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Facial Paralysis
Facial nerve paralysis is a common problem that involves the paralysis of any structures innervated by the facial nerve. The pathway of the facial nerve is long and relatively convoluted, so there are a number of causes that may result in facial nerve paralysis. The most common is Bell's palsy, a disease of unknown cause that may only be diagnosed by exclusion of identifiable serious causes. Signs and symptoms Facial nerve paralysis is characterised by facial weakness, usually only on one side of the face, with other symptoms possibly including loss of taste, hyperacusis and decreased salivation and tear secretion. Other signs may be linked to the cause of the paralysis, such as vesicles in the ear, which may occur if the facial palsy is due to shingles. Symptoms may develop over several hours. Acute facial pain radiating from the ear may precede the onset of other symptoms. Causes Bell's palsy Bell's palsy is the most common cause of acute facial nerve paralysis. There is ...
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Moche Culture
The Moche civilization (; alternatively, the Moche culture or the Early, Pre- or Proto-Chimú culture, Chimú) flourished in northern Peru with its capital near present-day Moche, Trujillo, Peru from about 100 to 800 AD during the Cultural periods of Peru, Regional Development Epoch. While this issue is the subject of some debate, many scholars contend that the Moche were not politically organized as a monolithic empire or state. Rather, they were likely a group of autonomous polities that shared a common culture, as seen in the rich iconography and monumental architecture that survives today. Background Moche society was agriculturally based, with a significant level of investment in the construction of a sophisticated network of irrigation canals for the diversion of river water to supply their crops. Their artifacts express their lives, with detailed scenes of hunting, fishing, fighting, sacrifice, sexual encounters, and elaborate ceremonies. The Moche are particularly note ...
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Borrelia Burgdorferi
''Borrelia burgdorferi'' is a bacterial species of the spirochete class in the genus '' Borrelia'', and is one of the causative agents of Lyme disease in humans. Along with a few similar genospecies, some of which also cause Lyme disease, it makes up the species complex of ''Borrelia burgdorferi'' sensu lato. The complex currently comprises 20 accepted and 3 proposed genospecies. ''B. burgdorferi'' sensu stricto exists in North America and Eurasia and until 2016 was the only known cause of Lyme disease in North America. ''B. burgdorferi'' are often mistakenly described as Gram negative because of their two external membranes, but they lack lipopolysaccharide and possess many surface lipoproteins, unlike true Gram-negative bacteria. Microbiology ''Borrelia burgdorferi'' is named after the researcher Willy Burgdorfer, who first isolated the bacterium in 1982. ''Borrelia burgdorferi'' is a microaerophile, requiring small amounts of oxygen in order to undergo glycolysis and s ...
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Steroid
A steroid is an organic compound with four fused compound, fused rings (designated A, B, C, and D) arranged in a specific molecular configuration. Steroids have two principal biological functions: as important components of cell membranes that alter membrane fluidity; and as signal transduction, signaling molecules. Examples include the lipid cholesterol, sex hormones estradiol and testosterone, anabolic steroids, and the anti-inflammatory corticosteroid drug dexamethasone. Hundreds of steroids are found in Fungus, fungi, plants, and animals. All steroids are manufactured in cells from a sterols, sterol: Cholesterol, cholesterol (animals), lanosterol (opisthokonts), or cycloartenol (plants). All three of these molecules are produced via Cyclic compound, cyclization of the triterpene squalene. Structure The steroid nucleus (parent structure, core structure) is called gonane (cyclopentanoperhydrophenanthrene). It is typically composed of seventeen carbon atoms, bonded in fou ...
