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Francis Brambell
Francis William Rogers Brambell (25 February 1901 – 6 June 1970) was an Irish medical scientist who spent all of his professional working life in Britain. Education Brambell was born in Sandycove, Dublin and was educated (1911–1914) at Aravon School and then privately, specializing in zoology. He entered Trinity College Dublin with an Entrance Prize in natural science. In 1920 Brambell won a Foundation Scholarship and in 1922 he graduated B.A. with Senior Moderatorship and gold medal in natural sciences, and was awarded a postgraduate Fellowship prize. During his first degree he was taught by some distinguished scientists including Professors Henry Horatio Dixon FRS, John Joly FRS, and James Brontë Gatenby. After graduation he worked in cytology under Professor James Brontë Gatenby, gained his BSc (subsequently transformed into MSc) in 1923, and his PhD in 1924 (this was the first PhD of Trinity College Dublin). In 1924 he was awarded a Science Research Scholarship f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dublin
Dublin is the capital and largest city of Republic of Ireland, Ireland. Situated on Dublin Bay at the mouth of the River Liffey, it is in the Provinces of Ireland, province of Leinster, and is bordered on the south by the Dublin Mountains, part of the Wicklow Mountains range. Dublin is the largest city by population on the island of Ireland; at the 2022 census of Ireland, 2022 census, the city council area had a population of 592,713, while the city including suburbs had a population of 1,263,219, County Dublin had a population of 1,501,500. Various definitions of a metropolitan Greater Dublin Area exist. A settlement was established in the area by the Gaels during or before the 7th century, followed by the Vikings. As the Kingdom of Dublin grew, it became Ireland's principal settlement by the 12th century Anglo-Norman invasion of Ireland. The city expanded rapidly from the 17th century and was briefly the second largest in the British Empire and sixth largest in Western Europ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Immunity (medical)
In biology, immunity is the state of being insusceptible or resistant to a noxious agent or process, especially a pathogen or infectious disease. Immunity may occur naturally or be produced by prior exposure or immunization. Innate and adaptive The immune system has Innate immune system, innate and Adaptive immune system, adaptive components. Innate immunity is present in all metazoans, immune responses: inflammation, inflammatory responses and phagocytosis. The adaptive component, on the other hand, involves more advanced lymphocyte, lymphatic cells that can distinguish between specific "non-self" substances in the presence of "self". The reaction to foreign substances is etymologically described as inflammation while the non-reaction to self substances is described as immunity. The two components of the immune system create a dynamic biological environment where "health" can be seen as a physical state where the self is immunologically spared, and what is foreign is inflammat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fellows Of The Royal Society
Fellowship of the Royal Society (FRS, ForMemRS and HonFRS) is an award granted by the Fellows of the Royal Society of London to individuals who have made a "substantial contribution to the improvement of natural science, natural knowledge, including mathematics, engineering science, and medical science". Overview Fellowship of the Society, the oldest known scientific academy in continuous existence, is a significant honour. It has been awarded to :Fellows of the Royal Society, around 8,000 fellows, including eminent scientists Isaac Newton (1672), Benjamin Franklin (1756), Charles Babbage (1816), Michael Faraday (1824), Charles Darwin (1839), Ernest Rutherford (1903), Srinivasa Ramanujan (1918), Jagadish Chandra Bose (1920), Albert Einstein (1921), Paul Dirac (1930), Subrahmanyan Chandrasekhar (1944), Prasanta Chandra Mahalanobis (1945), Dorothy Hodgkin (1947), Alan Turing (1951), Lise Meitner (1955), Satyendra Nath Bose (1958), and Francis Crick (1959). More recently, fellow ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alumni Of Trinity College Dublin
Alumni (: alumnus () or alumna ()) are former students or graduates of a school, college, or university. The feminine plural alumnae is sometimes used for groups of women, and alums (: alum) or alumns (: alumn) as gender-neutral alternatives. The word comes from Latin, meaning nurslings, pupils or foster children, derived from "to nourish". The term is not synonymous with "graduates": people can be alumni without graduating, e.g. Burt Reynolds was an alumnus of Florida State University but did not graduate. The term is sometimes used to refer to former employees, former members of an organization, former contributors, or former inmates. Etymology The Latin noun means "foster son" or "pupil". It is derived from the Latin verb "to nourish". Separate, but from the same root, is the adjective "nourishing", found in the phrase '' alma mater'', a title for a person's home university. Usage in Roman law In Latin, is a legal term (Roman law) to describe a child placed in foste ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1970 Deaths
Events January * January 1 – Unix time epoch reached at 00:00:00 UTC. * January 5 – The 7.1 1970 Tonghai earthquake, Tonghai earthquake shakes Tonghai County, Yunnan province, China, with a maximum Mercalli intensity scale, Mercalli intensity of X (''Extreme''). Between 10,000 and 14,621 are killed and 30,000 injured. * January 15 – After a 32-month fight for independence from Nigeria, Biafran forces under Philip Effiong formally surrender to General Yakubu Gowon, ending the Nigerian Civil War. February * February 1 – The Benavídez rail disaster near Buenos Aires, Argentina (a rear-end collision) kills 236. * February 10 – An avalanche at Val-d'Isère, France, kills 41 tourists. * February 11 – ''Ohsumi (satellite), Ohsumi'', Japan's first satellite, is launched on a Lambda-4 rocket. * February 22 – Guyana becomes a Republic within the Commonwealth of Nations. * February – Multi-business Conglomerate (company), conglomerate Virgin Group is founded as a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1901 Births
