Eugène Millon
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Eugène Millon
Eugène Auguste Nicolas Millon (24 April 1812 – 22 October 1867) was a French chemist and physician. He is remembered in the name of Millon's reagent which reacts with tyrosine in proteins to form a brown precipitate. The reagent is used for determination of the presence of soluble proteins. Millon was born in Saint-Seine-l'Abbaye and after his education, he taught briefly at the Collège Rollin after before training in medicine at the military hospital at Val-de-Grâce from 1832 to 1835. After serving for a while in the army he left surgery to study pharmacy and chemistry and became a pharmacist in 1838, serving from 1850 to 1865 in Algeria. His most well-known contribution was the reaction of mercury and nitric acid with egg albumen which produces a white precipitate that turns red on heating. His other contributions were on compounds of chlorine and iodine including the acids. He examined salts in blood. An Algerian stamp commemorating him was released in 1954. See Al ...
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E Millon
E, or e, is the fifth letter and the second vowel letter of the Latin alphabet, used in the modern English alphabet, the alphabets of other western European languages and others worldwide. Its name in English is ''e'' (pronounced ); plural ''es'', ''Es'', or ''E's''. It is the most commonly used letter in many languages, including Czech, Danish, Dutch, English, French, German, Hungarian, Latin, Latvian, Norwegian, Spanish, and Swedish. Name In English, the name of the letter is the "long E" sound, pronounced . In most other languages, its name matches the letter's pronunciation in open syllables. History The Latin letter 'E' differs little from its source, the Greek letter epsilon, 'Ε'. This in turn comes from the Semitic letter '' hê'', which has been suggested to have started as a praying or calling human figure (''hillul'', 'jubilation'), and was most likely based on a similar Egyptian hieroglyph that indicated a different pronunciation. In Semitic, th ...
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Millon's Reagent
Millon's reagent is an analytical reagent used to detect the presence of soluble proteins. A few drops of the reagent are added to the test solution, which is then heated gently. A reddish-brown coloration or precipitate indicates the presence of tyrosine residue which occur in nearly all proteins. The test was developed by the French chemist Auguste Nicolas Eugene Millon. The structure of the metal complex is usually misrepresented. It is an nitroso complex, with M-N bonds. The reagent is made by dissolving metallic mercury in nitric acid and diluting with water, forming mercuric nitrate (Hg O3sub>2). In the test, the phenol group in the side chain of tyrosine gets nitrated, and that product then complexes with Hg(I) or Hg(II) ions to give a red colored precipitate. Millon's test is not specific for proteins; it also gives a positive test for other compounds containing the phenol functional group In organic chemistry, a functional group is any substituent or moiety (chem ...
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Tyrosine
-Tyrosine or tyrosine (symbol Tyr or Y) or 4-hydroxyphenylalanine is one of the 20 standard amino acids that are used by cells to synthesize proteins. It is a conditionally essential amino acid with a polar side group. The word "tyrosine" is from the Greek ''tyrós'', meaning ''cheese'', as it was first discovered in 1846 by German chemist Justus von Liebig in the protein casein from cheese. It is called tyrosyl when referred to as a functional group or side chain. While tyrosine is generally classified as a hydrophobic amino acid, it is more hydrophilic than phenylalanine. It is encoded by the codons UAC and UAU in messenger RNA. The one-letter symbol Y was assigned to tyrosine for being alphabetically nearest of those letters available. Note that T was assigned to the structurally simpler threonine, U was avoided for its similarity with V for valine, W was assigned to tryptophan, while X was reserved for undetermined or atypical amino acids. The mnemonic t''Y''rosine was ...
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Saint-Seine-l'Abbaye
Saint-Seine-l'Abbaye () is a commune in the Côte-d'Or department in eastern France. It is also a place steeped in history with its archaeological sites, the goddess Sequana; nymph Sources close to the Seine and Alesia, the remnants of its ancient abbey (the Abbey of Saint-Seine) and the abbey church, a jewel of Gothic art primitive Burgundy and its rich rural heritage: the 1856 school converted into a museum, flower laundries, foundries, crucifixes, mills. The abbey was founded by Saint Sequanus in the 6th century. Population See also *Communes of the Côte-d'Or department The following is a list of the 698 communes of the Côte-d'Or department of France. The communes cooperate in the following intercommunalities (as of 2025):Communes o ...
