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Ernest Kennaway
Sir Ernest Laurence Kennaway FRS (23 May 1881 – 1 January 1958) was a British pathologist and Royal Medal winner. He first became interested in natural life when, due to a childhood illness, he was encouraged to spend time outdoors. He was trained at University College London, and in 1898 was accepted into New College, Oxford on an open scholarship to study natural sciences. He graduated with a B.A. in 1903, and after three years at Middlesex Hospital he completed a Bachelor of Medicine and Surgery. After graduating he worked for The Lister Institute for Preventive Medicine and UCL before returning to Oxford, this time to Brasenose College on a Hulme scholarship in 1909. He became a Travelling Fellow of Brasenose in 1910, a Doctor of Medicine in 1911 and a Doctor of Science (specifically physiological chemistry) in 1915. In 1909 he became a physiology demonstrator at Guy's Hospital, where he remained until he was made head of the department of chemical pathology at the Bland-S ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Exeter
Exeter ( ) is a City status in the United Kingdom, cathedral city and the county town of Devon in South West England. It is situated on the River Exe, approximately northeast of Plymouth and southwest of Bristol. In Roman Britain, Exeter was established as the base of Legio II Augusta under the personal command of Vespasian. Exeter became a religious centre in the Middle Ages. Exeter Cathedral, founded in the mid 11th century, became Anglicanism, Anglican in the 16th-century English Reformation. Exeter became an affluent centre for the wool trade, although by the First World War the city was in decline. After the Second World War, much of the city centre was rebuilt and is now a centre for education, business and tourism in Devon and Cornwall. It is home to two of the constituent campuses of the University of Exeter: Streatham Campus, Streatham and St Luke's Campus, St Luke's. The administrative area of Exeter has the status of a non-metropolitan district under the administ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Purine Metabolism
Purine metabolism refers to the metabolic pathways to synthesize and break down purines that are present in many organisms. Biosynthesis Purines are biologically synthesized as nucleotides and in particular as ribotides, i.e. bases attached to ribose 5-phosphate. Both adenine and guanine are derived from the nucleotide inosine monophosphate (IMP), which is the first compound in the pathway to have a completely formed purine ring system. IMP Inosine monophosphate is synthesized on a pre-existing ribose-phosphate through a complex pathway (as shown in the figure on the right). The source of the carbon and nitrogen atoms of the purine ring, 5 and 4 respectively, come from multiple sources. The amino acid glycine contributes all its carbon (2) and nitrogen (1) atoms, with additional nitrogen atoms from glutamine (2) and aspartic acid (1), and additional carbon atoms from formyl groups (2), which are transferred from the coenzyme tetrahydrofolate as 10-formyltetrahydrofolate, and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
British Pathologists
British may refer to: Peoples, culture, and language * British people, nationals or natives of the United Kingdom, British Overseas Territories and Crown Dependencies. * British national identity, the characteristics of British people and culture * British English, the English language as spoken and written in United Kingdom of Great Britain and Northern Ireland and, more broadly, throughout the British Isles * Celtic Britons, an ancient ethno-linguistic group * Brittonic languages, a branch of the Insular Celtic language family (formerly called British) ** Common Brittonic, an ancient language Other uses *People or things associated with: ** Great Britain, an island ** British Isles, an island group ** United Kingdom, a sovereign state ** British Empire, a historical global colonial empire ** Kingdom of Great Britain (1707–1800) ** United Kingdom of Great Britain and Ireland (1801–1922) * British Raj, colonial India under the British Empire * British Hong Kong, colonial H ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1958 Deaths
Events January * January 1 – The European Economic Community (EEC) comes into being. * January 3 – The West Indies Federation is formed. * January 4 ** Edmund Hillary's Commonwealth Trans-Antarctic Expedition completes the third overland journey to the South Pole, the first to use powered vehicles. ** Sputnik 1 (launched on October 4, 1957) falls towards Earth from its orbit and burns up. * January 13 – Battle of Edchera: The Moroccan Army of Liberation ambushes a Spanish patrol. * January 27 – A Soviet-American executive agreement on cultural, educational and scientific exchanges, also known as the "Lacy-Zarubin Agreement, Lacy–Zarubin Agreement", is signed in Washington, D.C. February * February 1 – Egypt and Syria unite to form the United Arab Republic. * February 2 – The ''Falcons'' aerobatic team of the Pakistan Air Force led by Wg Cdr Zafar Masud (air commodore), Mitty Masud set a World record loop, world record performing a 16 aircraft diamon ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1881 Births
Events January * January 1– 24 – Siege of Geok Tepe: Russian troops under General Mikhail Skobelev defeat the Turkomans. * January 13 – War of the Pacific – Battle of San Juan and Chorrillos: The Chilean army defeats Peruvian forces. * January 15 – War of the Pacific – Battle of Miraflores: The Chileans take Lima, capital of Peru, after defeating its second line of defense in Miraflores. * January 24 – William Edward Forster, chief secretary for Ireland, introduces his Coercion Bill, which temporarily suspends habeas corpus so that those people suspected of committing an offence can be detained without trial; it goes through a long debate before it is accepted February 2. Note that Coercion bills had been passed almost annually in the 19th century, with a total of 105 such bills passed from 1801 to 1921. * January 25 – Thomas Edison and Alexander Graham Bell form the Oriental Telephone Company. February * Febru ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Parkinson's Disease