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Antiviral Drug
Antiviral drugs are a class of medication used for treating viral infections. Most antivirals target specific viruses, while a broad-spectrum antiviral is effective against a wide range of viruses. Antiviral drugs are a class of antimicrobials, a larger group which also includes antibiotic (also termed antibacterial), antifungal and antiparasitic drugs, or antiviral drugs based on monoclonal antibodies. Most antivirals are considered relatively harmless to the host, and therefore can be used to pharmacotherapy, treat infections. They should be distinguished from virucides, which are not medication but deactivate or destroy virus particles, either inside or outside the body. Natural virucides are produced by some plants such as eucalyptus and Australian tea trees. Medical uses Most of the antiviral drugs now available are designed to help deal with HIV, Herpesviridae, herpes viruses, the hepatitis B and Hepatitis C, C viruses, and Influenzavirus A, influenza A and Influenzavirus ...
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Dizziness
Dizziness is an imprecise term that can refer to a sense of disorientation in space, vertigo, or lightheadedness. It can also refer to Balance disorder, disequilibrium or a non-specific feeling, such as giddiness or foolishness. Dizziness is a common medical complaint, affecting 20–30% of persons. Dizziness is broken down into four main subtypes: vertigo (~25–50%), equilibrioception#Dysfunction, disequilibrium (less than ~15%), presyncope (less than ~15%), and nonspecific dizziness (~10%). * Vertigo is the sensation of spinning or having one's surroundings spin about them. Many people find vertigo very disturbing and often report associated nausea and vomiting. * Presyncope describes lightheadedness or feeling faint; the name relates to Syncope (medicine), syncope, which is actually fainting. * equilibrioception#Dysfunction, Disequilibrium is the sensation of being off balance and is most often characterized by frequent falls in a specific direction. This condition is not of ...
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Sensorineural Hearing Loss
Sensorineural hearing loss (SNHL) is a type of hearing loss in which the root cause lies in the inner ear, sensory organ (cochlea and associated structures), or the vestibulocochlear nerve (Cranial nerves, cranial nerve VIII). SNHL accounts for about 90% of reported hearing loss. SNHL is usually permanent and can be mild, moderate, severe, profound, or total. Various other descriptors can be used depending on the shape of the audiogram, such as high frequency, low frequency, U-shaped, notched, peaked, or flat. ''Sensory'' hearing loss often occurs as a consequence of damaged or deficient cochlear hair cells. Hair cells may be abnormal at birth or damaged during the lifetime of an individual. There are both external causes of damage, including Ear infection, infection, and Ototoxicity, ototoxic drugs, as well as intrinsic causes, including genetic mutations. A common cause or exacerbating factor in SNHL is prolonged exposure to environmental noise, or noise-induced hearing loss. Ex ...
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Ramsay Hunt Syndrome Type 2
Ramsay Hunt syndrome type 2, commonly referred to simply as Ramsay Hunt syndrome (RHS) and also known as herpes zoster oticus, is inflammation of the geniculate ganglion of the facial nerve as a late consequence of '' varicella zoster virus'' (VZV). In regard to the frequency, less than 1% of varicella zoster infections involve the facial nerve and result in RHS. It is traditionally defined as a triad of ipsilateral facial paralysis, otalgia, and vesicles close to the ear and auditory canal. Due to its proximity to the vestibulocochlear nerve, the virus can spread and cause hearing loss, tinnitus (hearing noises that are not caused by outside sounds), and vertigo. It is common for diagnoses to be overlooked or delayed, which can raise the likelihood of long-term consequences. It is more complicated than Bell's palsy. Therapy aims to shorten its overall length, while also providing pain relief and averting any consequences. Signs and symptoms Early symptoms include intense p ...
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Geniculate Ganglion
The geniculate ganglion (from Latin ''genu'', for "knee") is a bilaterally paired special sense ganglion of the intermediate nerve component of the facial nerve (CN VII). It is situated within facial canal of the head. It contains cell bodies of first-order unipolar sensory neurons which convey gustatory (taste) afferents from taste receptors of the anterior two-thirds of the tongue by way of the chorda tympani, and of the palate by way of the greater petrosal nerve, From the ganglion, the proximal fibres proceed to the gustatory (i.e. superior/rostral) part of the solitary nucleus where they synapse with second-order neurons. Anatomy Structure The geniculate ganglion is conical in shape. The greater petrosal nerve diverges from CNVII and the lesser petrosal nerve diverges from CN IX at the geniculate ganglion. Relations It is located close to the internal auditory meatus. It is covered superiorly by the petrous part of the temporal bone (which is sometimes abse ...
