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Eyewire
''Eyewire'' is a citizen science game from Sebastian Seung's Lab at Princeton University. It is a human-based computation game that uses players to map retinal neurons. ''Eyewire'' launched on December 10, 2012. The game utilizes data generated by the Max Planck Institute for Medical Research. As of March 2025, ''Eyewire'' has had around 350,000 players and resulted in the tracing of 6,000 neurons. ''Eyewire'' gameplay is used for neuroscience research by enabling the reconstruction of morphological neuron data, which helps researchers model information-processing circuits. It is also used to generate a training dataset to further improve the artificial intelligence that assists the player through the gameplay. A later project spawned from ''Eyewire'' is the ''Flywire'' project, which used a similar but more selective citizen science system for its tracing and annotation. ''Flywire'' builds on ''Eyewire'' and used AIs trained on the dataset produced by ''Eyewire'' players. ''Fl ...
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Sebastian Seung
Hyunjune Sebastian Seung (English: /sung/ or əŋ ) was President at Samsung Electronics & Head of Samsung Research and is an Anthony B. Evnin Professor in the Princeton Neuroscience Institute and Department of Computer Science. Seung has done influential research in both computer science and neuroscience. He has helped pioneer the new field of connectomics, "developing new computational technologies for mapping the connections between neurons," and has been described as the cartographer of the brain. Since 2014, he has been a professor in computer science and neuroscience at Princeton University's Neuroscience Institute at the Jeff Bezos Center in Neural Dynamics, where he directs the Seung Labs. Before, he worked at the Massachusetts Institute of Technology as a full professor in computational neuroscience in the Department of Brain and Cognitive Sciences and as a professor in physics. In the industry, he was a research scientist at the Bell Labs and an Investigator of the ...
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Citizen Science
The term citizen science (synonymous to terms like community science, crowd science, crowd-sourced science, civic science, participatory monitoring, or volunteer monitoring) is research conducted with participation from the general public, or amateur/nonprofessional researchers or participants of science, social science and many other disciplines. There are variations in the exact definition of citizen science, with different individuals and organizations having their own specific interpretations of what citizen science encompasses. Citizen science is used in a wide range of areas of study including ecology, biology and conservation, health and medical research, astronomy, media and communications and information science. There are different applications and functions of "citizen science" in research projects. Citizen science can be used as a methodology where public volunteers help in collecting and classifying data, improving the scientific community's capacity. Citizen sc ...
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Retina
The retina (; or retinas) is the innermost, photosensitivity, light-sensitive layer of tissue (biology), tissue of the eye of most vertebrates and some Mollusca, molluscs. The optics of the eye create a focus (optics), focused two-dimensional image of the visual world on the retina, which then processes that image within the retina and sends nerve impulses along the optic nerve to the visual cortex to create visual perception. The retina serves a function which is in many ways analogous to that of the photographic film, film or image sensor in a camera. The neural retina consists of several layers of neurons interconnected by Chemical synapse, synapses and is supported by an outer layer of pigmented epithelial cells. The primary light-sensing cells in the retina are the photoreceptor cells, which are of two types: rod cell, rods and cone cell, cones. Rods function mainly in dim light and provide monochromatic vision. Cones function in well-lit conditions and are responsible fo ...
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Serial Block-face Scanning Electron Microscopy
Serial block-face scanning electron microscopy is a method to generate high resolution three-dimensional images from small samples. The technique was developed for brain tissue, but it is widely applicable for any biological samples. A serial block-face scanning electron microscope consists of an ultramicrotome mounted inside the vacuum chamber of a scanning electron microscope. Samples are prepared by methods similar to that in transmission electron microscopy ( TEM), typically by fixing the sample with aldehyde, staining with heavy metals such as osmium and uranium then embedding in an epoxy resin. The surface of the block of resin-embedded sample is imaged by detection of back-scattered electrons. Following imaging the ultramicrotome is used to cut a thin section (typically around 30 nm) from the face of the block. After the section is cut, the sample block is raised back to the focal plane and imaged again. This sequence of sample imaging, section cutting and block raising c ...
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Human-based Computation Game
A human-based computation game or game with a purpose (GWAP) is a human-based computation technique of outsourcing steps within a computational process to humans in an entertaining way (gamification). Luis von Ahn first proposed the idea of "human algorithm games", or games with a purpose (GWAPs), in order to harness human time and energy for addressing problems that computers cannot yet tackle on their own. He believes that human intellect is an important resource and contribution to the enhancement of computer processing and human computer interaction. He argues that games constitute a general mechanism for using brainpower to solve open computational problems. In this technique, human brains are compared to processors in a distributed system, each performing a small task of a massive computation. However, humans require an incentive to become part of a collective computation. Online games are used as a means to encourage participation in the process. The tasks presented in the ...
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Nature (journal)
''Nature'' is a British weekly scientific journal founded and based in London, England. As a multidisciplinary publication, ''Nature'' features Peer review, peer-reviewed research from a variety of academic disciplines, mainly in science and technology. It has core editorial offices across the United States, continental Europe, and Asia under the international scientific publishing company Springer Nature. ''Nature'' was one of the world's most cited scientific journals by the Science Edition of the 2022 ''Journal Citation Reports'' (with an ascribed impact factor of 50.5), making it one of the world's most-read and most prestigious academic journals. , it claimed an online readership of about three million unique readers per month. Founded in the autumn of 1869, ''Nature'' was first circulated by Norman Lockyer and Alexander MacMillan (publisher), Alexander MacMillan as a public forum for scientific innovations. The mid-20th century facilitated an editorial expansion for the j ...