Parkinson's disease (PD), or simply Parkinson's, is a neurodegenerative disease primarily of the central nervous system, affecting both motor system, motor and non-motor systems. Symptoms typically develop gradually and non-motor issues become more prevalent as the disease progresses. The motor symptoms are collectively called parkinsonism and include tremors, bradykinesia, spasticity, rigidity as well as postural instability (i.e., difficulty maintaining balance). Non-motor symptoms develop later in the disease and include behavior change (individual), behavioral changes or mental disorder, neuropsychiatric problems such as sleep abnormalities, psychosis, anosmia, and mood swings. Most Parkinson's disease cases are idiopathic disease, idiopathic, though contributing factors have been identified. Pathophysiology involves progressive nerve cell death, degeneration of nerve cells in the substantia nigra, a midbrain region that provides dopamine to the basal ganglia, a system invo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Case–control Study
A case–control study (also known as case–referent study) is a type of observational study in which two existing groups differing in outcome are identified and compared on the basis of some supposed causal attribute. Case–control studies are often used to identify factors that may contribute to a medical condition by comparing subjects who have the condition with patients who do not have the condition but are otherwise similar. They require fewer resources but provide less evidence for causal inference than a randomized controlled trial. A case–control study is often used to produce an odds ratio. Some statistical methods make it possible to use a case–control study to also estimate relative risk, risk differences, and other quantities. Definition Porta's ''Dictionary of Epidemiology'' defines the case–control study as: "an observational epidemiological study of persons with the disease (or another outcome variable) of interest and a suitable control group of persons wi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Air Pollution
Air pollution is the presence of substances in the Atmosphere of Earth, air that are harmful to humans, other living beings or the environment. Pollutants can be Gas, gases like Ground-level ozone, ozone or nitrogen oxides or small particles like soot and dust. It affects both outdoor air and indoor air. Natural sources of air pollution include Wildfire, wildfires, Dust storm, dust storms, and Volcanic eruption, volcanic eruptions. Indoor air pollution is often Energy poverty and cooking, caused by the use of biomass (e.g. wood) for cooking and heating. Outdoor air pollution comes from some industrial processes, the burning of Fossil fuel, fossil fuels for electricity and transport, waste management and agriculture. Many of the contributors of local air pollution, especially the burning of fossil fuels, also cause greenhouse gas emissions that cause climate change, global warming. Air pollution causes around 7 or 8 million deaths each year. It is a significant risk factor for ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Medical Research Council (United Kingdom)
The Medical Research Council (MRC) is responsible for co-coordinating and funding medical research in the United Kingdom. It is part of United Kingdom Research and Innovation (UKRI), which came into operation 1 April 2018, and brings together the UK's seven research councils, Innovate UK and Research England. UK Research and Innovation is answerable to, although politically independent from, the Department for Business, Energy and Industrial Strategy. The MRC focuses on high-impact research and has provided the financial support and scientific expertise behind a number of medical breakthroughs, including the development of penicillin and the discovery of the structure of DNA. Research funded by the MRC has produced 32 Nobel Prize winners to date. History The MRC was founded as the Medical Research Committee and Advisory Council in 1913, with its prime role being the distribution of medical research funds under the terms of the National Insurance Act 1911. This was a conseq ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Polycyclic Aromatic Hydrocarbon
A Polycyclic aromatic hydrocarbon (PAH) is any member of a class of organic compounds that is composed of multiple fused aromatic rings. Most are produced by the incomplete combustion of organic matter— by engine exhaust fumes, tobacco, incinerators, in roasted meats and cereals, or when biomass burns at lower temperatures as in forest fires. The simplest representative is naphthalene, having two aromatic rings, and the three-ring compounds anthracene and phenanthrene. PAHs are uncharged, non-polar and planar. Many are colorless. Many of them are also found in fossil fuel deposits such as coal and in petroleum. Exposure to PAHs can lead to different types of cancer, to fetal development complications, and to cardiovascular issues. Polycyclic aromatic hydrocarbons are discussed as possible starting materials for abiotic syntheses of materials required by the earliest forms of life. Nomenclature and structure The terms polyaromatic hydrocarbon, or polynuclear aromatic hydro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Izrael Hieger
Izrael Hieger DSc (London) (13 June 1901 – 14 October 1986) was a biochemist whose work focused on carcinogenesis. He discovered the first known organic carcinogenic compound. In 1937 Hieger, with colleagues Ernest Kennaway and J. W. Cook, was nominated for a Nobel Prize for work on isolating chemical carcinogenic agents from tar and studies on the relation between chemical constitution and carcinogenic activity. Early life Hieger was born in Siedlce, Russian Empire (present Republic of Poland), to parents Francis Ephroim and Helena Chaje Heiger and was the youngest of nine. Preempting the pogrom of 1906, Heiger's parents emigrated with the younger children, settling in London. There he attended Christ's College, Finchley, going on to study at Birkbeck, University of London and University College London. Heiger married Esther (née Bull), and although not a member, financially assisted a Trotskyist group in London run by C.L.R. James, of which Esther and her future husband E ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