December 13 of this year is the beginning of signed 32-bit computing, 32-bit Unix time, and is scheduled to end in Year 2038 problem, January 19, 2038. Summary Political and military 1901 started with the Federation of Australia, unification of multiple Crown colony, British colonies in Australia on January 1 to form the Australia, Commonwealth of Australia after a 1898–1900 Australian constitutional referendums, referendum in 1900, Subsequently, the 1901 Australian federal election, 1901 Australian election would see the first Prime Minister of Australia, Australian prime minister, Edmund Barton. On the same day, Nigeria became a Colonial Nigeria, British protectorate. Following this, the Victorian era, Victorian Era would come to a end after Queen Victoria died on January 22 after a reign of 63 years and 216 days, which was List of monarchs in Britain by length of reign, longer than those of any of her predecessors, Her son, Edward VII, succeeded her to the throne. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Five Freedoms
The Five Freedoms, sometimes referred to as the Five Freedoms model, is a framework for assessing animal welfare that uses an outline of five aspects. They were developed in response to a 1965 UK Government report on livestock husbandry, and were formalised in a 1979 press statement by the UK Farm Animal Welfare Council. They have been adopted by the European Union and in some other countries and endorsed by some professional groups including the Federation of Veterinarians of Europe, and organisations including the World Organisation for Animal Health, the Royal Society for the Prevention of Cruelty to Animals, and the American Society for the Prevention of Cruelty to Animals. Current compact The five freedoms as expressed by the Farm Animal Welfare Council in 2009 are: # Freedom from hunger or thirst by ready access to fresh water and a diet to maintain full health and vigour # Freedom from discomfort by providing an appropriate environment including shelter and a comfortable ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Catabolism
Catabolism () is the set of metabolic pathways that breaks down molecules into smaller units that are either oxidized to release energy or used in other anabolic reactions. Catabolism breaks down large molecules (such as polysaccharides, lipids, nucleic acids, and proteins) into smaller units (such as monosaccharides, fatty acids, nucleotides, and amino acids, respectively). Catabolism is the breaking-down aspect of metabolism, whereas anabolism is the building-up aspect. Cells use the monomers released from breaking down polymers to either construct new polymer molecules or degrade the monomers further to simple waste products, releasing energy. Cellular wastes include lactic acid, acetic acid, carbon dioxide, ammonia, and urea. The formation of these wastes is usually an oxidation process involving a release of chemical free energy, some of which is lost as heat, but the rest of which is used to drive the synthesis of adenosine triphosphate (ATP). This molecule acts as a way ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Passive Immunity
In immunology, passive immunity is the transfer of active humoral immunity of ready-made antibodies. Passive immunity can occur naturally, when maternal antibodies are transferred to the fetus through the placenta, and it can also be induced artificially, when high levels of antibodies specific to a pathogen or toxin (obtained from humans, horses, or other animals) are transferred to non- immune persons through blood products that contain antibodies, such as in immunoglobulin therapy or antiserum therapy. Passive immunization is used when there is a high risk of infection and insufficient time for the body to develop its own immune response, or to reduce the symptoms of ongoing or immunosuppressive diseases. Passive immunization can be provided when people cannot synthesize antibodies, and when they have been exposed to a disease that they do not have immunity against. Naturally acquired Maternal passive immunity Maternal passive immunity is a type of naturally acquired passiv ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Immunoglobulin G
Immunoglobulin G (IgG) is a type of antibody. Representing approximately 75% of serum antibodies in humans, IgG is the most common type of antibody found in blood circulation. IgG molecules are created and released by plasma B cells. Each IgG antibody has two paratopes. Function Antibodies are major components of humoral immunity. IgG is the main type of antibody found in blood and extracellular fluid, allowing it to control infection of body tissues. By binding many kinds of pathogens such as viruses, bacteria, and fungi, IgG protects the body from infection. It does this through several mechanisms: * IgG-mediated binding of pathogens causes their immobilization and binding together via agglutination; IgG coating of pathogen surfaces (known as opsonization) allows their recognition and ingestion by phagocytic immune cells leading to the elimination of the pathogen itself; * IgG activates the classical pathway of the complement system, a cascade of immune protein product ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fc Receptor
In immunology, an Fc receptor is a protein found on the surface of certain cells – including, among others, B lymphocytes, follicular dendritic cells, natural killer cells, macrophages, neutrophils, eosinophils, basophils, human platelets, and mast cells – that contribute to the protective functions of the immune system. Its name is derived from its binding specificity for a part of an antibody known as the Fc (fragment crystallizable) region. Fc receptors bind to antibodies that are attached to infected cells or invading pathogens. Their activity stimulates phagocytic or cytotoxic cells to destroy microbes, or infected cells by antibody-mediated phagocytosis or antibody-dependent cell-mediated cytotoxicity. Some viruses such as flaviviruses use Fc receptors to help them infect cells, by a mechanism known as antibody-dependent enhancement of infection. Classes There are several different types of Fc receptors (abbreviated FcR), which are classified based on th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
John Joly
John Joly (; 1 November 1857 – 8 December 1933) was an Irish geologist and physicist known for his development of radiotherapy in the treatment of cancer. He is also known for developing techniques to more accurately estimate the age of a geological period, based on radioactive elements present in minerals, the uranium–thorium dating.Obituary, Irish Times, 16 December 1933, page 1 Early life Joly was born in Holywood House (the Church of Ireland Rectory), Bracknagh, Kings's County, Ireland. He was a second cousin of astronomer Charles Jasper Joly. He entered Trinity College, Dublin in 1876, graduating in Engineering in 1882 in first place with several special certificates in branches of engineering, at the same time obtaining a First Class Honours in modern literature. He worked as a demonstrator in Trinity's Engineering and Physics departments before succeeding William Johnson Sollas in the Chair of Geology and Mineralogy in 1897, a position which he held until his dea ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
