heart failure, hypertensive heart disease, rheumatic heart disease, cardiomyopathy, arrhythmia, congenital heart disease, valvular heart disease, carditis, aortic aneurysms, peripheral artery disease, Thrombosis, thromboembolic disease, and venous thrombosis. The underlying mechanisms vary depending on the disease. It is estimated that dietary risk factors are associated with 53% of CVD deaths. Coronary artery disease, stroke, and peripheral artery disease involve atherosclerosis. This may be caused by hypertension, high blood pressure, tobacco smoking, smoking, diabetes mellitus, lack of physical exercise, exercise, obesity, hypercholesterolaemia, high blood cholesterol, poor diet, excessive alcoholic beverage, alcohol consumption, and poor sleep, amo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cancer
Cancer is a group of diseases involving Cell growth#Disorders, abnormal cell growth with the potential to Invasion (cancer), invade or Metastasis, spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible Signs and symptoms of cancer, signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in defecation, bowel movements. While these symptoms may indicate cancer, they can also have other causes. List of cancer types, Over 100 types of cancers affect humans. Tobacco use is the cause of about 22% of cancer deaths. Another 10% are due to obesity, poor Diet (nutrition), diet, sedentary lifestyle, lack of physical activity or Alcohol abuse, excessive alcohol consumption. Other factors include certain infections, exposure to ionizing radiation, and environmental pollutants. infectious causes of cancer, Infection with specific viruses, bacteria and parasites is an environmental factor cau ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Particulates
Particulate matter (PM) or particulates are microscopic particles of solid or liquid matter suspension (chemistry), suspended in the atmosphere of Earth, air. An ''aerosol'' is a mixture of particulates and air, as opposed to the particulate matter alone, though it is sometimes defined as a subset of aerosol terminology. Sources of particulate matter can be natural or anthropogenic hazard, anthropogenic. Particulates have impacts on climate and precipitation that adversely affect human health. Types of atmosphere, atmospheric particles include suspended particulate matter; thoracic and respirable particles; inhalable coarse particles, designated PM, which are granularity, coarse particles with a particle size, diameter of 10 micrometre, micrometers (μm) or less; fine particles, designated PM, with a diameter of 2.5 μm or less; ultrafine particles, with a diameter of 100 nm or less; and soot. Airborne particulate matter is a List of IARC Group 1 carcinogens, Group ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Correlation
In statistics, correlation or dependence is any statistical relationship, whether causal or not, between two random variables or bivariate data. Although in the broadest sense, "correlation" may indicate any type of association, in statistics it usually refers to the degree to which a pair of variables are '' linearly'' related. Familiar examples of dependent phenomena include the correlation between the height of parents and their offspring, and the correlation between the price of a good and the quantity the consumers are willing to purchase, as it is depicted in the demand curve. Correlations are useful because they can indicate a predictive relationship that can be exploited in practice. For example, an electrical utility may produce less power on a mild day based on the correlation between electricity demand and weather. In this example, there is a causal relationship, because extreme weather causes people to use more electricity for heating or cooling. However, in g ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oral Contraceptives
Oral contraceptives, abbreviated OCPs, also known as birth control pills, are medications taken by mouth for the purpose of birth control. The introduction of the birth control pill ("the Pill") in 1960 revolutionized the options for contraception, sparking vibrant discussion in the scientific and social science literature and in the media. Much attention focused on issues of women's rights, including ethics and personal choice. But these medications also introduced new questions about risk. Female Two types of female oral contraceptive pill, taken once per day, are widely available: * The combined oral contraceptive pill contains estrogen and a progestin; colloquially known as "the Pill". * The progestogen-only pill, colloquially known as "minipill". For perfect use it is 99% effective and typical use is 91% effective. Side effects of the pill include headache, dizziness, nausea, sore breasts, spotting, mood changes, acne, bloating, etc. One pill offers the benefit of only havin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cohort Study
A cohort study is a particular form of longitudinal study that samples a Cohort (statistics), cohort (a group of people who share a defining characteristic, typically those who experienced a common event in a selected period, such as birth or graduation), performing a Cross-sectional data, cross-section at intervals through time. It is a type of panel study where the individuals in the panel share a common characteristic. Cohort studies represent one of the fundamental designs of epidemiology which are used in research in the fields of medicine, pharmacy, nursing, Psychological research, psychology, social science, and in any field reliant on 'difficult to reach' answers that are based on evidence (statistics). In medicine for instance, while clinical trials are used primarily for assessing the safety of newly developed pharmaceuticals before they are approved for sale, epidemiological analysis on how risk factors affect the incidence of diseases is often used to identify the caus ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Richard Doll
Sir William Richard Shaboe Doll (28 October 1912 – 24 July 2005) was a British physician who became an epidemiologist in the mid-20th century and made important contributions to that discipline. He was a pioneer in research linking smoking to health problems. With Ernst Wynder, Bradford Hill and Evarts Graham, he was credited with being the first to prove that smoking increased the risk of :lung cancer and :heart disease. (German studies had suggested a link as early as the 1920s but were forgotten or ignored until the 1990s.) He also carried out pioneering work on the relationship between radiation and leukaemia as well as that between asbestos and lung cancer, and alcohol and breast cancer. He however, initially for many years, stood in opposition to research done by Alice Stewart which connected radiation exposure of pregnant mothers to development of leukaemia in their children due to her 'questionable' analysis. On 28 June 2012, he was the subject of an episode of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Asthma
Asthma is a common long-term inflammatory disease of the airways of the lungs. It is characterized by variable and recurring symptoms, reversible airflow obstruction, and easily triggered bronchospasms. Symptoms include episodes of wheezing, coughing, chest tightness, and shortness of breath. A sudden worsening of asthma symptoms sometimes called an 'asthma attack' or an 'asthma exacerbation' can occur when allergens, pollen, dust, or other particles, are inhaled into the lungs, causing the bronchioles to constrict and produce mucus, which then restricts oxygen flow to the alveoli. These may occur a few times a day or a few times per week. Depending on the person, asthma symptoms may become worse at night or with exercise. Asthma is thought to be caused by a combination of genetic and environmental factors. Environmental factors include exposure to air pollution and allergens. Other potential triggers include medications such as aspirin and beta blockers. Diag ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