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Collège-lycée Jacques-Decour
The Collège-lycée Jacques-Decour () is a school in Paris, France, on avenue Trudaine. History The school was founded as the private Collège Sainte-Barbe in 1821 and renamed Collège Rollin in 1830. It was transplanted in 1876 from the Quartier Latin to avenue Trudaine, near Montmartre. The old building on rue Lhomond became the site of the Protestant Faculty of Theology in Paris in 1877. Collège Rollin was granted municipal status, and became Lycée Rollin in 1919. It is the only secondary school in Paris to have taken the name of a former teacher, Jacques Decour, a French Resistance fighter in 1944. Selected alumni * Daniel Bilalian * Jean de Botton * Charles Forbes René de Montalembert * Lucien Lévy * Benoît Mandelbrot * Édouard Manet Édouard Manet (, ; ; 23 January 1832 – 30 April 1883) was a French Modernism, modernist painter. He was one of the first 19th-century artists to paint modern life, as well as a pivotal figure in the transition from Realism ( ...
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Millon's Base
Mercuric amidochloride is an inorganic compound with the formula . Preparation and properties It arises from the reaction of mercury(II) chloride and ammonia (Calomel reaction), where the resulting mercuric amidochloride is highly insoluble. It forms white crystals in the shape of small prisms. It tastes earthy and metallic, but is a deadly poison and should not be ingested. At the molecular level, it organizes as a zig-zag 1-dimensional polymer with chloride counterions. It is stable in air, but darkens on exposure to light. It does not melt, even at dull red heat, instead subliming and decomposing to gaseous mercury, hydrogen chloride, and nitrogen oxides. Consequently sealed containers with this chemical may explode when heated. The substance is a deadly poison, although not a carcinogen. It is toxic unto lethality by inhalation, ingestion or dermal absorption. In lesser cases, it may instead cause dermatitis and skin lesions or corrode the mucous membranes. If i ...
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1812 Births
Events January–March * January 1 – The ''Allgemeines bürgerliches Gesetzbuch'' (the Austrian civil code) enters into force in the Austrian Empire. * January 19 – Peninsular War: The French-held fortress of Ciudad Rodrigo Siege of Ciudad Rodrigo (1812), is stormed by the Anglo-Portuguese Army, under the Arthur Wellesley, 1st Duke of Wellington, Earl of Wellington. * February 7 – The last 1811–12 New Madrid earthquakes, New Madrid earthquake strikes New Madrid, Missouri, with an estimated moment magnitude scale, moment magnitude of over 8. * February 12 – Napoleon authorizes the usage of ''Mesures usuelles'', the basis of the metric system. * February 13 – The first Chilean newspaper ''Aurora de Chile'' deals with political philosophy, and stands in favor of the new national government. * February 27 ** Argentine War of Independence: Manuel Belgrano raises the Flag of Argentina (which he designed) in the city of Rosario, for the first time. ** English poet ...
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1867 Deaths
There were only 354 days this year in the newly purchased territory of Alaska. When the territory transferred from the Russian Empire to the United States, the calendric transition from the Julian to the Gregorian Calendar was made with only 11 days instead of 12 during the 19th century. This change was made due to the territorial and geopolitical shift from the Asian to the American side of the International Date Line. Friday, 6 October 1867 ''(Julian Calendar)'' was followed by Friday again on 18 October 1867 (instead of Saturday, 19 October 1867 in the Gregorian Calendar). Events January * January 1 – The Covington–Cincinnati Suspension Bridge opens between Cincinnati, Ohio, and Covington, Kentucky, in the United States, becoming the longest single-span bridge in the world. It was renamed after its designer, John A. Roebling, in 1983. * January 8 – African-American men are granted the right to vote in the District of Columbia. * January 11 – Benito Ju� ...
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19th-century French Chemists
The 19th century began on 1 January 1801 (represented by the Roman numerals MDCCCI), and ended on 31 December 1900 (MCM). It was the 9th century of the 2nd millennium. It was characterized by vast social upheaval. Slavery was Abolitionism, abolished in much of Europe and the Americas. The First Industrial Revolution, though it began in the late 18th century, expanded beyond its British homeland for the first time during the 19th century, particularly remaking the economies and societies of the Low Countries, France, the Rhineland, Northern Italy, and the Northeastern United States. A few decades later, the Second Industrial Revolution led to ever more massive urbanization and much higher levels of productivity, profit, and prosperity, a pattern that continued into the 20th century. The Catholic Church, in response to the growing influence and power of modernism, secularism and materialism, formed the First Vatican Council in the late 19th century to deal with such problems an ...
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