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TED Conference
TED Conferences, LLC (Technology, Entertainment, Design) is an American-Canadian non-profit media organization that posts international talks online for free distribution under the slogan "Ideas Change Everything" (previously "Ideas Worth Spreading"). It was founded by Richard Saul Wurman and Harry Marks in February 1984 as a technology conference, in which Mickey Schulhof gave a demo of the compact disc that was invented in October 1982. Its main conference has been held annually since 1990. It covers almost all topics—from science to business to global issues—in more than 100 languages. TED's early emphasis was on technology and design, consistent with its Silicon Valley origins. It later broadened to include scientific, cultural, political, humanitarian, and academic topics. It has been curated by Chris Anderson, a British-American businessman, through the non-profit TED Foundation since July 2019 (originally by the non-profit Sapling Foundation). The main TED confere ...
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National Science Foundation
The U.S. National Science Foundation (NSF) is an Independent agencies of the United States government#Examples of independent agencies, independent agency of the Federal government of the United States, United States federal government that supports fundamental research and education in all the non-medical fields of science and engineering. Its medical counterpart is the National Institutes of Health. With an annual budget of about $9.9 billion (fiscal year 2023), the NSF funds approximately 25% of all federally supported basic research conducted by the List of American institutions of higher education, United States' colleges and universities. In some fields, such as mathematics, computer science, economics, and the social sciences, the NSF is the major source of federal backing. NSF's director and deputy director are appointed by the president of the United States and Advice and consent, confirmed by the United States Senate, whereas the 24 president-appointed members of the ...
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Wired (magazine)
''Wired'' is a bi-monthly American magazine that focuses on how emerging technologies affect culture, the economy, and politics. It is published in both print and Online magazine, online editions by Condé Nast. The magazine has been in publication since its launch in January 1993. Its editorial office is based in San Francisco, California, with its business headquarters located in New York City. ''Wired'' quickly became recognized as the voice of the emerging digital economy and culture and a pace setter in print design and web design. From 1998 until 2006, the magazine and its website, ''Wired.com'', experienced separate ownership before being fully consolidated under Condé Nast in 2006. It has won multiple National Magazine Awards and has been credited with shaping discourse around the digital revolution. The magazine also coined the term Crowdsourcing, ''crowdsourcing'', as well as its annual tradition of handing out Vaporware Awards. ''Wired'' has launched several in ...
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Morning Edition
''Morning Edition'' is an American radio news program produced and distributed by NPR. It airs weekday mornings (Monday through Friday) and runs for two hours, and many stations repeat one or both hours. The show feeds live from 5:00 to 9:00 a.m. ET, with feeds and updates as required until noon. The show premiered on November 5, 1979; its weekend counterpart is '' Weekend Edition''. ''Morning Edition'' and '' All Things Considered'' are among the highest rated public radio shows. The show was hosted by Bob Edwards from its inception until it was retooled for a two-anchor format in 2004 with the introduction of Steve Inskeep and Renée Montagne. Montagne left the show in 2016, and was replaced by Rachel Martin, who stepped down from daily hosting in early 2023. Four regular anchors, including Inskeep, currently host the show on a rotating basis. A Martínez, who hosts from NPR West, joined on July 19, 2021, replacing David Greene, who hosted from 2012 through the end of ...
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Forbes
''Forbes'' () is an American business magazine founded by B. C. Forbes in 1917. It has been owned by the Hong Kong–based investment group Integrated Whale Media Investments since 2014. Its chairman and editor-in-chief is Steve Forbes. The company is headquartered in Jersey City, New Jersey. Sherry Phillips is the current CEO of Forbes as of January 1, 2025. Published eight times per year, ''Forbes'' feature articles on finance, industry, investing, and marketing topics. It also reports on related subjects such as technology, communications, science, politics, and law. It has an international edition in Asia as well as editions produced under license in 27 countries and regions worldwide. The magazine is known for its lists and rankings, including its lists of the richest Americans (the Forbes 400, ''Forbes'' 400), of 30 notable people under the age of 30 (the Forbes 30 Under 30, ''Forbes'' 30 under 30), of America's wealthiest celebrities, of the world's top companies (the Fo ...
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Scientific American
''Scientific American'', informally abbreviated ''SciAm'' or sometimes ''SA'', is an American popular science magazine. Many scientists, including Albert Einstein and Nikola Tesla, have contributed articles to it, with more than 150 Nobel Prize-winners being featured since its inception. In print since 1845, it is the oldest continuously published magazine in the United States. ''Scientific American'' is owned by Springer Nature, which is a subsidiary of Holtzbrinck Publishing Group. History ''Scientific American'' was founded by inventor and publisher Rufus Porter (painter), Rufus Porter in 1845 as a four-page weekly newspaper. The first issue of the large-format New York City newspaper was released on August 28, 1845. Throughout its early years, much emphasis was placed on reports of what was going on at the United States Patent and Trademark Office, U.S. Patent Office. It also reported on a broad range of inventions including perpetual motion machines, an 1860 devi ...
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