FGE Serine-cysteine
FGE may refer to: * Fly Georgia, a defunct Georgian airline * Formylglycine-generating enzyme * Fruit Growers Express Fruit Growers Express (FGE) was a railroad refrigerator car leasing company that began as a produce-hauling subsidiary of Armour and Company's private refrigerator car line. Armour controlled both the packing operations and the transport insulate ...

Fly Georgia
FlyGeorgia ( ka, ფლაი ჯორჯია; IATA: FGE) was the second national airline of Georgia, with its headquarters in Tbilisi, beginning its operations in August 2012. It was a privately owned and controlled airline, which offered flights to a number of destinations in Europe, the Middle East and South Asia as well as in the CIS. As of the end of 2013, its operating license has been suspended. The company slogan was ''The World Awaits You.'' History Dubai, United Arab Emirates-based Iranians Hoshang Hosseinpour (born 21 March 1967, Tehran), Houshang Farsoudeh (born 10 October 1968, Tehran) and Pourya Nayebi (born 25 July 1974, Tehran) co-founded Fly Georgia in 2011. On 30 July 2012, it was officially announced that FlyGeorgia would start operating flights from Tbilisi to Batumi and the first flight would be launched on 3 August 2012. On 6 October 2012, it was officially stated that FGE would start direct flights from Tbilisi to Amsterdam with an Airbus A319. At th ...
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Formylglycine-generating Enzyme
Formylglycine-generating enzyme (FGE), located at 3p26.1 in humans, is the name for an enzyme present in the endoplasmic reticulum that catalyzes the conversion of cysteine to formylglycine (fGly). There are two main classes of FGE, aerobic and anaerobic. FGE activates sulfatases, which are essential for the degradation of sulfate esters. The catalytic activity of sulfatases is dependent upon a formylglycine (sometimes called oxoalanine) residue in the active site. Aerobic The aerobic enzyme has a structure homologous to the complex alpha/beta topology found in the gene product of human sulfatase-modifying factor 1 (SUMF1). Aerobic FGE converts a cysteine residue in the highly conserved consensus sequence CXPXR to fGly. To do so, FGE “activates” its target by utilizing mononuclear copper. The substrate first binds to copper, increasing reactivity of the substrate-copper complex with oxygen. Activation is then accomplished through oxidation of a cysteine residue in the substr ...
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