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Varicella Zoster Virus
Varicella zoster virus (VZV), also known as human herpesvirus 3 (HHV-3, HHV3), is one of nine known herpes viruses that can infect humans. It causes chickenpox (varicella) commonly affecting children and young adults, and shingles (herpes zoster) in adults but rarely in children. As a late complication of VZV infection, Ramsay Hunt syndrome type 2 may develop in rare cases. VZV infections are species-specific to humans. The virus can survive in external environments for a few hours. VZV multiplies in the tonsils, and causes a wide variety of symptoms. Similar to the herpes simplex viruses, after primary infection with VZV (chickenpox), the virus lies dormant in neurons, including the cranial nerve ganglia, dorsal root ganglia, and autonomic ganglia. Many years after the person has recovered from initial chickenpox infection, VZV can ''reactivate'' to cause shingles. Epidemiology Chickenpox Primary varicella zoster virus infection results in chickenpox (varicella), whic ...
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Erythema Migrans
Erythema migrans or erythema chronicum migrans is an expanding rash often seen in the early stage of Lyme disease, and can also (but less commonly) be caused by southern tick-associated rash illness (STARI). Page last reviewed: October 22, 2015 It can appear anywhere from one day to one month after a tick bite. This rash does not represent an allergic reaction to the bite, but rather an actual skin infection of one of the Lyme bacteria species Lyme disease microbiology, from the genus ''Borrelia''. The rash's name comes from Neo-Latin for "migrating redness." Lyme disease "Erythema migrans is the only manifestation of Lyme disease in the United States that is sufficiently distinctive to allow clinical diagnosis in the absence of laboratory confirmation." Often, but not always, mentions of a target lesion (bull's-eye lesion) are talking about erythema migrans. However, the appearance of erythema migrans can vary considerably: while some look like a bull's eye, in the U.S. most ...
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Minnesota
Minnesota ( ) is a U.S. state, state in the Upper Midwestern region of the United States. It is bordered by the Canadian provinces of Manitoba and Ontario to the north and east and by the U.S. states of Wisconsin to the east, Iowa to the south, and North Dakota and South Dakota to the west. It is the List of U.S. states and territories by area, 12th-largest U.S. state in area and the List of U.S. states and territories by population, 22nd-most populous, with about 5.8 million residents. Minnesota is known as the "Land of 10,000 Lakes"; it has 14,420 bodies of fresh water covering at least ten acres each. Roughly a third of the state is Forest cover by state and territory in the United States, forested. Much of the remainder is prairie and farmland. More than 60% of Minnesotans (about 3.71 million) live in the Minneapolis–Saint Paul metropolitan area, known as the "Twin Cities", which is Minnesota's main Politics of Minnesota, political, Economy of Minnesota, economic, and C ...
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Wisconsin
Wisconsin ( ) is a U.S. state, state in the Great Lakes region, Great Lakes region of the Upper Midwest of the United States. It borders Minnesota to the west, Iowa to the southwest, Illinois to the south, Lake Michigan to the east, Michigan to the northeast, and Lake Superior to the north. With a population of about 6 million and an area of about 65,500 square miles, Wisconsin is the List of U.S. states and territories by population, 20th-largest state by population and the List of U.S. states and territories by area, 23rd-largest by area. It has List of counties in Wisconsin, 72 counties. Its List of municipalities in Wisconsin by population, most populous city is Milwaukee; its List of capitals in the United States, capital and second-most populous city is Madison, Wisconsin, Madison. Other urban areas include Green Bay, Wisconsin, Green Bay, Kenosha, Wisconsin, Kenosha, Racine, Wisconsin, Racine, Eau Claire, Wisconsin, Eau Claire, and the Fox Cities. Geography of Wiscon ...
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