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Evo-devo Gene Toolkit
The evo-devo gene toolkit is the small subset of genes in an organism's genome whose products control the organism's embryonic development. Toolkit genes are central to the synthesis of molecular genetics, palaeontology, evolution and developmental biology in the science of evolutionary developmental biology (evo-devo). Many of them are ancient and highly conserved among animal phyla. Toolkit Toolkit genes are highly conserved among phyla, meaning that they are ancient, dating back to the last common ancestor of bilaterian animals. For example, that ancestor had at least 7 Pax genes for transcription factors. Differences in deployment of toolkit genes affect the body plan and the number, identity, and pattern of body parts. The majority of toolkit genes are components of signaling pathways and encode for the production of transcription factors, cell adhesion proteins, cell surface receptor proteins (and signalling ligands that bind to them), and secreted morphogens; all of th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Body Plan
A body plan, (), or ground plan is a set of morphology (biology), morphological phenotypic trait, features common to many members of a phylum of animals. The vertebrates share one body plan, while invertebrates have many. This term, usually applied to animals, envisages a "blueprint" encompassing aspects such as symmetry (biology), symmetry, Germ layer, layers, segmentation (biology), segmentation, nerve, Limb (anatomy), limb, and Gastrointestinal tract, gut disposition. Evolutionary developmental biology seeks to explain the origins of diverse body plans. Body plans have historically been considered to have evolved in a flash in the Ediacaran biota; filling the Cambrian explosion with the results, and a more nuanced understanding of animal evolution suggests gradual development of body plans throughout the early Palaeozoic. Recent studies in animals and plants started to investigate whether evolutionary constraints on body plan structures can explain the presence of development ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Squamata
Squamata (, Latin ''squamatus'', 'scaly, having scales') is the largest Order (biology), order of reptiles; most members of which are commonly known as Lizard, lizards, with the group also including Snake, snakes. With over 11,991 species, it is also the second-largest order of Neontology, extant (living) vertebrates, after the Perciformes, perciform fish. Squamates are distinguished by their skins, which bear horny scale (zoology), scales or shields, and must periodically engage in molting. They also possess movable quadrate bones, making possible movement of the Maxilla, upper jaw relative to the neurocranium. This is particularly visible in snakes, which are able to open their mouths very widely to accommodate comparatively large prey. Squamates are the most variably sized living reptiles, ranging from the Sphaerodactylus ariasae, dwarf gecko (''Sphaerodactylus ariasae'') to the reticulated python (''Malayopython reticulatus''). The now-Extinction, extinct mosasaurs reached ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Snake
Snakes are elongated limbless reptiles of the suborder Serpentes (). Cladistically squamates, snakes are ectothermic, amniote vertebrates covered in overlapping scales much like other members of the group. Many species of snakes have skulls with several more joints than their lizard ancestors and relatives, enabling them to swallow prey much larger than their heads ( cranial kinesis). To accommodate their narrow bodies, snakes' paired organs (such as kidneys) appear one in front of the other instead of side by side, and most only have one functional lung. Some species retain a pelvic girdle with a pair of vestigial claws on either side of the cloaca. Lizards have independently evolved elongate bodies without limbs or with greatly reduced limbs at least twenty-five times via convergent evolution, leading to many lineages of legless lizards. These resemble snakes, but several common groups of legless lizards have eyelids and external ears, which snakes lack, althoug ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Bone Morphogenetic Protein
Bone morphogenetic proteins (BMPs) are a group of growth factors also known as cytokines and as metabologens. Professor Marshall Urist and Professor Hari Reddi discovered their ability to induce the formation of bone and cartilage, BMPs are now considered to constitute a group of pivotal morphogenetic signals, orchestrating tissue architecture throughout the body. The important functioning of BMP signals in physiology is emphasized by the multitude of roles for dysregulated BMP signalling in pathological processes. Cancerous disease often involves misregulation of the BMP signalling system. Absence of BMP signalling is, for instance, an important factor in the progression of colon cancer, and conversely, overactivation of BMP signalling following reflux-induced esophagitis provokes Barrett's esophagus and is thus instrumental in the development of esophageal adenocarcinoma. Recombinant human BMPs (rhBMPs) are used in orthopedic applications such as spinal fusions, nonunions, an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Large Ground-finch
The large ground finch (''Geospiza magnirostris'') is a species of bird in the genus Geospiza. One of Darwin's finches, it is now placed in the tanager family Thraupidae and was formerly in the Emberizidae. It is the largest species of Darwin's finch. Description The large ground finch weighs about 27-39 g, and its length ranges slightly 15-16 cm. It is the largest species of Darwin's finch both in total size and size of beak. The feather and bill colors vary between males and females. The adult male is mostly black, with slightly browner wings and tail; the cloaca is white-streaked; the eyes are dark brown. It also has blackish legs. The tail is relatively short. An adult female has browner feathers compared to a male, sometimes with yellow-brown or grey outer edges; scaled patterns are found going up the body; most parts of the torso and the head are streaked with brown and pale yellow shades. Beak It has a large beak, having a thick base of lower mandibles and curved cul ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Drosophila
''Drosophila'' (), from Ancient Greek δρόσος (''drósos''), meaning "dew", and φίλος (''phílos''), meaning "loving", is a genus of fly, belonging to the family Drosophilidae, whose members are often called "small fruit flies" or pomace flies, vinegar flies, or wine flies, a reference to the characteristic of many species to linger around overripe or rotting fruit. They should not be confused with the Tephritidae, a related family, which are also called fruit flies (sometimes referred to as "true fruit flies"); tephritids feed primarily on unripe or ripe fruit, with many species being regarded as destructive agricultural pests, especially the Mediterranean fruit fly. One species of ''Drosophila'' in particular, ''Drosophila melanogaster'', has been heavily used in research in genetics and is a common model organism in developmental biology. The terms "fruit fly" and "''Drosophila''" are often used synonymously with ''D. melanogaster'' in modern biological literatur ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Paradigm
In science and philosophy, a paradigm ( ) is a distinct set of concepts or thought patterns, including theories, research methods, postulates, and standards for what constitute legitimate contributions to a field. The word ''paradigm'' is Ancient Greek, Greek in origin, meaning "pattern". Etymology ''Paradigm'' comes from Greek παράδειγμα (''paradeigma''); "pattern, example, sample"; from the verb παραδείκνυμι (''paradeiknumi''); "exhibit, represent, expose"; and that from παρά (''para''); "beside, beyond"; and δείκνυμι (''deiknumi''); "to show, to point out". In classical (Greek-based) rhetoric, a paradeigma aims to provide an audience with an illustration of a similar occurrence. This illustration is not meant to take the audience to a conclusion; however, it is used to help guide them to get there. One way of how a ''paradeigma'' is meant to guide an audience would be exemplified by the role of a personal accountant. It is not the job of a p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Larva
A larva (; : larvae ) is a distinct juvenile form many animals undergo before metamorphosis into their next life stage. Animals with indirect development such as insects, some arachnids, amphibians, or cnidarians typically have a larval phase of their life cycle. A larva's appearance is generally very different from the adult form (''e.g.'' caterpillars and butterflies) including different unique structures and organs that do not occur in the adult form. Their diet may also be considerably different. In the case of smaller primitive arachnids, the larval stage differs by having three instead of four pairs of legs. Larvae are frequently adapted to different environments than adults. For example, some larvae such as tadpoles live almost exclusively in aquatic environments but can live outside water as adult frogs. By living in a distinct environment, larvae may be given shelter from predators and reduce competition for resources with the adult population. Animals in the lar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Embryo
An embryo ( ) is the initial stage of development for a multicellular organism. In organisms that reproduce sexually, embryonic development is the part of the life cycle that begins just after fertilization of the female egg cell by the male sperm cell. The resulting fusion of these two cells produces a single-celled zygote that undergoes many cell divisions that produce cells known as blastomeres. The blastomeres (4-cell stage) are arranged as a solid ball that when reaching a certain size, called a morula, (16-cell stage) takes in fluid to create a cavity called a blastocoel. The structure is then termed a blastula, or a blastocyst in mammals. The mammalian blastocyst hatches before implantating into the endometrial lining of the womb. Once implanted the embryo will continue its development through the next stages of gastrulation, neurulation, and organogenesis. Gastrulation is the formation of the three germ layers that will form all of the different parts of t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Anatomy
Anatomy () is the branch of morphology concerned with the study of the internal structure of organisms and their parts. Anatomy is a branch of natural science that deals with the structural organization of living things. It is an old science, having its beginnings in prehistoric times. Anatomy is inherently tied to developmental biology, embryology, comparative anatomy, evolutionary biology, and phylogeny, as these are the processes by which anatomy is generated, both over immediate and long-term timescales. Anatomy and physiology, which study the structure and function of organisms and their parts respectively, make a natural pair of related disciplines, and are often studied together. Human anatomy is one of the essential basic sciences that are applied in medicine, and is often studied alongside physiology. Anatomy is a complex and dynamic field that is constantly evolving as discoveries are made. In recent years, there has been a significant increase in the use of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |